JP2005531335A5 - - Google Patents
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- Publication number
- JP2005531335A5 JP2005531335A5 JP2003546961A JP2003546961A JP2005531335A5 JP 2005531335 A5 JP2005531335 A5 JP 2005531335A5 JP 2003546961 A JP2003546961 A JP 2003546961A JP 2003546961 A JP2003546961 A JP 2003546961A JP 2005531335 A5 JP2005531335 A5 JP 2005531335A5
- Authority
- JP
- Japan
- Prior art keywords
- medical device
- extrusion molding
- long
- elongate
- molding material
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000000463 material Substances 0.000 claims description 78
- 238000001125 extrusion Methods 0.000 claims description 62
- 229920001477 hydrophilic polymer Polymers 0.000 claims description 54
- 230000005291 magnetic effect Effects 0.000 claims description 48
- 230000005298 paramagnetic effect Effects 0.000 claims description 47
- 238000002595 magnetic resonance imaging Methods 0.000 claims description 39
- 229920000642 polymer Polymers 0.000 claims description 34
- 238000000034 method Methods 0.000 claims description 27
- 239000000126 substance Substances 0.000 claims description 19
- 150000002500 ions Chemical class 0.000 claims description 18
- 238000000576 coating method Methods 0.000 claims description 14
- 229910052751 metal Inorganic materials 0.000 claims description 12
- 239000002184 metal Substances 0.000 claims description 12
- 239000011248 coating agent Substances 0.000 claims description 11
- 229910052688 Gadolinium Inorganic materials 0.000 claims description 10
- UIWYJDYFSGRHKR-UHFFFAOYSA-N gadolinium atom Chemical compound [Gd] UIWYJDYFSGRHKR-UHFFFAOYSA-N 0.000 claims description 10
- 230000008569 process Effects 0.000 claims description 10
- 229920002635 polyurethane Polymers 0.000 claims description 8
- 239000004814 polyurethane Substances 0.000 claims description 8
- 239000004952 Polyamide Substances 0.000 claims description 6
- 230000010354 integration Effects 0.000 claims description 6
- 239000002245 particle Substances 0.000 claims description 6
- 229920002647 polyamide Polymers 0.000 claims description 6
- 229920001451 polypropylene glycol Polymers 0.000 claims description 5
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 5
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims description 5
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 5
- 150000003839 salts Chemical class 0.000 claims description 5
- 108010010803 Gelatin Proteins 0.000 claims description 4
- 229910019142 PO4 Inorganic materials 0.000 claims description 4
- 229920002614 Polyether block amide Polymers 0.000 claims description 4
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 4
- 229920002125 Sokalan® Polymers 0.000 claims description 4
- 239000001913 cellulose Substances 0.000 claims description 4
- 229920002678 cellulose Polymers 0.000 claims description 4
- 229920000159 gelatin Polymers 0.000 claims description 4
- 239000008273 gelatin Substances 0.000 claims description 4
- 235000019322 gelatine Nutrition 0.000 claims description 4
- 235000011852 gelatine desserts Nutrition 0.000 claims description 4
- FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical compound O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 claims description 4
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims description 4
- 239000010452 phosphate Substances 0.000 claims description 4
- 239000004584 polyacrylic acid Substances 0.000 claims description 4
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 4
- IZOOGPBRAOKZFK-UHFFFAOYSA-K gadopentetate Chemical compound [Gd+3].OC(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O IZOOGPBRAOKZFK-UHFFFAOYSA-K 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 3
- -1 polyethylene Polymers 0.000 claims description 3
- 230000002787 reinforcement Effects 0.000 claims description 3
- 229910052692 Dysprosium Inorganic materials 0.000 claims description 2
- 239000004677 Nylon Substances 0.000 claims description 2
- 239000004696 Poly ether ether ketone Substances 0.000 claims description 2
- 239000004698 Polyethylene Substances 0.000 claims description 2
- 239000004642 Polyimide Substances 0.000 claims description 2
- JUPQTSLXMOCDHR-UHFFFAOYSA-N benzene-1,4-diol;bis(4-fluorophenyl)methanone Chemical compound OC1=CC=C(O)C=C1.C1=CC(F)=CC=C1C(=O)C1=CC=C(F)C=C1 JUPQTSLXMOCDHR-UHFFFAOYSA-N 0.000 claims description 2
- KBQHZAAAGSGFKK-UHFFFAOYSA-N dysprosium atom Chemical compound [Dy] KBQHZAAAGSGFKK-UHFFFAOYSA-N 0.000 claims description 2
- 229920001778 nylon Polymers 0.000 claims description 2
- 229920006149 polyester-amide block copolymer Polymers 0.000 claims description 2
- 229920002530 polyetherether ketone Polymers 0.000 claims description 2
- 229920000573 polyethylene Polymers 0.000 claims description 2
- 229920001721 polyimide Polymers 0.000 claims description 2
- 239000012778 molding material Substances 0.000 claims 27
- 239000013522 chelant Substances 0.000 claims 2
- 150000004696 coordination complex Chemical class 0.000 claims 1
- WTFXARWRTYJXII-UHFFFAOYSA-N iron(2+);iron(3+);oxygen(2-) Chemical compound [O-2].[O-2].[O-2].[O-2].[Fe+2].[Fe+3].[Fe+3] WTFXARWRTYJXII-UHFFFAOYSA-N 0.000 claims 1
- 239000006249 magnetic particle Substances 0.000 claims 1
- 239000002905 metal composite material Substances 0.000 claims 1
- 229940126585 therapeutic drug Drugs 0.000 claims 1
- 239000010410 layer Substances 0.000 description 17
- 239000002872 contrast media Substances 0.000 description 9
- 239000002907 paramagnetic material Substances 0.000 description 9
- 210000001519 tissue Anatomy 0.000 description 9
- 230000000694 effects Effects 0.000 description 5
- 238000003384 imaging method Methods 0.000 description 5
- 230000004044 response Effects 0.000 description 5
- 230000015572 biosynthetic process Effects 0.000 description 4
- 210000001124 body fluid Anatomy 0.000 description 4
- 239000010839 body fluid Substances 0.000 description 4
- 230000002708 enhancing effect Effects 0.000 description 4
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 230000002349 favourable effect Effects 0.000 description 3
- 230000000704 physical effect Effects 0.000 description 3
- 239000011241 protective layer Substances 0.000 description 3
- 238000003786 synthesis reaction Methods 0.000 description 3
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 description 2
- 150000000921 Gadolinium Chemical class 0.000 description 2
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 description 2
- 239000004020 conductor Substances 0.000 description 2
- 229940039231 contrast media Drugs 0.000 description 2
- 238000004132 cross linking Methods 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000005684 electric field Effects 0.000 description 2
- 239000007943 implant Substances 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- 239000004810 polytetrafluoroethylene Substances 0.000 description 2
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 2
- 229920000915 polyvinyl chloride Polymers 0.000 description 2
- 230000005855 radiation Effects 0.000 description 2
- 230000003014 reinforcing effect Effects 0.000 description 2
- QPCDCPDFJACHGM-UHFFFAOYSA-N N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(=O)O)CCN(CC(O)=O)CC(O)=O QPCDCPDFJACHGM-UHFFFAOYSA-N 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 206010070834 Sensitisation Diseases 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 238000002679 ablation Methods 0.000 description 1
- 238000002399 angioplasty Methods 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 239000002738 chelating agent Substances 0.000 description 1
- 238000003618 dip coating Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 229920005570 flexible polymer Polymers 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 150000004677 hydrates Chemical class 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000010253 intravenous injection Methods 0.000 description 1
- 230000005865 ionizing radiation Effects 0.000 description 1
- 230000001050 lubricating effect Effects 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 238000000968 medical method and process Methods 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000005408 paramagnetism Effects 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 230000008313 sensitization Effects 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/995,528 US20030100829A1 (en) | 2001-11-27 | 2001-11-27 | Medical devices with magnetic resonance visibility enhancing material |
| US09/995,528 | 2001-11-27 | ||
| PCT/US2002/028202 WO2003045462A1 (en) | 2001-11-27 | 2002-09-05 | Medical devices with magnetic resonance visibility enhancing material |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005531335A JP2005531335A (ja) | 2005-10-20 |
| JP2005531335A5 true JP2005531335A5 (enExample) | 2009-09-10 |
| JP4790215B2 JP4790215B2 (ja) | 2011-10-12 |
Family
ID=25541924
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003546961A Expired - Fee Related JP4790215B2 (ja) | 2001-11-27 | 2002-09-05 | 磁気共鳴視感度向上材料を有する医療装置 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20030100829A1 (enExample) |
| EP (1) | EP1465682B1 (enExample) |
| JP (1) | JP4790215B2 (enExample) |
| AT (1) | ATE429939T1 (enExample) |
| AU (1) | AU2002332847A1 (enExample) |
| CA (1) | CA2468105A1 (enExample) |
| DE (1) | DE60232190D1 (enExample) |
| ES (1) | ES2326162T3 (enExample) |
| WO (1) | WO2003045462A1 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030100829A1 (en) * | 2001-11-27 | 2003-05-29 | Sheng-Ping Zhong | Medical devices with magnetic resonance visibility enhancing material |
| US7792568B2 (en) * | 2003-03-17 | 2010-09-07 | Boston Scientific Scimed, Inc. | MRI-visible medical devices |
| US20040220534A1 (en) * | 2003-04-29 | 2004-11-04 | Martens Paul W. | Medical device with antimicrobial layer |
| JP2008522747A (ja) * | 2004-12-08 | 2008-07-03 | クック・インコーポレイテッド | 造影剤でコーティングされた医療機器 |
| US7723408B2 (en) * | 2005-02-16 | 2010-05-25 | Georgia Tech Research Corporation | Composite materials having low filler percolation thresholds and methods of controlling filler interconnectivity |
| US7778684B2 (en) * | 2005-08-08 | 2010-08-17 | Boston Scientific Scimed, Inc. | MRI resonator system with stent implant |
| US7945335B2 (en) * | 2005-11-17 | 2011-05-17 | Intematix Corporation | Remotely RF powered conformable thermal applicators |
| EP1956975A2 (en) | 2005-11-29 | 2008-08-20 | Surgi-Vision, Inc. | Mri-guided localization and/or lead placement systems, related methods, devices and computer program products |
| US20070239256A1 (en) * | 2006-03-22 | 2007-10-11 | Jan Weber | Medical devices having electrical circuits with multilayer regions |
| US8315689B2 (en) | 2007-09-24 | 2012-11-20 | MRI Interventions, Inc. | MRI surgical systems for real-time visualizations using MRI image data and predefined data of surgical tools |
| DE102008024976A1 (de) * | 2008-05-23 | 2009-12-17 | Marvis Technologies Gmbh | Medizinisches Instrument |
| US8226603B2 (en) | 2008-09-25 | 2012-07-24 | Abbott Cardiovascular Systems Inc. | Expandable member having a covering formed of a fibrous matrix for intraluminal drug delivery |
| US8049061B2 (en) | 2008-09-25 | 2011-11-01 | Abbott Cardiovascular Systems, Inc. | Expandable member formed of a fibrous matrix having hydrogel polymer for intraluminal drug delivery |
| US8076529B2 (en) | 2008-09-26 | 2011-12-13 | Abbott Cardiovascular Systems, Inc. | Expandable member formed of a fibrous matrix for intraluminal drug delivery |
| CN102625669B (zh) | 2009-06-08 | 2015-09-23 | 核磁共振成像介入技术有限公司 | 能够近实时地跟踪和生成柔性体内装置的动态可视化的mri导向的介入系统 |
| WO2010148088A2 (en) | 2009-06-16 | 2010-12-23 | Surgivision, Inc. | Mri-guided devices and mri-guided interventional systems that can track and generate dynamic visualizations of the devices in near real time |
| WO2011119536A1 (en) | 2010-03-22 | 2011-09-29 | Abbott Cardiovascular Systems Inc. | Stent delivery system having a fibrous matrix covering with improved stent retention |
| EP2484388A1 (en) | 2011-02-05 | 2012-08-08 | MaRVis Technologies GmbH | Implantable or insertable MRI-detectable medical device having a coating comprising paramagnetic ions and a process for preparing it |
| EP2692365A1 (en) | 2012-08-03 | 2014-02-05 | MaRVis Medical GmbH | Implantable or insertable MRI-detectable medical device having a coating comprising paramagnetic ions and a process for preparing it |
| US10327667B2 (en) | 2016-05-13 | 2019-06-25 | Becton, Dickinson And Company | Electro-magnetic needle catheter insertion system |
| US11344220B2 (en) | 2016-05-13 | 2022-05-31 | Becton, Dickinson And Company | Invasive medical device cover with magnet |
| US11826522B2 (en) | 2016-06-01 | 2023-11-28 | Becton, Dickinson And Company | Medical devices, systems and methods utilizing permanent magnet and magnetizable feature |
| US11116419B2 (en) | 2016-06-01 | 2021-09-14 | Becton, Dickinson And Company | Invasive medical devices including magnetic region and systems and methods |
| US10583269B2 (en) * | 2016-06-01 | 2020-03-10 | Becton, Dickinson And Company | Magnetized catheters, devices, uses and methods of using magnetized catheters |
| US20170347914A1 (en) | 2016-06-01 | 2017-12-07 | Becton, Dickinson And Company | Invasive Medical Devices Including Magnetic Region And Systems And Methods |
| US11413429B2 (en) | 2016-06-01 | 2022-08-16 | Becton, Dickinson And Company | Medical devices, systems and methods utilizing permanent magnet and magnetizable feature |
| US10032552B2 (en) | 2016-08-30 | 2018-07-24 | Becton, Dickinson And Company | Cover for tissue penetrating device with integrated magnets and magnetic shielding |
| US10905497B2 (en) | 2017-04-21 | 2021-02-02 | Clearpoint Neuro, Inc. | Surgical navigation systems |
| JP2022107590A (ja) * | 2021-01-11 | 2022-07-22 | クック・メディカル・テクノロジーズ・リミテッド・ライアビリティ・カンパニー | 磁気共鳴イメージング下での治療の施行において有益な介入用医療機器及びこれに関係する方法 |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2566441A (en) * | 1946-04-29 | 1951-09-04 | Armour Res Found | Magnetic record medium and method of making the same |
| US4618518A (en) * | 1984-08-10 | 1986-10-21 | Amerace Corporation | Retroreflective sheeting and methods for making same |
| US5342607A (en) * | 1986-07-03 | 1994-08-30 | Advanced Magnetics, Inc. | Receptor mediated endocytosis type magnetic resonance imaging contrast agents |
| CA1299954C (en) * | 1987-01-13 | 1992-05-05 | Yoshio Ishitsu | Balloon catheter and method of manufacturing the same |
| US5154179A (en) * | 1987-07-02 | 1992-10-13 | Medical Magnetics, Inc. | Device construction and method facilitating magnetic resonance imaging of foreign objects in a body |
| US4989608A (en) * | 1987-07-02 | 1991-02-05 | Ratner Adam V | Device construction and method facilitating magnetic resonance imaging of foreign objects in a body |
| GB8815423D0 (en) * | 1988-06-29 | 1988-08-03 | Ici Plc | Receiver sheet |
| IE64997B1 (en) * | 1989-01-18 | 1995-10-04 | Becton Dickinson Co | Anti-infection and antithrombogenic medical articles and method for their preparation |
| JP2654195B2 (ja) * | 1989-08-22 | 1997-09-17 | 富士写真フイルム株式会社 | 磁気記録媒体 |
| US5594136A (en) * | 1989-12-21 | 1997-01-14 | Pharmacyclics, Inc. | Texaphyrin solid supports and devices |
| US5190744A (en) * | 1990-03-09 | 1993-03-02 | Salutar | Methods for detecting blood perfusion variations by magnetic resonance imaging |
| US5756688A (en) * | 1992-10-14 | 1998-05-26 | Sterling Winthrop Inc. | MR imaging compositions and methods |
| NZ265523A (en) * | 1993-04-14 | 1997-04-24 | Pharmacyclics Inc | Medical device: non-metallic member with paramagnetic ionic particles enhances viewing by magnetic imaging |
| US5817017A (en) * | 1994-04-12 | 1998-10-06 | Pharmacyclics, Inc. | Medical devices and materials having enhanced magnetic images visibility |
| IT1274038B (it) * | 1994-07-29 | 1997-07-14 | Bracco Spa | Chelanti macrociclici loro chelati e relativi usi in campo diagnostico |
| NL9401517A (nl) * | 1994-09-19 | 1996-05-01 | Cordis Europ | MR-zichtbare catheter. |
| US5728079A (en) * | 1994-09-19 | 1998-03-17 | Cordis Corporation | Catheter which is visible under MRI |
| CA2173023C (en) * | 1995-03-30 | 2001-08-28 | David Kupiecki | Liquid coils with secondary shape |
| NL1001736C2 (nl) * | 1995-11-23 | 1997-05-27 | Cordis Europ | Bij magnetische-resonantiebeeldvorming (MRI) zichtbare medische inrichting. |
| US5906606A (en) * | 1995-12-04 | 1999-05-25 | Target Therapuetics, Inc. | Braided body balloon catheter |
| US6117125A (en) * | 1996-05-02 | 2000-09-12 | Cook Incorporated | Method for predetermining uniform flow rate of a fluid from a tubular body and device therefrom |
| DE69736826T2 (de) * | 1996-12-05 | 2007-05-16 | Philips Medical Systems (Cleveland), Inc., Cleveland | Radiofrequenzspulen für Kernresonanz |
| US6165166A (en) * | 1997-04-25 | 2000-12-26 | Schneider (Usa) Inc. | Trilayer, extruded medical tubing and medical devices incorporating such tubing |
| DE19718339A1 (de) * | 1997-04-30 | 1998-11-12 | Schering Ag | Polymer beschichtete Stents, Verfahren zu ihrer Herstellung und ihre Verwendung zur Restenoseprophylaxe |
| US6272370B1 (en) * | 1998-08-07 | 2001-08-07 | The Regents Of University Of Minnesota | MR-visible medical device for neurological interventions using nonlinear magnetic stereotaxis and a method imaging |
| US6361759B1 (en) * | 1998-05-26 | 2002-03-26 | Wisconsin Alumni Research Foundation | MR signal-emitting coatings |
| US20010000801A1 (en) * | 1999-03-22 | 2001-05-03 | Miller Paul J. | Hydrophilic sleeve |
| JP3753887B2 (ja) * | 1999-03-31 | 2006-03-08 | テルモ株式会社 | 体腔内病変部治療用器具 |
| US6368658B1 (en) * | 1999-04-19 | 2002-04-09 | Scimed Life Systems, Inc. | Coating medical devices using air suspension |
| JP4700173B2 (ja) * | 1999-07-16 | 2011-06-15 | テルモ株式会社 | カテーテルの製造方法およびカテーテル |
| JP4301670B2 (ja) * | 2000-01-12 | 2009-07-22 | テルモ株式会社 | 医療用チューブ |
| FR2808026B1 (fr) * | 2000-04-25 | 2002-06-14 | Alexandre Laurent | Biomateriau a base de polymere hydrophile presentant un signal specifique en imagerie par resonance magnetique et procede de preparation d'un tel biomateriau |
| AU2001253591B2 (en) * | 2000-09-11 | 2006-09-07 | Union Carbide Chemicals & Plastics Technology Corporation | Hydrophilic, lubricious medical devices having contrast for magnetic resonance imaging |
| DE10057038A1 (de) * | 2000-11-17 | 2002-05-29 | Rehau Ag & Co | Medizinische Arbeitsmittel |
| US6911017B2 (en) * | 2001-09-19 | 2005-06-28 | Advanced Cardiovascular Systems, Inc. | MRI visible catheter balloon |
| US20030100829A1 (en) * | 2001-11-27 | 2003-05-29 | Sheng-Ping Zhong | Medical devices with magnetic resonance visibility enhancing material |
-
2001
- 2001-11-27 US US09/995,528 patent/US20030100829A1/en not_active Abandoned
-
2002
- 2002-09-05 DE DE60232190T patent/DE60232190D1/de not_active Expired - Lifetime
- 2002-09-05 CA CA002468105A patent/CA2468105A1/en not_active Abandoned
- 2002-09-05 AU AU2002332847A patent/AU2002332847A1/en not_active Abandoned
- 2002-09-05 WO PCT/US2002/028202 patent/WO2003045462A1/en not_active Ceased
- 2002-09-05 AT AT02803959T patent/ATE429939T1/de not_active IP Right Cessation
- 2002-09-05 EP EP02803959A patent/EP1465682B1/en not_active Expired - Lifetime
- 2002-09-05 JP JP2003546961A patent/JP4790215B2/ja not_active Expired - Fee Related
- 2002-09-05 ES ES02803959T patent/ES2326162T3/es not_active Expired - Lifetime
-
2005
- 2005-06-13 US US11/151,044 patent/US20050255046A1/en not_active Abandoned
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