JP2005538701A5 - - Google Patents
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- JP2005538701A5 JP2005538701A5 JP2004502947A JP2004502947A JP2005538701A5 JP 2005538701 A5 JP2005538701 A5 JP 2005538701A5 JP 2004502947 A JP2004502947 A JP 2004502947A JP 2004502947 A JP2004502947 A JP 2004502947A JP 2005538701 A5 JP2005538701 A5 JP 2005538701A5
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- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
- cdr2
- cdr3
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37932202P | 2002-05-10 | 2002-05-10 | |
| US41821302P | 2002-10-14 | 2002-10-14 | |
| US46050703P | 2003-04-03 | 2003-04-03 | |
| PCT/US2003/015044 WO2003094859A2 (en) | 2002-05-10 | 2003-05-12 | Epha2 monoclonal antibodies and methods of use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010115398A Division JP2010246546A (ja) | 2002-05-10 | 2010-05-19 | EphA2モノクローナル抗体およびその使用法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005538701A JP2005538701A (ja) | 2005-12-22 |
| JP2005538701A5 true JP2005538701A5 (enExample) | 2008-07-03 |
| JP4557714B2 JP4557714B2 (ja) | 2010-10-06 |
Family
ID=29424523
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004502947A Expired - Fee Related JP4557714B2 (ja) | 2002-05-10 | 2003-05-12 | EphA2モノクローナル抗体およびその使用法 |
| JP2010115398A Pending JP2010246546A (ja) | 2002-05-10 | 2010-05-19 | EphA2モノクローナル抗体およびその使用法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010115398A Pending JP2010246546A (ja) | 2002-05-10 | 2010-05-19 | EphA2モノクローナル抗体およびその使用法 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20040028685A1 (enExample) |
| EP (1) | EP1519956B1 (enExample) |
| JP (2) | JP4557714B2 (enExample) |
| AT (1) | ATE525398T1 (enExample) |
| AU (2) | AU2003243228B2 (enExample) |
| CA (1) | CA2485373A1 (enExample) |
| ES (1) | ES2373715T3 (enExample) |
| WO (1) | WO2003094859A2 (enExample) |
Families Citing this family (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| US7192698B1 (en) | 1999-08-17 | 2007-03-20 | Purdue Research Foundation | EphA2 as a diagnostic target for metastatic cancer |
| US7101976B1 (en) | 2000-09-12 | 2006-09-05 | Purdue Research Foundation | EphA2 monoclonal antibodies and methods of making and using same |
| JP4557714B2 (ja) * | 2002-05-10 | 2010-10-06 | メディミューン,エルエルシー | EphA2モノクローナル抗体およびその使用法 |
| WO2004014292A2 (en) * | 2002-05-10 | 2004-02-19 | Purdue Research Foundation | EphA2 AGONISTIC MONOCLONAL ANTIBODIES AND METHODS OF USE THEREOF |
| US20050152899A1 (en) * | 2002-05-10 | 2005-07-14 | Kinch Michael S. | EphA2 agonistic monoclonal antibodies and methods of use thereof |
| AU2003239585B2 (en) * | 2002-05-23 | 2009-06-04 | Purdue Research Foundation | Low molecular weight protein tyrosine phosphatase (LMW-PTP) as diagnostic and therapeutic target |
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| CA2531069A1 (en) * | 2003-07-03 | 2005-01-27 | The Trustees Of The University Of Pennsylvania | Inhibition of syk kinase expression |
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| EP1732580A4 (en) * | 2003-12-24 | 2008-01-23 | Medimmune Inc | EPHA2 VACCINES |
| DE102004010050A1 (de) * | 2004-03-02 | 2005-09-22 | Bayer Healthcare Ag | Spezifische monoklonale und polyklonale Antikörper für Repinotan und dessen ringoffene Form |
| EP2287194B1 (en) | 2004-03-12 | 2016-10-26 | Vasgene Therapeutics, Inc. | Antibodies binding to EphB4 for inhibiting angiogenesis and tumor growth |
| DE602005025459D1 (de) | 2004-03-12 | 2011-02-03 | Vasgene Therapeutics Inc | Ephb4-bindende antikörper zur inhibierung von angiogenese und tumorwachstum |
| US20100009929A1 (en) | 2004-03-29 | 2010-01-14 | Cheng Jin Q | Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof |
| US20110008327A1 (en) | 2004-03-29 | 2011-01-13 | Cheng Jin Q | Compositions including triciribine and epidermal growth factor receptor inhibitor compounds or salts thereof and methods of use thereof |
| AU2005228410A1 (en) | 2004-03-29 | 2005-10-13 | University Of South Florida | Effective treatment of tumors and cancer with triciribine and related compounds |
| US20100173864A1 (en) * | 2004-03-29 | 2010-07-08 | Cheng Jin Q | Compositions including triciribine and one or more platinum compounds and methods of use thereof |
| US20100028339A1 (en) | 2004-03-29 | 2010-02-04 | Cheng Jin Q | Compositions including triciribine and trastuzumab and methods of use thereof |
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| CA2562771C (en) | 2004-04-12 | 2013-04-09 | Medimmune, Inc. | Anti-il-9 antibody formulations and uses thereof |
| US20060019342A1 (en) * | 2004-06-25 | 2006-01-26 | Medimmune, Inc. | Increasing the production of recombinant antibodies in mammalian cells by site-directed mutagenesis |
| CA2577370A1 (en) * | 2004-08-16 | 2006-03-02 | Medimmune, Inc. | Integrin antagonists with enhanced antibody dependent cell-mediated cytotoxicity activity |
| US20060204512A1 (en) | 2004-09-23 | 2006-09-14 | Vasgene Therapeutics, Inc. | Polypeptide compounds for inhibiting angiogenesis and tumor growth |
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| EA020324B1 (ru) | 2006-07-18 | 2014-10-30 | Санофи-Авентис | АНТИТЕЛА К РЕЦЕПТОРУ ЭФРИНА EphA2 И ИХ ПРИМЕНЕНИЕ |
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| DK2173378T3 (da) | 2007-06-27 | 2014-05-12 | Admune Therapeutics Llc | Komplekser af il-15 og il-15ralfa og anvendelser deraf |
| CA2696164C (en) | 2007-08-13 | 2018-06-12 | Vasgene Therapeutics, Inc. | Cancer treatment using humanized antibodies that bind to ephb4 |
| DK2199390T3 (en) * | 2007-08-30 | 2017-04-03 | Daiichi Sankyo Co Ltd | ANTI-EphA2 ANTIBODY |
| AU2010242914B2 (en) | 2009-04-29 | 2014-11-13 | Trellis Bioscience, Llc | Improved antibodies immunoreactive with heregulin-coupled HER3 |
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| UY32914A (es) | 2009-10-02 | 2011-04-29 | Sanofi Aventis | Anticuerpos que se usan específicamente al receptor epha2 |
| TR201804897T4 (tr) | 2009-10-07 | 2018-06-21 | Macrogenics Inc | Fukosi̇lasyon ölçüsünün deği̇şi̇mleri̇nden dolayi geli̇şmi̇ş efektör i̇şlevi̇ sergi̇leyen fc bölgesi̇ni̇ i̇çeren poli̇pepti̇tler ve bunlarin kullanimlarina yöneli̇k yöntemler |
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| AU2012216627A1 (en) * | 2011-11-14 | 2013-05-30 | Newcastle Innovation Ltd. | Composition and methods for the diagnosis, prognosis and treatment of leukemia |
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| SG10201913324PA (en) * | 2014-05-29 | 2020-03-30 | Macrogenics Inc | Tri-specific binding molecules and methods of use thereof |
| US10961311B2 (en) | 2016-04-15 | 2021-03-30 | Macrogenics, Inc. | B7-H3 binding molecules, antibody drug conjugates thereof and methods of use thereof |
| EP3572426A4 (en) * | 2017-01-23 | 2020-12-23 | Toyo University | ANTI-BODY ANTI-EPHA2 AND IMMUNOLOGICAL DETECTION OF EPHA2 CALLING ANTI-BODY AUDIT |
| BR112019017628A2 (pt) | 2017-02-24 | 2020-07-07 | Macrogenics, Inc. | molécula de ligação a cd137 x ta, composições farmacêuticas, uso da molécula de ligação a cd137 x ta, molécula de ligação a cd137, uso da molécula de ligação a cd137, molécula de ligação a her2/neu, uso da molécula de ligação a her2/neu, e uso de uma composição |
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| JP4557714B2 (ja) * | 2002-05-10 | 2010-10-06 | メディミューン,エルエルシー | EphA2モノクローナル抗体およびその使用法 |
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| US7504211B2 (en) * | 2002-08-27 | 2009-03-17 | Bristol-Myers Squibb Company | Methods of using EPHA2 for predicting activity of compounds that interact with and/or modulate protein tyrosine kinases and/or protein tyrosine kinase pathways in breast cells |
| AU2003268345A1 (en) * | 2002-09-24 | 2004-04-19 | The Burnham Institute | Novel agents that modulate eph receptor activity |
| EP1617864A4 (en) * | 2003-04-11 | 2006-06-21 | Medimmune Inc | EPHA2 AND NON-NEOPLASTIC HYPERPROLIFERATIVE CELL TROUBLESHOOTING |
| AU2004229527B2 (en) * | 2003-04-11 | 2009-08-20 | Medimmune, Llc | Methods of preventing or treating respiratory conditions |
| KR101224235B1 (ko) * | 2003-04-11 | 2013-01-25 | 메디뮨 엘엘씨 | 재조합 il9 항체 및 그의 용도 |
-
2003
- 2003-05-12 JP JP2004502947A patent/JP4557714B2/ja not_active Expired - Fee Related
- 2003-05-12 AU AU2003243228A patent/AU2003243228B2/en not_active Ceased
- 2003-05-12 ES ES03750125T patent/ES2373715T3/es not_active Expired - Lifetime
- 2003-05-12 US US10/436,782 patent/US20040028685A1/en not_active Abandoned
- 2003-05-12 AT AT03750125T patent/ATE525398T1/de not_active IP Right Cessation
- 2003-05-12 WO PCT/US2003/015044 patent/WO2003094859A2/en not_active Ceased
- 2003-05-12 CA CA002485373A patent/CA2485373A1/en not_active Abandoned
- 2003-05-12 EP EP03750125A patent/EP1519956B1/en not_active Expired - Lifetime
-
2007
- 2007-03-12 US US11/717,799 patent/US20070166314A1/en not_active Abandoned
-
2009
- 2009-06-25 AU AU2009202542A patent/AU2009202542A1/en not_active Abandoned
-
2010
- 2010-04-07 US US12/755,468 patent/US20100278838A1/en not_active Abandoned
- 2010-05-19 JP JP2010115398A patent/JP2010246546A/ja active Pending
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