JP2005527510A - 癌の治療において一酸化窒素模倣体を使用するための製剤および方法 - Google Patents
癌の治療において一酸化窒素模倣体を使用するための製剤および方法 Download PDFInfo
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- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
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| PCT/CA2003/000313 WO2003074082A1 (en) | 2002-03-06 | 2003-03-06 | Formulations and methods of using nitric oxide mimetics in cancer treatment |
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| JP2009242378A (ja) * | 2008-03-13 | 2009-10-22 | Chiba Univ | シスプラチン効果増強剤及び抗癌剤キット |
| JP2011507968A (ja) * | 2007-12-27 | 2011-03-10 | エイヤーズ ファーマシューティカルズ、インク． | エアロゾル化ニトライトおよび一酸化窒素供与性化合物ならびにそれらの使用 |
| JP2011521908A (ja) * | 2008-05-09 | 2011-07-28 | デューク ユニバーシティ | チオレドキシンが細胞における一酸化窒素放出を調節するという知見に基づく疾患の治療法 |
| WO2012118042A1 (ja) * | 2011-02-28 | 2012-09-07 | 独立行政法人国立循環器病研究センター | 悪性腫瘍転移抑制用医薬 |
| JP2012219050A (ja) * | 2011-04-07 | 2012-11-12 | Nipro Corp | 抗癌剤増感剤 |
| JP2017515800A (ja) * | 2014-04-08 | 2017-06-15 | ザ・メソジスト・ホスピタル | ｉＮＯＳ阻害組成物および乳がん治療薬としてのその使用 |
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| DE10135815A1 (de) * | 2001-07-23 | 2003-02-06 | Bayer Ag | Verwendung von 2-Alkoxyphenyl-substituierten Imidazotriazinonen |
| CA2559228C (en) | 2004-04-21 | 2016-06-21 | Enobia Pharma Inc. | Bone delivery conjugates and method of using same to target proteins to bone |
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| EP1759700B1 (en) * | 2004-08-19 | 2009-08-05 | Switch Biotech, LLC | Use of a PDE5 inhibitor for treating and preventing hypopigmentary disorders |
| AU2012203798B2 (en) * | 2005-08-12 | 2013-11-07 | Northrop Grumman Systems Corporation | O-nitro compounds, pharmaceutical compositons thereof and uses thereof |
| US20070135380A1 (en) | 2005-08-12 | 2007-06-14 | Radiorx, Inc. | O-nitro compounds, pharmaceutical compositions thereof and uses thereof |
| WO2012088608A1 (en) | 2010-12-27 | 2012-07-05 | Enobia Canada Limited Partnership | Compositions comprising natriuretic peptides and methods of use thereof |
| US10052366B2 (en) | 2012-05-21 | 2018-08-21 | Alexion Pharmaceuticsl, Inc. | Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof |
| WO2016007873A1 (en) | 2014-07-11 | 2016-01-14 | The Regents Of The University Of Michigan | Compositions and methods for treating craniosynostosis |
| MX389350B (es) | 2014-12-05 | 2025-03-19 | Alexion Pharma Inc | Fosfatasas alcalinas recombinantes y usos de las mismas para el tratamiento de convulsiones. |
| JP6868561B2 (ja) | 2015-01-28 | 2021-05-12 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | アルカリホスファターゼ欠損を有する被験者を治療する方法 |
| CN108350440A (zh) | 2015-08-17 | 2018-07-31 | 阿雷克森制药公司 | 碱性磷酸酯的制造 |
| JP6868617B2 (ja) | 2015-09-28 | 2021-05-12 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | 低ホスファターゼ血症の組織非特異的アルカリホスファターゼ（ｔｎｓａｌｐ）酵素補充療法に有効な投薬計画の特定 |
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| JP7613826B2 (ja) | 2016-04-01 | 2025-01-15 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | アルカリホスファターゼによって筋力低下を治療すること |
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| LV11542B (en) * | 1995-03-30 | 1997-02-20 | Latvijas Organiskas Sintezes Instituts | Substituted 1,3,9,11-tetraoxa-4,5,7,8-tetraazaundecadien-4,7-dioxides-5,7, preparation and use thereof |
| WO1999003462A1 (en) * | 1997-07-14 | 1999-01-28 | Brigham And Women's Hospital | Modification of nitric oxide activity to treat fas-induced pathologies |
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| US20010038832A1 (en) * | 2000-04-11 | 2001-11-08 | Benjamin Bonavida | Nitric oxide and analogues thereof effectuate sensitization of neoplasm and immunologically undesired tissues to cytotoxicity |
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-
2003
- 2003-03-06 JP JP2003572598A patent/JP2005527510A/ja active Pending
- 2003-03-06 EP EP03706181A patent/EP1492567A1/en not_active Withdrawn
- 2003-03-06 WO PCT/CA2003/000313 patent/WO2003074082A1/en not_active Ceased
- 2003-03-06 AU AU2003208228A patent/AU2003208228A1/en not_active Abandoned
- 2003-03-06 CA CA002478145A patent/CA2478145A1/en not_active Abandoned
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| JP2011507968A (ja) * | 2007-12-27 | 2011-03-10 | エイヤーズ ファーマシューティカルズ、インク． | エアロゾル化ニトライトおよび一酸化窒素供与性化合物ならびにそれらの使用 |
| JP2009242378A (ja) * | 2008-03-13 | 2009-10-22 | Chiba Univ | シスプラチン効果増強剤及び抗癌剤キット |
| JP2011521908A (ja) * | 2008-05-09 | 2011-07-28 | デューク ユニバーシティ | チオレドキシンが細胞における一酸化窒素放出を調節するという知見に基づく疾患の治療法 |
| WO2012118042A1 (ja) * | 2011-02-28 | 2012-09-07 | 独立行政法人国立循環器病研究センター | 悪性腫瘍転移抑制用医薬 |
| JP5948683B2 (ja) * | 2011-02-28 | 2016-07-06 | 国立研究開発法人国立循環器病研究センター | 悪性腫瘍転移抑制用医薬 |
| JP2012219050A (ja) * | 2011-04-07 | 2012-11-12 | Nipro Corp | 抗癌剤増感剤 |
| JP2017515800A (ja) * | 2014-04-08 | 2017-06-15 | ザ・メソジスト・ホスピタル | ｉＮＯＳ阻害組成物および乳がん治療薬としてのその使用 |
| US10420838B2 (en) | 2014-04-08 | 2019-09-24 | The Methodist Hospital | Methods for treating cancer using iNOS-inhibitory compositions |
| JP2020128445A (ja) * | 2014-04-08 | 2020-08-27 | ザ・メソジスト・ホスピタル | ｉＮＯＳ阻害組成物および乳がん治療薬としてのその使用 |
| US11357850B2 (en) | 2014-04-08 | 2022-06-14 | The Methodist Hospital | Methods for treating breast cancer using INOS-inhibitory compositions |
| JP2024128025A (ja) * | 2014-04-08 | 2024-09-20 | ザ・メソジスト・ホスピタル | ｉＮＯＳ阻害組成物および乳がん治療薬としてのその使用 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003208228A1 (en) | 2003-09-16 |
| EP1492567A1 (en) | 2005-01-05 |
| CA2478145A1 (en) | 2003-09-12 |
| WO2003074082A1 (en) | 2003-09-12 |
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