JP2005528332A5 - - Google Patents
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- Publication number
- JP2005528332A5 JP2005528332A5 JP2003550718A JP2003550718A JP2005528332A5 JP 2005528332 A5 JP2005528332 A5 JP 2005528332A5 JP 2003550718 A JP2003550718 A JP 2003550718A JP 2003550718 A JP2003550718 A JP 2003550718A JP 2005528332 A5 JP2005528332 A5 JP 2005528332A5
- Authority
- JP
- Japan
- Prior art keywords
- use according
- pharmaceutical composition
- mycobacterium
- component
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 17
- 241001494992 Mycobacterium indicus pranii Species 0.000 claims 16
- 230000000694 effects Effects 0.000 claims 6
- 206010028980 Neoplasm Diseases 0.000 claims 5
- 201000011510 cancer Diseases 0.000 claims 5
- 239000004094 surface-active agent Substances 0.000 claims 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 3
- 239000008280 blood Substances 0.000 claims 3
- 210000004369 blood Anatomy 0.000 claims 3
- 238000002512 chemotherapy Methods 0.000 claims 3
- 239000002552 dosage form Substances 0.000 claims 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 claims 3
- 238000002360 preparation method Methods 0.000 claims 3
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical group ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims 2
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims 2
- 239000003960 organic solvent Substances 0.000 claims 2
- 238000000053 physical method Methods 0.000 claims 2
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims 2
- 229920000053 polysorbate 80 Polymers 0.000 claims 2
- 238000001959 radiotherapy Methods 0.000 claims 2
- 229910002651 NO3 Inorganic materials 0.000 claims 1
- 206010028813 Nausea Diseases 0.000 claims 1
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims 1
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 claims 1
- 108010046334 Urease Proteins 0.000 claims 1
- 206010047700 Vomiting Diseases 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 208000007502 anemia Diseases 0.000 claims 1
- 239000004202 carbamide Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 238000000605 extraction Methods 0.000 claims 1
- 238000007918 intramuscular administration Methods 0.000 claims 1
- 230000003902 lesion Effects 0.000 claims 1
- 201000002364 leukopenia Diseases 0.000 claims 1
- 231100001022 leukopenia Toxicity 0.000 claims 1
- 230000001394 metastastic effect Effects 0.000 claims 1
- 206010061289 metastatic neoplasm Diseases 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 230000008693 nausea Effects 0.000 claims 1
- 229960003512 nicotinic acid Drugs 0.000 claims 1
- 235000001968 nicotinic acid Nutrition 0.000 claims 1
- 239000011664 nicotinic acid Substances 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- 230000002335 preservative effect Effects 0.000 claims 1
- 238000000527 sonication Methods 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
- 206010043554 thrombocytopenia Diseases 0.000 claims 1
- 230000008673 vomiting Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1167MU2001 | 2001-12-10 | ||
| PCT/IB2002/005516 WO2003049667A2 (en) | 2001-12-10 | 2002-12-10 | The method of treating cancer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005528332A JP2005528332A (ja) | 2005-09-22 |
| JP2005528332A5 true JP2005528332A5 (https=) | 2006-01-05 |
| JP4527979B2 JP4527979B2 (ja) | 2010-08-18 |
Family
ID=11097334
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003550718A Expired - Fee Related JP4527979B2 (ja) | 2001-12-10 | 2002-12-10 | 癌を治療する方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7972609B2 (https=) |
| JP (1) | JP4527979B2 (https=) |
| AP (1) | AP1896A (https=) |
| AU (1) | AU2002348738B2 (https=) |
| CA (1) | CA2469266C (https=) |
| GB (1) | GB2389532C (https=) |
| NZ (1) | NZ533417A (https=) |
| UA (1) | UA79952C2 (https=) |
| WO (1) | WO2003049667A2 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8048434B2 (en) * | 2005-04-25 | 2011-11-01 | Cadila Pharmaceuticals, Ltd. | Vaccine adjuvants |
| EA023046B1 (ru) * | 2006-11-23 | 2016-04-29 | Кадила Фармасьютикалз Лимитед | Применение инактивированной нагреванием micobacterium w для снижения индуцированной tlr активности |
| US20100104536A1 (en) * | 2007-03-20 | 2010-04-29 | Indravadan Ambalal Modi | P38 inhibitors |
| RU2010101164A (ru) * | 2007-06-28 | 2011-08-10 | Кадила Фармасьютикалз Лтд. (In) | Модулятор митоген-активируемой протеинкиназы |
| WO2011083493A1 (en) * | 2010-01-08 | 2011-07-14 | National Institute Of Immunology | Human chorionic gonadotropin (hcg) based vaccine for prevention and treatment of cancer |
| JP2013519723A (ja) * | 2010-02-19 | 2013-05-30 | カディラ ファーマシューティカルズ リミテッド | 実質的に保持された免疫原性を有する死細胞の薬学的組成物 |
| CN105943559A (zh) * | 2010-10-13 | 2016-09-21 | 特莱斯塔治疗知识产权公司 | 细菌核糖核酸细胞壁组合物及其制备和使用方法 |
| CN103338779B (zh) * | 2011-01-11 | 2015-12-23 | 卡帝拉药物有限公司 | 分枝杆菌w在制备治疗癌症药物中的用途 |
| TR201101874A2 (tr) * | 2011-02-25 | 2011-08-22 | Leyla A�An Nac�Ye | Yüzeyel mesane tümorü tedavisinde kullanılabilecek mycobacterıum(mikobakteri) brumae hücre duvarı ekstreleri. |
| RU2615346C2 (ru) * | 2011-02-28 | 2017-04-04 | Кадила Фармасьютикалз Лимитед | Терапевтическая вакцина против рака |
| ES2647768T3 (es) * | 2011-07-05 | 2017-12-26 | Cadila Pharmaceuticals Limited | Antígeno de cáncer |
| US20200368293A1 (en) * | 2018-01-18 | 2020-11-26 | Vedanta Biosciences, Inc. | Compositions and methods for the treatment of cancer |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5504005A (en) * | 1987-03-02 | 1996-04-02 | Albert Einstein College Of Medicine Of Yeshiva University | Recombinant mycobacterial vaccine |
| US6126945A (en) * | 1989-10-03 | 2000-10-03 | Pharmacia Ab | Tumor killing effects of enterotoxins, superantigens, and related compounds |
| IL105503A (en) * | 1992-04-28 | 1999-05-09 | Astra Ab | Carbon peptide couplets capable of eliciting an immune response of T cells |
| GB9223816D0 (en) * | 1992-11-13 | 1993-01-06 | Medical Res Council | Heat shock proteins and the treatment of tumours |
| US5767156A (en) * | 1993-10-06 | 1998-06-16 | Peptide Technology Limited | Polyunsaturated fatty acids and uses thereof |
| US6090385A (en) * | 1993-12-10 | 2000-07-18 | Maes; Hubert | Method of treating cancer |
| GB9406301D0 (en) * | 1994-03-30 | 1994-05-25 | Univ London | Immunotherapeutic agent and its use |
| US6056964A (en) * | 1995-03-29 | 2000-05-02 | Stanford Rook Limited | Immunotherapeutic agent and its use |
| US5935576A (en) * | 1995-09-13 | 1999-08-10 | Fordham University | Compositions and methods for the treatment and prevention of neoplastic diseases using heat shock proteins complexed with exogenous antigens |
| US6080725A (en) * | 1997-05-20 | 2000-06-27 | Galenica Pharmaceuticals, Inc. | Immunostimulating and vaccine compositions employing saponin analog adjuvants and uses thereof |
| US5869645A (en) * | 1997-10-15 | 1999-02-09 | Board Of Trustees Of The University Of Illinois | Method for isolating high molecular weight antineoplastic glycans using urea |
| AUPP437698A0 (en) * | 1998-06-30 | 1998-07-23 | Baumgart, Karl | Methods for treatment of coronary, carotid and other vascular disease |
| KR20050008453A (ko) * | 2002-03-08 | 2005-01-21 | 바쿠레시 마파탈 카마르 | 결핵 관리에 유용한 약제학적 조성물의 제조방법 |
-
2002
- 2002-10-12 UA UA20040705575A patent/UA79952C2/uk unknown
- 2002-12-10 AU AU2002348738A patent/AU2002348738B2/en not_active Ceased
- 2002-12-10 GB GB0322773A patent/GB2389532C/en not_active Expired - Fee Related
- 2002-12-10 AP APAP/P/2004/003070A patent/AP1896A/en active
- 2002-12-10 US US10/502,417 patent/US7972609B2/en not_active Expired - Fee Related
- 2002-12-10 WO PCT/IB2002/005516 patent/WO2003049667A2/en not_active Ceased
- 2002-12-10 NZ NZ533417A patent/NZ533417A/en not_active IP Right Cessation
- 2002-12-10 CA CA2469266A patent/CA2469266C/en not_active Expired - Fee Related
- 2002-12-10 JP JP2003550718A patent/JP4527979B2/ja not_active Expired - Fee Related
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