JP2005527493A - 光線力学療法のためのシステムおよび方法 - Google Patents

光線力学療法のためのシステムおよび方法 Download PDF

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Publication number
JP2005527493A
JP2005527493A JP2003561639A JP2003561639A JP2005527493A JP 2005527493 A JP2005527493 A JP 2005527493A JP 2003561639 A JP2003561639 A JP 2003561639A JP 2003561639 A JP2003561639 A JP 2003561639A JP 2005527493 A JP2005527493 A JP 2005527493A
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patient
photoreactive agent
retina
eye
photoreactive
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JP2005527493A5 (US20030167033A1-20030904-C00007.png
Inventor
ジェイムズ・チェン
ジュリーン・クリストファーセン
ニック・イェオ
グレッグ・ヒーコック
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Light Sciences Corp
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Light Sciences Corp
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/411—Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/0079—Methods or devices for eye surgery using non-laser electromagnetic radiation, e.g. non-coherent light or microwaves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0061—5-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0076—PDT with expanded (metallo)porphyrins, i.e. having more than 20 ring atoms, e.g. texaphyrins, sapphyrins, hexaphyrins, pentaphyrins, porphocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0601—Apparatus for use inside the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F2009/00861—Methods or devices for eye surgery using laser adapted for treatment at a particular location
    • A61F2009/00863—Retina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F9/009—Auxiliary devices making contact with the eyeball and coupling in laser light, e.g. goniolenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/065—Light sources therefor
    • A61N2005/0651—Diodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/065—Light sources therefor
    • A61N2005/0651—Diodes
    • A61N2005/0652—Arrays of diodes
JP2003561639A 2002-01-23 2003-01-23 光線力学療法のためのシステムおよび方法 Pending JP2005527493A (ja)

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Application Number Priority Date Filing Date Title
US35146002P 2002-01-23 2002-01-23
PCT/US2003/002303 WO2003061696A2 (en) 2002-01-23 2003-01-23 Systems and methods for photodynamic therapy

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JP2005527493A true JP2005527493A (ja) 2005-09-15
JP2005527493A5 JP2005527493A5 (US20030167033A1-20030904-C00007.png) 2006-03-09

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EP (1) EP1467760A2 (US20030167033A1-20030904-C00007.png)
JP (1) JP2005527493A (US20030167033A1-20030904-C00007.png)
CA (1) CA2473924A1 (US20030167033A1-20030904-C00007.png)
WO (1) WO2003061696A2 (US20030167033A1-20030904-C00007.png)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007086395A1 (ja) * 2006-01-24 2007-08-02 Hamamatsu Foundation For Science And Technology Promotion 光線力学的療法用キット
JP2010513363A (ja) * 2006-12-22 2010-04-30 バイオフロンテラ バイオサイエンス ゲゼルシャフト ミット ベシュレンクテル ハフツング ナノエマルジョン
JP2012508189A (ja) * 2008-11-07 2012-04-05 クロクス テクノロジーズ インコーポレイテッド 創傷治癒のための酸化剤および光活性化剤の組み合わせ
JP2012533522A (ja) * 2009-07-17 2012-12-27 クロクス テクノロジーズ インコーポレイテッド 口腔内消毒および口腔疾患の処置のための酸化剤、光増感剤および創傷治癒剤の組み合わせ
KR20140048878A (ko) * 2011-04-29 2014-04-24 오삐또 유니베르시테르 드 제네브 각막 질환의 치료 및/또는 예방을 위한 장치
JP2014185151A (ja) * 2013-03-22 2014-10-02 Wuxi Zhaozhen Radiation Technology Co Ltd 速立酸素による病気を治療するウィルス不活薬物を調製する応用
JP2016531591A (ja) * 2013-09-18 2016-10-13 オーラ バイオサイエンシーズ， インコーポレイテッド 腫瘍を診断および処置するためのウイルス様粒子結合体
JP2017517534A (ja) * 2014-06-09 2017-06-29 クロクス テクノロジーズ インコーポレイテッド シリコンベースの生体光組成物およびその使用
US10300150B2 (en) 2012-02-07 2019-05-28 Aura Biosciences, Inc. Virion-derived nanospheres for selective delivery of therapeutic and diagnostic agents to cancer cells
US10688172B2 (en) 2009-04-13 2020-06-23 INSERM (Institut National de la Santé et de la Recherche Médicale) HPV particles and uses thereof

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000041725A2 (en) * 1999-01-15 2000-07-20 Light Sciences Corporation Therapeutic compositions for metabolic bone disorders or bone metastases
JP2002534218A (ja) 1999-01-15 2002-10-15 ライト サイエンシーズ コーポレイション 非侵襲性の脈管療法
US20030114434A1 (en) * 1999-08-31 2003-06-19 James Chen Extended duration light activated cancer therapy
US7897140B2 (en) 1999-12-23 2011-03-01 Health Research, Inc. Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents
EP1267935A2 (en) * 2000-01-12 2003-01-02 Light Sciences Corporation Novel treatment for eye disease
US7041121B1 (en) * 2002-01-31 2006-05-09 Medtronicvidamed, Inc. Apparatus for treating prostate cancer and method for same
WO2004002476A2 (en) 2002-06-27 2004-01-08 Health Research, Inc. Fluorinated chlorin and bacteriochlorin photosensitizers for photodynamic therapy
US7931028B2 (en) * 2003-08-26 2011-04-26 Jay Harvey H Skin injury or damage prevention method using optical radiation
US7699058B1 (en) 2002-11-08 2010-04-20 Jay Harvey H Hair treatment method
US10376711B2 (en) 2003-03-14 2019-08-13 Light Sciences Oncology Inc. Light generating guide wire for intravascular use
CN2885311Y (zh) 2006-01-18 2007-04-04 郑成福 经尿道光动力疗法前列腺治疗仪
EP1470837A3 (en) * 2003-04-23 2005-08-10 John Tulip Switched photodynamic therapy apparatus and method
US7090670B2 (en) * 2003-12-31 2006-08-15 Reliant Technologies, Inc. Multi-spot laser surgical apparatus and method
US7706863B2 (en) * 2004-01-21 2010-04-27 University Of Washington Methods for assessing a physiological state of a mammalian retina
EP1720609A1 (en) * 2004-02-13 2006-11-15 QLT, Inc. Photodynamic therapy for the treatment of prostatic conditions
US7992570B2 (en) * 2004-04-22 2011-08-09 Light Sciences Oncology, Inc. Fractionated light PDT therapy for posterior eye disease
US7825153B2 (en) * 2004-08-16 2010-11-02 Ceramoptec Industries, Inc. Photosensitizer formulations and their use
TW200610555A (en) * 2004-09-24 2006-04-01 Light Sciences Corp Extended treatment of tumors through vessel occlusion with light activated drugs
WO2006041744A2 (en) * 2004-10-05 2006-04-20 Light Sciences Corporation Low energy pdt for ocular disease
EP1808198A4 (en) * 2004-11-02 2010-04-21 Univ Keio APPARATUS FOR PHOTODYNAMIC THERAPY
US20060122619A1 (en) * 2004-12-03 2006-06-08 Kablik Joseph J Devices and systems for illuminating or irradiating a light-sensitive sealant for polymerization and cross-linking and methods of using the same
JPWO2006075678A1 (ja) * 2005-01-14 2008-06-12 財団法人浜松科学技術研究振興会 光感受性化合物
US20060229689A1 (en) * 2005-04-08 2006-10-12 Led Technologies, Llc LED therapy device
US20070049996A1 (en) * 2005-08-29 2007-03-01 Reliant Technologies, Inc. Monitoring Method and Apparatus for Fractional Photo-Therapy Treatment
JP2009506835A (ja) * 2005-08-29 2009-02-19 リライアント・テクノロジーズ・インコーポレイテッド 熱誘起組織治療を監視し制御する方法および装置
US8480797B2 (en) 2005-09-12 2013-07-09 Abela Pharmaceuticals, Inc. Activated carbon systems for facilitating use of dimethyl sulfoxide (DMSO) by removal of same, related compounds, or associated odors
US9427419B2 (en) 2005-09-12 2016-08-30 Abela Pharmaceuticals, Inc. Compositions comprising dimethyl sulfoxide (DMSO)
WO2007033180A1 (en) 2005-09-12 2007-03-22 Abela Pharmaceuticals, Inc. Materials for facilitating administration of dimethyl sulfoxide (dmso) and related compounds
US7955418B2 (en) 2005-09-12 2011-06-07 Abela Pharmaceuticals, Inc. Systems for removing dimethyl sulfoxide (DMSO) or related compounds or odors associated with same
PL1951184T3 (pl) 2005-11-09 2012-06-29 Valeant Pharmaceuticals Int Inc Kompozycje do wybielania zębów i sposoby
US20080177220A1 (en) * 2006-01-06 2008-07-24 The Curators Of The University Of Missouri Ultrasound-Mediated Transcleral Drug Delivery
JP5033178B2 (ja) * 2006-04-28 2012-09-26 オンディーヌ インターナショナル リミテッド 光殺菌伝達装置および方法
WO2008001242A2 (en) * 2006-06-14 2008-01-03 Koninklijke Philips Electronics N. V. Phototherapy device
EP2029218B1 (en) * 2006-06-15 2019-08-14 PolyPharma Pty Ltd A delivery system
DE102006030219A1 (de) * 2006-06-30 2008-01-03 Iroc Ag Bestrahlungssystem für medizinische Anwendungen
US20100266989A1 (en) 2006-11-09 2010-10-21 Klox Technologies Inc. Teeth whitening compositions and methods
US8435234B2 (en) * 2007-02-06 2013-05-07 Reliant Technologies, Inc. Method and apparatus for monitoring and controlling laser-induced tissue treatment
US8622991B2 (en) 2007-03-19 2014-01-07 Insuline Medical Ltd. Method and device for drug delivery
US9220837B2 (en) 2007-03-19 2015-12-29 Insuline Medical Ltd. Method and device for drug delivery
CN104069567A (zh) 2007-03-19 2014-10-01 茵苏莱恩医药有限公司 药物输送设备
US20090117053A1 (en) * 2007-11-06 2009-05-07 Boston Scientific Scimed, Inc. Local delivery of 5-aminolevulinic-acid based compounds to tissues and organs for diagnostic and therapeutic purposes
US8409133B2 (en) 2007-12-18 2013-04-02 Insuline Medical Ltd. Drug delivery device with sensor for closed-loop operation
CN101970049A (zh) * 2008-02-13 2011-02-09 安德里亚斯·罗斯 提供径向光输出模式的光递送装置
US9358369B1 (en) * 2008-08-13 2016-06-07 Abbott Cardiovascular Systems Inc. Reduced profile and enhanced flexibility delivery catheters for light activated agents
BRPI0921494A2 (pt) 2008-11-03 2018-10-30 Prad Reasearch And Development Ltd método de planejamento de uma operação de amostragem para uma formação subterrãnea, método de contolar uma operação de amostragem de formação subterrânea, método de controlar uma operação de perfuração para uma formação subterrãnea, e método de realizar uma amostragem durante a operação de perfuração.
MX2011004817A (es) 2008-11-07 2011-07-28 Insuline Medical Ltd Dispositivo y metodo para suministrar farmacos.
US8771741B2 (en) * 2009-01-23 2014-07-08 The Penn State Research Foundation In vivo photodynamic therapy of cancer via a near infrared agent encapsulated in calcium phosphate nanoparticles
JP5947721B2 (ja) 2009-10-30 2016-07-06 アベラ ファーマスーティカルズ インコーポレイテッド 変形性関節症を治療するためのジメチルスルホキシド（ｄｍｓｏ）およびメチルスルホニルメタン（ｍｓｍ）製剤
US20110206737A1 (en) * 2010-02-24 2011-08-25 Empire Technology Development Llc Photosensitizer-containing composition
JP5719159B2 (ja) * 2010-03-15 2015-05-13 ソニー株式会社 評価装置
EP3556330A1 (en) 2010-03-19 2019-10-23 Avedro, Inc. Systems for applying and monitoring eye therapy
JP6122845B2 (ja) 2011-06-02 2017-04-26 アヴェドロ・インコーポレーテッドＡｖｅｄｒｏ，Ｉｎｃ． 時間ベースの光活性剤の送達又は光活性マーカの存在をモニターするシステム及び方法
EP2728344A4 (en) * 2011-06-29 2015-04-08 Kyoto Prefectural Public Univ Corp DEVICE AND METHOD FOR IDENTIFYING THE SITE OF A TUMOR
US20130281913A1 (en) 2012-04-20 2013-10-24 Klox Technologies Inc. Biophotonic compositions and methods for providing biophotonic treatment
US11116841B2 (en) 2012-04-20 2021-09-14 Klox Technologies Inc. Biophotonic compositions, kits and methods
JP6231570B2 (ja) 2012-09-14 2017-11-15 ヴァレアント ファーマシューティカルズ インターナショナル インコーポレイテッドＶａｌｅａｎｔ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｔｅｒｎａｔｉｏｎａｌ， Ｉｎｃ． 歯のホワイトニングのための組成物および方法
US20140276354A1 (en) 2013-03-14 2014-09-18 Klox Technologies Inc. Biophotonic materials and uses thereof
CA2916337C (en) 2013-07-03 2022-03-22 Klox Technologies Inc. Biophotonic compositions comprising a chromophore and a gelling agent for treating wounds
US20160367672A1 (en) * 2014-03-03 2016-12-22 University Of Southern California Methods and systems for treating tumors
AR099941A1 (es) 2014-04-01 2016-08-31 Klox Tech Inc Composiciones para relleno de tejido y métodos de uso
WO2016054079A1 (en) 2014-09-29 2016-04-07 Zyomed Corp. Systems and methods for blood glucose and other analyte detection and measurement using collision computing
EP3212140B1 (en) 2014-10-27 2021-12-01 Avedro, Inc. Systems for cross-linking treatments of an eye
EP3212826B1 (en) 2014-10-31 2020-10-14 Klox Technologies Inc. Photoactivatable fibers and fabric media
US10114205B2 (en) 2014-11-13 2018-10-30 Avedro, Inc. Multipass virtually imaged phased array etalon
CN106999722B (zh) * 2014-11-19 2019-03-22 夏普株式会社 光动力学治疗装置
EP3285704B1 (en) 2015-04-24 2020-11-18 Avedro Inc. Systems for photoactivating a photosensitizer applied to an eye
WO2016191342A1 (en) 2015-05-22 2016-12-01 Avedro, Inc. Systems and methods for monitoring cross-linking activity for corneal treatments
EP3324973B1 (en) 2015-07-21 2020-06-03 Avedro, Inc. Treament of an eye with a photosensitizer
CN106620893B (zh) * 2015-07-23 2021-07-30 爱博诺德(北京)医疗科技股份有限公司 用于眼部疾病光治疗的材料
US9554738B1 (en) 2016-03-30 2017-01-31 Zyomed Corp. Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing
FI3245988T3 (fi) * 2016-05-18 2024-02-22 Sonikure Holdings Ltd Järjestelmä lääkkeiden antamiseksi ultraäänivahvisteisesti kovakalvon läpi
US11850188B2 (en) 2019-04-01 2023-12-26 Amo Development, Llc Corneal lenticule extraction tool
US11529153B2 (en) 2020-08-21 2022-12-20 University Of Washington Vaccine generation
WO2022040258A1 (en) 2020-08-21 2022-02-24 University Of Washington Disinfection method and apparatus
US11425905B2 (en) 2020-09-02 2022-08-30 University Of Washington Antimicrobial preventive netting
US11458220B2 (en) 2020-11-12 2022-10-04 Singletto Inc. Microbial disinfection for personal protection equipment
CN112451862B (zh) * 2020-11-24 2023-03-28 深圳罗兹曼国际转化医学研究院 光动力治疗系统及其控制方法

Family Cites Families (96)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US127224A (en) * 1872-05-28 Improvement in cotton-seed cleaners
US46983A (en) * 1865-03-28 Improvement in treating ores
US115694A (en) * 1871-06-06 William e
US41768A (en) * 1864-03-01 Improvement in wrenches
US217690A (en) * 1879-07-22 Improvement in mechanical telephones
US41725A (en) * 1864-02-23 Improvement in button-hole cutters
US10500A (en) * 1854-02-07 Tool-holder
US41726A (en) * 1864-02-23 Improved mode of raising sunken vessels
US178458A (en) * 1876-06-06 Improvement in pessaries
US41727A (en) * 1864-02-23 Improvement in fibrous batting or wadding
US114434A (en) * 1871-05-02 Improvement in dry-earth closets
US178216A (en) * 1876-05-30 Improvement in electro-magnetic annunciators
US151087A (en) * 1874-05-19 Improvement in stench-traps
US127230A (en) * 1872-05-28 Improvement in lamp-chimney cleaners
US87205A (en) * 1869-02-23 Improved velocipede
US4521762A (en) * 1981-08-27 1985-06-04 Gte Automatic Electric Laboratories, Incorporated Integratable D/A converter
US4649151A (en) * 1982-09-27 1987-03-10 Health Research, Inc. Drugs comprising porphyrins
US4577636A (en) * 1982-11-23 1986-03-25 The Beth Israel Hospital Association Method for diagnosis of atherosclerosis
US4675338A (en) * 1984-07-18 1987-06-23 Nippon Petrochemicals Co., Ltd. Tetrapyrrole therapeutic agents
US4753958A (en) * 1985-02-07 1988-06-28 University Of Cal Photochemotherapy of epithelial diseases with derivatives of hematoporphyrins
US5216012A (en) * 1986-01-02 1993-06-01 University Of Toledo Production and use of purpurins, chlorins and purpurin- and chlorin-containing compositions
US5494793A (en) * 1986-12-15 1996-02-27 British Technology Group Usa Inc. Monomeric phthalocyanine reagents
US5283255A (en) * 1987-01-20 1994-02-01 The University Of British Columbia Wavelength-specific cytotoxic agents
US5095030A (en) * 1987-01-20 1992-03-10 University Of British Columbia Wavelength-specific cytotoxic agents
US5004811A (en) * 1987-12-24 1991-04-02 Nippon Petrochemicals Company, Ltd. Tetrapyrrole aminocarboxylic acids
US4823244A (en) * 1988-01-29 1989-04-18 Niagara Medical Innovations Inc. Light source assembly
US5026367A (en) * 1988-03-18 1991-06-25 Cardiovascular Laser Systems, Inc. Laser angioplasty catheter and a method for use thereof
US4925736A (en) * 1988-07-06 1990-05-15 Long Island Jewish Medical Center Topical hematoporphyrin
US5002962A (en) * 1988-07-20 1991-03-26 Health Research, Inc. Photosensitizing agents
US4998930A (en) * 1988-08-03 1991-03-12 Phototherapeutic Systems Intracavity laser phototherapy method
US4935498A (en) * 1989-03-06 1990-06-19 Board Of Regents, The University Of Texas System Expanded porphyrins: large porphyrin-like tripyrroledimethine-derived macrocycles
US4997639A (en) * 1989-11-27 1991-03-05 Nippon Petrochemicals Company, Limited Method for detecting cholesterol deposited in bodies of mammals
US5594136A (en) * 1989-12-21 1997-01-14 Pharmacyclics, Inc. Texaphyrin solid supports and devices
EP0510007B1 (en) * 1990-01-08 1996-05-08 Health Research, Inc. A submersible lens fiberoptic assembly
US5484778C1 (en) * 1990-07-17 2001-05-08 Univ Cleveland Hospitals Phthalocynine photosensitizers for photodynamic therapy and methods for their use
US5500009A (en) * 1990-11-15 1996-03-19 Amron, Ltd. Method of treating herpes
JP3154742B2 (ja) * 1991-04-30 2001-04-09 日本石油化学株式会社 哺乳類の動脈硬化症治療剤
US5769844A (en) * 1991-06-26 1998-06-23 Ghaffari; Shahriar Conventional light-pumped high power system for medical applications
US5330741A (en) * 1992-02-24 1994-07-19 The Regents Of The University Of California Long-wavelength water soluble chlorin photosensitizers useful for photodynamic therapy and diagnosis of tumors
US5965132A (en) * 1992-03-05 1999-10-12 Board Of Regents, The University Of Texas System Methods and compositions for targeting the vasculature of solid tumors
ATE239506T1 (de) * 1992-03-05 2003-05-15 Univ Texas Verwendung von immunokonjugate zur diagnose und/oder therapie der vaskularisierten tumoren
EP0646019B9 (en) * 1992-06-09 2002-12-18 Neorx Corporation Biotin-DOTA conjugates and their use in pretargeting methods
US6217869B1 (en) * 1992-06-09 2001-04-17 Neorx Corporation Pretargeting methods and compounds
US5298018A (en) * 1992-08-14 1994-03-29 Pdt Cardiovascular, Inc. Method for treating cardiovascular disease through adjunctive photodynamic therapy
DK0660712T3 (da) * 1992-09-21 2001-08-27 Quadra Logic Tech Inc Transcutation in vivo-aktivering af lysfølsomme midler i blod
EP0680365B1 (en) * 1992-11-20 2000-03-01 The University Of British Columbia Activation of photosensitive agents
US5482698A (en) * 1993-04-22 1996-01-09 Immunomedics, Inc. Detection and therapy of lesions with biotin/avidin polymer conjugates
US5420768A (en) * 1993-09-13 1995-05-30 Kennedy; John Portable led photocuring device
US5514669A (en) * 1993-09-29 1996-05-07 Medical College Of Ohio Use of photodynamic therapy to treat prostatic tissue
US5913834A (en) * 1993-11-04 1999-06-22 Francais; Caramia System for imparting sensory effects across a mother's abdomen to a fetus and monitoring effects on the fetus
US6015897A (en) * 1993-12-07 2000-01-18 Neorx Corporation Biotinamido-n-methylglycyl-seryl-o-succinamido-benzyl dota
IL108918A (en) * 1994-03-10 1997-04-15 Medic Lightech Ltd Apparatus for efficient photodynamic treatment
US5616140A (en) * 1994-03-21 1997-04-01 Prescott; Marvin Method and apparatus for therapeutic laser treatment
US5498710A (en) * 1994-04-22 1996-03-12 Health Research, Inc. Alkyl ether analogues of benzoporphyrin derivatives
US5591847A (en) * 1994-05-23 1997-01-07 Health Research, Inc. Long wavelength absorbing photosensitizers related to purpurin-18, bacteriopurpurin-18 and related compounds with imide linkages
US5519534A (en) * 1994-05-25 1996-05-21 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Irradiance attachment for an optical fiber to provide a uniform level of illumination across a plane
US5591855A (en) * 1994-10-14 1997-01-07 Cephalon, Inc. Fused pyrrolocarbazoles
US5746494A (en) * 1994-11-22 1998-05-05 Asahi Kogaku Kogyo Kabushiki Kaisha Illuminating apparatus of endoscope
US5882328A (en) * 1995-01-13 1999-03-16 Qlt Phototherapeutics, Inc. Method to prevent transplant rejection
US5735817A (en) * 1995-05-19 1998-04-07 Shantha; T. R. Apparatus for transsphenoidal stimulation of the pituitary gland and adjoining brain structures
US5571152A (en) * 1995-05-26 1996-11-05 Light Sciences Limited Partnership Microminiature illuminator for administering photodynamic therapy
JPH0947518A (ja) * 1995-06-26 1997-02-18 Lederle Japan Ltd フォトダイナミックセラピ用光ファイバレーザ導光プローブ
IT1275571B (it) * 1995-07-19 1997-08-07 Consiglio Nazionale Ricerche Substrati fluorogenici suscettibili di fotoattivazione previa trasformazione per via enzimatica atti alla diagnosi ed alla terapia fotodinamica dei tumori
US5912257A (en) * 1995-09-06 1999-06-15 The Research Foundation Of State University Of New York Two-photon upconverting dyes and applications
JP2961074B2 (ja) * 1995-09-06 1999-10-12 明治製菓株式会社 光化学療法用の新生血管閉塞剤
US5885557A (en) * 1996-02-08 1999-03-23 Estee Lauder Inc. Compositions useful in the phototherapeutic treatment of proliferative skin disorders
US5800478A (en) * 1996-03-07 1998-09-01 Light Sciences Limited Partnership Flexible microcircuits for internal light therapy
US5770730A (en) * 1996-03-08 1998-06-23 Health Research, Inc. Synthesis of carbodimide analogs of chlorins and bacteriochlorins and their use for diagnosis and treatment of cancer
US5756541A (en) * 1996-03-11 1998-05-26 Qlt Phototherapeutics Inc Vision through photodynamic therapy of the eye
US6013053A (en) * 1996-05-17 2000-01-11 Qlt Photo Therapeutics Inc. Balloon catheter for photodynamic therapy
US5709653A (en) * 1996-07-25 1998-01-20 Cordis Corporation Photodynamic therapy balloon catheter with microporous membrane
US5904147A (en) * 1996-08-16 1999-05-18 University Of Massachusetts Intravascular catheter and method of controlling hemorrhage during minimally invasive surgery
US5715837A (en) * 1996-08-29 1998-02-10 Light Sciences Limited Partnership Transcutaneous electromagnetic energy transfer
US5849027A (en) * 1996-09-04 1998-12-15 Mbg Technologies, Inc. Photodynamic therapy method and apparatus
US5913884A (en) * 1996-09-19 1999-06-22 The General Hospital Corporation Inhibition of fibrosis by photodynamic therapy
EP0945454B1 (en) * 1996-10-01 2003-07-02 Wyeth Lederle Japan LTD. Iminochlorinaspartic acid derivatives
US5741316A (en) * 1996-12-02 1998-04-21 Light Sciences Limited Partnership Electromagnetic coil configurations for power transmission through tissue
US6080160A (en) * 1996-12-04 2000-06-27 Light Sciences Limited Partnership Use of shape memory alloy for internally fixing light emitting device at treatment site
US6021347A (en) * 1996-12-05 2000-02-01 Herbst; Ewa Electrochemical treatment of malignant tumors
US5766222A (en) * 1997-07-07 1998-06-16 Petit; Michael G. Nipple illuminator for photodynamic therapy
US6058937A (en) * 1997-07-18 2000-05-09 Miravant Systems, Inc. Photodynamic Therapy of highly vascularized tissue
US6183444B1 (en) * 1998-05-16 2001-02-06 Microheart, Inc. Drug delivery module
US5865840A (en) * 1997-10-22 1999-02-02 Light Sciences Limited Partnership Enhancement of light activation effect by immune augmentation
US6071944A (en) * 1997-11-12 2000-06-06 Bowling Green State University Method of treatment of pigmented cancer cells utilizing photodynamic therapy
US20030030342A1 (en) * 1998-02-10 2003-02-13 Chen James C. Contactless energy transfer apparatus
US6344050B1 (en) * 1998-12-21 2002-02-05 Light Sciences Corporation Use of pegylated photosensitizer conjugated with an antibody for treating abnormal tissue
US6602274B1 (en) * 1999-01-15 2003-08-05 Light Sciences Corporation Targeted transcutaneous cancer therapy
US6210425B1 (en) * 1999-07-08 2001-04-03 Light Sciences Corporation Combined imaging and PDT delivery system
US6238426B1 (en) * 1999-07-19 2001-05-29 Light Sciences Corporation Real-time monitoring of photodynamic therapy over an extended time
US20030114434A1 (en) * 1999-08-31 2003-06-19 James Chen Extended duration light activated cancer therapy
US6534040B2 (en) * 1999-12-23 2003-03-18 Health Research, Inc. Chlorin and bacteriochlorin-based aminophenyl DTPA and N2S2 conjugates for MR contrast media and radiopharmaceuticals
US6520669B1 (en) * 2000-06-19 2003-02-18 Light Sciences Corporation Flexible substrate mounted solid-state light sources for exterior vehicular lighting
US6559374B2 (en) * 2000-07-21 2003-05-06 North Carolina State University Trans beta substituted chlorins and methods of making and using the same
US6580228B1 (en) * 2000-08-22 2003-06-17 Light Sciences Corporation Flexible substrate mounted solid-state light sources for use in line current lamp sockets
WO2004002476A2 (en) * 2002-06-27 2004-01-08 Health Research, Inc. Fluorinated chlorin and bacteriochlorin photosensitizers for photodynamic therapy
US7053210B2 (en) * 2002-07-02 2006-05-30 Health Research, Inc. Efficient synthesis of pyropheophorbide a and its derivatives

Cited By (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007086395A1 (ja) * 2006-01-24 2007-08-02 Hamamatsu Foundation For Science And Technology Promotion 光線力学的療法用キット
JPWO2007086395A1 (ja) * 2006-01-24 2009-06-18 財団法人浜松科学技術研究振興会 光線力学的療法用キット
JP2010513363A (ja) * 2006-12-22 2010-04-30 バイオフロンテラ バイオサイエンス ゲゼルシャフト ミット ベシュレンクテル ハフツング ナノエマルジョン
JP2016193950A (ja) * 2008-11-07 2016-11-17 クロクス テクノロジーズ インコーポレイテッド ヒアルロン酸、グルコサミン、およびアラントインを含む、酸化的光活性化皮膚再生組成物
JP2012508190A (ja) * 2008-11-07 2012-04-05 クロクス テクノロジーズ インコーポレイテッド ヒアルロン酸、グルコサミン、およびアラントインを含む、酸化的光活性化皮膚再生組成物
JP2016193951A (ja) * 2008-11-07 2016-11-17 クロクス テクノロジーズ インコーポレイテッド 創傷治癒のための酸化剤および光活性化剤の組み合わせ
JP2013253109A (ja) * 2008-11-07 2013-12-19 Klox Technologies Inc 創傷治癒のための酸化剤および光活性化剤の組み合わせ
JP2013253110A (ja) * 2008-11-07 2013-12-19 Klox Technologies Inc ヒアルロン酸、グルコサミン、およびアラントインを含む、酸化的光活性化皮膚再生組成物
JP2012508189A (ja) * 2008-11-07 2012-04-05 クロクス テクノロジーズ インコーポレイテッド 創傷治癒のための酸化剤および光活性化剤の組み合わせ
JP2016020386A (ja) * 2008-11-07 2016-02-04 クロクス テクノロジーズ インコーポレイテッド ヒアルロン酸、グルコサミン、およびアラントインを含む、酸化的光活性化皮膚再生組成物
JP2016006120A (ja) * 2008-11-07 2016-01-14 クロクス テクノロジーズ インコーポレイテッド 創傷治癒のための酸化剤および光活性化剤の組み合わせ
US10688172B2 (en) 2009-04-13 2020-06-23 INSERM (Institut National de la Santé et de la Recherche Médicale) HPV particles and uses thereof
JP2012533522A (ja) * 2009-07-17 2012-12-27 クロクス テクノロジーズ インコーポレイテッド 口腔内消毒および口腔疾患の処置のための酸化剤、光増感剤および創傷治癒剤の組み合わせ
JP2014518660A (ja) * 2011-04-29 2014-08-07 ホピトー ユニヴァーシテアーズ ド ジュネーヴ 角膜疾患を治療および／または予防するための装置
KR20140048878A (ko) * 2011-04-29 2014-04-24 오삐또 유니베르시테르 드 제네브 각막 질환의 치료 및/또는 예방을 위한 장치
US10182941B2 (en) 2011-04-29 2019-01-22 Farhad Hafezi Apparatus for the treatment and/or prevention of corneal diseases
KR101995083B1 (ko) * 2011-04-29 2019-07-02 파하드 하페치 각막 질환의 치료 및/또는 예방을 위한 장치
US10300150B2 (en) 2012-02-07 2019-05-28 Aura Biosciences, Inc. Virion-derived nanospheres for selective delivery of therapeutic and diagnostic agents to cancer cells
US10596275B2 (en) 2012-02-07 2020-03-24 Aura Biosciences, Inc. Virion-derived nanospheres for selective delivery of therapeutic and diagnostic agents to cancer cells
JP2014185151A (ja) * 2013-03-22 2014-10-02 Wuxi Zhaozhen Radiation Technology Co Ltd 速立酸素による病気を治療するウィルス不活薬物を調製する応用
JP2019013249A (ja) * 2013-09-18 2019-01-31 オーラ バイオサイエンシーズ， インコーポレイテッド 腫瘍を診断および処置するためのウイルス様粒子結合体
US10588984B2 (en) 2013-09-18 2020-03-17 Aura Biosciences, Inc. Virus-like particle conjugates for diagnosis and treatment of tumors
JP2016531591A (ja) * 2013-09-18 2016-10-13 オーラ バイオサイエンシーズ， インコーポレイテッド 腫瘍を診断および処置するためのウイルス様粒子結合体
US11110181B2 (en) 2013-09-18 2021-09-07 Aura Biosciences, Inc. Virus-like particle conjugates for diagnosis and treatment of tumors
US11806406B2 (en) 2013-09-18 2023-11-07 Aura Biosciences, Inc. Virus-like particle conjugates for diagnosis and treatment of tumors
JP2017517534A (ja) * 2014-06-09 2017-06-29 クロクス テクノロジーズ インコーポレイテッド シリコンベースの生体光組成物およびその使用
JP7017311B2 (ja) 2014-06-09 2022-02-08 広東科洛克生物医薬集団有限公司 シリコンベースの生体光組成物およびその使用
US11266685B2 (en) 2014-06-09 2022-03-08 Klox Technologies Inc. Silicone-based biophotonic compositions and uses thereof

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