JP2004533825A5 - - Google Patents
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- Publication number
- JP2004533825A5 JP2004533825A5 JP2002582213A JP2002582213A JP2004533825A5 JP 2004533825 A5 JP2004533825 A5 JP 2004533825A5 JP 2002582213 A JP2002582213 A JP 2002582213A JP 2002582213 A JP2002582213 A JP 2002582213A JP 2004533825 A5 JP2004533825 A5 JP 2004533825A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- patient
- molecule
- cell
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 51
- 210000004027 cell Anatomy 0.000 claims 28
- 101001096065 Homo sapiens Plexin domain-containing protein 1 Proteins 0.000 claims 17
- 101000938391 Homo sapiens Transmembrane protein Proteins 0.000 claims 17
- 102100037891 Plexin domain-containing protein 1 Human genes 0.000 claims 16
- 206010028980 Neoplasm Diseases 0.000 claims 15
- 150000001875 compounds Chemical class 0.000 claims 15
- 238000012360 testing method Methods 0.000 claims 15
- 230000033115 angiogenesis Effects 0.000 claims 12
- 241000124008 Mammalia Species 0.000 claims 10
- 210000002889 endothelial cell Anatomy 0.000 claims 10
- 239000003814 drug Substances 0.000 claims 8
- 229940079593 drug Drugs 0.000 claims 8
- 230000028993 immune response Effects 0.000 claims 8
- 108091026890 Coding region Proteins 0.000 claims 6
- 238000002560 therapeutic procedure Methods 0.000 claims 6
- 230000009134 cell regulation Effects 0.000 claims 5
- 239000003446 ligand Substances 0.000 claims 5
- 206010012689 Diabetic retinopathy Diseases 0.000 claims 4
- 201000004681 Psoriasis Diseases 0.000 claims 4
- 230000001939 inductive effect Effects 0.000 claims 4
- 208000030761 polycystic kidney disease Diseases 0.000 claims 4
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 4
- 230000027455 binding Effects 0.000 claims 3
- 230000002401 inhibitory effect Effects 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 150000007523 nucleic acids Chemical class 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 238000013169 thromboelastometry Methods 0.000 claims 3
- 238000004627 transmission electron microscopy Methods 0.000 claims 3
- 101100425732 Mus musculus Tnmd gene Proteins 0.000 claims 2
- 239000002246 antineoplastic agent Substances 0.000 claims 2
- 210000001124 body fluid Anatomy 0.000 claims 2
- 239000010839 body fluid Substances 0.000 claims 2
- 231100000433 cytotoxic Toxicity 0.000 claims 2
- 230000001472 cytotoxic effect Effects 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 108020004999 messenger RNA Proteins 0.000 claims 2
- 230000009149 molecular binding Effects 0.000 claims 2
- 230000035755 proliferation Effects 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- 108091005703 transmembrane proteins Proteins 0.000 claims 2
- 102000035160 transmembrane proteins Human genes 0.000 claims 2
- 230000004614 tumor growth Effects 0.000 claims 2
- 108020004711 Nucleic Acid Probes Proteins 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 230000003247 decreasing effect Effects 0.000 claims 1
- 210000004443 dendritic cell Anatomy 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 230000004927 fusion Effects 0.000 claims 1
- 238000009396 hybridization Methods 0.000 claims 1
- 239000002853 nucleic acid probe Substances 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28285001P | 2001-04-11 | 2001-04-11 | |
| US35426202P | 2002-02-06 | 2002-02-06 | |
| PCT/US2002/008253 WO2002083874A2 (en) | 2001-04-11 | 2002-04-10 | Endothelial cell expression patterns |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004533825A JP2004533825A (ja) | 2004-11-11 |
| JP2004533825A5 true JP2004533825A5 (enExample) | 2005-12-22 |
Family
ID=26961707
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002582213A Pending JP2004533825A (ja) | 2001-04-11 | 2002-04-10 | 内皮細胞発現パターンの評価法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7393932B2 (enExample) |
| EP (1) | EP1572867B1 (enExample) |
| JP (1) | JP2004533825A (enExample) |
| AU (1) | AU2002258543B2 (enExample) |
| CA (1) | CA2443995C (enExample) |
| WO (1) | WO2002083874A2 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090233270A9 (en) * | 2000-08-02 | 2009-09-17 | St Croix Brad | Secreted and cytoplasmic tumor endothelial markers |
| AU2002239229A1 (en) * | 2000-12-05 | 2002-06-18 | Wisconsin Alumni Research Foundation | Receptor for b. anthracis toxin |
| JP4928259B2 (ja) * | 2003-03-04 | 2012-05-09 | キリンホールディングス株式会社 | 内皮細胞特異的抗体およびその使用 |
| EP1690932A4 (en) * | 2003-10-20 | 2008-03-05 | Teijin Pharma Ltd | ASSOCIATED WITH BONE AND / OR GAP DISEASES GEN |
| WO2006029045A2 (en) * | 2004-09-03 | 2006-03-16 | Kirin Brewery Co., Ltd. | Endothelial cell specific antibodies and uses thereof |
| WO2006091326A1 (en) * | 2005-01-28 | 2006-08-31 | Attogen Inc. | Anti-prl-3 antibodies and methods of use thereof |
| WO2008057632A1 (en) | 2006-11-09 | 2008-05-15 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Differential gene expression in physiological and pathological angiogenesis |
| WO2008101118A2 (en) | 2007-02-14 | 2008-08-21 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | A gene expression signature identifying pro-angiogenic genes in ovarian tumor endothelial cell isolates |
| WO2010007144A2 (en) * | 2008-07-18 | 2010-01-21 | Centre National De La Recherche Scientifique | New mutated netrin 4 proteins, fragments thereof and their uses as drugs |
| WO2010037124A1 (en) | 2008-09-29 | 2010-04-01 | The Trustees Of The University Of Pennsylvania | Tumor vascular marker-targeted vaccines |
| WO2010071938A1 (en) * | 2008-12-24 | 2010-07-01 | Commonwealth Scientific And Industrial Research Organisation | Novel collagen constructs |
| CN103200945B (zh) | 2010-03-24 | 2016-07-06 | 雷克西制药公司 | 眼部症候中的rna干扰 |
| KR102453078B1 (ko) | 2010-03-24 | 2022-10-11 | 피오 파마슈티칼스 코프. | 진피 및 섬유증성 적응증에서의 ｒｎａ 간섭 |
| WO2012174160A1 (en) | 2011-06-14 | 2012-12-20 | The United States Of America , As Represented By The Secretary, Department Of Health And Human Services | Tem8 antibodies, conjugates thereof, and their use |
| KR101358810B1 (ko) * | 2011-12-30 | 2014-02-11 | 한국원자력의학원 | 방사선 피폭 진단용 마커 ｉｇｆｂｐ-5, 그 마커의 발현수준을 측정하는 방사선 피폭 진단용 조성물, 그 조성물을 포함하는 방사선 피폭 진단용 키트, 및 그 마커를 이용한 방사선 피폭을 진단하는 방법 |
| US9765142B2 (en) | 2013-10-11 | 2017-09-19 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | TEM8 antibodies and their use in treatment and detection of tumors |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5695937A (en) | 1995-09-12 | 1997-12-09 | The Johns Hopkins University School Of Medicine | Method for serial analysis of gene expression |
| WO2002010217A2 (en) | 2000-08-02 | 2002-02-07 | The Johns Hopkins University | Endothelial cell expression patterns |
-
2002
- 2002-04-10 CA CA2443995A patent/CA2443995C/en not_active Expired - Lifetime
- 2002-04-10 WO PCT/US2002/008253 patent/WO2002083874A2/en not_active Ceased
- 2002-04-10 EP EP02728495.9A patent/EP1572867B1/en not_active Expired - Lifetime
- 2002-04-10 JP JP2002582213A patent/JP2004533825A/ja active Pending
- 2002-04-10 AU AU2002258543A patent/AU2002258543B2/en not_active Expired
- 2002-04-10 US US10/474,794 patent/US7393932B2/en not_active Expired - Lifetime
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