JP2005532254A5 - - Google Patents

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Publication number
JP2005532254A5
JP2005532254A5 JP2003541765A JP2003541765A JP2005532254A5 JP 2005532254 A5 JP2005532254 A5 JP 2005532254A5 JP 2003541765 A JP2003541765 A JP 2003541765A JP 2003541765 A JP2003541765 A JP 2003541765A JP 2005532254 A5 JP2005532254 A5 JP 2005532254A5
Authority
JP
Japan
Prior art keywords
uridine
tetraphosphate
triphosphate
alkyl
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2003541765A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005532254A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2002/035775 external-priority patent/WO2003039473A2/en
Publication of JP2005532254A publication Critical patent/JP2005532254A/ja
Publication of JP2005532254A5 publication Critical patent/JP2005532254A5/ja
Pending legal-status Critical Current

Links

JP2003541765A 2001-11-06 2002-11-06 炎症性疾患を治療又は予防する方法 Pending JP2005532254A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33782801P 2001-11-06 2001-11-06
PCT/US2002/035775 WO2003039473A2 (en) 2001-11-06 2002-11-06 Method for treating or preventing inflammatory diseases

Publications (2)

Publication Number Publication Date
JP2005532254A JP2005532254A (ja) 2005-10-27
JP2005532254A5 true JP2005532254A5 (https=) 2006-01-05

Family

ID=23322192

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003541765A Pending JP2005532254A (ja) 2001-11-06 2002-11-06 炎症性疾患を治療又は予防する方法

Country Status (11)

Country Link
US (1) US7256183B2 (https=)
EP (1) EP1450820A4 (https=)
JP (1) JP2005532254A (https=)
KR (1) KR20050043761A (https=)
CN (1) CN1612739A (https=)
AR (1) AR037263A1 (https=)
BR (1) BR0213897A (https=)
CA (1) CA2465894A1 (https=)
MX (1) MXPA04004215A (https=)
TW (1) TW200300692A (https=)
WO (1) WO2003039473A2 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003028712A2 (en) * 2001-09-28 2003-04-10 Universite Libre De Bruxelles Purinergic and pyrimidinergic receptor agonists for the treatment of activated cd4+ t lymphocyte-mediated immune diseases
JPWO2004075906A1 (ja) * 2003-02-26 2006-06-01 リジェンティス株式会社 抗炎症剤及び抗炎症性医療材料
GB0417886D0 (en) * 2004-08-11 2004-09-15 Univ Cardiff Method and means for enhanced pulmonary delivery
SE529064C2 (sv) * 2005-01-03 2007-04-24 Selectica Pharmaceuticals Ab Topiska kompositioner
GB0502250D0 (en) * 2005-02-03 2005-03-09 Ic Vec Ltd Use
WO2007041495A2 (en) * 2005-09-29 2007-04-12 University Of California, San Diego Dampening humoral and innate immunity by inhibition of ppgalnact-1
WO2008113072A2 (en) * 2007-03-15 2008-09-18 Board Of Regents, The University Of Texas System Gpcr enhanced neuroprotection to treat brain injury
US8168597B2 (en) * 2008-10-22 2012-05-01 Inspire Pharmaceuticals, Inc. Method for treating cystic fibrosis
GB201209244D0 (en) * 2012-05-25 2012-07-04 Globalacorn Ltd Compositions
US10111904B2 (en) * 2013-01-09 2018-10-30 Berlock Aps Micron-sized gold, kit comprising said gold and its use as a non-toxic immune suppressor
US20150031712A1 (en) 2013-03-12 2015-01-29 Moshe Rogosnitzky Therapeutic Compositions Containing Dipyridamole and Treatment Packs Including Such Compositions and Methods for Producing Same
GB201320962D0 (en) * 2013-11-27 2014-01-08 Globalacorn Ltd Compositions
GB201320959D0 (en) * 2013-11-27 2014-01-08 Globalacorn Ltd Compositions

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5292498A (en) 1991-06-19 1994-03-08 The University Of North Carolina At Chapel Hill Method of treating lung disease with uridine triphosphates
US6255059B1 (en) 1993-03-31 2001-07-03 Cadus Pharmaceutical Corporation Methods for identifying G protein coupled receptor effectors
US5656256A (en) 1994-12-14 1997-08-12 The University Of North Carolina At Chapel Hill Methods of treating lung disease by an aerosol containing benzamil or phenamil
US6147056A (en) * 1995-06-06 2000-11-14 Trustees Of Boston University Use of locally applied DNA fragments
US5635160A (en) 1995-06-07 1997-06-03 The University Of North Carolina At Chapel Hill Dinucleotides useful for the treatment of cystic fibrosis and for hydrating mucus secretions
US5628984A (en) 1995-07-31 1997-05-13 University Of North Carolina At Chapel Hill Method of detecting lung disease
US6423694B1 (en) 1996-02-21 2002-07-23 Inspire Pharmaceuticals, Inc. Method of treating otitis media with uridine triphosphates and related compounds
US5837861A (en) 1997-02-10 1998-11-17 Inspire Pharmaceuticals, Inc. Dinucleotides and their use as modulators of mucociliary clearance and ciliary beat frequency
US5900407A (en) 1997-02-06 1999-05-04 Inspire Pharmaceuticals, Inc. Method of treating dry eye disease with uridine triphosphates and related compounds
NZ332426A (en) 1996-03-27 2000-09-29 Univ North Carolina Method of treating diseases involving dysfunction of ciliary movement such as ciliary dyskinesia and infertility with uridine triphosphates (UTP) and related compounds
US5789391A (en) * 1996-07-03 1998-08-04 Inspire Pharmaceuticals, Inc. Method of treating sinusitis with uridine triphosphates and related compounds
US5968913A (en) 1996-07-03 1999-10-19 Inspire Pharmaceuticals, Inc. Pharmaceutical compositions of uridine triphosphate
US5763447C1 (en) 1996-07-23 2002-05-07 Inspire Pharmaceuticals Method of preventing or treating pneumonia in immobilized patients with uridine triphosphates and related compounds
WO1998015835A1 (en) 1996-10-08 1998-04-16 Inspire Pharmaceuticals, Inc. Method of early lung cancer detection via sputum induction and analysis of sputum to detect cancer associated substances
EP0929218A4 (en) * 1996-10-30 2001-05-16 Univ North Carolina P2Y RECEPTOR ANTAGONISTS
US6159952A (en) 1996-11-07 2000-12-12 Inspire Pharmaceuticals, Inc. Method of treating bronchitis with uridine triphosphate and related compounds
DK0981534T3 (da) * 1997-02-06 2006-09-04 Inspire Pharmaceuticals Inc Dinukleotider og deres anvendelser
EP1011686B9 (en) * 1997-03-25 2011-02-09 Duska Scientific Co Modulation of human mast cell activation
US6462028B2 (en) 1997-07-25 2002-10-08 Inspire Pharmaceuticals, Inc. Method of promoting cervical and vaginal secretions
ID29198A (id) * 1997-08-29 2001-08-09 Univ North Carolina Pemakaian uridin 5'-difosfat dan persamaannya untuk mengobati penyakit paru-paru
CA2332540A1 (en) * 1998-05-22 1999-12-02 Benjamin R. Yerxa Therapeutic dinucleotide and derivatives
EP1143896B1 (en) * 1998-10-20 2006-12-13 The University of North Carolina at Chapel Hill Methods of hydrating the nasal mucosal surface
WO2000050024A2 (en) * 1999-02-26 2000-08-31 Inspire Pharmaceuticals, Inc. Method of promoting mucosal hydration with certain uridine, adenine and cytidine diphosphates and analogs thereof
AU2603101A (en) * 1999-12-22 2001-07-03 Inspire Pharmaceuticals, Inc. Method of treating gastrointestinal tract disease with purinergic receptor agonists
US6610274B1 (en) * 2000-12-22 2003-08-26 Wallace J. Gardner Anti-inflammatory composition comprising tetracycline
WO2003022255A2 (en) * 2001-09-05 2003-03-20 Vsl Pharmaceuticals, Inc. Lactic acid bacteria comprising unmethylated cytosine-guanine dinucleotides for use in therapy

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