JP2005530730A5 - - Google Patents

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Publication number
JP2005530730A5
JP2005530730A5 JP2003584041A JP2003584041A JP2005530730A5 JP 2005530730 A5 JP2005530730 A5 JP 2005530730A5 JP 2003584041 A JP2003584041 A JP 2003584041A JP 2003584041 A JP2003584041 A JP 2003584041A JP 2005530730 A5 JP2005530730 A5 JP 2005530730A5
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JP
Japan
Prior art keywords
alkyl
alkoxy
independently
amino
fully halogenated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2003584041A
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English (en)
Japanese (ja)
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JP2005530730A (ja
JP4578106B2 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2003/011094 external-priority patent/WO2003087085A1/en
Publication of JP2005530730A publication Critical patent/JP2005530730A/ja
Publication of JP2005530730A5 publication Critical patent/JP2005530730A5/ja
Application granted granted Critical
Publication of JP4578106B2 publication Critical patent/JP4578106B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2003584041A 2002-04-11 2003-04-10 サイトカインインヒビターとしてのヘテロ環式アミド誘導体 Expired - Lifetime JP4578106B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37167102P 2002-04-11 2002-04-11
PCT/US2003/011094 WO2003087085A1 (en) 2002-04-11 2003-04-10 Heterocyclic amide derivatives as cytokine inhibitors

Publications (3)

Publication Number Publication Date
JP2005530730A JP2005530730A (ja) 2005-10-13
JP2005530730A5 true JP2005530730A5 (https=) 2006-06-08
JP4578106B2 JP4578106B2 (ja) 2010-11-10

Family

ID=29250721

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003584041A Expired - Lifetime JP4578106B2 (ja) 2002-04-11 2003-04-10 サイトカインインヒビターとしてのヘテロ環式アミド誘導体

Country Status (9)

Country Link
US (1) US7550461B2 (https=)
EP (1) EP1497278B1 (https=)
JP (1) JP4578106B2 (https=)
AT (1) ATE469142T1 (https=)
AU (1) AU2003224923A1 (https=)
CA (1) CA2478232C (https=)
DE (1) DE60332717D1 (https=)
ES (1) ES2343787T3 (https=)
WO (1) WO2003087085A1 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE469142T1 (de) * 2002-04-11 2010-06-15 Boehringer Ingelheim Pharma Heterocyclische amid-derivate als cytokin- inhibitoren
US7078419B2 (en) * 2003-03-10 2006-07-18 Boehringer Ingelheim Pharmaceuticals, Inc. Cytokine inhibitors
EP1867646A1 (en) * 2004-05-03 2007-12-19 Boehringer Ingelheim Pharmaceuticals, Inc. Cytokine inhibitors
EP1745036A2 (en) 2004-05-03 2007-01-24 Boehringer Ingelheim Pharmaceuticals Inc. Cytokine inhibitors
ATE460410T1 (de) * 2004-08-25 2010-03-15 Boehringer Ingelheim Pharma 2-arylcarbamoyl-indole als zytokinhemmer
US7741479B2 (en) * 2004-12-07 2010-06-22 Locus Pharmaceuticals, Inc. Urea inhibitors of MAP kinases
US7612200B2 (en) * 2004-12-07 2009-11-03 Locus Pharmaceuticals, Inc. Inhibitors of protein kinases
EP1838690A2 (en) * 2004-12-21 2007-10-03 Devgen N.V. Compounds with kv4 ion channel activity
US8957070B2 (en) 2005-04-20 2015-02-17 Takeda Pharmaceutical Company Limited Glucokinase activator compounds, methods of activating glucokinase and methods of treating diabetes and obesity
US20070185098A1 (en) * 2006-01-04 2007-08-09 Locus Pharmaceuticals, Inc. Inhibitors of protein kinases
CA2722923C (en) 2008-04-29 2016-08-02 Boehringer Ingelheim International Gmbh Indazole compounds as ccr1 receptor antagonists
CA2722811C (en) * 2008-05-06 2016-07-05 Boehringer Ingelheim International Gmbh Pyrazole compounds as ccr1 antagonists
EP2161266A1 (en) * 2008-08-22 2010-03-10 EVOTEC Neurosciences GmbH Benzofuran derivatives as orexin receptor antagonists
NZ591115A (en) 2008-09-26 2012-10-26 Boehringer Ingelheim Int Azaindazole compounds as ccr1 receptor antagonists
PH12012500775A1 (en) 2009-10-21 2012-11-26 Boehringer Ingelheim Int Indazole and pyrazolopyridine compounds as ccr1 receptor antagonists
US8927550B2 (en) 2009-10-27 2015-01-06 Boehringer Ingelheim International Gmbh Heterocyclic compounds as CCR1 receptor antagonists
US8871786B2 (en) 2010-04-30 2014-10-28 Boehringer Ingelheim International Gmbh Azaindazole amide compounds as CCR1 receptor antagonists
WO2012087782A1 (en) 2010-12-23 2012-06-28 Boehringer Ingelheim International Gmbh Pyrazolopiperidine compounds as ccr1 receptor antagonists
CN117510460B (zh) * 2023-10-30 2026-02-06 贵州大学 一种含磺酰胺单元的苯并[b]噻吩衍生物、其制备方法及应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4317076A1 (de) * 1993-05-21 1994-11-24 Bayer Ag Benzthiophencarbonsäureamid-S-oxide
DE19642529A1 (de) * 1996-10-15 1998-04-16 Bayer Ag Aminophenolderivate
US5994398A (en) * 1996-12-11 1999-11-30 Elan Pharmaceuticals, Inc. Arylsulfonamides as phospholipase A2 inhibitors
PL195600B1 (pl) 1998-05-15 2007-10-31 Astrazeneca Ab Pochodne benzamidowe, sposób ich wytwarzania, zawierające je kompozycje farmaceutyczne oraz ich zastosowanie do wytwarzania leku do leczenia stanów medycznych powstających za pośrednictwem cytokin
ATE254105T1 (de) * 1998-09-25 2003-11-15 Astrazeneca Ab Benzamid-derivate und ihre verwendung als cytokine inhibitoren
ATE278674T1 (de) 1999-03-12 2004-10-15 Boehringer Ingelheim Pharma Heterocyklischer harnstoff und verwandte verbindungen als entzündungshemmende mittel
TWI290136B (en) * 2000-04-05 2007-11-21 Daiichi Seiyaku Co Ethylenediamine derivatives
EP1310488A4 (en) * 2000-08-09 2005-08-10 Mitsubishi Pharma Corp CONCENTRATED BICYCLIC AMID COMPOUNDS AND THEIR MEDICAL USE
WO2002083628A1 (en) * 2001-04-13 2002-10-24 Boehringer Ingelheim Pharmaceuticals, Inc. 1,4-disubstituted benzo-fused compounds
AR034897A1 (es) * 2001-08-07 2004-03-24 Hoffmann La Roche Derivados n-monoacilados de o-fenilendiaminas, sus analogos heterociclicos de seis miembros y su uso como agentes farmaceuticos
ATE469142T1 (de) * 2002-04-11 2010-06-15 Boehringer Ingelheim Pharma Heterocyclische amid-derivate als cytokin- inhibitoren

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