JP2005530819A5 - - Google Patents
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- Publication number
- JP2005530819A5 JP2005530819A5 JP2004512660A JP2004512660A JP2005530819A5 JP 2005530819 A5 JP2005530819 A5 JP 2005530819A5 JP 2004512660 A JP2004512660 A JP 2004512660A JP 2004512660 A JP2004512660 A JP 2004512660A JP 2005530819 A5 JP2005530819 A5 JP 2005530819A5
- Authority
- JP
- Japan
- Prior art keywords
- bone
- composition
- composition according
- growth
- treatment comprises
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37789802P | 2002-05-02 | 2002-05-02 | |
| PCT/US2003/013696 WO2003105752A2 (en) | 2002-05-02 | 2003-05-02 | Methods and compositions for stimulating bone growth using nitric oxide releasing bisphosphonate conjugates (no-bisphosphonate) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005530819A JP2005530819A (ja) | 2005-10-13 |
| JP2005530819A5 true JP2005530819A5 (enExample) | 2006-06-22 |
Family
ID=29736069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004512660A Pending JP2005530819A (ja) | 2002-05-02 | 2003-05-02 | 一酸化窒素を放出するビスホスホネート結合体（ｎｏ−ビスホスホネート）を使用して骨増殖を刺激するための、方法および組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7288535B2 (enExample) |
| EP (1) | EP1539185A4 (enExample) |
| JP (1) | JP2005530819A (enExample) |
| AU (1) | AU2003231255A1 (enExample) |
| CA (1) | CA2485090A1 (enExample) |
| WO (1) | WO2003105752A2 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6376476B1 (en) * | 1996-12-13 | 2002-04-23 | Zymogenetics Corporation | Isoprenoid pathway inhibitors for stimulating bone growth |
| US7473678B2 (en) | 2004-10-14 | 2009-01-06 | Biomimetic Therapeutics, Inc. | Platelet-derived growth factor compositions and methods of use thereof |
| US8071574B2 (en) * | 2005-02-22 | 2011-12-06 | John Dennis Bobyn | Implant improving local bone formation |
| WO2007061889A2 (en) * | 2005-11-17 | 2007-05-31 | Biomimetic Therapeutics, Inc. | Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix |
| ES2427993T3 (es) * | 2006-02-09 | 2013-11-05 | Biomimetic Therapeutics, Llc | Composiciones y métodos para el tratamiento de hueso |
| US9161967B2 (en) * | 2006-06-30 | 2015-10-20 | Biomimetic Therapeutics, Llc | Compositions and methods for treating the vertebral column |
| WO2008005427A2 (en) | 2006-06-30 | 2008-01-10 | Biomimetic Therapeutics, Inc. | Pdgf-biomatrix compositions and methods for treating rotator cuff injuries |
| EP2462895B1 (en) | 2006-11-03 | 2016-11-02 | BioMimetic Therapeutics, LLC | Compositions and methods for arthrodetic procedures |
| CA2715254A1 (en) * | 2008-02-07 | 2009-08-13 | Biomimetic Therapeutics, Inc. | Compositions and methods for distraction osteogenesis |
| CN102231992B (zh) * | 2008-09-09 | 2015-05-20 | 生物模拟治疗公司 | 用于治疗肌腱和韧带损伤的血小板衍生生长因子的组合物和方法 |
| JP2012519556A (ja) * | 2009-03-05 | 2012-08-30 | バイオミメティック セラピューティクス， インコーポレイテッド | 骨軟骨欠損を治療するための血小板由来増殖因子組成物および方法 |
| US8936804B2 (en) | 2010-01-15 | 2015-01-20 | Rutgers, The State University Of New Jersey | Use of vanadium compounds to accelerate bone healing |
| BR112012020566B1 (pt) | 2010-02-22 | 2021-09-21 | Biomimetic Therapeutics, Llc | Composição de fator de crescimento derivado de plaqueta |
| US8877221B2 (en) | 2010-10-27 | 2014-11-04 | Warsaw Orthopedic, Inc. | Osteoconductive matrices comprising calcium phosphate particles and statins and methods of using the same |
| US9107983B2 (en) | 2010-10-27 | 2015-08-18 | Warsaw Orthopedic, Inc. | Osteoconductive matrices comprising statins |
| BR112013014177A2 (pt) | 2010-12-10 | 2016-07-12 | Univ New Jersey Med | dispositivo de implante revestido com composto e seus métodos |
| US20140322292A1 (en) * | 2010-12-10 | 2014-10-30 | Rutgers, The State University Of New Jersey | Insulin-mimetics as therapeutic adjuncts for bone regeneration |
| WO2013006798A1 (en) | 2011-07-06 | 2013-01-10 | University Of Medicine And Dentistry Of New Jersey | Vandium compounds as therapeutic adjuncts for cartilage regeneration and repair |
| WO2012170417A2 (en) | 2011-06-06 | 2012-12-13 | Warsaw Orthopedic, Inc. | Methods and compositions to enhance bone growth comprising a statin |
| US20170087175A1 (en) * | 2015-09-30 | 2017-03-30 | Elwha Llc | Nitric oxide-modulating bone-targeting complexes |
| US20190275160A1 (en) | 2016-03-15 | 2019-09-12 | The Regents Of The University Of California | Bone-targeting therapeutic conjugate and methods of making and using the same |
| KR20180115979A (ko) | 2017-04-14 | 2018-10-24 | 연세대학교 산학협력단 | 비스포스포네이트를 포함하는 만성 이식신 기능부전 예방 또는 치료용 조성물 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5121253A (en) * | 1990-12-28 | 1992-06-09 | Waintroob Stewart B | Visor for a computer terminal display and method |
| IT1246778B (it) | 1991-04-12 | 1994-11-26 | Boehringer Mannheim Italia | Nitrosocarbamoil derivati di acidi gem-difosfonici, un processo per la loro preparazione e composizioni farmaceutiche che li contengono |
| US5118667A (en) * | 1991-05-03 | 1992-06-02 | Celtrix Pharmaceuticals, Inc. | Bone growth factors and inhibitors of bone resorption for promoting bone formation |
| US5280040A (en) | 1993-03-11 | 1994-01-18 | Zymogenetics, Inc. | Methods for reducing bone loss using centchroman derivatives |
| US5898038A (en) * | 1996-03-19 | 1999-04-27 | Board Of Regents, The University Of Texas System | Treatment of osteoporosis and metabolic bone disorders with nitric oxide substrate and/or donors |
| US6214812B1 (en) * | 1998-04-02 | 2001-04-10 | Mbc Research, Inc. | Bisphosphonate conjugates and methods of making and using the same |
| IT1303672B1 (it) | 1998-07-28 | 2001-02-23 | Nicox Sa | Sali nitrati di farmaci attivi nei disordini ossei |
| US6121253A (en) * | 1998-11-20 | 2000-09-19 | Merck Frosst Canada & Co. | Prostaglandin conjugates for treating or preventing bone disease |
| WO2000051597A1 (en) | 1999-03-05 | 2000-09-08 | Merck Frosst Canada & Co. | Methods for inhibiting cathepsin k activity for the treatment of diseases related to bone loss |
| IT1311924B1 (it) | 1999-04-13 | 2002-03-20 | Nicox Sa | Composti farmaceutici. |
| IT1314184B1 (it) * | 1999-08-12 | 2002-12-06 | Nicox Sa | Composizioni farmaceutiche per la terapia di condizioni di stressossidativo |
-
2003
- 2003-05-02 EP EP03724391A patent/EP1539185A4/en not_active Withdrawn
- 2003-05-02 JP JP2004512660A patent/JP2005530819A/ja active Pending
- 2003-05-02 AU AU2003231255A patent/AU2003231255A1/en not_active Abandoned
- 2003-05-02 CA CA002485090A patent/CA2485090A1/en not_active Abandoned
- 2003-05-02 WO PCT/US2003/013696 patent/WO2003105752A2/en not_active Ceased
- 2003-05-02 US US10/428,309 patent/US7288535B2/en not_active Expired - Fee Related
-
2007
- 2007-10-30 US US11/929,701 patent/US20080108588A1/en not_active Abandoned
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