DE60326930D1 - Darreichungsformen für dna - Google Patents
Darreichungsformen für dnaInfo
- Publication number
- DE60326930D1 DE60326930D1 DE60326930T DE60326930T DE60326930D1 DE 60326930 D1 DE60326930 D1 DE 60326930D1 DE 60326930 T DE60326930 T DE 60326930T DE 60326930 T DE60326930 T DE 60326930T DE 60326930 D1 DE60326930 D1 DE 60326930D1
- Authority
- DE
- Germany
- Prior art keywords
- dna
- skin
- present
- devices
- solid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays or needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0201736.6A GB0201736D0 (en) | 2002-01-25 | 2002-01-25 | DNA dosage forms |
| PCT/GB2003/000282 WO2003061636A2 (en) | 2002-01-25 | 2003-01-23 | Dna dosage forms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60326930D1 true DE60326930D1 (de) | 2009-05-14 |
Family
ID=9929749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60326930T Expired - Fee Related DE60326930D1 (de) | 2002-01-25 | 2003-01-23 | Darreichungsformen für dna |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20050080028A1 (https=) |
| EP (1) | EP1467720B1 (https=) |
| JP (1) | JP2005526016A (https=) |
| AT (1) | ATE427105T1 (https=) |
| AU (1) | AU2003202685A1 (https=) |
| CA (1) | CA2473679A1 (https=) |
| DE (1) | DE60326930D1 (https=) |
| ES (1) | ES2322572T3 (https=) |
| GB (1) | GB0201736D0 (https=) |
| WO (1) | WO2003061636A2 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0017999D0 (en) * | 2000-07-21 | 2000-09-13 | Smithkline Beecham Biolog | Novel device |
| WO2005020912A2 (en) | 2003-08-25 | 2005-03-10 | 3M Innovative Properties Company | Delivery of immune response modifier compounds |
| BRPI0415850A (pt) * | 2003-10-23 | 2007-01-02 | Alza Corp | composição de dna estabilizado para o revestimento de micro projeções |
| US7591806B2 (en) * | 2004-05-18 | 2009-09-22 | Bai Xu | High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances |
| EP2272430A1 (en) | 2004-08-16 | 2011-01-12 | Functional Microstructures Limited | Method of producing a microneedle or microimplant |
| US8048017B2 (en) * | 2005-05-18 | 2011-11-01 | Bai Xu | High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances |
| US8043250B2 (en) * | 2005-05-18 | 2011-10-25 | Nanomed Devices, Inc. | High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances |
| CN101227940A (zh) * | 2005-07-25 | 2008-07-23 | 纳米技术维多利亚有限公司 | 微阵列装置 |
| CA2629193C (en) | 2005-11-18 | 2016-03-29 | 3M Innovative Properties Company | Coatable compositions, coatings derived therefrom and microarrays having such coatings |
| US10525246B2 (en) | 2006-12-22 | 2020-01-07 | Nanomed Skincare, Inc. | Microdevice and method for transdermal delivery and sampling of active substances |
| US20080214987A1 (en) * | 2006-12-22 | 2008-09-04 | Nanomed Devices, Inc. | Microdevice And Method For Transdermal Delivery And Sampling Of Active Substances |
| US8512679B2 (en) | 2011-03-04 | 2013-08-20 | Elwha Llc | Glassy compositions |
| CN103717249B (zh) | 2011-06-15 | 2017-03-22 | 克洛恩泰克制药股份公司 | 注射针和装置 |
| KR101314091B1 (ko) * | 2011-07-26 | 2013-10-04 | 연세대학교 산학협력단 | 치료 부위내 경피 유전자 전달을 위한 일렉트로 마이크로니들 집적체 및 이의 제조방법 |
| JP2013052202A (ja) * | 2011-09-01 | 2013-03-21 | Kosumedei Seiyaku Kk | Ｄｎａワクチンマイクロニードル |
| US10064960B2 (en) * | 2011-11-25 | 2018-09-04 | Danmarks Tekniske Universitet | Formulation of solid nano-sized particles in a gel-forming system |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU212924B (en) * | 1989-05-25 | 1996-12-30 | Chiron Corp | Adjuvant formulation comprising a submicron oil droplet emulsion |
| ATE235558T1 (de) * | 1989-06-26 | 2003-04-15 | Powderject Vaccines Inc | Transformation von tierischen somatischen zellen mittels partikeln |
| US5697901A (en) * | 1989-12-14 | 1997-12-16 | Elof Eriksson | Gene delivery by microneedle injection |
| JPH08510639A (ja) * | 1993-04-19 | 1996-11-12 | メディソーブ・テクノロジーズ・インターナショナル・リミテッド・パートナーシップ | 細胞取込みと遺伝子発現の促進と標的化をもたらす接合体と核酸のカプセル化 |
| US5804566A (en) * | 1993-08-26 | 1998-09-08 | The Regents Of The University Of California | Methods and devices for immunizing a host through administration of naked polynucleotides with encode allergenic peptides |
| AU705889B2 (en) * | 1993-08-26 | 1999-06-03 | Regents Of The University Of California, The | Method, compositions and devices for administration of naked polynucleotides which encode antigens and immunostimulatory peptides |
| US6290991B1 (en) * | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
| ES2208687T3 (es) * | 1994-08-04 | 2004-06-16 | Elan Drug Delivery Limited | Sistema de administracion de sustancias solidas para la liberacion controlada de moleculas incorporadas en tales sustancias y procedimientos para la fabricacion de tales sistemas. |
| EP0906110B1 (en) * | 1996-04-26 | 2004-12-22 | Merck & Co., Inc. | Dna vaccine formulations |
| EP1100579B1 (en) * | 1998-07-13 | 2015-09-02 | Inovio Pharmaceuticals, Inc. | Skin and muscle-targeted gene therapy by pulsed electrical field |
| US6713291B2 (en) * | 1999-01-28 | 2004-03-30 | Alan D. King | Electrodes coated with treating agent and uses thereof |
| EP1163024B1 (en) * | 1999-01-28 | 2003-12-17 | Cyto Pulse Sciences, Inc. | Delivery of macromolecules into cells |
| US6743211B1 (en) * | 1999-11-23 | 2004-06-01 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
| US6835184B1 (en) * | 1999-09-24 | 2004-12-28 | Becton, Dickinson And Company | Method and device for abrading skin |
| US20020002136A1 (en) * | 2000-06-28 | 2002-01-03 | Hebert Rolland F. | Salts of glutathione |
| EP1299087A1 (en) * | 2000-07-07 | 2003-04-09 | Corixa Corporation | Microspheres and adjuvants for dna vaccine delivery |
| GB0017999D0 (en) * | 2000-07-21 | 2000-09-13 | Smithkline Beecham Biolog | Novel device |
| NZ529029A (en) * | 2001-04-20 | 2005-07-29 | Alza Corp | Microprojection array having a beneficial agent containing coating |
-
2002
- 2002-01-25 GB GBGB0201736.6A patent/GB0201736D0/en not_active Ceased
-
2003
- 2003-01-23 CA CA002473679A patent/CA2473679A1/en not_active Abandoned
- 2003-01-23 WO PCT/GB2003/000282 patent/WO2003061636A2/en not_active Ceased
- 2003-01-23 US US10/502,285 patent/US20050080028A1/en not_active Abandoned
- 2003-01-23 EP EP03701595A patent/EP1467720B1/en not_active Expired - Lifetime
- 2003-01-23 DE DE60326930T patent/DE60326930D1/de not_active Expired - Fee Related
- 2003-01-23 AU AU2003202685A patent/AU2003202685A1/en not_active Abandoned
- 2003-01-23 AT AT03701595T patent/ATE427105T1/de not_active IP Right Cessation
- 2003-01-23 JP JP2003561581A patent/JP2005526016A/ja active Pending
- 2003-01-23 ES ES03701595T patent/ES2322572T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1467720A2 (en) | 2004-10-20 |
| ATE427105T1 (de) | 2009-04-15 |
| US20050080028A1 (en) | 2005-04-14 |
| ES2322572T3 (es) | 2009-06-23 |
| EP1467720B1 (en) | 2009-04-01 |
| WO2003061636A3 (en) | 2003-11-27 |
| CA2473679A1 (en) | 2003-07-31 |
| GB0201736D0 (en) | 2002-03-13 |
| AU2003202685A1 (en) | 2003-09-02 |
| WO2003061636A2 (en) | 2003-07-31 |
| JP2005526016A (ja) | 2005-09-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |