JP2005520536A5 - - Google Patents
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- Publication number
- JP2005520536A5 JP2005520536A5 JP2003577810A JP2003577810A JP2005520536A5 JP 2005520536 A5 JP2005520536 A5 JP 2005520536A5 JP 2003577810 A JP2003577810 A JP 2003577810A JP 2003577810 A JP2003577810 A JP 2003577810A JP 2005520536 A5 JP2005520536 A5 JP 2005520536A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- cap
- group
- sequence selected
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000007523 nucleic acids Chemical class 0.000 claims 23
- 238000000034 method Methods 0.000 claims 18
- 108090000623 proteins and genes Proteins 0.000 claims 17
- 108020004707 nucleic acids Proteins 0.000 claims 12
- 102000039446 nucleic acids Human genes 0.000 claims 12
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 11
- 230000000694 effects Effects 0.000 claims 8
- 102000004169 proteins and genes Human genes 0.000 claims 8
- 201000009030 Carcinoma Diseases 0.000 claims 5
- 206010028980 Neoplasm Diseases 0.000 claims 5
- 230000000975 bioactive effect Effects 0.000 claims 4
- 229940000406 drug candidate Drugs 0.000 claims 4
- 201000011510 cancer Diseases 0.000 claims 3
- 239000000523 sample Substances 0.000 claims 3
- 238000012216 screening Methods 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 239000013604 expression vector Substances 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 239000003112 inhibitor Substances 0.000 claims 2
- 229920001184 polypeptide Polymers 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 108020004414 DNA Proteins 0.000 claims 1
- 238000000018 DNA microarray Methods 0.000 claims 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 claims 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 238000009396 hybridization Methods 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 238000006386 neutralization reaction Methods 0.000 claims 1
- 230000003472 neutralizing effect Effects 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 238000012163 sequencing technique Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/105,612 US20030165878A1 (en) | 2000-12-22 | 2002-03-20 | Novel compositions and methods in cancer associated with altered expression of MCM3AP |
| PCT/US2003/008071 WO2003079977A2 (en) | 2002-03-20 | 2003-03-17 | Novel compositions and methods in cancer associated with altered expression of mcm3ap |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009107191A Division JP2009195244A (ja) | 2002-03-20 | 2009-04-24 | Mcm3apの変更された発現に関連する癌における新規組成物および方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005520536A JP2005520536A (ja) | 2005-07-14 |
| JP2005520536A5 true JP2005520536A5 (enExample) | 2006-05-11 |
Family
ID=28452442
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003577810A Pending JP2005520536A (ja) | 2002-03-20 | 2003-03-17 | Mcm3apの変更された発現に関連する癌における新規組成物および方法 |
| JP2009107191A Pending JP2009195244A (ja) | 2002-03-20 | 2009-04-24 | Mcm3apの変更された発現に関連する癌における新規組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009107191A Pending JP2009195244A (ja) | 2002-03-20 | 2009-04-24 | Mcm3apの変更された発現に関連する癌における新規組成物および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20030165878A1 (enExample) |
| EP (1) | EP1490690A4 (enExample) |
| JP (2) | JP2005520536A (enExample) |
| AU (1) | AU2003225826B2 (enExample) |
| CA (1) | CA2479719A1 (enExample) |
| WO (1) | WO2003079977A2 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070207120A1 (en) * | 2004-04-14 | 2007-09-06 | Sarah Drayton | Selective Killing Of Cancer Cells By Induction Of Acetyltransferase Via Tnf-Alpha And Il-6 |
| JP5435529B2 (ja) | 2005-09-02 | 2014-03-05 | 東レ株式会社 | 腎ガン診断、腎ガン患者予後予測のための組成物および方法 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) * | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| JPS6023084B2 (ja) * | 1979-07-11 | 1985-06-05 | 味の素株式会社 | 代用血液 |
| US4469863A (en) * | 1980-11-12 | 1984-09-04 | Ts O Paul O P | Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof |
| US4640835A (en) * | 1981-10-30 | 1987-02-03 | Nippon Chemiphar Company, Ltd. | Plasminogen activator derivatives |
| US4816567A (en) * | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4496689A (en) * | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
| US5430136A (en) * | 1984-10-16 | 1995-07-04 | Chiron Corporation | Oligonucleotides having selectably cleavable and/or abasic sites |
| US5235033A (en) * | 1985-03-15 | 1993-08-10 | Anti-Gene Development Group | Alpha-morpholino ribonucleoside derivatives and polymers thereof |
| US5034506A (en) * | 1985-03-15 | 1991-07-23 | Anti-Gene Development Group | Uncharged morpholino-based polymers having achiral intersubunit linkages |
| EP0206448B1 (en) * | 1985-06-19 | 1990-11-14 | Ajinomoto Co., Inc. | Hemoglobin combined with a poly(alkylene oxide) |
| US4791192A (en) * | 1986-06-26 | 1988-12-13 | Takeda Chemical Industries, Ltd. | Chemically modified protein with polyethyleneglycol |
| US5359100A (en) * | 1987-10-15 | 1994-10-25 | Chiron Corporation | Bifunctional blocked phosphoramidites useful in making nucleic acid mutimers |
| US5124246A (en) * | 1987-10-15 | 1992-06-23 | Chiron Corporation | Nucleic acid multimers and amplified nucleic acid hybridization assays using same |
| US5700637A (en) * | 1988-05-03 | 1997-12-23 | Isis Innovation Limited | Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays |
| US5216141A (en) * | 1988-06-06 | 1993-06-01 | Benner Steven A | Oligonucleotide analogs containing sulfur linkages |
| GB8823869D0 (en) * | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5143854A (en) * | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US5386023A (en) * | 1990-07-27 | 1995-01-31 | Isis Pharmaceuticals | Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling |
| US5602240A (en) * | 1990-07-27 | 1997-02-11 | Ciba Geigy Ag. | Backbone modified oligonucleotide analogs |
| US5545806A (en) * | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5625126A (en) * | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5661016A (en) * | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5633425A (en) * | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| KR100272077B1 (ko) * | 1990-08-29 | 2000-11-15 | 젠팜인터내셔날,인코포레이티드 | 이종 항체를 생산할 수 있는 전이유전자를 가진 인간이외의 동물 |
| US5644048A (en) * | 1992-01-10 | 1997-07-01 | Isis Pharmaceuticals, Inc. | Process for preparing phosphorothioate oligonucleotides |
| US5681697A (en) * | 1993-12-08 | 1997-10-28 | Chiron Corporation | Solution phase nucleic acid sandwich assays having reduced background noise and kits therefor |
| US5637684A (en) * | 1994-02-23 | 1997-06-10 | Isis Pharmaceuticals, Inc. | Phosphoramidate and phosphorothioamidate oligomeric compounds |
| US5580731A (en) * | 1994-08-25 | 1996-12-03 | Chiron Corporation | N-4 modified pyrimidine deoxynucleotides and oligonucleotide probes synthesized therewith |
| US5597909A (en) * | 1994-08-25 | 1997-01-28 | Chiron Corporation | Polynucleotide reagents containing modified deoxyribose moieties, and associated methods of synthesis and use |
| US5681702A (en) * | 1994-08-30 | 1997-10-28 | Chiron Corporation | Reduction of nonspecific hybridization by using novel base-pairing schemes |
| US5759776A (en) * | 1995-06-05 | 1998-06-02 | California Pacific Medical Center | Targets for breast cancer diagnosis and treatment |
| US5776683A (en) * | 1996-07-11 | 1998-07-07 | California Pacific Medical Center | Methods for identifying genes amplified in cancer cells |
| US5928870A (en) * | 1997-06-16 | 1999-07-27 | Exact Laboratories, Inc. | Methods for the detection of loss of heterozygosity |
| US6074825A (en) * | 1997-07-31 | 2000-06-13 | Maine Medical Center | Stable encapsulated reference nucleic acid and method of making |
| US6004528A (en) * | 1997-09-18 | 1999-12-21 | Bergstein; Ivan | Methods of cancer diagnosis and therapy targeted against the cancer stemline |
| US6153441A (en) * | 1998-02-17 | 2000-11-28 | Smithkline Beecham Corporation | Methods of screening for agonists and antagonists for human CCR7 receptor and CKβ-9 ligand and interaction thereof |
| CA2365020C (en) * | 1999-02-24 | 2010-10-19 | Sumitomo Electric Industries, Ltd. | Ganp proteins |
| GB0010191D0 (en) * | 2000-04-26 | 2000-06-14 | Cancer Res Campaign Tech | Assays, methods and means |
| WO2003008583A2 (en) * | 2001-03-02 | 2003-01-30 | Sagres Discovery | Novel compositions and methods for cancer |
-
2002
- 2002-03-20 US US10/105,612 patent/US20030165878A1/en not_active Abandoned
-
2003
- 2003-03-17 EP EP03745117A patent/EP1490690A4/en not_active Withdrawn
- 2003-03-17 WO PCT/US2003/008071 patent/WO2003079977A2/en not_active Ceased
- 2003-03-17 AU AU2003225826A patent/AU2003225826B2/en not_active Ceased
- 2003-03-17 JP JP2003577810A patent/JP2005520536A/ja active Pending
- 2003-03-17 CA CA002479719A patent/CA2479719A1/en not_active Abandoned
-
2006
- 2006-02-17 US US11/357,638 patent/US20060177861A1/en not_active Abandoned
-
2009
- 2009-04-24 JP JP2009107191A patent/JP2009195244A/ja active Pending
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