JP2002529490A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2002529490A5 JP2002529490A5 JP2000582002A JP2000582002A JP2002529490A5 JP 2002529490 A5 JP2002529490 A5 JP 2002529490A5 JP 2000582002 A JP2000582002 A JP 2000582002A JP 2000582002 A JP2000582002 A JP 2000582002A JP 2002529490 A5 JP2002529490 A5 JP 2002529490A5
- Authority
- JP
- Japan
- Prior art keywords
- bisphosphonate
- pharmaceutically acceptable
- acceptable salt
- substituted
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10857698P | 1998-11-16 | 1998-11-16 | |
| US60/108,576 | 1998-11-16 | ||
| PCT/US1999/026719 WO2000028954A1 (en) | 1998-11-16 | 1999-11-12 | Method for inhibiting dental resorptive lesions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002529490A JP2002529490A (ja) | 2002-09-10 |
| JP2002529490A5 true JP2002529490A5 (enExample) | 2007-01-11 |
Family
ID=22322969
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000582002A Pending JP2002529490A (ja) | 1998-11-16 | 1999-11-12 | 歯牙吸収性病変の阻害方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6331533B1 (enExample) |
| EP (1) | EP1133273A4 (enExample) |
| JP (1) | JP2002529490A (enExample) |
| AU (1) | AU761157B2 (enExample) |
| CA (1) | CA2351617C (enExample) |
| WO (1) | WO2000028954A1 (enExample) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1232751A1 (en) * | 1999-11-25 | 2002-08-21 | Yamanouchi Pharmaceutical Co. Ltd. | Remedies for periodontosis |
| US6638920B2 (en) | 2000-07-21 | 2003-10-28 | Merck & Co., Inc. | Compositions and methods of preventing or reducing the risk or incidence of skeletal injuries in horses |
| GB0029111D0 (en) * | 2000-11-29 | 2001-01-10 | Novartis Ag | Organic compounds |
| US6491896B1 (en) * | 2001-03-19 | 2002-12-10 | The Proctor & Gamble Company | Polybutene containing denture cleanser compositions |
| US20050070504A1 (en) * | 2001-12-21 | 2005-03-31 | The Procter & Gamble Co. | Risedronate compositions and their methods of use |
| FR2838339B1 (fr) * | 2002-04-12 | 2005-06-24 | Univ Angers | Derives poly-phosphonates pour compositions dentifrices |
| CA2763775C (en) * | 2002-05-10 | 2014-01-07 | F. Hoffmann-La Roche Ag | Bisphosphonic acids for the treatment and prevention of osteoporosis |
| WO2006019843A1 (en) * | 2004-07-15 | 2006-02-23 | Nanobac Life Sciences | Methods and compositions for the administration of calcium chelators, bisphosphonates and/or citrate compounds and their pharmaceutical uses |
| WO2009018834A1 (en) * | 2007-08-06 | 2009-02-12 | Pharmathen S.A. | Pharmaceutical composition containing bisphosphonate and method for the preparation thereof |
| US9949993B2 (en) | 2012-05-14 | 2018-04-24 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating low back pain |
| US10080765B2 (en) | 2012-05-14 | 2018-09-25 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
| US10016445B2 (en) | 2012-05-14 | 2018-07-10 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9867839B2 (en) | 2012-05-14 | 2018-01-16 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for joint conditions |
| US9827192B2 (en) | 2012-05-14 | 2017-11-28 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US10350227B2 (en) | 2012-05-14 | 2019-07-16 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
| US10016446B2 (en) | 2012-05-14 | 2018-07-10 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating Paget's disease of bone |
| US9827256B2 (en) | 2014-05-27 | 2017-11-28 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating lower back pain |
| US10413561B2 (en) | 2012-05-14 | 2019-09-17 | Antecip Bioventures Ii Llc | Neridronic acid and other bisphosphonates for treating complex regional pain syndrome and other diseases |
| US9925203B2 (en) | 2012-05-14 | 2018-03-27 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating low back pain |
| US10493085B2 (en) | 2012-05-14 | 2019-12-03 | Antecip Bioventures Ii Llc | Neridronic acid and other bisphosphonates for treating complex regional pain syndrome and other diseases |
| US9943531B2 (en) | 2014-08-08 | 2018-04-17 | Antecip Bioventures Ii Llc | Osteoclast inhibitors such as zoledronic acid for low back pain treatment |
| US9211257B2 (en) | 2012-05-14 | 2015-12-15 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for knee conditions |
| US10034890B2 (en) | 2012-05-14 | 2018-07-31 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9956234B2 (en) | 2012-05-14 | 2018-05-01 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for joint conditions |
| US10004756B2 (en) | 2014-05-15 | 2018-06-26 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9901589B2 (en) | 2012-05-14 | 2018-02-27 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US10413560B2 (en) | 2012-05-14 | 2019-09-17 | Antecip Bioventures Ii Llc | Dosage forms for oral administration of zoledronic acid or related compounds for treating disease |
| US10463682B2 (en) | 2012-05-14 | 2019-11-05 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating low back pain |
| US10173986B2 (en) | 2012-05-14 | 2019-01-08 | Antecip Bioventures Ii Llc | Methods for the safe administration of imidazole or imidazolium compounds |
| US10039773B2 (en) | 2012-05-14 | 2018-08-07 | Antecip Bioventures Ii Llc | Neridronic acid for treating arthritis |
| US10111837B2 (en) | 2012-05-14 | 2018-10-30 | Antecip Bioventures Ii Llc | Dosage forms for oral administration of zoledronic acid or related compounds |
| US9956237B2 (en) | 2012-05-14 | 2018-05-01 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for knee conditions |
| US11654152B2 (en) | 2012-05-14 | 2023-05-23 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating disease |
| US9956238B2 (en) | 2014-05-15 | 2018-05-01 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating low back pain |
| US9770457B2 (en) | 2012-05-14 | 2017-09-26 | Antecip Bioventures Ii Llc | Neridronic acid for treating bone marrow lesion |
| US9999628B2 (en) | 2012-05-14 | 2018-06-19 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
| US9999629B2 (en) | 2012-05-14 | 2018-06-19 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9861648B2 (en) | 2012-05-14 | 2018-01-09 | Antecip Boiventures Ii Llc | Osteoclast inhibitors for knee conditions |
| US10028969B2 (en) | 2012-05-14 | 2018-07-24 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9895383B2 (en) | 2012-05-14 | 2018-02-20 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9820999B2 (en) | 2012-05-14 | 2017-11-21 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
| US10028908B2 (en) | 2012-05-14 | 2018-07-24 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US10092581B2 (en) | 2014-05-15 | 2018-10-09 | Antecip Bioventures Ii Llc | Osteoclast inhibitors such as zoledronic acid for low back pain treatment |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1201087B (it) | 1982-04-15 | 1989-01-27 | Gentili Ist Spa | Bifosfonati farmacologicamente attivi,procedimento per la loro preparazione e relative composizioni farmaceutiche |
| IT1196315B (it) | 1984-10-29 | 1988-11-16 | Gentili Ist Spa | Procedimento per la preparazione di acidi difosfonici |
| US4922007A (en) | 1989-06-09 | 1990-05-01 | Merck & Co., Inc. | Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or salts thereof |
| US5019651A (en) | 1990-06-20 | 1991-05-28 | Merck & Co., Inc. | Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid (ABP) or salts thereof |
| US5159108A (en) | 1990-09-18 | 1992-10-27 | Merck & Co., Inc. | Process for preparing an antihypercalcemic agent |
| US5270365A (en) | 1991-12-17 | 1993-12-14 | Merck & Co., Inc. | Prevention and treatment of periodontal disease with alendronate |
| US5409911A (en) | 1992-09-11 | 1995-04-25 | Merck & Co., Inc. | Prostaglandin analog for treating osteoporosis |
| US5358941A (en) | 1992-12-02 | 1994-10-25 | Merck & Co., Inc. | Dry mix formulation for bisphosphonic acids with lactose |
| FI92465C (fi) | 1993-04-14 | 1994-11-25 | Risto Tapani Lehtinen | Menetelmä endo-osteaalisten materiaalien käsittelemiseksi |
| TW257765B (enExample) | 1993-08-25 | 1995-09-21 | Merck & Co Inc | |
| US5510517A (en) | 1993-08-25 | 1996-04-23 | Merck & Co., Inc. | Process for producing N-amino-1-hydroxy-alkylidene-1,1-bisphosphonic acids |
| ATE202571T1 (de) | 1993-09-14 | 2001-07-15 | Merck & Co Inc | Humane protein-tyrosinphosphatase decodierende cdna |
| JPH09511927A (ja) * | 1994-04-18 | 1997-12-02 | ザ、プロクター、エンド、ギャンブル、カンパニー | 歯槽骨へのビスホスホネート類のイオン導入デリバリー |
| US5646134A (en) | 1994-04-21 | 1997-07-08 | Merck & Co., Inc. | Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices |
| US5462932A (en) | 1994-05-17 | 1995-10-31 | Merck & Co., Inc. | Oral liquid alendronate formulations |
| US5449819A (en) | 1994-06-06 | 1995-09-12 | Merck & Co., Inc. | Process for removing waste pox, alendronate and its by products |
| US5589691A (en) | 1994-06-06 | 1996-12-31 | Merck & Co., Inc. | Process for recovery and recycle of methanesulfonic acid and phosphorous acid |
| US5780455A (en) | 1994-08-24 | 1998-07-14 | Merck & Co., Inc. | Intravenous alendronate formulations |
| US6008206A (en) | 1994-09-21 | 1999-12-28 | Merck & Co., Inc. | Sodium alendronate preparation for local administration |
| JP3411690B2 (ja) | 1994-09-21 | 2003-06-03 | 帝人株式会社 | 局所投与用アレンドロン酸ナトリウム製剤 |
| GB2294879A (en) | 1994-10-19 | 1996-05-15 | Merck & Co Inc | Cylcooxygenase-2 Inhibitors |
| US5652227A (en) | 1995-01-30 | 1997-07-29 | Teronen; Olli Pekka | Inhibition of the degradation of connective tissue matrix protein components in mammals |
| JPH10504839A (ja) | 1995-02-17 | 1998-05-12 | メルク エンド カンパニー インコーポレーテッド | 非脊椎骨折のリスクを減少させる方法 |
| CA2219354A1 (en) | 1995-05-12 | 1996-11-14 | Merck & Co., Inc. | Prevention of tooth loss by the administration of alendronate or its salts |
| US5616571A (en) | 1995-06-06 | 1997-04-01 | Merck & Co., Inc. | Bisphosphonates prevent bone loss associated with immunosuppressive therapy |
| AU5886096A (en) | 1995-06-06 | 1996-12-24 | Merck & Co., Inc. | Anhydrous alendronate monosodium salt formulations |
| US5853759A (en) | 1996-05-17 | 1998-12-29 | Merck & Co.. Inc. | Effervescent alendronate formulation |
| US5994329A (en) | 1997-07-22 | 1999-11-30 | Merck & Co., Inc. | Method for inhibiting bone resorption |
| US6015801A (en) | 1997-07-22 | 2000-01-18 | Merck & Co., Inc. | Method for inhibiting bone resorption |
| US6008207A (en) | 1998-08-13 | 1999-12-28 | Merck & Co., Inc. | Anhydrous alendronate monosodium salt formulations |
| US5998390A (en) | 1998-09-28 | 1999-12-07 | The Research Foundation Of State University Of New York | Combination of bisphosphonate and tetracycline |
-
1999
- 1999-11-09 US US09/436,585 patent/US6331533B1/en not_active Expired - Lifetime
- 1999-11-12 JP JP2000582002A patent/JP2002529490A/ja active Pending
- 1999-11-12 AU AU18176/00A patent/AU761157B2/en not_active Expired
- 1999-11-12 EP EP99961646A patent/EP1133273A4/en not_active Withdrawn
- 1999-11-12 WO PCT/US1999/026719 patent/WO2000028954A1/en not_active Ceased
- 1999-11-12 CA CA002351617A patent/CA2351617C/en not_active Expired - Lifetime
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2002529490A5 (enExample) | ||
| CA2763775C (en) | Bisphosphonic acids for the treatment and prevention of osteoporosis | |
| CA2438848A1 (en) | Compositions for delivering bisphosphonates | |
| NZ545804A (en) | Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-or-vitamin D derivatives and a bisphosphonate | |
| RU2002121643A (ru) | Фармацевтическая парентеральная композиция, содержащая бифосфонат | |
| CA2410201A1 (en) | Zoledronic acid or salts thereof for use in the treatment of conditions of abnormally increased bone turnover | |
| JP2004528303A5 (enExample) | ||
| RU2003133773A (ru) | Фармацевтическое применение бисфосфонатов | |
| RU2006110736A (ru) | Комбинация, содержащая n-(3-метокси-5-метилпиразин-2-ил)-2-(1, 3, 4-оксадиазол-2-ил)пиридин-3-сульфонамид и lhrh- аналог и/или бифосфонат | |
| HUT68788A (en) | Composition for treating periodontal disease | |
| HRP20020594A2 (en) | Pharmaceutical parenteral composition containing a biphosphonate | |
| RU2006140888A (ru) | Лекарственные формы на основе бисфосфонатов | |
| JP2005530819A5 (enExample) | ||
| ES2269014T1 (es) | Procedimiento para inhibir la resorcion osea. | |
| JP2006500401A5 (enExample) | ||
| KR970705400A (ko) | 골 활성 포스포네이트 및 부갑상선 호르몬을 사용한 골다공증의 치료방법(methods for the treatment of osteoporosis using bone active phosphonates and parathyroid hormone) | |
| RU2003100503A (ru) | Способ введения бисфосфонатов | |
| KR970705399A (ko) | 골다공증용 포스포네이트 및 부갑상성 호르몬(phosphonates and parathyroid hormone for osteoporosis) | |
| AU2012202489B2 (en) | Bisphosphonic acid for the treatment and prevention of osteoporosis | |
| HK1104919A (en) | Bisphosphonic acid for the treatment and prevention of osteoporosis | |
| HK1080409B (en) | Bisphosphonic acid for the treatment and prevention of osteoporosis |