JP2006166853A5 - - Google Patents
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- Publication number
- JP2006166853A5 JP2006166853A5 JP2004366914A JP2004366914A JP2006166853A5 JP 2006166853 A5 JP2006166853 A5 JP 2006166853A5 JP 2004366914 A JP2004366914 A JP 2004366914A JP 2004366914 A JP2004366914 A JP 2004366914A JP 2006166853 A5 JP2006166853 A5 JP 2006166853A5
- Authority
- JP
- Japan
- Prior art keywords
- lactic acid
- methane production
- production inhibitor
- acid bacteria
- leuconostoc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 134
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical compound C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 claims description 134
- 241000894006 Bacteria Species 0.000 claims description 96
- 239000004310 lactic acid Substances 0.000 claims description 67
- 235000014655 lactic acid Nutrition 0.000 claims description 67
- 108091005804 Peptidases Proteins 0.000 claims description 56
- 239000004365 Protease Substances 0.000 claims description 55
- 238000004519 manufacturing process Methods 0.000 claims description 55
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims description 47
- 241000282849 Ruminantia Species 0.000 claims description 38
- 239000003112 inhibitor Substances 0.000 claims description 35
- 108010062877 Bacteriocins Proteins 0.000 claims description 34
- 238000000034 method Methods 0.000 claims description 33
- 239000000203 mixture Substances 0.000 claims description 18
- 241000192132 Leuconostoc Species 0.000 claims description 13
- 241000186660 Lactobacillus Species 0.000 claims description 12
- 241000191996 Pediococcus pentosaceus Species 0.000 claims description 10
- 241000192001 Pediococcus Species 0.000 claims description 9
- 229940039696 lactobacillus Drugs 0.000 claims description 8
- 239000004480 active ingredient Substances 0.000 claims description 7
- 239000012228 culture supernatant Substances 0.000 claims description 7
- 240000006024 Lactobacillus plantarum Species 0.000 claims description 6
- 235000013965 Lactobacillus plantarum Nutrition 0.000 claims description 6
- 238000011161 development Methods 0.000 claims description 6
- 229940072205 lactobacillus plantarum Drugs 0.000 claims description 6
- 241001468192 Leuconostoc citreum Species 0.000 claims description 5
- 241000192130 Leuconostoc mesenteroides Species 0.000 claims description 5
- 241000186869 Lactobacillus salivarius Species 0.000 claims description 4
- 241000186684 Lactobacillus pentosus Species 0.000 claims description 3
- 230000000844 anti-bacterial effect Effects 0.000 description 36
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 32
- 210000004767 rumen Anatomy 0.000 description 31
- 238000012360 testing method Methods 0.000 description 31
- 239000000243 solution Substances 0.000 description 25
- 239000002609 medium Substances 0.000 description 21
- 239000000523 sample Substances 0.000 description 17
- 239000001569 carbon dioxide Substances 0.000 description 16
- 229910002092 carbon dioxide Inorganic materials 0.000 description 16
- 229920001817 Agar Polymers 0.000 description 14
- 239000008272 agar Substances 0.000 description 14
- 230000000694 effects Effects 0.000 description 10
- 108010053775 Nisin Proteins 0.000 description 9
- NVNLLIYOARQCIX-MSHCCFNRSA-N Nisin Chemical compound N1C(=O)[C@@H](CC(C)C)NC(=O)C(=C)NC(=O)[C@@H]([C@H](C)CC)NC(=O)[C@@H](NC(=O)C(=C/C)/NC(=O)[C@H](N)[C@H](C)CC)CSC[C@@H]1C(=O)N[C@@H]1C(=O)N2CCC[C@@H]2C(=O)NCC(=O)N[C@@H](C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(NCC(=O)N[C@H](C)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCSC)C(=O)NCC(=O)N[C@H](CS[C@@H]2C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H](CCSC)C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(N[C@H](C)C(=O)N[C@@H]3C(=O)N[C@@H](C(N[C@H](CC=4NC=NC=4)C(=O)N[C@H](CS[C@@H]3C)C(=O)N[C@H](CO)C(=O)N[C@H]([C@H](C)CC)C(=O)N[C@H](CC=3NC=NC=3)C(=O)N[C@H](C(C)C)C(=O)NC(=C)C(=O)N[C@H](CCCCN)C(O)=O)=O)CS[C@@H]2C)=O)=O)CS[C@@H]1C NVNLLIYOARQCIX-MSHCCFNRSA-N 0.000 description 9
- 102000035195 Peptidases Human genes 0.000 description 9
- 239000004309 nisin Substances 0.000 description 9
- 235000010297 nisin Nutrition 0.000 description 9
- 102000004190 Enzymes Human genes 0.000 description 8
- 229940088598 enzyme Drugs 0.000 description 8
- 244000057717 Streptococcus lactis Species 0.000 description 7
- 235000014897 Streptococcus lactis Nutrition 0.000 description 7
- 230000009036 growth inhibition Effects 0.000 description 7
- 239000007788 liquid Substances 0.000 description 7
- 244000005700 microbiome Species 0.000 description 7
- 244000063299 Bacillus subtilis Species 0.000 description 6
- 235000014469 Bacillus subtilis Nutrition 0.000 description 6
- 108090000790 Enzymes Proteins 0.000 description 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- 239000006872 mrs medium Substances 0.000 description 6
- 241000283690 Bos taurus Species 0.000 description 5
- 238000012258 culturing Methods 0.000 description 5
- 238000000855 fermentation Methods 0.000 description 5
- 230000004151 fermentation Effects 0.000 description 5
- 235000013305 food Nutrition 0.000 description 5
- 239000006228 supernatant Substances 0.000 description 5
- 241000228212 Aspergillus Species 0.000 description 4
- 241000186612 Lactobacillus sakei Species 0.000 description 4
- 238000010790 dilution Methods 0.000 description 4
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- 235000021107 fermented food Nutrition 0.000 description 4
- 238000000338 in vitro Methods 0.000 description 4
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- 240000006439 Aspergillus oryzae Species 0.000 description 3
- 235000002247 Aspergillus oryzae Nutrition 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 3
- 241000193749 Bacillus coagulans Species 0.000 description 3
- 241000192003 Leuconostoc carnosum Species 0.000 description 3
- 241000202221 Weissella Species 0.000 description 3
- 102000004139 alpha-Amylases Human genes 0.000 description 3
- 108090000637 alpha-Amylases Proteins 0.000 description 3
- 229940024171 alpha-amylase Drugs 0.000 description 3
- 229940054340 bacillus coagulans Drugs 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 230000037396 body weight Effects 0.000 description 3
- 229920002301 cellulose acetate Polymers 0.000 description 3
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- 241000605900 Butyrivibrio fibrisolvens Species 0.000 description 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 241001468196 Leuconostoc pseudomesenteroides Species 0.000 description 2
- 241000186805 Listeria innocua Species 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 241001494479 Pecora Species 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 108010046377 Whey Proteins Proteins 0.000 description 2
- 102000007544 Whey Proteins Human genes 0.000 description 2
- 240000008042 Zea mays Species 0.000 description 2
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 2
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 2
- 230000000903 blocking effect Effects 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 2
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- 235000005822 corn Nutrition 0.000 description 2
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- 238000011156 evaluation Methods 0.000 description 2
- 230000001747 exhibiting effect Effects 0.000 description 2
- 239000005431 greenhouse gas Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 235000013372 meat Nutrition 0.000 description 2
- 230000000696 methanogenic effect Effects 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 238000001543 one-way ANOVA Methods 0.000 description 2
- 239000000546 pharmaceutical excipient Substances 0.000 description 2
- 238000004321 preservation Methods 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 239000012138 yeast extract Substances 0.000 description 2
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- 241000193752 Bacillus circulans Species 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 102000005600 Cathepsins Human genes 0.000 description 1
- 108010084457 Cathepsins Proteins 0.000 description 1
- 235000019750 Crude protein Nutrition 0.000 description 1
- 241000194033 Enterococcus Species 0.000 description 1
- 241000194031 Enterococcus faecium Species 0.000 description 1
- 241001106597 Enterococcus lactis Species 0.000 description 1
- 239000004606 Fillers/Extenders Substances 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 241000192129 Leuconostoc lactis Species 0.000 description 1
- 241000186781 Listeria Species 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 240000004658 Medicago sativa Species 0.000 description 1
- 235000017587 Medicago sativa ssp. sativa Nutrition 0.000 description 1
- 241000192041 Micrococcus Species 0.000 description 1
- 241000191938 Micrococcus luteus Species 0.000 description 1
- 229930191564 Monensin Natural products 0.000 description 1
- GAOZTHIDHYLHMS-UHFFFAOYSA-N Monensin A Natural products O1C(CC)(C2C(CC(O2)C2C(CC(C)C(O)(CO)O2)C)C)CCC1C(O1)(C)CCC21CC(O)C(C)C(C(C)C(OC)C(C)C(O)=O)O2 GAOZTHIDHYLHMS-UHFFFAOYSA-N 0.000 description 1
- 229910002651 NO3 Inorganic materials 0.000 description 1
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 description 1
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 241001129622 Planodes virginica Species 0.000 description 1
- 241000605860 Prevotella ruminicola Species 0.000 description 1
- 241000606008 Ruminobacter amylophilus Species 0.000 description 1
- 235000015503 Sorghum bicolor subsp. drummondii Nutrition 0.000 description 1
- 244000064817 Sorghum halepense var. sudanense Species 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 241001493546 Suina Species 0.000 description 1
- 241000975185 Weissella cibaria Species 0.000 description 1
- 241000202218 Weissella hellenica Species 0.000 description 1
- 241000186837 Weissella kandleri Species 0.000 description 1
- 241000186864 Weissella minor Species 0.000 description 1
- 241000192133 Weissella paramesenteroides Species 0.000 description 1
- 241000028633 Weissella thailandensis Species 0.000 description 1
- 239000005862 Whey Substances 0.000 description 1
- 238000012870 ammonium sulfate precipitation Methods 0.000 description 1
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- 230000000845 anti-microbial effect Effects 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
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- 239000000872 buffer Substances 0.000 description 1
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- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- 159000000007 calcium salts Chemical class 0.000 description 1
- 229940041514 candida albicans extract Drugs 0.000 description 1
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- 235000015140 cultured milk Nutrition 0.000 description 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 description 1
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- 238000012869 ethanol precipitation Methods 0.000 description 1
- BEFDCLMNVWHSGT-UHFFFAOYSA-N ethenylcyclopentane Chemical compound C=CC1CCCC1 BEFDCLMNVWHSGT-UHFFFAOYSA-N 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 235000011194 food seasoning agent Nutrition 0.000 description 1
- 239000001530 fumaric acid Substances 0.000 description 1
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- 239000008103 glucose Substances 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
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- 230000000670 limiting effect Effects 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
- 159000000003 magnesium salts Chemical class 0.000 description 1
- 150000002696 manganese Chemical class 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000012533 medium component Substances 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 229960005358 monensin Drugs 0.000 description 1
- GAOZTHIDHYLHMS-KEOBGNEYSA-N monensin A Chemical compound C([C@@](O1)(C)[C@H]2CC[C@@](O2)(CC)[C@H]2[C@H](C[C@@H](O2)[C@@H]2[C@H](C[C@@H](C)[C@](O)(CO)O2)C)C)C[C@@]21C[C@H](O)[C@@H](C)[C@@H]([C@@H](C)[C@@H](OC)[C@H](C)C(O)=O)O2 GAOZTHIDHYLHMS-KEOBGNEYSA-N 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
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- 229920001778 nylon Polymers 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 235000021317 phosphate Nutrition 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
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- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
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- 235000020083 shōchū Nutrition 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
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- 239000004334 sorbic acid Substances 0.000 description 1
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- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000021119 whey protein Nutrition 0.000 description 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004366914A JP2006166853A (ja) | 2004-12-17 | 2004-12-17 | 反芻動物用のメタン生成抑制剤および飼料組成物 |
| EP05027599A EP1673983A1 (en) | 2004-12-17 | 2005-12-16 | A methane production reducer, and feed composition for ruminant |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004366914A JP2006166853A (ja) | 2004-12-17 | 2004-12-17 | 反芻動物用のメタン生成抑制剤および飼料組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006166853A JP2006166853A (ja) | 2006-06-29 |
| JP2006166853A5 true JP2006166853A5 (enExample) | 2008-04-03 |
Family
ID=36130083
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004366914A Withdrawn JP2006166853A (ja) | 2004-12-17 | 2004-12-17 | 反芻動物用のメタン生成抑制剤および飼料組成物 |
Country Status (2)
| Country | Link |
|---|---|
| EP (1) | EP1673983A1 (enExample) |
| JP (1) | JP2006166853A (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1862080A1 (en) * | 2006-05-31 | 2007-12-05 | Ajinomoto Co., Inc. | Protease-resistant bacteriocins produced by lactic acid bacteria and their use in livestock |
| RU2009149164A (ru) * | 2007-06-08 | 2011-07-20 | Идемицу Козан Ко., Лтд. (JP) | Средство для повышения ферментации в рубце |
| ES2559842T3 (es) * | 2008-07-21 | 2016-02-16 | Erber Aktiengesellschaft | Procedimiento para el tratamiento de ensilaje forrajero para rumiantes, así como aditivo para el ensilaje forrajero |
| WO2010071222A1 (ja) * | 2008-12-20 | 2010-06-24 | 味の素株式会社 | 反芻動物用メタン生成抑制剤および飼料組成物 |
| WO2010072584A1 (en) * | 2008-12-23 | 2010-07-01 | Dsm Ip Assets B.V. | Bile acids in feed for reducing methane production emanating from the digestive activities of ruminants |
| FR2957754B1 (fr) | 2010-03-26 | 2012-04-27 | Inst Nat De La Rech Agronomique Inra | Utilisation d'un produit de fermentation fongique comme complement alimentaire |
| AU2011256017B2 (en) * | 2010-05-18 | 2013-11-28 | Able Corporation | Method for inhibition of methane production |
| CN102250806B (zh) * | 2011-07-01 | 2013-10-30 | 安徽农业大学 | 从植物源材料中筛选产细菌素乳酸菌的方法 |
| CN103829088B (zh) * | 2014-02-20 | 2016-03-16 | 江西省农业科学院畜牧兽医研究所 | 一种降低反刍动物甲烷产量、提高饲料利用效率的中草药饲料添加剂及其制备方法 |
| CN105285096B (zh) * | 2015-08-27 | 2019-01-29 | 光明乳业股份有限公司 | 一种富含果聚糖levan的发酵乳饮料及其制备方法 |
| CN109640687A (zh) * | 2016-06-29 | 2019-04-16 | 株式会社目立康 | 家畜用饲料效率改善剂、家畜用促增重饲料、家畜的饲养方法以及抑制甲烷产生的方法 |
| CN111690574B (zh) * | 2020-07-22 | 2021-05-25 | 云南省畜牧兽医科学院 | 一株类肠膜魏斯氏菌及其应用 |
| EP4391823A1 (en) * | 2021-08-23 | 2024-07-03 | International N&H Denmark ApS | Feed additive compositions and methods for using the same |
| DE202021107080U1 (de) | 2021-12-23 | 2022-02-08 | Sharad Phulari | Bakteriocin-Zusammensetzung von Lanthionin |
| US12084610B2 (en) | 2022-07-01 | 2024-09-10 | Arkea Bio Corp. | Compositions and methods for reducing deleterious atmospheric gas emissions from flooded ecosystems |
| CN116836860B (zh) * | 2023-06-28 | 2024-09-17 | 云南大学 | 泰国魏斯氏菌baz54菌株及其在降解生物胺中的应用 |
| CN117413892A (zh) * | 2023-10-31 | 2024-01-19 | 广东省农业科学院动物科学研究所 | 一种反刍动物用发酵饲料及其制备方法 |
| CN117814379A (zh) * | 2024-01-30 | 2024-04-05 | 兰州大学 | 一种青贮饲料的发酵方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7022684B2 (en) * | 2000-05-24 | 2006-04-04 | Pfizer Inc. | Treatment of rumen acidosis with α-amylase inhibitors |
| DE10110431A1 (de) * | 2001-03-05 | 2002-09-19 | Nutrinova Gmbh | Bacteriocinhaltiges Sorbinsäurepräparat als Futtermittelzusatz in der Nutztieraufzucht |
| ATE507882T1 (de) * | 2003-04-01 | 2011-05-15 | Avip S R L | Verwendung von bacteriocin zur verbesserung der verdauungsfunktion |
| US7112323B2 (en) * | 2003-05-07 | 2006-09-26 | Kraft Foods Holdings, Inc. | Intracellular proteinacious antimicrobial agents from lactic acid bacteria derived from fermented food samples |
-
2004
- 2004-12-17 JP JP2004366914A patent/JP2006166853A/ja not_active Withdrawn
-
2005
- 2005-12-16 EP EP05027599A patent/EP1673983A1/en not_active Withdrawn
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