JP2005526016A5 - - Google Patents
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- Publication number
- JP2005526016A5 JP2005526016A5 JP2003561581A JP2003561581A JP2005526016A5 JP 2005526016 A5 JP2005526016 A5 JP 2005526016A5 JP 2003561581 A JP2003561581 A JP 2003561581A JP 2003561581 A JP2003561581 A JP 2003561581A JP 2005526016 A5 JP2005526016 A5 JP 2005526016A5
- Authority
- JP
- Japan
- Prior art keywords
- dna
- delivery device
- drug delivery
- stabilized
- supercoiled
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000012377 drug delivery Methods 0.000 claims 4
- XEDONBRPTABQFB-UHFFFAOYSA-N 4-[(2-formyl-3-hydroxyphenoxy)methyl]benzoic acid Chemical compound C1=CC(C(=O)O)=CC=C1COC1=CC=CC(O)=C1C=O XEDONBRPTABQFB-UHFFFAOYSA-N 0.000 claims 1
- 102000004127 Cytokines Human genes 0.000 claims 1
- 108090000695 Cytokines Proteins 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- SQQXRXKYTKFFSM-UHFFFAOYSA-N chembl1992147 Chemical compound OC1=C(OC)C(OC)=CC=C1C1=C(C)C(C(O)=O)=NC(C=2N=C3C4=NC(C)(C)N=C4C(OC)=C(O)C3=CC=2)=C1N SQQXRXKYTKFFSM-UHFFFAOYSA-N 0.000 claims 1
- 239000000539 dimer Substances 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 229940124669 imidazoquinoline Drugs 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000178 monomer Substances 0.000 claims 1
- 239000013612 plasmid Substances 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 229950009795 tucaresol Drugs 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0201736.6A GB0201736D0 (en) | 2002-01-25 | 2002-01-25 | DNA dosage forms |
| PCT/GB2003/000282 WO2003061636A2 (en) | 2002-01-25 | 2003-01-23 | Dna dosage forms |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005526016A JP2005526016A (ja) | 2005-09-02 |
| JP2005526016A5 true JP2005526016A5 (https=) | 2006-02-09 |
Family
ID=9929749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003561581A Pending JP2005526016A (ja) | 2002-01-25 | 2003-01-23 | Ｄｎａの投薬形態 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20050080028A1 (https=) |
| EP (1) | EP1467720B1 (https=) |
| JP (1) | JP2005526016A (https=) |
| AT (1) | ATE427105T1 (https=) |
| AU (1) | AU2003202685A1 (https=) |
| CA (1) | CA2473679A1 (https=) |
| DE (1) | DE60326930D1 (https=) |
| ES (1) | ES2322572T3 (https=) |
| GB (1) | GB0201736D0 (https=) |
| WO (1) | WO2003061636A2 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0017999D0 (en) * | 2000-07-21 | 2000-09-13 | Smithkline Beecham Biolog | Novel device |
| WO2005020912A2 (en) | 2003-08-25 | 2005-03-10 | 3M Innovative Properties Company | Delivery of immune response modifier compounds |
| BRPI0415850A (pt) * | 2003-10-23 | 2007-01-02 | Alza Corp | composição de dna estabilizado para o revestimento de micro projeções |
| US7591806B2 (en) * | 2004-05-18 | 2009-09-22 | Bai Xu | High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances |
| EP2272430A1 (en) | 2004-08-16 | 2011-01-12 | Functional Microstructures Limited | Method of producing a microneedle or microimplant |
| US8048017B2 (en) * | 2005-05-18 | 2011-11-01 | Bai Xu | High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances |
| US8043250B2 (en) * | 2005-05-18 | 2011-10-25 | Nanomed Devices, Inc. | High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances |
| CN101227940A (zh) * | 2005-07-25 | 2008-07-23 | 纳米技术维多利亚有限公司 | 微阵列装置 |
| CA2629193C (en) | 2005-11-18 | 2016-03-29 | 3M Innovative Properties Company | Coatable compositions, coatings derived therefrom and microarrays having such coatings |
| US10525246B2 (en) | 2006-12-22 | 2020-01-07 | Nanomed Skincare, Inc. | Microdevice and method for transdermal delivery and sampling of active substances |
| US20080214987A1 (en) * | 2006-12-22 | 2008-09-04 | Nanomed Devices, Inc. | Microdevice And Method For Transdermal Delivery And Sampling Of Active Substances |
| US8512679B2 (en) | 2011-03-04 | 2013-08-20 | Elwha Llc | Glassy compositions |
| CN103717249B (zh) | 2011-06-15 | 2017-03-22 | 克洛恩泰克制药股份公司 | 注射针和装置 |
| KR101314091B1 (ko) * | 2011-07-26 | 2013-10-04 | 연세대학교 산학협력단 | 치료 부위내 경피 유전자 전달을 위한 일렉트로 마이크로니들 집적체 및 이의 제조방법 |
| JP2013052202A (ja) * | 2011-09-01 | 2013-03-21 | Kosumedei Seiyaku Kk | Ｄｎａワクチンマイクロニードル |
| US10064960B2 (en) * | 2011-11-25 | 2018-09-04 | Danmarks Tekniske Universitet | Formulation of solid nano-sized particles in a gel-forming system |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU212924B (en) * | 1989-05-25 | 1996-12-30 | Chiron Corp | Adjuvant formulation comprising a submicron oil droplet emulsion |
| ATE235558T1 (de) * | 1989-06-26 | 2003-04-15 | Powderject Vaccines Inc | Transformation von tierischen somatischen zellen mittels partikeln |
| US5697901A (en) * | 1989-12-14 | 1997-12-16 | Elof Eriksson | Gene delivery by microneedle injection |
| JPH08510639A (ja) * | 1993-04-19 | 1996-11-12 | メディソーブ・テクノロジーズ・インターナショナル・リミテッド・パートナーシップ | 細胞取込みと遺伝子発現の促進と標的化をもたらす接合体と核酸のカプセル化 |
| US5804566A (en) * | 1993-08-26 | 1998-09-08 | The Regents Of The University Of California | Methods and devices for immunizing a host through administration of naked polynucleotides with encode allergenic peptides |
| AU705889B2 (en) * | 1993-08-26 | 1999-06-03 | Regents Of The University Of California, The | Method, compositions and devices for administration of naked polynucleotides which encode antigens and immunostimulatory peptides |
| US6290991B1 (en) * | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
| ES2208687T3 (es) * | 1994-08-04 | 2004-06-16 | Elan Drug Delivery Limited | Sistema de administracion de sustancias solidas para la liberacion controlada de moleculas incorporadas en tales sustancias y procedimientos para la fabricacion de tales sistemas. |
| EP0906110B1 (en) * | 1996-04-26 | 2004-12-22 | Merck & Co., Inc. | Dna vaccine formulations |
| EP1100579B1 (en) * | 1998-07-13 | 2015-09-02 | Inovio Pharmaceuticals, Inc. | Skin and muscle-targeted gene therapy by pulsed electrical field |
| US6713291B2 (en) * | 1999-01-28 | 2004-03-30 | Alan D. King | Electrodes coated with treating agent and uses thereof |
| EP1163024B1 (en) * | 1999-01-28 | 2003-12-17 | Cyto Pulse Sciences, Inc. | Delivery of macromolecules into cells |
| US6743211B1 (en) * | 1999-11-23 | 2004-06-01 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
| US6835184B1 (en) * | 1999-09-24 | 2004-12-28 | Becton, Dickinson And Company | Method and device for abrading skin |
| US20020002136A1 (en) * | 2000-06-28 | 2002-01-03 | Hebert Rolland F. | Salts of glutathione |
| EP1299087A1 (en) * | 2000-07-07 | 2003-04-09 | Corixa Corporation | Microspheres and adjuvants for dna vaccine delivery |
| GB0017999D0 (en) * | 2000-07-21 | 2000-09-13 | Smithkline Beecham Biolog | Novel device |
| NZ529029A (en) * | 2001-04-20 | 2005-07-29 | Alza Corp | Microprojection array having a beneficial agent containing coating |
-
2002
- 2002-01-25 GB GBGB0201736.6A patent/GB0201736D0/en not_active Ceased
-
2003
- 2003-01-23 CA CA002473679A patent/CA2473679A1/en not_active Abandoned
- 2003-01-23 WO PCT/GB2003/000282 patent/WO2003061636A2/en not_active Ceased
- 2003-01-23 US US10/502,285 patent/US20050080028A1/en not_active Abandoned
- 2003-01-23 EP EP03701595A patent/EP1467720B1/en not_active Expired - Lifetime
- 2003-01-23 DE DE60326930T patent/DE60326930D1/de not_active Expired - Fee Related
- 2003-01-23 AU AU2003202685A patent/AU2003202685A1/en not_active Abandoned
- 2003-01-23 AT AT03701595T patent/ATE427105T1/de not_active IP Right Cessation
- 2003-01-23 JP JP2003561581A patent/JP2005526016A/ja active Pending
- 2003-01-23 ES ES03701595T patent/ES2322572T3/es not_active Expired - Lifetime
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