JP2005526016A5 - - Google Patents
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- Publication number
- JP2005526016A5 JP2005526016A5 JP2003561581A JP2003561581A JP2005526016A5 JP 2005526016 A5 JP2005526016 A5 JP 2005526016A5 JP 2003561581 A JP2003561581 A JP 2003561581A JP 2003561581 A JP2003561581 A JP 2003561581A JP 2005526016 A5 JP2005526016 A5 JP 2005526016A5
- Authority
- JP
- Japan
- Prior art keywords
- dna
- delivery device
- drug delivery
- stabilized
- supercoiled
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000012377 drug delivery Methods 0.000 claims 4
- XEDONBRPTABQFB-UHFFFAOYSA-N 4-[(2-formyl-3-hydroxyphenoxy)methyl]benzoic acid Chemical compound C1=CC(C(=O)O)=CC=C1COC1=CC=CC(O)=C1C=O XEDONBRPTABQFB-UHFFFAOYSA-N 0.000 claims 1
- 102000004127 Cytokines Human genes 0.000 claims 1
- 108090000695 Cytokines Proteins 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- SQQXRXKYTKFFSM-UHFFFAOYSA-N chembl1992147 Chemical compound OC1=C(OC)C(OC)=CC=C1C1=C(C)C(C(O)=O)=NC(C=2N=C3C4=NC(C)(C)N=C4C(OC)=C(O)C3=CC=2)=C1N SQQXRXKYTKFFSM-UHFFFAOYSA-N 0.000 claims 1
- 239000000539 dimer Substances 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 229940124669 imidazoquinoline Drugs 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000178 monomer Substances 0.000 claims 1
- 239000013612 plasmid Substances 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 229950009795 tucaresol Drugs 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0201736.6A GB0201736D0 (en) | 2002-01-25 | 2002-01-25 | DNA dosage forms |
| PCT/GB2003/000282 WO2003061636A2 (en) | 2002-01-25 | 2003-01-23 | Dna dosage forms |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005526016A JP2005526016A (ja) | 2005-09-02 |
| JP2005526016A5 true JP2005526016A5 (https=) | 2006-02-09 |
Family
ID=9929749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003561581A Pending JP2005526016A (ja) | 2002-01-25 | 2003-01-23 | Ｄｎａの投薬形態 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20050080028A1 (https=) |
| EP (1) | EP1467720B1 (https=) |
| JP (1) | JP2005526016A (https=) |
| AT (1) | ATE427105T1 (https=) |
| AU (1) | AU2003202685A1 (https=) |
| CA (1) | CA2473679A1 (https=) |
| DE (1) | DE60326930D1 (https=) |
| ES (1) | ES2322572T3 (https=) |
| GB (1) | GB0201736D0 (https=) |
| WO (1) | WO2003061636A2 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0017999D0 (en) * | 2000-07-21 | 2000-09-13 | Smithkline Beecham Biolog | Novel device |
| US8961477B2 (en) | 2003-08-25 | 2015-02-24 | 3M Innovative Properties Company | Delivery of immune response modifier compounds |
| WO2005042702A2 (en) * | 2003-10-23 | 2005-05-12 | Alza Corporation | Compositions of stabilized dna for coating microprojections |
| US7591806B2 (en) * | 2004-05-18 | 2009-09-22 | Bai Xu | High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances |
| DE602005025138D1 (de) | 2004-08-16 | 2011-01-13 | Fuctional Microstructures Ltd | Verfahren zur herstellung einer mikronadel oder eines mikroimplantats |
| US8043250B2 (en) * | 2005-05-18 | 2011-10-25 | Nanomed Devices, Inc. | High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances |
| US8048017B2 (en) * | 2005-05-18 | 2011-11-01 | Bai Xu | High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances |
| CA2614927A1 (en) * | 2005-07-25 | 2007-02-01 | Nanotechnology Victoria Pty Ltd | Microarray device |
| CA2629193C (en) | 2005-11-18 | 2016-03-29 | 3M Innovative Properties Company | Coatable compositions, coatings derived therefrom and microarrays having such coatings |
| US10525246B2 (en) | 2006-12-22 | 2020-01-07 | Nanomed Skincare, Inc. | Microdevice and method for transdermal delivery and sampling of active substances |
| US20080214987A1 (en) * | 2006-12-22 | 2008-09-04 | Nanomed Devices, Inc. | Microdevice And Method For Transdermal Delivery And Sampling Of Active Substances |
| US8512679B2 (en) | 2011-03-04 | 2013-08-20 | Elwha Llc | Glassy compositions |
| CN103717249B (zh) | 2011-06-15 | 2017-03-22 | 克洛恩泰克制药股份公司 | 注射针和装置 |
| KR101314091B1 (ko) * | 2011-07-26 | 2013-10-04 | 연세대학교 산학협력단 | 치료 부위내 경피 유전자 전달을 위한 일렉트로 마이크로니들 집적체 및 이의 제조방법 |
| JP2013052202A (ja) * | 2011-09-01 | 2013-03-21 | Kosumedei Seiyaku Kk | Ｄｎａワクチンマイクロニードル |
| EP2782603A1 (en) | 2011-11-25 | 2014-10-01 | Danmarks Tekniske Universitet | Formulation of solid nano-sized particles in a gel-forming system |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2017507C (en) * | 1989-05-25 | 1996-11-12 | Gary Van Nest | Adjuvant formulation comprising a submicron oil droplet emulsion |
| DE69034053T2 (de) * | 1989-06-26 | 2003-12-04 | Powderject Vaccines, Inc. | Transformation von tierischen somatischen zellen mittels partikeln |
| US5697901A (en) * | 1989-12-14 | 1997-12-16 | Elof Eriksson | Gene delivery by microneedle injection |
| CA2160878A1 (en) * | 1993-04-19 | 1994-10-27 | Medisorb Technologies International L.P. | Encapsulation of nucleic acids with conjugates that facilitate and target cellular uptake and gene expression |
| US5804566A (en) * | 1993-08-26 | 1998-09-08 | The Regents Of The University Of California | Methods and devices for immunizing a host through administration of naked polynucleotides with encode allergenic peptides |
| EP0714308A4 (en) * | 1993-08-26 | 1998-07-29 | Univ California | METHOD, COMPOSITIONS AND DEVICES FOR THE ADMINISTRATION OF NAKED POLYNUCLEOTIDS, WHICH ENCODE FOR BIOLOGICALLY ACTIVE PEPTIDES |
| ATE252373T1 (de) * | 1994-08-04 | 2003-11-15 | Elan Drug Delivery Ltd | Feste verabreichungssysteme zur gesteuerten freisetzung von darin eingebauten molekülen sowie verfahren zu deren herstellung |
| US6290991B1 (en) * | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
| JP4386965B2 (ja) * | 1996-04-26 | 2009-12-16 | メルク エンド カンパニー インコーポレーテッド | Ｄｎａワクチン製剤 |
| US6697669B2 (en) * | 1998-07-13 | 2004-02-24 | Genetronics, Inc. | Skin and muscle-targeted gene therapy by pulsed electrical field |
| US6713291B2 (en) * | 1999-01-28 | 2004-03-30 | Alan D. King | Electrodes coated with treating agent and uses thereof |
| EP1163024B1 (en) * | 1999-01-28 | 2003-12-17 | Cyto Pulse Sciences, Inc. | Delivery of macromolecules into cells |
| US6743211B1 (en) * | 1999-11-23 | 2004-06-01 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
| US6835184B1 (en) * | 1999-09-24 | 2004-12-28 | Becton, Dickinson And Company | Method and device for abrading skin |
| US20020002136A1 (en) * | 2000-06-28 | 2002-01-03 | Hebert Rolland F. | Salts of glutathione |
| WO2002003961A1 (en) * | 2000-07-07 | 2002-01-17 | Corixa Corporation | Microspheres and adjuvants for dna vaccine delivery |
| GB0017999D0 (en) * | 2000-07-21 | 2000-09-13 | Smithkline Beecham Biolog | Novel device |
| ATE444773T1 (de) * | 2001-04-20 | 2009-10-15 | Alza Corp | Mikroprojektionsanordnung mit einem überzug, der ein vorteilhaftes mittel enthält |
-
2002
- 2002-01-25 GB GBGB0201736.6A patent/GB0201736D0/en not_active Ceased
-
2003
- 2003-01-23 ES ES03701595T patent/ES2322572T3/es not_active Expired - Lifetime
- 2003-01-23 DE DE60326930T patent/DE60326930D1/de not_active Expired - Fee Related
- 2003-01-23 AU AU2003202685A patent/AU2003202685A1/en not_active Abandoned
- 2003-01-23 CA CA002473679A patent/CA2473679A1/en not_active Abandoned
- 2003-01-23 AT AT03701595T patent/ATE427105T1/de not_active IP Right Cessation
- 2003-01-23 EP EP03701595A patent/EP1467720B1/en not_active Expired - Lifetime
- 2003-01-23 US US10/502,285 patent/US20050080028A1/en not_active Abandoned
- 2003-01-23 JP JP2003561581A patent/JP2005526016A/ja active Pending
- 2003-01-23 WO PCT/GB2003/000282 patent/WO2003061636A2/en not_active Ceased
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