JP2006020648A5 - - Google Patents
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- JP2006020648A5 JP2006020648A5 JP2005271209A JP2005271209A JP2006020648A5 JP 2006020648 A5 JP2006020648 A5 JP 2006020648A5 JP 2005271209 A JP2005271209 A JP 2005271209A JP 2005271209 A JP2005271209 A JP 2005271209A JP 2006020648 A5 JP2006020648 A5 JP 2006020648A5
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- JP
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- Prior art keywords
- trt
- polypeptide
- antigen
- leukocytes
- consecutive amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 108090000765 processed proteins & peptides Proteins 0.000 claims 12
- 229920001184 polypeptide Polymers 0.000 claims 11
- 102000004196 processed proteins & peptides Human genes 0.000 claims 11
- 102000004163 DNA-directed RNA polymerases Human genes 0.000 claims 8
- 108090000626 DNA-directed RNA polymerases Proteins 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 6
- 210000000612 antigen-presenting cell Anatomy 0.000 claims 5
- 210000000265 leukocyte Anatomy 0.000 claims 3
- 101000655352 Homo sapiens Telomerase reverse transcriptase Proteins 0.000 claims 2
- 125000000539 amino acid group Chemical group 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 claims 2
- 230000002163 immunogen Effects 0.000 claims 2
- 102000043129 MHC class I family Human genes 0.000 claims 1
- 108091054437 MHC class I family Proteins 0.000 claims 1
- 102000043131 MHC class II family Human genes 0.000 claims 1
- 108091054438 MHC class II family Proteins 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 210000001744 T-lymphocyte Anatomy 0.000 claims 1
- 108010017842 Telomerase Proteins 0.000 claims 1
- 102100032938 Telomerase reverse transcriptase Human genes 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 210000004443 dendritic cell Anatomy 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 210000002433 mononuclear leukocyte Anatomy 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 210000005259 peripheral blood Anatomy 0.000 claims 1
- 239000011886 peripheral blood Substances 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11200698P | 1998-03-31 | 1998-03-31 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000541280A Division JP2002509716A (ja) | 1998-03-31 | 1999-03-30 | テロメラーゼ抗原に対する免疫応答を惹起するための方法および組成物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006353532A Division JP2007137889A (ja) | 1998-03-31 | 2006-12-27 | テロメラーゼ抗原に対する免疫応答を惹起するための方法および組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006020648A JP2006020648A (ja) | 2006-01-26 |
| JP2006020648A5 true JP2006020648A5 (https=) | 2007-02-15 |
Family
ID=22341634
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000541280A Withdrawn JP2002509716A (ja) | 1998-03-31 | 1999-03-30 | テロメラーゼ抗原に対する免疫応答を惹起するための方法および組成物 |
| JP2005271209A Withdrawn JP2006020648A (ja) | 1998-03-31 | 2005-09-16 | テロメラーゼ抗原に対する免疫応答を惹起するための方法および組成物 |
| JP2006353532A Pending JP2007137889A (ja) | 1998-03-31 | 2006-12-27 | テロメラーゼ抗原に対する免疫応答を惹起するための方法および組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000541280A Withdrawn JP2002509716A (ja) | 1998-03-31 | 1999-03-30 | テロメラーゼ抗原に対する免疫応答を惹起するための方法および組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006353532A Pending JP2007137889A (ja) | 1998-03-31 | 2006-12-27 | テロメラーゼ抗原に対する免疫応答を惹起するための方法および組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6440735B1 (https=) |
| EP (1) | EP1068296B1 (https=) |
| JP (3) | JP2002509716A (https=) |
| AU (1) | AU3456099A (https=) |
| CA (1) | CA2347067C (https=) |
| WO (1) | WO1999050392A1 (https=) |
Families Citing this family (63)
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| US6444650B1 (en) * | 1996-10-01 | 2002-09-03 | Geron Corporation | Antisense compositions for detecting and inhibiting telomerase reverse transcriptase |
| US6808880B2 (en) * | 1996-10-01 | 2004-10-26 | Geron Corporation | Method for detecting polynucleotides encoding telomerase |
| IL129222A0 (en) | 1996-10-01 | 2000-02-17 | Geron Corp | Telomerase reverse transcriptase |
| US6093809A (en) * | 1996-10-01 | 2000-07-25 | University Technology Corporation | Telomerase |
| US7585622B1 (en) | 1996-10-01 | 2009-09-08 | Geron Corporation | Increasing the proliferative capacity of cells using telomerase reverse transcriptase |
| US6261836B1 (en) * | 1996-10-01 | 2001-07-17 | Geron Corporation | Telomerase |
| US6475789B1 (en) * | 1996-10-01 | 2002-11-05 | University Technology Corporation | Human telomerase catalytic subunit: diagnostic and therapeutic methods |
| US7413864B2 (en) * | 1997-04-18 | 2008-08-19 | Geron Corporation | Treating cancer using a telomerase vaccine |
| US20050013825A1 (en) * | 1997-04-18 | 2005-01-20 | Geron Corporation | Vaccine containing the catalytic subunit of telomerase for treating cancer |
| US7622549B2 (en) * | 1997-04-18 | 2009-11-24 | Geron Corporation | Human telomerase reverse transcriptase polypeptides |
| EP1068296B1 (en) | 1998-03-31 | 2011-08-10 | Geron Corporation | Compositions for eliciting an immune response to a telomerase antigen |
| US6337200B1 (en) * | 1998-03-31 | 2002-01-08 | Geron Corporation | Human telomerase catalytic subunit variants |
| US7402307B2 (en) | 1998-03-31 | 2008-07-22 | Geron Corporation | Method for identifying and killing cancer cells |
| US7030211B1 (en) | 1998-07-08 | 2006-04-18 | Gemvax As | Antigenic peptides derived from telomerase |
| US20020142974A1 (en) * | 1998-09-11 | 2002-10-03 | Leonard D. Kohn | Immune activation by double-stranded polynucleotides |
| US7851591B1 (en) | 1998-10-29 | 2010-12-14 | Dana Farber Cancer Institute, Inc. | Cancer immunotherapy and diagnosis using universal tumor associated antigens, including hTERT |
| CA2368967A1 (en) * | 1999-04-09 | 2000-10-19 | Biomira, Inc. | Telomerase-specific cancer vaccine |
| EP1257284A4 (en) * | 2000-02-15 | 2005-12-21 | Univ California | UNIVERSAL VACCINE AND METHOD OF TREATING CANCER USING TELOMERASE REVERSE TRANSCRIPTASE |
| JP2004527449A (ja) | 2000-02-15 | 2004-09-09 | リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | テロメラーゼ逆転写酵素を用いる癌を治療するための万能ワクチンと方法 |
| GB0031430D0 (en) * | 2000-12-22 | 2001-02-07 | Norsk Hydro As | Polypeptides |
| KR101192652B1 (ko) * | 2003-02-06 | 2012-10-19 | 앤저 테라퓨틱스 인코퍼레이티드 | 비포식 세포로의 침투가 약화된 리스테리아, 리스테리아를 포함하는 백신, 및 그것의 사용방법 |
| KR101173871B1 (ko) * | 2003-02-06 | 2012-08-16 | 앤저 테라퓨틱스 인코퍼레이티드 | 변형된 독립생존 미생물, 백신 조성물 및 그것의 사용방법 |
| US7695725B2 (en) * | 2003-02-06 | 2010-04-13 | Aduro Biotech | Modified free-living microbes, vaccine compositions and methods of use thereof |
| US7842289B2 (en) * | 2003-12-24 | 2010-11-30 | Aduro Biotech | Recombinant nucleic acid molecules, expression cassettes, and bacteria, and methods of use thereof |
| CA2574802A1 (en) | 2004-07-20 | 2006-02-02 | Isogenis, Inc. | Specific inhibition of autoimmunity and diseases associated with autoantigens |
| CA2504451A1 (en) * | 2004-08-10 | 2006-02-10 | Geron Corporation | Dendritic cell vaccines for treating cancer made from embryonic stem cells |
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| US20090196850A1 (en) | 2005-01-06 | 2009-08-06 | Novo Nordisk A/S | Anti-Kir Combination Treatments and Methods |
| JP5225069B2 (ja) | 2005-03-23 | 2013-07-03 | ゲンマブ エー／エス | 多発性骨髄腫の治療のためのｃｄ３８に対する抗体 |
| EP1748067A1 (en) * | 2005-07-29 | 2007-01-31 | Institut Pasteur | Polynucleotides encoding MHC class I-restricted hTERT epitopes, analogues thereof or polyepitopes |
| RU2309753C1 (ru) * | 2006-05-05 | 2007-11-10 | ЗАО "РеМеТэкс" | Комбинированный клеточный трансплантат на основе лимфокинактивированных киллеров и дендритных клеток, способ его получения и способ лечения и профилактики онкологических, инфекционных заболеваний и иммунодефицитных состояний |
| WO2008037257A2 (en) | 2006-09-26 | 2008-04-03 | Genmab A/S | Anti-cd38 plus corticosteroids plus a non-corticosteroid chemotherapeutic for treating tumors |
| UA109633C2 (uk) | 2008-12-09 | 2015-09-25 | Антитіло людини проти тканинного фактора | |
| US8858952B2 (en) | 2009-02-19 | 2014-10-14 | Mayo Foundation For Medical Education And Research | Methods and materials for generating T cells |
| US8563307B2 (en) | 2009-02-24 | 2013-10-22 | James Wang | Treatment of immunosuppression-related disorders |
| PL2536830T3 (pl) | 2010-02-16 | 2020-02-28 | Ultimovacs As | Polipeptydy |
| PT3904391T (pt) | 2010-03-10 | 2024-10-14 | Genmab As | Anticorpos monoclonais contra c-met |
| CA2800769C (en) | 2010-05-27 | 2021-11-02 | Genmab A/S | Monoclonal antibodies against her2 epitope |
| EP2576621B1 (en) | 2010-05-27 | 2019-04-10 | Genmab A/S | Monoclonal antibodies against her2 |
| SMT202000031T1 (it) | 2010-06-09 | 2020-03-13 | Genmab As | Anticorpi contro cd38 umano |
| BR112012031727B1 (pt) | 2010-06-15 | 2022-03-29 | Genmab A/S | Conjugado de droga-anticorpo, composição farmacêutica, e, uso do conjugado de droga- anticorpo |
| US8679474B2 (en) | 2010-08-04 | 2014-03-25 | StemBios Technologies, Inc. | Somatic stem cells |
| AU2012245116A1 (en) | 2011-04-20 | 2013-11-07 | Genmab A/S | Bispecific antibodies against HER2 and CD3 |
| EP4520771A3 (en) | 2011-04-20 | 2025-07-16 | Genmab A/S | Bispecifc antibodies against her2 |
| CN103796678B (zh) | 2011-04-20 | 2018-02-27 | 健玛保 | 针对her2的双特异性抗体 |
| TWI614340B (zh) | 2011-09-28 | 2018-02-11 | 幹細胞生物科技股份有限公司 | 體幹細胞及其製備方法 |
| TWI687519B (zh) | 2012-12-06 | 2020-03-11 | 美商幹細胞生物科技股份有限公司 | Ｌｇｒ５＋體幹細胞 |
| EP2746769A1 (en) | 2012-12-21 | 2014-06-25 | Stembios Technologies, Inc. | Method for evaluating effect of action on subject based on stem celldynamics |
| WO2016089610A1 (en) | 2014-12-06 | 2016-06-09 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Bispecific antibody for cancer immunotherapy |
| US10544220B2 (en) | 2015-01-08 | 2020-01-28 | Genmab A/S | Bispecific antibodies against CD3 and CD20 |
| US11020465B2 (en) | 2016-03-04 | 2021-06-01 | The Trustees Of Columbia University In The City Of New York | Development of dual whole cell-based vaccine against pancreatic cancer |
| AU2017305396A1 (en) * | 2016-08-02 | 2019-02-21 | Nant Holdings Ip, Llc | Transfection of dendritic cells and methods therefor |
| EP3518955A4 (en) * | 2016-09-30 | 2020-10-07 | The Wistar Institute Of Anatomy And Biology | TERT-IMMUNOGENIC COMPOSITIONS AND METHODS OF TREATMENT THEREOF |
| EP3585403A4 (en) | 2017-02-22 | 2020-12-09 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | CHEMERICAL ANTIGENIC RECEPTORS BINDING TO TIM3 |
| KR20200027508A (ko) | 2017-07-07 | 2020-03-12 | 에이치 리 모피트 캔서 센터 앤드 리서어치 인스티튜트 아이엔씨 | 돌연변이된 cd28 공동자극 도메인을 갖는 키메라 항원 수용체 |
| BR112020013910A2 (pt) | 2018-01-08 | 2020-12-01 | H. Lee Moffitt Cancer Center And Research Institute Inc. | composições e métodos para alvejamento de cânceres que expressam cd99 |
| MX2020007338A (es) | 2018-01-09 | 2020-11-06 | H Lee Moffitt Cancer Ct & Res | Composiciones y métodos para el direccionamiento a tipos de cáncer que expresan clec12a. |
| WO2020023361A1 (en) | 2018-07-23 | 2020-01-30 | H. Lee Moffitt Cancer Center And Research Institute Inc. | Enhancing anti-tumor response in melanoma cells with defective sting signaling |
| WO2021113212A1 (en) | 2019-12-02 | 2021-06-10 | Celgene Corporation | Therapy for the treatment of cancer |
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| EP4687959A1 (en) | 2023-03-24 | 2026-02-11 | Cornell University | Utilizing t cells derived from tumor draining lymph nodes for chimeric antigen receptor (car) t cell therapy for the treatment of cancer |
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| AU1220599A (en) | 1997-11-14 | 1999-06-07 | Hemosol Inc. | Method for the production and use of dendritic cells |
| EP1068296B1 (en) | 1998-03-31 | 2011-08-10 | Geron Corporation | Compositions for eliciting an immune response to a telomerase antigen |
| WO1999051255A1 (en) | 1998-04-06 | 1999-10-14 | The Johns Hopkins University School Of Medicine | Telomerase-associated proteins |
| WO1999063050A2 (en) | 1998-06-02 | 1999-12-09 | Dendreon Corporation | Method for preparation and in vivo administration of antigen presenting cell composition |
| US6277613B1 (en) | 1998-06-10 | 2001-08-21 | The Rockefeller University | TRF1 binding protein, methods of use thereof |
| WO1999063945A2 (en) | 1998-06-12 | 1999-12-16 | Sloan-Kettering Institute For Cancer Research | Vaccination strategy to prevent and treat cancers |
| US7030211B1 (en) | 1998-07-08 | 2006-04-18 | Gemvax As | Antigenic peptides derived from telomerase |
| GB9816781D0 (en) | 1998-07-31 | 1998-09-30 | Univ London | Herpes virus vectors for dendritic cells |
| CA2343355A1 (en) | 1998-09-15 | 2000-03-23 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | In situ injection of antigen-presenting cells with genetically enhanced cytokine expression |
| US7851591B1 (en) | 1998-10-29 | 2010-12-14 | Dana Farber Cancer Institute, Inc. | Cancer immunotherapy and diagnosis using universal tumor associated antigens, including hTERT |
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-
1999
- 1999-03-30 EP EP99916193A patent/EP1068296B1/en not_active Expired - Lifetime
- 1999-03-30 CA CA2347067A patent/CA2347067C/en not_active Expired - Lifetime
- 1999-03-30 WO PCT/US1999/006898 patent/WO1999050392A1/en not_active Ceased
- 1999-03-30 AU AU34560/99A patent/AU3456099A/en not_active Abandoned
- 1999-03-30 JP JP2000541280A patent/JP2002509716A/ja not_active Withdrawn
-
2000
- 2000-09-29 US US09/675,321 patent/US6440735B1/en not_active Expired - Lifetime
-
2005
- 2005-09-16 JP JP2005271209A patent/JP2006020648A/ja not_active Withdrawn
-
2006
- 2006-12-27 JP JP2006353532A patent/JP2007137889A/ja active Pending
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