JP2006068018A5 - - Google Patents

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Publication number
JP2006068018A5
JP2006068018A5 JP2005274803A JP2005274803A JP2006068018A5 JP 2006068018 A5 JP2006068018 A5 JP 2006068018A5 JP 2005274803 A JP2005274803 A JP 2005274803A JP 2005274803 A JP2005274803 A JP 2005274803A JP 2006068018 A5 JP2006068018 A5 JP 2006068018A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2005274803A
Other languages
Japanese (ja)
Other versions
JP2006068018A (ja
Filing date
Publication date
Priority claimed from US07/483,913 external-priority patent/US5171574A/en
Application filed filed Critical
Publication of JP2006068018A publication Critical patent/JP2006068018A/ja
Publication of JP2006068018A5 publication Critical patent/JP2006068018A5/ja
Withdrawn legal-status Critical Current

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JP2005274803A 1989-10-17 2005-09-21 骨形成具 Withdrawn JP2006068018A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42269989A 1989-10-17 1989-10-17
US07/483,913 US5171574A (en) 1989-02-23 1990-02-22 Bone collagen matrix for implants
US56992090A 1990-08-20 1990-08-20

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2003348890A Division JP2004041236A (ja) 1989-10-17 2003-10-07 骨形成具

Publications (2)

Publication Number Publication Date
JP2006068018A JP2006068018A (ja) 2006-03-16
JP2006068018A5 true JP2006068018A5 (enExample) 2006-07-27

Family

ID=27411374

Family Applications (6)

Application Number Title Priority Date Filing Date
JP2515578A Expired - Lifetime JP2845346B2 (ja) 1989-10-17 1990-10-15 骨形成具
JP9177440A Withdrawn JPH10114673A (ja) 1989-10-17 1997-07-02 骨形成具
JP2000254562A Expired - Lifetime JP3368260B2 (ja) 1989-10-17 2000-08-24 骨形成具
JP2002008070A Withdrawn JP2002281976A (ja) 1989-10-17 2002-01-16 骨形成具
JP2003348890A Withdrawn JP2004041236A (ja) 1989-10-17 2003-10-07 骨形成具
JP2005274803A Withdrawn JP2006068018A (ja) 1989-10-17 2005-09-21 骨形成具

Family Applications Before (5)

Application Number Title Priority Date Filing Date
JP2515578A Expired - Lifetime JP2845346B2 (ja) 1989-10-17 1990-10-15 骨形成具
JP9177440A Withdrawn JPH10114673A (ja) 1989-10-17 1997-07-02 骨形成具
JP2000254562A Expired - Lifetime JP3368260B2 (ja) 1989-10-17 2000-08-24 骨形成具
JP2002008070A Withdrawn JP2002281976A (ja) 1989-10-17 2002-01-16 骨形成具
JP2003348890A Withdrawn JP2004041236A (ja) 1989-10-17 2003-10-07 骨形成具

Country Status (11)

Country Link
EP (1) EP0448704B1 (enExample)
JP (6) JP2845346B2 (enExample)
AT (1) ATE167486T1 (enExample)
CA (1) CA2042577A1 (enExample)
DE (1) DE69032424T2 (enExample)
DK (1) DK0448704T3 (enExample)
ES (1) ES2118723T3 (enExample)
GR (1) GR3027722T3 (enExample)
LU (1) LU90855I2 (enExample)
NL (1) NL300062I2 (enExample)
WO (1) WO1991005802A1 (enExample)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5187076A (en) * 1986-07-01 1993-02-16 Genetics Institute, Inc. DNA sequences encoding BMP-6 proteins
US5013649A (en) * 1986-07-01 1991-05-07 Genetics Institute, Inc. DNA sequences encoding osteoinductive products
US6432919B1 (en) 1986-07-01 2002-08-13 Genetics Institute, Inc. Bone morphogenetic protein-3 and compositions
US5939388A (en) * 1986-07-01 1999-08-17 Rosen; Vicki A. Methods of administering BMP-5 compositions
US6150328A (en) * 1986-07-01 2000-11-21 Genetics Institute, Inc. BMP products
US5366875A (en) * 1986-07-01 1994-11-22 Genetics Institute, Inc. Methods for producing BMP-7 proteins
US5459047A (en) * 1986-07-01 1995-10-17 Genetics Institute, Inc. BMP-6 proteins
US5543394A (en) * 1986-07-01 1996-08-06 Genetics Institute, Inc. Bone morphogenetic protein 5(BMP-5) compositions
US5344654A (en) * 1988-04-08 1994-09-06 Stryker Corporation Prosthetic devices having enhanced osteogenic properties
US5284756A (en) * 1988-10-11 1994-02-08 Lynn Grinna Heterodimeric osteogenic factor
DK0429570T3 (da) * 1989-03-28 1998-04-27 Genetics Inst Osteoinducerende præparater
US5688678A (en) * 1990-05-16 1997-11-18 Genetics Institute, Inc. DNA encoding and methods for producing BMP-8 proteins
US7378392B1 (en) 1990-05-16 2008-05-27 Genetics Institute, Llc Bone and cartilage inductive proteins
US6090776A (en) * 1991-03-11 2000-07-18 Creative Bio Molecules, Inc. Morphogen treatment of organ implants
US6194376B1 (en) 1991-03-11 2001-02-27 Creative Biomolecules, Inc. Method for modulating inflammatory response comprising administering morphogen
US6395883B1 (en) 1991-03-11 2002-05-28 Curis, Inc. Soluble morphogenic protein complex compositions of matter
EP0575555B1 (en) * 1991-03-11 2001-07-18 Curis, Inc. Protein-induced morphogenesis
US6399569B1 (en) 1991-03-11 2002-06-04 Curis, Inc. Morphogen treatments for limiting proliferation of epithelial cells
US6077823A (en) * 1991-03-11 2000-06-20 Creative Biomolecules, Inc. Method for reducing tissue damage associated with ischemia-reperfusion or hypoxia injury
CA2104678C (en) 1991-03-11 2002-05-14 Charles M. Cohen Protein-induced morphogenesis
US7056882B2 (en) 1991-03-11 2006-06-06 Curis, Inc. Treatment to prevent loss of and/or increase bone mass in metabolic bone diseases
US5674844A (en) * 1991-03-11 1997-10-07 Creative Biomolecules, Inc. Treatment to prevent loss of and/or increase bone mass in metabolic bone diseases
DK0592562T3 (da) * 1991-06-25 1999-08-30 Genetics Inst BMP-9-præparater
US6287816B1 (en) 1991-06-25 2001-09-11 Genetics Institute, Inc. BMP-9 compositions
ATE308336T1 (de) * 1991-08-30 2005-11-15 Curis Inc Osteogenische proteine in der behandlung von metabolischen knochenkrankheiten
EP0601106B2 (en) * 1991-08-30 2003-11-05 Curis, Inc. Morphogen-induced modulation of inflammatory response
US5171579A (en) * 1991-10-11 1992-12-15 Genetics Institute, Inc. Formulations of blood clot-polymer matrix for delivery of osteogenic proteins
AU674500B2 (en) * 1991-11-04 1997-01-02 Genetics Institute, Llc Recombinant bone morphogenetic protein heterodimers, compositions and methods of use
IT1259042B (it) * 1992-01-27 1996-03-11 Mini Ricerca Scient Tecnolog Preparazione di vettori di espressione per la sintesi del polipeptide chiamato fattore osteogenetico op-1 in cellule eucariotiche di spodoptera frugiperda via infezione con baculovirus ricombinante
DK0625989T3 (da) * 1992-02-12 2000-06-26 Bioph Biotech Entw Pharm Gmbh DNA-sekvenser kodende for hidtil ukendte vækst-/differentieringsfaktorer
US6764994B1 (en) 1993-08-10 2004-07-20 Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mbh Growth/differential factor of the TGF-B family
IL110589A0 (en) * 1993-08-10 1994-11-11 Bioph Biotech Entw Pharm Gmbh Growth/differentiation factor of the TGF- beta family
US6291206B1 (en) 1993-09-17 2001-09-18 Genetics Institute, Inc. BMP receptor proteins
US5631159A (en) * 1993-09-22 1997-05-20 Creative Biomolecules, Inc. Lipid-modified serum free media
DE69434651T2 (de) 1993-12-07 2007-03-08 Genetics Institute, Inc., Cambridge Bmp-12, bmp-13 und diese enthaltende sehne-induzierende zusammensetzungen
EP0756628B1 (en) 1994-04-29 2007-11-14 Curis, Inc. Morphogenic protein-specific cell surface receptors and uses therefor
US5906827A (en) * 1994-06-03 1999-05-25 Creative Biomolecules, Inc. Matrix for the manufacture of autogenous replacement body parts
US6040431A (en) * 1995-06-07 2000-03-21 Stryker Corporation Single chain analogs of the TGF-β superfamily (morphons)
EP0904093A4 (en) 1996-03-22 2004-11-17 Gen Hospital Corp THE ADMINISTRATION OF GROWTH FACTOR POLYPEPTIDES AFTER AN ISCHEMICAL OF THE CENTRAL NERVOUS SYSTEM OR A TRAUMA
US6492508B1 (en) 1996-06-03 2002-12-10 United States Surgical Corp. A Division Of Tyco Healthcare Group Nucleic acids encoding extracellular matrix proteins
DE19647853A1 (de) 1996-11-19 1998-05-20 Bioph Biotech Entw Pharm Gmbh Verbindungen mit verbesserter knorpel- und/oder knocheninduzierender Aktivität
US6034062A (en) * 1997-03-13 2000-03-07 Genetics Institute, Inc. Bone morphogenetic protein (BMP)-9 compositions and their uses
WO1998054572A1 (en) * 1997-05-30 1998-12-03 Creative Biomolecules, Inc. Methods for evaluating tissue morphogenesis and activity
EP1037910A2 (en) * 1997-12-04 2000-09-27 Curis, Inc. Maintenance of smooth muscle integrity by morphogenic proteins
CA2345024C (en) 1998-10-07 2009-05-19 Stryker Corporation Modified tgf-.beta. superfamily proteins
US6846906B1 (en) 1998-10-07 2005-01-25 Stryker Corporation Modified proteins of the TGF-β superfamily, including morphogenic proteins
US6677432B1 (en) 1998-10-07 2004-01-13 Stryker Corporation Mutations of the C-terminal portion of TGF-β superfamily proteins
US6663870B2 (en) 1998-12-07 2003-12-16 Zymogenetics, Inc. Methods for promoting growth of bone using zvegf3
US6727224B1 (en) 1999-02-01 2004-04-27 Genetics Institute, Llc. Methods and compositions for healing and repair of articular cartilage
DE19906096A1 (de) 1999-02-13 2000-08-17 Walter Sebald Protein mit einem Heparin-bindenden Epitop
US6468543B1 (en) 1999-05-03 2002-10-22 Zymogenetics, Inc. Methods for promoting growth of bone using ZVEGF4
ATE271886T1 (de) 1999-10-15 2004-08-15 Inst Genetics Llc Hyaluronsäure enthaltende zusammensetzungen zur abgabe osteogener proteine
AU2000251259A1 (en) * 2000-02-04 2001-08-14 Zymogenetics Inc. Methods for promoting growth of bone, ligament, and cartilage using zvegf4
CA2449008A1 (en) 2001-06-01 2002-12-12 Wyeth Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins
TWI267378B (en) 2001-06-08 2006-12-01 Wyeth Corp Calcium phosphate delivery vehicles for osteoinductive proteins
JP4338516B2 (ja) 2001-10-02 2009-10-07 清史 軒原 血管新生剤
ES2247423T5 (es) 2001-11-19 2015-12-30 Scil Technology Gmbh Método de producción de un dispositivo recubierto homogéneamente que tiene propiedades osteoinductoras y osteoconductoras
PT1539261E (pt) 2002-09-10 2006-08-31 Scil Technology Gmbh Implante metalico revestido sob concentracao reduzida de oxigenio com proteina osteoindutiva
US7163920B2 (en) 2003-09-30 2007-01-16 Ethicon, Inc. Peptide with osteogenic activity
ATE478008T1 (de) 2004-03-10 2010-09-15 Scil Technology Gmbh Überzogene implantate, ihre herstellung und verwendung davon
CA2563374A1 (en) 2004-04-27 2005-12-08 Research Development Foundation Antagonism of tgf-.beta.superfamily receptor signaling
DE102008036576A1 (de) * 2008-07-31 2010-02-04 Gelita Ag Partikel aus Kollagenmaterial und Verfahren zur Herstellung
US8952130B2 (en) 2009-02-24 2015-02-10 The Salk Institute For Biological Studies Designer ligands of TGF-β superfamily
US20110002897A1 (en) 2009-06-11 2011-01-06 Burnham Institute For Medical Research Directed differentiation of stem cells

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4172128A (en) * 1975-03-26 1979-10-23 Erhard Thiele Process of degrading and regenerating bone and tooth material and products
US4294753A (en) * 1980-08-04 1981-10-13 The Regents Of The University Of California Bone morphogenetic protein process
US4394370A (en) * 1981-09-21 1983-07-19 Jefferies Steven R Bone graft material for osseous defects and method of making same
US4434094A (en) * 1983-04-12 1984-02-28 Collagen Corporation Partially purified osteogenic factor and process for preparing same from demineralized bone
CA1229789A (en) * 1983-06-06 1987-12-01 David Baylink Polypeptides exhibiting skeletal growth factor activity
US4795804A (en) * 1983-08-16 1989-01-03 The Regents Of The University Of California Bone morphogenetic agents
NZ210699A (en) * 1984-01-04 1989-06-28 Int Genetic Eng Isolation of an osteogenic protein of the p3 immunologically related family
US4563489A (en) * 1984-02-10 1986-01-07 University Of California Biodegradable organic polymer delivery system for bone morphogenetic protein
CA1295796C (en) * 1984-03-27 1992-02-18 Conrad Whyne Biodegradable matrix and methods for producing same
US4837285A (en) * 1984-03-27 1989-06-06 Medimatrix Collagen matrix beads for soft tissue repair
US4620327A (en) * 1984-07-05 1986-11-04 Caplan Arnold I Process of adapting soluble bone protein for use in stimulating osteoinduction
US4789663A (en) * 1984-07-06 1988-12-06 Collagen Corporation Methods of bone repair using collagen
DE3588058T3 (de) * 1984-07-16 2005-04-07 Celtrix Pharmaceuticals, Inc., Palo Alto Knorpel-induzierende Polypeptid-Faktoren aus Knochen
EP0169001A3 (en) * 1984-07-17 1987-11-25 Collagen Corporation Collagen coated bone implants
US4657548A (en) * 1984-09-11 1987-04-14 Helitrex, Inc. Delivery system for implantation of fine particles in surgical procedures
US4888366A (en) * 1984-10-24 1989-12-19 Collagen Corporation Inductive collagen-based bone repair preparations
US4563350A (en) * 1984-10-24 1986-01-07 Collagen Corporation Inductive collagen based bone repair preparations
US4600533A (en) * 1984-12-24 1986-07-15 Collagen Corporation Collagen membranes for medical use
EP0230647B1 (en) * 1985-12-27 1993-03-31 Sumitomo Pharmaceuticals Company, Limited Method for producing a sustained release formulation
IL83003A (en) * 1986-07-01 1995-07-31 Genetics Inst Osteoinductive factors
US4824939A (en) * 1986-10-09 1989-04-25 Eastman Kodak Company Process for leaching particulate solid materials
IT1214505B (it) * 1987-03-12 1990-01-18 Gentili Ist Spa Procedimento per la preparazione di collageno e prodotti cosi'ottenuto.
JPS6434371A (en) * 1987-07-31 1989-02-03 Nitta Gelatin Kk Periosteal bone forming material
US4812120A (en) * 1987-11-02 1989-03-14 Flanagan Dennis F Implantable percutaneous device
JPH04505607A (ja) * 1988-04-06 1992-10-01 セルトリックス ファーマシューティカルズ インコーポレイテッド 骨誘導タンパク
EP0408649A4 (en) * 1988-04-08 1991-11-27 Genetics Institute, Inc. Bone and cartilage inductive compositions
ATE142644T1 (de) * 1988-04-08 1996-09-15 Stryker Corp Biosynthetische osteogene proteine und sie enthaltende osteogene vorrichtungen
DK0429570T3 (da) * 1989-03-28 1998-04-27 Genetics Inst Osteoinducerende præparater

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