|
US4179337A
(en)
|
1973-07-20 |
1979-12-18 |
Davis Frank F |
Non-immunogenic polypeptides
|
|
US4179937A
(en)
*
|
1978-06-02 |
1979-12-25 |
Ocean Ecology Ltd. |
Sound measuring device
|
|
JPS6023084B2
(ja)
|
1979-07-11 |
1985-06-05 |
味の素株式会社 |
代用血液
|
|
US4469863A
(en)
|
1980-11-12 |
1984-09-04 |
Ts O Paul O P |
Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof
|
|
US4640835A
(en)
|
1981-10-30 |
1987-02-03 |
Nippon Chemiphar Company, Ltd. |
Plasminogen activator derivatives
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US4496689A
(en)
|
1983-12-27 |
1985-01-29 |
Miles Laboratories, Inc. |
Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
|
|
US5430136A
(en)
|
1984-10-16 |
1995-07-04 |
Chiron Corporation |
Oligonucleotides having selectably cleavable and/or abasic sites
|
|
US5235033A
(en)
|
1985-03-15 |
1993-08-10 |
Anti-Gene Development Group |
Alpha-morpholino ribonucleoside derivatives and polymers thereof
|
|
US5034506A
(en)
|
1985-03-15 |
1991-07-23 |
Anti-Gene Development Group |
Uncharged morpholino-based polymers having achiral intersubunit linkages
|
|
EP0206448B1
(en)
|
1985-06-19 |
1990-11-14 |
Ajinomoto Co., Inc. |
Hemoglobin combined with a poly(alkylene oxide)
|
|
EP0272253A4
(en)
|
1986-03-07 |
1990-02-05 |
Massachusetts Inst Technology |
METHOD FOR IMPROVING GLYCOPROTE INSTABILITY.
|
|
US4791192A
(en)
|
1986-06-26 |
1988-12-13 |
Takeda Chemical Industries, Ltd. |
Chemically modified protein with polyethyleneglycol
|
|
US5124246A
(en)
|
1987-10-15 |
1992-06-23 |
Chiron Corporation |
Nucleic acid multimers and amplified nucleic acid hybridization assays using same
|
|
US5359100A
(en)
|
1987-10-15 |
1994-10-25 |
Chiron Corporation |
Bifunctional blocked phosphoramidites useful in making nucleic acid mutimers
|
|
US5700637A
(en)
|
1988-05-03 |
1997-12-23 |
Isis Innovation Limited |
Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
|
|
US5216141A
(en)
|
1988-06-06 |
1993-06-01 |
Benner Steven A |
Oligonucleotide analogs containing sulfur linkages
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
US4992378A
(en)
|
1988-12-16 |
1991-02-12 |
The Royal Institution For The Advancement Of Learning (Mcgill University) |
C-DNA encoding human prolactin receptor
|
|
CA2049028A1
(en)
|
1989-03-07 |
1990-09-08 |
Genentech, Inc. |
Covalent conjugates of lipid and oligonucleotide
|
|
US5143854A
(en)
|
1989-06-07 |
1992-09-01 |
Affymax Technologies N.V. |
Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
|
|
WO1991004753A1
(en)
|
1989-10-02 |
1991-04-18 |
Cetus Corporation |
Conjugates of antisense oligonucleotides and therapeutic uses thereof
|
|
US5014802A
(en)
*
|
1990-06-04 |
1991-05-14 |
General Motors Corporation |
Rear steer controller
|
|
US5386023A
(en)
|
1990-07-27 |
1995-01-31 |
Isis Pharmaceuticals |
Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling
|
|
US5602240A
(en)
|
1990-07-27 |
1997-02-11 |
Ciba Geigy Ag. |
Backbone modified oligonucleotide analogs
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
KR100272077B1
(ko)
|
1990-08-29 |
2000-11-15 |
젠팜인터내셔날,인코포레이티드 |
이종 항체를 생산할 수 있는 전이유전자를 가진 인간이외의 동물
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5644048A
(en)
|
1992-01-10 |
1997-07-01 |
Isis Pharmaceuticals, Inc. |
Process for preparing phosphorothioate oligonucleotides
|
|
WO1993022443A1
(en)
|
1992-04-24 |
1993-11-11 |
Sri International |
In vivo homologous sequence targeting in eukaryotic cells
|
|
US5681697A
(en)
|
1993-12-08 |
1997-10-28 |
Chiron Corporation |
Solution phase nucleic acid sandwich assays having reduced background noise and kits therefor
|
|
US5637684A
(en)
|
1994-02-23 |
1997-06-10 |
Isis Pharmaceuticals, Inc. |
Phosphoramidate and phosphorothioamidate oligomeric compounds
|
|
US6015880A
(en)
|
1994-03-16 |
2000-01-18 |
California Institute Of Technology |
Method and substrate for performing multiple sequential reactions on a matrix
|
|
US5807522A
(en)
|
1994-06-17 |
1998-09-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods for fabricating microarrays of biological samples
|
|
US5597909A
(en)
|
1994-08-25 |
1997-01-28 |
Chiron Corporation |
Polynucleotide reagents containing modified deoxyribose moieties, and associated methods of synthesis and use
|
|
US5580731A
(en)
|
1994-08-25 |
1996-12-03 |
Chiron Corporation |
N-4 modified pyrimidine deoxynucleotides and oligonucleotide probes synthesized therewith
|
|
US5681702A
(en)
|
1994-08-30 |
1997-10-28 |
Chiron Corporation |
Reduction of nonspecific hybridization by using novel base-pairing schemes
|
|
US5759776A
(en)
|
1995-06-05 |
1998-06-02 |
California Pacific Medical Center |
Targets for breast cancer diagnosis and treatment
|
|
EP1295952A3
(en)
|
1996-01-23 |
2003-07-09 |
The Board of Trustees of The Leland Stanford Junior University |
Methods for screening for transdominant effector peptides and RNA molecules
|
|
US5776683A
(en)
|
1996-07-11 |
1998-07-07 |
California Pacific Medical Center |
Methods for identifying genes amplified in cancer cells
|
|
US5928870A
(en)
|
1997-06-16 |
1999-07-27 |
Exact Laboratories, Inc. |
Methods for the detection of loss of heterozygosity
|
|
US6074825A
(en)
|
1997-07-31 |
2000-06-13 |
Maine Medical Center |
Stable encapsulated reference nucleic acid and method of making
|
|
US6153441A
(en)
|
1998-02-17 |
2000-11-28 |
Smithkline Beecham Corporation |
Methods of screening for agonists and antagonists for human CCR7 receptor and CKβ-9 ligand and interaction thereof
|
|
EP1358349A2
(en)
|
2000-06-05 |
2003-11-05 |
Avalon Pharmaceuticals |
Cancer gene determination and therapeutic screening using signature gene sets
|
|
US6812339B1
(en)
*
|
2000-09-08 |
2004-11-02 |
Applera Corporation |
Polymorphisms in known genes associated with human disease, methods of detection and uses thereof
|
|
EP1353947A2
(en)
|
2000-12-08 |
2003-10-22 |
Ipsogen |
Gene expression profiling of primary breast carcinomas using arrays of candidate genes
|
|
US20030194702A1
(en)
*
|
2000-12-22 |
2003-10-16 |
Engelhard Eric K. |
Novel compositions and methods for cancer
|
|
US20040072264A1
(en)
*
|
2000-12-22 |
2004-04-15 |
Morris David W. |
Novel compositions and methods for cancer
|
|
MXPA03006617A
(es)
|
2001-01-24 |
2004-12-02 |
Protein Design Labs Inc |
Metodos de diagnostico de cancer de pecho, composiciones y metodos de rastreo de moduladores de cancer de pecho.
|
|
WO2003008583A2
(en)
|
2001-03-02 |
2003-01-30 |
Sagres Discovery |
Novel compositions and methods for cancer
|
|
US20030099974A1
(en)
*
|
2001-07-18 |
2003-05-29 |
Millennium Pharmaceuticals, Inc. |
Novel genes, compositions, kits and methods for identification, assessment, prevention, and therapy of breast cancer
|
|
NL1033850C2
(nl)
|
2007-05-15 |
2008-11-18 |
3Force B V |
Brandersysteem met voorgemengde branders en vlam-overdrachtsmiddelen.
|
|
WO2013037693A2
(de)
|
2011-09-15 |
2013-03-21 |
Convergent Information Technologies Gmbh |
System und verfahren zur automatisierten erstellung von roboterprogrammen
|
|
US9505153B2
(en)
|
2012-02-13 |
2016-11-29 |
Radius Engineering, Inc. |
Reusable cartridge for injection molding
|