JP2005534752A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2005534752A5 JP2005534752A5 JP2004525093A JP2004525093A JP2005534752A5 JP 2005534752 A5 JP2005534752 A5 JP 2005534752A5 JP 2004525093 A JP2004525093 A JP 2004525093A JP 2004525093 A JP2004525093 A JP 2004525093A JP 2005534752 A5 JP2005534752 A5 JP 2005534752A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- antigen
- galnac
- binding fragment
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012634 fragment Substances 0.000 claims 15
- 150000001875 compounds Chemical class 0.000 claims 12
- 239000000427 antigen Substances 0.000 claims 11
- 108091007433 antigens Proteins 0.000 claims 11
- 102000036639 antigens Human genes 0.000 claims 11
- 230000027455 binding Effects 0.000 claims 11
- 238000000034 method Methods 0.000 claims 9
- 241000589876 Campylobacter Species 0.000 claims 7
- 244000144972 livestock Species 0.000 claims 7
- 241000196324 Embryophyta Species 0.000 claims 6
- 244000052769 pathogen Species 0.000 claims 6
- 239000008194 pharmaceutical composition Substances 0.000 claims 6
- 241001465754 Metazoa Species 0.000 claims 5
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 4
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 239000000523 sample Substances 0.000 claims 4
- 241000282836 Camelus dromedarius Species 0.000 claims 3
- 238000009007 Diagnostic Kit Methods 0.000 claims 3
- 235000017274 Diospyros sandwicensis Nutrition 0.000 claims 3
- 241000282412 Homo Species 0.000 claims 3
- 241000282838 Lama Species 0.000 claims 3
- 241000282826 Camelus Species 0.000 claims 2
- 102000003886 Glycoproteins Human genes 0.000 claims 2
- 108090000288 Glycoproteins Proteins 0.000 claims 2
- 229940024606 amino acid Drugs 0.000 claims 2
- 235000001014 amino acid Nutrition 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 235000013361 beverage Nutrition 0.000 claims 2
- 150000004676 glycans Chemical class 0.000 claims 2
- 230000001717 pathogenic effect Effects 0.000 claims 2
- PZUPAGRIHCRVKN-UHFFFAOYSA-N 5-[5-[3,4-dihydroxy-6-[(3,4,5-trihydroxyoxan-2-yl)oxymethyl]-5-[3,4,5-trihydroxy-6-[(3,4,5-trihydroxyoxan-2-yl)oxymethyl]oxan-2-yl]oxyoxan-2-yl]oxy-3,4-dihydroxy-6-[(3,4,5-trihydroxyoxan-2-yl)oxymethyl]oxan-2-yl]oxy-6-(hydroxymethyl)oxane-2,3,4-triol Chemical compound OCC1OC(O)C(O)C(O)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(COC4C(C(O)C(O)CO4)O)O3)O)C(COC3C(C(O)C(O)CO3)O)O2)O)C(COC2C(C(O)C(O)CO2)O)O1 PZUPAGRIHCRVKN-UHFFFAOYSA-N 0.000 claims 1
- DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 claims 1
- 241000894006 Bacteria Species 0.000 claims 1
- 206010051226 Campylobacter infection Diseases 0.000 claims 1
- 241000588724 Escherichia coli Species 0.000 claims 1
- DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 claims 1
- 238000005481 NMR spectroscopy Methods 0.000 claims 1
- 102000015636 Oligopeptides Human genes 0.000 claims 1
- 108010038807 Oligopeptides Proteins 0.000 claims 1
- 239000000654 additive Substances 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- 229960001230 asparagine Drugs 0.000 claims 1
- 235000009582 asparagine Nutrition 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 238000011109 contamination Methods 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003337 fertilizer Substances 0.000 claims 1
- 210000003754 fetus Anatomy 0.000 claims 1
- 239000003673 groundwater Substances 0.000 claims 1
- 238000004008 high resolution magic-angle spinning Methods 0.000 claims 1
- 230000002163 immunogen Effects 0.000 claims 1
- 229960001438 immunostimulant agent Drugs 0.000 claims 1
- 239000003022 immunostimulating agent Substances 0.000 claims 1
- 230000003308 immunostimulating effect Effects 0.000 claims 1
- 238000004091 panning Methods 0.000 claims 1
- 244000144977 poultry Species 0.000 claims 1
- 239000002689 soil Substances 0.000 claims 1
- 230000009870 specific binding Effects 0.000 claims 1
- 238000004611 spectroscopical analysis Methods 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Images
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39973502P | 2002-08-01 | 2002-08-01 | |
| US60/399,735 | 2002-08-01 | ||
| PCT/CA2003/001156 WO2004013151A2 (en) | 2002-08-01 | 2003-07-30 | Campylobacter glycans and glycopeptides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005534752A JP2005534752A (ja) | 2005-11-17 |
| JP2005534752A5 true JP2005534752A5 (enExample) | 2006-09-07 |
| JP4718174B2 JP4718174B2 (ja) | 2011-07-06 |
Family
ID=31495764
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004525093A Expired - Fee Related JP4718174B2 (ja) | 2002-08-01 | 2003-07-30 | カンピロバクターグリカンおよびグリコペプチド |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7598354B2 (enExample) |
| EP (1) | EP1527080B1 (enExample) |
| JP (1) | JP4718174B2 (enExample) |
| CN (1) | CN1671722A (enExample) |
| AU (1) | AU2003254665C1 (enExample) |
| BR (1) | BR0312896A (enExample) |
| CA (1) | CA2494223C (enExample) |
| ES (1) | ES2391525T3 (enExample) |
| WO (1) | WO2004013151A2 (enExample) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7214660B2 (en) * | 2001-10-10 | 2007-05-08 | Neose Technologies, Inc. | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
| US7173003B2 (en) | 2001-10-10 | 2007-02-06 | Neose Technologies, Inc. | Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF |
| CA2477794C (en) | 2002-03-07 | 2013-08-20 | Eidgenoessische Technische Hochschule Zuerich | System and method for the production of recombinant glycosylated proteins in a prokaryotic host |
| AU2002952121A0 (en) * | 2002-10-17 | 2002-10-31 | Alchemia Limited | Novel carbohydrate based anti-bacterials |
| SG155777A1 (en) | 2003-04-09 | 2009-10-29 | Neose Technologies Inc | Glycopegylation methods and proteins/peptides produced by the methods |
| WO2005012484A2 (en) | 2003-07-25 | 2005-02-10 | Neose Technologies, Inc. | Antibody-toxin conjugates |
| US8633157B2 (en) | 2003-11-24 | 2014-01-21 | Novo Nordisk A/S | Glycopegylated erythropoietin |
| US20080305992A1 (en) | 2003-11-24 | 2008-12-11 | Neose Technologies, Inc. | Glycopegylated erythropoietin |
| US20080015142A1 (en) * | 2003-12-03 | 2008-01-17 | Defrees Shawn | Glycopegylated Follicle Stimulating Hormone |
| US20080300173A1 (en) | 2004-07-13 | 2008-12-04 | Defrees Shawn | Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1] |
| HUE026826T2 (en) | 2004-10-29 | 2016-07-28 | Ratiopharm Gmbh | Modeling and glycopegylation of fibroblast growth factor (FGF) |
| US9029331B2 (en) | 2005-01-10 | 2015-05-12 | Novo Nordisk A/S | Glycopegylated granulocyte colony stimulating factor |
| EP1871795A4 (en) | 2005-04-08 | 2010-03-31 | Biogenerix Ag | COMPOSITIONS AND METHOD FOR PRODUCING GLYCOSYLATION MUTANTS OF A PROTEASE-RESISTANT HUMAN GROWTH HORMONE |
| JP5356807B2 (ja) | 2005-05-11 | 2013-12-04 | アイトヘネーシシェ テフニーシェ ホフシューレ チューリッヒ | 原核細胞由来の組み換えn−グリコシル化タンパク質 |
| US20070105755A1 (en) * | 2005-10-26 | 2007-05-10 | Neose Technologies, Inc. | One pot desialylation and glycopegylation of therapeutic peptides |
| US20090048440A1 (en) | 2005-11-03 | 2009-02-19 | Neose Technologies, Inc. | Nucleotide Sugar Purification Using Membranes |
| US20080248959A1 (en) | 2006-07-21 | 2008-10-09 | Neose Technologies, Inc. | Glycosylation of peptides via o-linked glycosylation sequences |
| JP2010505874A (ja) | 2006-10-03 | 2010-02-25 | ノヴォ ノルディスク アー/エス | ポリペプチドコンジュゲートの精製方法 |
| RS52845B (sr) | 2007-04-03 | 2013-12-31 | Biogenerix Ag | Postupci tretmana korišćenjem glikopegiliranog g-csf |
| JP5876649B2 (ja) | 2007-06-12 | 2016-03-02 | ラツィオファルム ゲーエムベーハーratiopharm GmbH | ヌクレオチド糖の改良製造法 |
| US8999668B2 (en) | 2008-01-03 | 2015-04-07 | Cornell Research Foundation, Inc. | Glycosylated protein expression in prokaryotes |
| EP2242505A4 (en) * | 2008-01-08 | 2012-03-07 | Biogenerix Ag | GLYCOCONJUGATION OF POLYPEPTIDES USING OLIGOSACCHARYLTRANSFERASES |
| HRP20181259T1 (hr) | 2008-02-20 | 2018-10-05 | Glaxosmithkline Biologicals S.A. | Biokonjugati načinjeni iz rekombinantnih n-glikoziliranih proteina iz prokariotskih stanica |
| ES2476690T3 (es) | 2008-02-27 | 2014-07-15 | Novo Nordisk A/S | Moléculas conjugadas del Factor VIII |
| PL2411503T3 (pl) * | 2009-03-27 | 2018-01-31 | Eidgenoessische Technische Hochschule Zuerich | Salmonella enterica prezentująca n-glikan z c. jejuni lub jego pochodne |
| AU2010322454B2 (en) | 2009-11-19 | 2016-05-19 | Glaxosmithkline Biologicals S.A. | Biosynthetic system that produces immunogenic polysaccharides in prokaryotic cells |
| JP5925699B2 (ja) * | 2010-02-11 | 2016-05-25 | ザ・ガバナーズ・オブ・ザ・ユニバーシティー・オブ・アルバータ | N結合型グリカン化合物 |
| US8841099B2 (en) * | 2010-04-20 | 2014-09-23 | National Research Council Of Canada | Cell-based production of nonulosonates |
| ES2844596T3 (es) | 2010-05-06 | 2021-07-22 | Glaxosmithkline Biologicals Sa | Vacunas de bioconjugados de bacterias grampositivas capsulares |
| US9308246B2 (en) | 2010-05-28 | 2016-04-12 | The United States Of America As Represented By The Secretary Of The Navy | Capsule composition for use as immunogen against Campylobacter jejuni |
| JP6135046B2 (ja) * | 2012-04-20 | 2017-05-31 | 株式会社島津製作所 | 糖ペプチドの質量分析法 |
| EP2991675B1 (en) | 2013-04-05 | 2019-07-24 | The Governors of the University of Alberta | Campylobacter vaccine |
| EP4205553A1 (en) * | 2015-01-26 | 2023-07-05 | DSM Nutritional Products, LLC | Oligosaccharide compositions for use animal feed and methods of producing thereof |
| WO2017117539A1 (en) | 2015-12-30 | 2017-07-06 | Northwestern University | Cell-free glycoprotein synthesis (cfgps) in prokaryotic cell lysates enriched with components for glycosylation |
| US10829795B2 (en) | 2016-07-14 | 2020-11-10 | Northwestern University | Method for rapid in vitro synthesis of glycoproteins via recombinant production of N-glycosylated proteins in prokaryotic cell lysates |
| US11898187B2 (en) | 2017-08-15 | 2024-02-13 | Northwestern University | Protein glycosylation sites by rapid expression and characterization of N-glycosyltransferases |
| WO2019119134A1 (en) * | 2017-12-19 | 2019-06-27 | The Governors Of The University Of Alberta | Clostridium perfringens surface glycans and uses thereof |
| US11530432B2 (en) | 2018-03-19 | 2022-12-20 | Northwestern University | Compositions and methods for rapid in vitro synthesis of bioconjugate vaccines in vitro via production and N-glycosylation of protein carriers in detoxified prokaryotic cell lysates |
| US11725224B2 (en) | 2018-04-16 | 2023-08-15 | Northwestern University | Methods for co-activating in vitro non-standard amino acid (nsAA) incorporation and glycosylation in crude cell lysates |
| WO2020072127A2 (en) | 2018-08-03 | 2020-04-09 | Northwestern University | On demand, portable, cell-free molecular sensing platform |
| US12404533B2 (en) | 2019-01-11 | 2025-09-02 | Northwestern University | Bioconjugate vaccines' synthesis in prokaryotic cell lysates |
| US12325884B2 (en) | 2019-03-04 | 2025-06-10 | Northwestern University | Riboswitch-based fluoride sensing in cell-free extract |
| US12226410B2 (en) | 2019-10-18 | 2025-02-18 | Northwestern University | Methods for enhancing cellular clearance of pathological molecules via activation of the cellular protein ykt6 |
| US20240287564A1 (en) * | 2021-06-07 | 2024-08-29 | The University Of British Columbia | Acholetin biopolymers and methods for enzymatic synthesis |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4925796A (en) * | 1986-03-07 | 1990-05-15 | Massachusetts Institute Of Technology | Method for enhancing glycoprotein stability |
| US5200344A (en) * | 1990-11-13 | 1993-04-06 | Blaser Martin J | Diagnostic testing for campylobacter jejuni or campylobacter coli infections using novel antigens |
| WO1995005850A1 (en) * | 1993-08-27 | 1995-03-02 | Enteric Research Laboratories, Inc. | Campylobacter jejuni antigens, and methods for their production and use |
| WO1996007753A1 (en) * | 1994-09-06 | 1996-03-14 | Bioflexin Ab | Amino acid conjugate |
| US5840547A (en) * | 1995-01-05 | 1998-11-24 | Ramot University Authority For Applied Research & Indfustrial Development Ltd. | Bioemulsifiers |
| US6676946B2 (en) * | 1997-03-27 | 2004-01-13 | Institut Pasteur | Multiple antigen glycopeptide carbohydrate vaccine comprising the same and use thereof |
| US6699705B2 (en) * | 1999-02-01 | 2004-03-02 | National Research Council Of Canada | Campylobacter glycosyltransferases for biosynthesis of gangliosides and ganglioside mimics |
| AU3513500A (en) * | 1999-03-05 | 2000-09-21 | Trustees Of Tufts College | Emulsan and emulsan analogs immunization formulations and use |
| US6512014B2 (en) * | 2000-12-13 | 2003-01-28 | Ramot University Authority For Applied Research And Industrial Development Limited | Compositions containing bioemulsifiers and a method for their preparation |
| ES2561985T3 (es) * | 2001-10-10 | 2016-03-01 | Ratiopharm Gmbh | Remodelación y glicoconjugación de anticuerpos |
| US20030232401A1 (en) * | 2002-06-12 | 2003-12-18 | Pugia Michael J. | Bacterial test method by glycated label binding |
| US9084809B2 (en) * | 2005-09-21 | 2015-07-21 | The United States Of America As Represented By The Secretary Of The Navy | Immunogenic capsule composition for use as a vaccine component against Campylobacter jejuni |
-
2003
- 2003-07-30 CN CNA038181851A patent/CN1671722A/zh active Pending
- 2003-07-30 EP EP03766087A patent/EP1527080B1/en not_active Expired - Lifetime
- 2003-07-30 US US10/523,459 patent/US7598354B2/en not_active Expired - Lifetime
- 2003-07-30 WO PCT/CA2003/001156 patent/WO2004013151A2/en not_active Ceased
- 2003-07-30 AU AU2003254665A patent/AU2003254665C1/en not_active Expired
- 2003-07-30 CA CA2494223A patent/CA2494223C/en not_active Expired - Lifetime
- 2003-07-30 JP JP2004525093A patent/JP4718174B2/ja not_active Expired - Fee Related
- 2003-07-30 ES ES03766087T patent/ES2391525T3/es not_active Expired - Lifetime
- 2003-07-30 BR BR0312896-2A patent/BR0312896A/pt not_active IP Right Cessation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2005534752A5 (enExample) | ||
| CA2494223A1 (en) | Campylobacter glycans and glycopeptides | |
| Lee et al. | Causative agents and epidemiology of diarrhea in Korean native calves | |
| Werner et al. | Antibiotic resistant enterococci—Tales of a drug resistance gene trafficker | |
| Leitner et al. | Development of a Staphylococcus aureus vaccine against mastitis in dairy cows. II. Field trial | |
| Zhao et al. | Immersion vaccination of Mandarin fish Siniperca chuatsi against infectious spleen and kidney necrosis virus with a SWCNTs-based subunit vaccine | |
| US20090324648A1 (en) | Vaccine for edwardsiella disease and streptococcal disease in fish | |
| PH12015501888B1 (en) | Novel bacteriophage and antibacterial composition comprising the same | |
| ES2527470T3 (es) | Composición farmacéutica que comprende un inhibidor de la bomba de protones y un prebiótico para el tratamiento de lesiones ulcerosas del estómago y el duodeno | |
| CA2257826A1 (en) | Helicobacter pylori adhesin binding group antigen | |
| CN102139103B (zh) | 半滑舌鳎美人鱼发光杆菌疫苗的制备与使用方法 | |
| TWI433651B (zh) | 新穎乳酸菌株、含彼之組合物及其用途 | |
| JP2006525981A (ja) | アリシン | |
| CN101002947B (zh) | 一种用于细菌病治疗的靶向药物及其制备方法 | |
| Sombe et al. | Optimization and Field Trial of an Aeromonas hydrophila Vaccine candidate for motile aeromonads septicemia in farmed Nile tilapia in Tanzania | |
| KR19980081625A (ko) | 장관 출혈성 대장균에 의한 감염증의 예방제 및 치료제 | |
| CN104388394B (zh) | 水貂细小病毒弱毒疫苗株及其在制备水貂细小病毒弱毒疫苗中的用途 | |
| Singh et al. | Therapeutic management of Bovine Brucellosis in endemically infected dairy cattle herd of native Sahiwal breed. | |
| Tarello et al. | Corynebacterium pseudotuberculosis and Corynebacterium renale isolated from two Arabian oryx (Oryx leucoryx) | |
| RU2179846C2 (ru) | Средство для профилактики и лечения желудочно-кишечных и респираторных заболеваний телят | |
| KR102003795B1 (ko) | 신규한 시가톡신 생성 대장균 특이 박테리오파지 ecoh1 및 이를 포함하는 항균 조성물 | |
| RU2429871C1 (ru) | Препарат для лечения желудочно-кишечных болезней телят и способ его применения | |
| TW200423956A (en) | Adjuvanted bovine vaccines | |
| US10596206B1 (en) | Probiotic compositions and methods of use | |
| CN109913391B (zh) | 罗非鱼源海豚链球菌弱毒株及应用 |