JP2005538701A5 - - Google Patents
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- JP2005538701A5 JP2005538701A5 JP2004502947A JP2004502947A JP2005538701A5 JP 2005538701 A5 JP2005538701 A5 JP 2005538701A5 JP 2004502947 A JP2004502947 A JP 2004502947A JP 2004502947 A JP2004502947 A JP 2004502947A JP 2005538701 A5 JP2005538701 A5 JP 2005538701A5
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- Prior art keywords
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- amino acid
- acid sequence
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37932202P | 2002-05-10 | 2002-05-10 | |
| US41821302P | 2002-10-14 | 2002-10-14 | |
| US46050703P | 2003-04-03 | 2003-04-03 | |
| PCT/US2003/015044 WO2003094859A2 (en) | 2002-05-10 | 2003-05-12 | Epha2 monoclonal antibodies and methods of use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010115398A Division JP2010246546A (ja) | 2002-05-10 | 2010-05-19 | EphA2モノクローナル抗体およびその使用法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005538701A JP2005538701A (ja) | 2005-12-22 |
| JP2005538701A5 true JP2005538701A5 (enExample) | 2008-07-03 |
| JP4557714B2 JP4557714B2 (ja) | 2010-10-06 |
Family
ID=29424523
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004502947A Expired - Fee Related JP4557714B2 (ja) | 2002-05-10 | 2003-05-12 | EphA2モノクローナル抗体およびその使用法 |
| JP2010115398A Pending JP2010246546A (ja) | 2002-05-10 | 2010-05-19 | EphA2モノクローナル抗体およびその使用法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010115398A Pending JP2010246546A (ja) | 2002-05-10 | 2010-05-19 | EphA2モノクローナル抗体およびその使用法 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20040028685A1 (enExample) |
| EP (1) | EP1519956B1 (enExample) |
| JP (2) | JP4557714B2 (enExample) |
| AT (1) | ATE525398T1 (enExample) |
| AU (2) | AU2003243228B2 (enExample) |
| CA (1) | CA2485373A1 (enExample) |
| ES (1) | ES2373715T3 (enExample) |
| WO (1) | WO2003094859A2 (enExample) |
Families Citing this family (82)
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|---|---|---|---|---|
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| US7192698B1 (en) * | 1999-08-17 | 2007-03-20 | Purdue Research Foundation | EphA2 as a diagnostic target for metastatic cancer |
| US6927203B1 (en) | 1999-08-17 | 2005-08-09 | Purdue Research Foundation | Treatment of metastatic disease |
| US7101976B1 (en) | 2000-09-12 | 2006-09-05 | Purdue Research Foundation | EphA2 monoclonal antibodies and methods of making and using same |
| US20040028685A1 (en) * | 2002-05-10 | 2004-02-12 | Kinch Michael S. | EphA2 monoclonal antibodies and methods of use thereof |
| ES2377720T3 (es) * | 2002-05-10 | 2012-03-30 | Purdue Research Foundation | Anticuerpos monoclonales agon�?sticos epha2 y métodos de uso de los mismos. |
| US20050152899A1 (en) * | 2002-05-10 | 2005-07-14 | Kinch Michael S. | EphA2 agonistic monoclonal antibodies and methods of use thereof |
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| WO2003099313A1 (en) * | 2002-05-23 | 2003-12-04 | Purdue Research Foundation | Low molecular weight protein tyrosine phosphatase (lmw-ptp) as a diagnostic and therapeutic target |
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| US20050153923A1 (en) * | 2003-12-04 | 2005-07-14 | Kinch Michael S. | Targeted drug delivery using EphA2 or EphA4 binding moieties |
| WO2005056766A2 (en) * | 2003-12-04 | 2005-06-23 | Medimmune, Inc. | TARGETED DRUG DELIVERY USING EphA2 OR Eph4 BINDING MOIETIES |
| WO2005067460A2 (en) * | 2003-12-24 | 2005-07-28 | Medimmune, Inc. | Epha2 vaccines |
| DE102004010050A1 (de) * | 2004-03-02 | 2005-09-22 | Bayer Healthcare Ag | Spezifische monoklonale und polyklonale Antikörper für Repinotan und dessen ringoffene Form |
| CN102718867A (zh) | 2004-03-12 | 2012-10-10 | 瓦斯基因治疗公司 | 结合ephb4、抑制血管发生和肿瘤生长的抗体 |
| US7977463B2 (en) | 2004-03-12 | 2011-07-12 | Vasgene Therapeutics, Inc. | Polypeptide compounds for inhibiting angiogenesis and tumor growth |
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| EP2574341B1 (en) | 2004-03-29 | 2017-03-29 | University Of South Florida | Effective treatment of tumors and cancer with triciribine phosphate |
| US20100009929A1 (en) | 2004-03-29 | 2010-01-14 | Cheng Jin Q | Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof |
| US20100173864A1 (en) | 2004-03-29 | 2010-07-08 | Cheng Jin Q | Compositions including triciribine and one or more platinum compounds and methods of use thereof |
| US20100009928A1 (en) | 2004-03-29 | 2010-01-14 | Cheng Jin Q | Compositions including triciribine and taxanes and methods of use thereof |
| US20100028339A1 (en) | 2004-03-29 | 2010-02-04 | Cheng Jin Q | Compositions including triciribine and trastuzumab and methods of use thereof |
| US7691379B2 (en) | 2004-04-12 | 2010-04-06 | Medimmune, Llc | Anti-IL-9 antibody formulations |
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| WO2006023420A2 (en) * | 2004-08-16 | 2006-03-02 | Medimmune, Inc. | Integrin antagonists with enhanced antibody dependent cell-mediated cytotoxicity activity |
| US20060204512A1 (en) | 2004-09-23 | 2006-09-14 | Vasgene Therapeutics, Inc. | Polypeptide compounds for inhibiting angiogenesis and tumor growth |
| CA2584130A1 (en) * | 2004-10-18 | 2006-04-27 | Medimmune, Inc. | High cell density process for growth of listeria |
| JP2008518207A (ja) * | 2004-10-21 | 2008-05-29 | ザ ペン ステート リサーチ ファウンデーション | Eph受容体腫瘍バイオマーカー |
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| EP2422811A2 (en) | 2004-10-27 | 2012-02-29 | MedImmune, LLC | Modulation of antibody specificity by tailoring the affinity to cognate antigens |
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| AU2006331775A1 (en) * | 2005-12-21 | 2007-07-05 | Medimmune, Llc | Affinity optimized EphA2 agonistic antibodies and methods of use thereof |
| NZ574215A (en) | 2006-07-18 | 2012-07-27 | Sanofi Aventis | Antagonist antibody against epha2 for the treatment of cancer |
| CN101918844A (zh) * | 2007-06-18 | 2010-12-15 | 米迪缪尼有限公司 | 表达epha2和erbb2的细胞的协同治疗 |
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| US8975377B2 (en) | 2007-08-13 | 2015-03-10 | Vasgene Therapeutics, Inc | Cancer treatment using humanized antibodies that bind to EphB4 |
| WO2009028639A1 (ja) * | 2007-08-30 | 2009-03-05 | Daiichi Sankyo Company, Limited | 抗epha2抗体 |
| US8669349B2 (en) | 2008-04-02 | 2014-03-11 | Macrogenics, Inc. | BCR-complex-specific antibodies and methods of using same |
| AU2010242914B2 (en) | 2009-04-29 | 2014-11-13 | Trellis Bioscience, Llc | Improved antibodies immunoreactive with heregulin-coupled HER3 |
| US8840889B2 (en) | 2009-08-13 | 2014-09-23 | The Johns Hopkins University | Methods of modulating immune function |
| UY32914A (es) | 2009-10-02 | 2011-04-29 | Sanofi Aventis | Anticuerpos que se usan específicamente al receptor epha2 |
| CN102666874B (zh) | 2009-10-07 | 2016-06-01 | 宏观基因有限公司 | 由于岩藻糖基化程度的改变而表现出改善的效应子功能的含Fc区的多肽及其使用方法 |
| KR20130056855A (ko) | 2010-03-01 | 2013-05-30 | 카리스 라이프 사이언스 룩셈부르크 홀딩스 | 치료진단용 생물학적 지표들 |
| PH12012501751A1 (en) | 2010-03-04 | 2012-11-12 | Macrogenics Inc | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
| DK2542256T3 (da) | 2010-03-04 | 2019-08-26 | Macrogenics Inc | Antistoffer reagerende med b7-h3, immunologisk aktive fragmenter deraf og anvendelser deraf |
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| KR20130048242A (ko) * | 2010-07-22 | 2013-05-09 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 항-종양 항원 항체 및 이용 방법 |
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| AU2012216627A1 (en) * | 2011-11-14 | 2013-05-30 | Newcastle Innovation Ltd. | Composition and methods for the diagnosis, prognosis and treatment of leukemia |
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| TWI742423B (zh) | 2014-05-29 | 2021-10-11 | 美商宏觀基因股份有限公司 | 特異性結合多種癌症抗原的三特異性結合分子和其使用方法 |
| TWI781098B (zh) | 2016-04-15 | 2022-10-21 | 美商宏觀基因股份有限公司 | 新穎的b7-h3-結合分子、其抗體藥物綴合物及其使用方法 |
| JPWO2018135653A1 (ja) | 2017-01-23 | 2020-01-09 | 学校法人 東洋大学 | 抗epha2抗体及びこれを用いたepha2の免疫学的検出 |
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| US20050152899A1 (en) * | 2002-05-10 | 2005-07-14 | Kinch Michael S. | EphA2 agonistic monoclonal antibodies and methods of use thereof |
| AU2003256823B9 (en) * | 2002-07-25 | 2009-01-08 | Medimmune, Llc | Methods of treating and preventing RSV, hMPV, and PIV using anti-RSV, anti-hMPV, and anti-PIV antibodies |
| WO2004020583A2 (en) * | 2002-08-27 | 2004-03-11 | Bristol-Myers Squibb Company | Polynucleotide predictor set for identifying protein tyrosine kinase modulators |
| EP1553963A4 (en) * | 2002-09-24 | 2006-05-03 | Burnham Inst | NEW MEANS FOR MODULATING EPH RECEPTOR ACTIVITY |
| WO2004091519A2 (en) * | 2003-04-11 | 2004-10-28 | Medimmune, Inc. | Methods of preventing or treating respiratory conditions |
| EP1613273B1 (en) * | 2003-04-11 | 2012-06-13 | MedImmune, LLC | Recombinant il-9 antibodies and uses thereof |
| JP2006524693A (ja) * | 2003-04-11 | 2006-11-02 | メディミューン,インコーポレーテッド | EphA2および非腫瘍性過増殖性細胞障害 |
-
2003
- 2003-05-12 US US10/436,782 patent/US20040028685A1/en not_active Abandoned
- 2003-05-12 ES ES03750125T patent/ES2373715T3/es not_active Expired - Lifetime
- 2003-05-12 AU AU2003243228A patent/AU2003243228B2/en not_active Ceased
- 2003-05-12 JP JP2004502947A patent/JP4557714B2/ja not_active Expired - Fee Related
- 2003-05-12 WO PCT/US2003/015044 patent/WO2003094859A2/en not_active Ceased
- 2003-05-12 AT AT03750125T patent/ATE525398T1/de not_active IP Right Cessation
- 2003-05-12 EP EP03750125A patent/EP1519956B1/en not_active Expired - Lifetime
- 2003-05-12 CA CA002485373A patent/CA2485373A1/en not_active Abandoned
-
2007
- 2007-03-12 US US11/717,799 patent/US20070166314A1/en not_active Abandoned
-
2009
- 2009-06-25 AU AU2009202542A patent/AU2009202542A1/en not_active Abandoned
-
2010
- 2010-04-07 US US12/755,468 patent/US20100278838A1/en not_active Abandoned
- 2010-05-19 JP JP2010115398A patent/JP2010246546A/ja active Pending
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