JP2005527512A - アルツハイマー病の治療および認知増強のための方法 - Google Patents

アルツハイマー病の治療および認知増強のための方法 Download PDF

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JP2005527512A
JP2005527512A JP2003574126A JP2003574126A JP2005527512A JP 2005527512 A JP2005527512 A JP 2005527512A JP 2003574126 A JP2003574126 A JP 2003574126A JP 2003574126 A JP2003574126 A JP 2003574126A JP 2005527512 A JP2005527512 A JP 2005527512A
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bryostatin
disease
pkc
alzheimer
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エッチェベッリガレイ、レネ
アルコン、ダニエル・エル
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ブランシェット・ロックフェラー・ニューロサイエンスィズ・インスティテュート
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JP2003574126A 2002-03-07 2003-03-07 アルツハイマー病の治療および認知増強のための方法 Withdrawn JP2005527512A (ja)

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US36208002P 2002-03-07 2002-03-07
US10/167,491 US6825229B2 (en) 2002-03-07 2002-06-13 Methods for Alzheimer's Disease treatment and cognitive enhancement
PCT/US2003/007101 WO2003075850A2 (en) 2002-03-07 2003-03-07 Methods for alzheimer's disease treatment and cognitive enhancement

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JP2005527512A true JP2005527512A (ja) 2005-09-15
JP2005527512A5 JP2005527512A5 (enExample) 2006-06-15

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EP (2) EP1490050B1 (enExample)
JP (1) JP2005527512A (enExample)
AU (1) AU2003220096A1 (enExample)
CA (1) CA2477973A1 (enExample)
ES (1) ES2639578T3 (enExample)
WO (1) WO2003075850A2 (enExample)

Cited By (6)

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WO2008016107A1 (en) * 2006-08-04 2008-02-07 Toyama Chemical Co., Ltd. Protein kinase c activity enhancer containing alkyl ether derivative or salt thereof
JP2010521124A (ja) * 2007-03-09 2010-06-17 クゥアルコム・インコーポレイテッド 不偏トレーニングシーケンスを使用した直交不平衡緩和
JP2013100308A (ja) * 2004-09-10 2013-05-23 Blanchette Rockefeller Neurosciences Inst アルツハイマー病の治療および認知の向上のための方法
JP2016101163A (ja) * 2010-02-22 2016-06-02 ブランシェット・ロックフェラー・ニューロサイエンスィズ・インスティテュート プロテインキナーゼｃイプシロン（ｐｋｃ−イプシロン）タンパク質レベルの、アルツハイマー病に特異的な変化
JP2016516201A (ja) * 2013-03-15 2016-06-02 ブランシェット・ロックフェラー・ニューロサイエンスィズ・インスティテュート 神経保護性ｐｋｃ活性化因子を特定する方法
JP2018521113A (ja) * 2015-05-11 2018-08-02 アルコン、ダニエル・エル． ＡｐｏＥ４対立遺伝子の存在を決定した後のＰＫＣ活性化因子を使用した神経変性状態の治療

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US20080004332A1 (en) * 2002-03-07 2008-01-03 Alkon Daniel L Methods for alzheimer's disease treatment and cognitive enhancement
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KR20130122630A (ko) 2005-07-29 2013-11-07 블랜체트 록펠러 뉴로사이언시즈 인스티튜트 단독의 또는 ｐｋｃ 억제제와 배합된 ｐｋｃ 활성화제의 장기 기억 향상을 위한 용도
WO2007044094A1 (en) * 2005-10-11 2007-04-19 Blanchette Rockefeller Neurosciences Institute Alzheimer's disease-specific alterations of the erk1/erk2 phosphorylation ratio as alzheimer's disease-specific molecular biomarkers (adsmb)
EP2762136A1 (en) * 2006-07-28 2014-08-06 Blanchette Rockefeller Neurosciences, Institute Methods of stimulating cellular growth, synaptic remodeling and consolidation of long-term memory
US20170319541A9 (en) * 2006-07-28 2017-11-09 Blanchette Rockefeller Neuroscience Institute Methods of stimulating cellular growth, synaptic remodeling and consolidation of long-term memory
EP3332797A3 (en) * 2007-02-09 2018-08-01 Blanchette Rockefeller Neurosciences Institute Therapeutic effects of bryostatins, bryologs and other related substances on head trauma-induced memory impairment and brain injury
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WO2009099563A2 (en) * 2008-02-05 2009-08-13 Blanchette Rockefeller Neurosciences Institute Combination of a nmda receptor channel blocker and a pkc activator for treatment of alzheimer's disease
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US9107890B2 (en) 2010-07-08 2015-08-18 Blanchette Rockefeller Neurosciences Institute PKC activators and anticoagulant in regimen for treating stroke
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US9446020B2 (en) 2016-09-20
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