JP2005527510A - 癌の治療において一酸化窒素模倣体を使用するための製剤および方法 - Google Patents
癌の治療において一酸化窒素模倣体を使用するための製剤および方法 Download PDFInfo
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- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
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| PCT/CA2003/000313 WO2003074082A1 (en) | 2002-03-06 | 2003-03-06 | Formulations and methods of using nitric oxide mimetics in cancer treatment |
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| AU (1) | AU2003208228A1 (https=) |
| CA (1) | CA2478145A1 (https=) |
| WO (1) | WO2003074082A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2009242378A (ja) * | 2008-03-13 | 2009-10-22 | Chiba Univ | シスプラチン効果増強剤及び抗癌剤キット |
| JP2011507968A (ja) * | 2007-12-27 | 2011-03-10 | エイヤーズ ファーマシューティカルズ、インク． | エアロゾル化ニトライトおよび一酸化窒素供与性化合物ならびにそれらの使用 |
| JP2011521908A (ja) * | 2008-05-09 | 2011-07-28 | デューク ユニバーシティ | チオレドキシンが細胞における一酸化窒素放出を調節するという知見に基づく疾患の治療法 |
| WO2012118042A1 (ja) * | 2011-02-28 | 2012-09-07 | 独立行政法人国立循環器病研究センター | 悪性腫瘍転移抑制用医薬 |
| JP2012219050A (ja) * | 2011-04-07 | 2012-11-12 | Nipro Corp | 抗癌剤増感剤 |
| JP2017515800A (ja) * | 2014-04-08 | 2017-06-15 | ザ・メソジスト・ホスピタル | ｉＮＯＳ阻害組成物および乳がん治療薬としてのその使用 |
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| DE10135815A1 (de) * | 2001-07-23 | 2003-02-06 | Bayer Ag | Verwendung von 2-Alkoxyphenyl-substituierten Imidazotriazinonen |
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| ATE438403T1 (de) * | 2004-08-19 | 2009-08-15 | Switch Biotech Llc | Verwendung eines pde5-hemmers zur behandlung und vorbeugung von hypopigmentierungsstörungen |
| AU2012203798B2 (en) * | 2005-08-12 | 2013-11-07 | Northrop Grumman Systems Corporation | O-nitro compounds, pharmaceutical compositons thereof and uses thereof |
| US20070135380A1 (en) | 2005-08-12 | 2007-06-14 | Radiorx, Inc. | O-nitro compounds, pharmaceutical compositions thereof and uses thereof |
| JP6055779B2 (ja) | 2010-12-27 | 2016-12-27 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | ナトリウム利尿ペプチドを含む組成物およびその使用方法 |
| US10052366B2 (en) | 2012-05-21 | 2018-08-21 | Alexion Pharmaceuticsl, Inc. | Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof |
| US10822596B2 (en) | 2014-07-11 | 2020-11-03 | Alexion Pharmaceuticals, Inc. | Compositions and methods for treating craniosynostosis |
| JP6787894B2 (ja) | 2014-12-05 | 2020-11-18 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | 組換えアルカリホスファターゼを用いた発作の処置 |
| JP6868561B2 (ja) | 2015-01-28 | 2021-05-12 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | アルカリホスファターゼ欠損を有する被験者を治療する方法 |
| JP6993961B2 (ja) | 2015-08-17 | 2022-01-14 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | アルカリホスファターゼの製造 |
| EP3355904A4 (en) | 2015-09-28 | 2019-06-12 | Alexion Pharmaceuticals, Inc. | IDENTIFICATION OF EFFECTIVE DOSE SHEETS FOR TISSUE-SPECIFIC ALKALINE PHOSPHATASE ENZYMERSAT THERAPY OF HYPOPHOSPHATASIA |
| WO2017074466A1 (en) | 2015-10-30 | 2017-05-04 | Alexion Pharmaceuticals, Inc. | Methods for treating craniosynostosis in a patient |
| WO2017155569A1 (en) | 2016-03-08 | 2017-09-14 | Alexion Pharmaceuticals, Inc. | Methods for treating hypophosphatasia in children |
| KR20240160671A (ko) | 2016-04-01 | 2024-11-11 | 알렉시온 파마슈티칼스, 인코포레이티드 | 알칼리성 포스파타아제로 근육 약화의 치료 |
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| US11913039B2 (en) | 2018-03-30 | 2024-02-27 | Alexion Pharmaceuticals, Inc. | Method for producing recombinant alkaline phosphatase |
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| KR20220111693A (ko) | 2019-12-09 | 2022-08-09 | 알렉시온 파마슈티칼스, 인코포레이티드 | 알칼리성 포스파타제 폴리펩티드 및 이의 이용 방법 |
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| CN114869894A (zh) * | 2022-05-10 | 2022-08-09 | 福州大学 | 一种小分子化合物在制备作为尿激酶受体抑制剂药物中的应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LV11542B (en) * | 1995-03-30 | 1997-02-20 | Latvijas Organiskas Sintezes Instituts | Substituted 1,3,9,11-tetraoxa-4,5,7,8-tetraazaundecadien-4,7-dioxides-5,7, preparation and use thereof |
| AU8398398A (en) * | 1997-07-14 | 1999-02-10 | Brigham And Women's Hospital | Modification of nitric oxide activity to treat fas-induced pathologies |
| JP2004508279A (ja) * | 2000-01-26 | 2004-03-18 | シーダース シナイ メディカル センター | 薬剤を異常脳領域及び／又は悪性腫瘍にデリバリーするためにカリウムチャンネル活性化を用いる方法 |
| US20010038832A1 (en) * | 2000-04-11 | 2001-11-08 | Benjamin Bonavida | Nitric oxide and analogues thereof effectuate sensitization of neoplasm and immunologically undesired tissues to cytotoxicity |
| JP2003531179A (ja) * | 2000-04-26 | 2003-10-21 | クイーンズ ユニバーシティ アット キングストン | 悪性細胞表現型に対し一酸化窒素模倣体を使用する処方および方法 |
-
2003
- 2003-03-06 JP JP2003572598A patent/JP2005527510A/ja active Pending
- 2003-03-06 AU AU2003208228A patent/AU2003208228A1/en not_active Abandoned
- 2003-03-06 WO PCT/CA2003/000313 patent/WO2003074082A1/en not_active Ceased
- 2003-03-06 EP EP03706181A patent/EP1492567A1/en not_active Withdrawn
- 2003-03-06 CA CA002478145A patent/CA2478145A1/en not_active Abandoned
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011507968A (ja) * | 2007-12-27 | 2011-03-10 | エイヤーズ ファーマシューティカルズ、インク． | エアロゾル化ニトライトおよび一酸化窒素供与性化合物ならびにそれらの使用 |
| JP2009242378A (ja) * | 2008-03-13 | 2009-10-22 | Chiba Univ | シスプラチン効果増強剤及び抗癌剤キット |
| JP2011521908A (ja) * | 2008-05-09 | 2011-07-28 | デューク ユニバーシティ | チオレドキシンが細胞における一酸化窒素放出を調節するという知見に基づく疾患の治療法 |
| WO2012118042A1 (ja) * | 2011-02-28 | 2012-09-07 | 独立行政法人国立循環器病研究センター | 悪性腫瘍転移抑制用医薬 |
| JP5948683B2 (ja) * | 2011-02-28 | 2016-07-06 | 国立研究開発法人国立循環器病研究センター | 悪性腫瘍転移抑制用医薬 |
| JP2012219050A (ja) * | 2011-04-07 | 2012-11-12 | Nipro Corp | 抗癌剤増感剤 |
| JP2017515800A (ja) * | 2014-04-08 | 2017-06-15 | ザ・メソジスト・ホスピタル | ｉＮＯＳ阻害組成物および乳がん治療薬としてのその使用 |
| US10420838B2 (en) | 2014-04-08 | 2019-09-24 | The Methodist Hospital | Methods for treating cancer using iNOS-inhibitory compositions |
| JP2020128445A (ja) * | 2014-04-08 | 2020-08-27 | ザ・メソジスト・ホスピタル | ｉＮＯＳ阻害組成物および乳がん治療薬としてのその使用 |
| US11357850B2 (en) | 2014-04-08 | 2022-06-14 | The Methodist Hospital | Methods for treating breast cancer using INOS-inhibitory compositions |
| JP2024128025A (ja) * | 2014-04-08 | 2024-09-20 | ザ・メソジスト・ホスピタル | ｉＮＯＳ阻害組成物および乳がん治療薬としてのその使用 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003074082A1 (en) | 2003-09-12 |
| AU2003208228A1 (en) | 2003-09-16 |
| EP1492567A1 (en) | 2005-01-05 |
| CA2478145A1 (en) | 2003-09-12 |
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