JP2005525128A5 - - Google Patents
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- JP2005525128A5 JP2005525128A5 JP2004530731A JP2004530731A JP2005525128A5 JP 2005525128 A5 JP2005525128 A5 JP 2005525128A5 JP 2004530731 A JP2004530731 A JP 2004530731A JP 2004530731 A JP2004530731 A JP 2004530731A JP 2005525128 A5 JP2005525128 A5 JP 2005525128A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- tcr
- vector
- cloned
- domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29632401P | 2001-06-05 | 2001-06-05 | |
| PCT/US2002/017785 WO2004018619A2 (en) | 2001-06-05 | 2002-06-05 | P53 binding t cell receptor molecules and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005525128A JP2005525128A (ja) | 2005-08-25 |
| JP2005525128A5 true JP2005525128A5 (enExample) | 2006-01-05 |
| JP4447456B2 JP4447456B2 (ja) | 2010-04-07 |
Family
ID=31946570
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004530731A Expired - Lifetime JP4447456B2 (ja) | 2001-06-05 | 2002-06-05 | Ｐ５３結合ｔ細胞受容体分子とその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7456263B2 (enExample) |
| EP (2) | EP2009019A1 (enExample) |
| JP (1) | JP4447456B2 (enExample) |
| CN (1) | CN1692124B (enExample) |
| AT (1) | ATE405582T1 (enExample) |
| AU (1) | AU2002316190B8 (enExample) |
| CA (1) | CA2487779C (enExample) |
| DE (1) | DE60228504D1 (enExample) |
| DK (1) | DK1546188T3 (enExample) |
| ES (1) | ES2307770T3 (enExample) |
| WO (1) | WO2004018619A2 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030144474A1 (en) * | 2000-06-05 | 2003-07-31 | Sunol Molecular Corporation | T cell receptor fusions and conjugates and methods of use thereof |
| US8772451B2 (en) * | 2003-11-10 | 2014-07-08 | Altor Bioscience Corporation | Soluble TCR molecules and methods of use |
| US7994298B2 (en) | 2004-09-24 | 2011-08-09 | Trustees Of Dartmouth College | Chimeric NK receptor and methods for treating cancer |
| US10464987B2 (en) | 2009-10-06 | 2019-11-05 | Abbvie Inc. | Human single-chain T cell receptors |
| US12492376B2 (en) | 2009-10-29 | 2025-12-09 | The Trustees Of Dartmouth College | T-cell receptor-deficient T cell compositions |
| US9273283B2 (en) | 2009-10-29 | 2016-03-01 | The Trustees Of Dartmouth College | Method of producing T cell receptor-deficient T cells expressing a chimeric receptor |
| WO2011059836A2 (en) | 2009-10-29 | 2011-05-19 | Trustees Of Dartmouth College | T cell receptor-deficient t cell compositions |
| US9833476B2 (en) | 2011-08-31 | 2017-12-05 | The Trustees Of Dartmouth College | NKP30 receptor targeted therapeutics |
| WO2013169691A1 (en) | 2012-05-07 | 2013-11-14 | Trustees Of Dartmouth College | Anti-b7-h6 antibody, fusion proteins, and methods of using the same |
| UA114108C2 (uk) | 2012-07-10 | 2017-04-25 | Борд Оф Ріджентс, Дзе Юніверсіті Оф Техас Сістем | Моноклональне антитіло для застосування в діагностиці і терапії злоякісних пухлин і аутоімунного захворювання |
| US11939365B2 (en) * | 2017-09-29 | 2024-03-26 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | T cell receptors recognizing mutated P53 |
| EP3692058A1 (en) | 2017-10-06 | 2020-08-12 | Oslo Universitetssykehus HF | Chimeric antigen receptors |
| CN108060135A (zh) * | 2017-12-26 | 2018-05-22 | 东莞赛尔生物科技有限公司 | 一种高效表达p53抑癌蛋白的t细胞、制备方法及应用 |
| WO2019195586A1 (en) | 2018-04-06 | 2019-10-10 | The Regents Of The University Of California | Methods of treating egfrviii expressing glioblastomas |
| US12090170B2 (en) | 2018-04-06 | 2024-09-17 | The Regents Of The University Of California | Methods of treating glioblastomas |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4867973A (en) | 1984-08-31 | 1989-09-19 | Cytogen Corporation | Antibody-therapeutic agent conjugates |
| US5057313A (en) | 1986-02-25 | 1991-10-15 | The Center For Molecular Medicine And Immunology | Diagnostic and therapeutic antibody conjugates |
| WO1988007553A1 (fr) | 1987-03-26 | 1988-10-06 | Teijin Limited | Procede de preparation d'un complexe d'anticorps |
| EP0515527A4 (en) | 1990-02-20 | 1993-08-25 | Coulter Corporation | Improved antibody-enzyme direct conjugates and method of making same |
| GB9200417D0 (en) | 1992-01-09 | 1992-02-26 | Bagshawe Kenneth D | Cytotoxic drug therapy |
| US6399368B1 (en) | 1992-01-17 | 2002-06-04 | Board Of Regents, The University Of Texas System | Secretion of T cell receptor fragments from recombinant Escherichia coli cells |
| ES2139012T3 (es) * | 1992-05-26 | 2000-02-01 | Univ Leiden | Peptidos de la proteina p53 humana destinados para ser utilizados en composiciones que inducen una reaccion en los linfocitos t humanos, y linfocitos t citotoxicos especificos de la proteina p53 humana. |
| WO1994012520A1 (en) | 1992-11-20 | 1994-06-09 | Enzon, Inc. | Linker for linked fusion polypeptides |
| CA2196085C (en) | 1994-07-29 | 2002-12-10 | Hing C. Wong | Mhc complexes and uses thereof |
| WO1996013593A2 (en) | 1994-10-26 | 1996-05-09 | Procept, Inc. | Soluble single chain t cell receptors |
| JPH10510988A (ja) * | 1994-12-14 | 1998-10-27 | ザ スクリップス リサーチ インスティテュート | 腫瘍−特異的細胞毒性ｔ細胞のインビボ活性化 |
| US5830755A (en) | 1995-03-27 | 1998-11-03 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | T-cell receptors and their use in therapeutic and diagnostic methods |
| US5869270A (en) | 1996-01-31 | 1999-02-09 | Sunol Molecular Corporation | Single chain MHC complexes and uses thereof |
| WO1997032603A1 (en) | 1996-03-05 | 1997-09-12 | The Scripps Research Institute | Recombinant constructs encoding t cell receptors specific for human hla-restricted tumor antigens |
| US6127524A (en) | 1996-10-18 | 2000-10-03 | Dade Behring Inc. | Binding molecules and computer-based methods of increasing the binding affinity thereof |
| AU6685698A (en) | 1997-03-07 | 1998-09-22 | Sunol Molecular Corporation | Fusion proteins comprising bacteriophage coat protein and a single-chain t cell receptor |
| ATE533784T1 (de) | 1997-10-02 | 2011-12-15 | Altor Bioscience Corp | Lösliche, einzelkettige proteine des t- zellrezeptors |
| US6534633B1 (en) | 1998-10-21 | 2003-03-18 | Altor Bioscience Corporation | Polyspecific binding molecules and uses thereof |
| WO2001090747A2 (en) | 2000-05-25 | 2001-11-29 | Sunol Molecular Corporation | Modulation of t-cell receptor interactions |
| US20030144474A1 (en) | 2000-06-05 | 2003-07-31 | Sunol Molecular Corporation | T cell receptor fusions and conjugates and methods of use thereof |
| DE10109855A1 (de) * | 2001-03-01 | 2002-09-12 | Stanislawski Thomas | Polypeptide eines p53-Protein-spezifischen murinen alpha/beta T-Zell Rezeptors, diese kodierende Nukleinsäuren und deren Verwendung |
-
2002
- 2002-06-05 JP JP2004530731A patent/JP4447456B2/ja not_active Expired - Lifetime
- 2002-06-05 US US10/163,084 patent/US7456263B2/en not_active Expired - Lifetime
- 2002-06-05 AU AU2002316190A patent/AU2002316190B8/en not_active Expired
- 2002-06-05 EP EP08012635A patent/EP2009019A1/en not_active Withdrawn
- 2002-06-05 CN CN028153030A patent/CN1692124B/zh not_active Expired - Lifetime
- 2002-06-05 WO PCT/US2002/017785 patent/WO2004018619A2/en not_active Ceased
- 2002-06-05 EP EP02746470A patent/EP1546188B1/en not_active Expired - Lifetime
- 2002-06-05 ES ES02746470T patent/ES2307770T3/es not_active Expired - Lifetime
- 2002-06-05 CA CA2487779A patent/CA2487779C/en not_active Expired - Lifetime
- 2002-06-05 AT AT02746470T patent/ATE405582T1/de active
- 2002-06-05 DE DE60228504T patent/DE60228504D1/de not_active Expired - Lifetime
- 2002-06-05 DK DK02746470T patent/DK1546188T3/da active
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