JP2005525128A5 - - Google Patents
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- Publication number
- JP2005525128A5 JP2005525128A5 JP2004530731A JP2004530731A JP2005525128A5 JP 2005525128 A5 JP2005525128 A5 JP 2005525128A5 JP 2004530731 A JP2004530731 A JP 2004530731A JP 2004530731 A JP2004530731 A JP 2004530731A JP 2005525128 A5 JP2005525128 A5 JP 2005525128A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- tcr
- vector
- cloned
- domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29632401P | 2001-06-05 | 2001-06-05 | |
| PCT/US2002/017785 WO2004018619A2 (en) | 2001-06-05 | 2002-06-05 | P53 binding t cell receptor molecules and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005525128A JP2005525128A (ja) | 2005-08-25 |
| JP2005525128A5 true JP2005525128A5 (enExample) | 2006-01-05 |
| JP4447456B2 JP4447456B2 (ja) | 2010-04-07 |
Family
ID=31946570
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004530731A Expired - Lifetime JP4447456B2 (ja) | 2001-06-05 | 2002-06-05 | Ｐ５３結合ｔ細胞受容体分子とその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7456263B2 (enExample) |
| EP (2) | EP1546188B1 (enExample) |
| JP (1) | JP4447456B2 (enExample) |
| CN (1) | CN1692124B (enExample) |
| AT (1) | ATE405582T1 (enExample) |
| AU (1) | AU2002316190B8 (enExample) |
| CA (1) | CA2487779C (enExample) |
| DE (1) | DE60228504D1 (enExample) |
| DK (1) | DK1546188T3 (enExample) |
| ES (1) | ES2307770T3 (enExample) |
| WO (1) | WO2004018619A2 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2322228B1 (en) * | 2000-06-05 | 2018-01-10 | Altor BioScience Corporation | T cell receptor fusion proteins and conjugates and methods of use thereof |
| KR101131297B1 (ko) | 2003-11-10 | 2012-03-30 | 알토 바이오사이언스 코포레이션 | 가용성 티씨알 분자 및 이용 방법 |
| WO2006036445A2 (en) | 2004-09-24 | 2006-04-06 | Trustees Of Dartmouth College | Chimeric nk receptor and methods for treating cancer |
| WO2011044186A1 (en) | 2009-10-06 | 2011-04-14 | The Board Of Trustees Of The University Of Illinois | Human single-chain t cell receptors |
| US9273283B2 (en) | 2009-10-29 | 2016-03-01 | The Trustees Of Dartmouth College | Method of producing T cell receptor-deficient T cells expressing a chimeric receptor |
| WO2011059836A2 (en) | 2009-10-29 | 2011-05-19 | Trustees Of Dartmouth College | T cell receptor-deficient t cell compositions |
| US12492376B2 (en) | 2009-10-29 | 2025-12-09 | The Trustees Of Dartmouth College | T-cell receptor-deficient T cell compositions |
| US9833476B2 (en) | 2011-08-31 | 2017-12-05 | The Trustees Of Dartmouth College | NKP30 receptor targeted therapeutics |
| CN104395344B (zh) | 2012-05-07 | 2019-08-13 | 达特茅斯大学理事会 | 抗b7-h6抗体、融合蛋白及其使用方法 |
| UA114108C2 (uk) | 2012-07-10 | 2017-04-25 | Борд Оф Ріджентс, Дзе Юніверсіті Оф Техас Сістем | Моноклональне антитіло для застосування в діагностиці і терапії злоякісних пухлин і аутоімунного захворювання |
| IL273515B2 (en) * | 2017-09-29 | 2026-03-01 | Us Health | T cell receptors that recognize mutated P53 |
| WO2019069125A1 (en) | 2017-10-06 | 2019-04-11 | Oslo Universitetssykehus Hf | CHIMERIC ANTIGEN RECEPTORS |
| CN108060135A (zh) * | 2017-12-26 | 2018-05-22 | 东莞赛尔生物科技有限公司 | 一种高效表达p53抑癌蛋白的t细胞、制备方法及应用 |
| CA3096202A1 (en) | 2018-04-06 | 2019-10-10 | The Regents Of The University Of California | Methods of treating egfrviii expressing glioblastomas |
| EP3773633A4 (en) | 2018-04-06 | 2022-01-26 | The Regents of The University of California | METHODS OF TREATMENT OF GLIOBLASTOMA |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4867973A (en) | 1984-08-31 | 1989-09-19 | Cytogen Corporation | Antibody-therapeutic agent conjugates |
| US5057313A (en) | 1986-02-25 | 1991-10-15 | The Center For Molecular Medicine And Immunology | Diagnostic and therapeutic antibody conjugates |
| WO1988007553A1 (fr) | 1987-03-26 | 1988-10-06 | Teijin Limited | Procede de preparation d'un complexe d'anticorps |
| CA2076347C (en) | 1990-02-20 | 1996-11-26 | Ravinder K. Gupta | Improved antibody-enzyme direct conjugates and method of making same |
| GB9200417D0 (en) | 1992-01-09 | 1992-02-26 | Bagshawe Kenneth D | Cytotoxic drug therapy |
| US6399368B1 (en) | 1992-01-17 | 2002-06-04 | Board Of Regents, The University Of Texas System | Secretion of T cell receptor fragments from recombinant Escherichia coli cells |
| CA2136624A1 (en) * | 1992-05-26 | 1993-12-09 | Cornelis J. M. Melief | Peptides of human p53 protein for use in human t cell response inducing compositions, and human p53 protein-specific cytotoxic t-lymphocytes |
| WO1994012520A1 (en) | 1992-11-20 | 1994-06-09 | Enzon, Inc. | Linker for linked fusion polypeptides |
| DK0776339T4 (da) | 1994-07-29 | 2010-05-25 | Sunol Molecular Corp | MHC-komplekser og anvendelser deraf |
| WO1996013593A2 (en) | 1994-10-26 | 1996-05-09 | Procept, Inc. | Soluble single chain t cell receptors |
| AU712441B2 (en) * | 1994-12-14 | 1999-11-04 | Scripps Research Institute, The | In vivo activation of tumor-specific cytotoxic T cells |
| US5830755A (en) | 1995-03-27 | 1998-11-03 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | T-cell receptors and their use in therapeutic and diagnostic methods |
| US5869270A (en) | 1996-01-31 | 1999-02-09 | Sunol Molecular Corporation | Single chain MHC complexes and uses thereof |
| EP0910409A4 (en) | 1996-03-05 | 2003-03-19 | Scripps Research Inst | RECOMBINANT GENE CONSTRUCTS ENCODING T-CELL RECEPTORS SPECIFIC TO HUMAN-RESTRICTED TUMORANTANTIGENS |
| US6127524A (en) | 1996-10-18 | 2000-10-03 | Dade Behring Inc. | Binding molecules and computer-based methods of increasing the binding affinity thereof |
| WO1998039482A1 (en) | 1997-03-07 | 1998-09-11 | Sunol Molecular Corporation | Fusion proteins comprising bacteriophage coat protein and a single-chain t cell receptor |
| CA2305630C (en) | 1997-10-02 | 2012-11-06 | Sunol Molecular Corporation | Soluble single-chain t-cell receptor proteins |
| EP1124568B1 (en) | 1998-10-21 | 2007-08-22 | Altor BioScience Corporation | Polyspecific binding molecules and uses thereof |
| CN1430728A (zh) | 2000-05-25 | 2003-07-16 | 苏诺尔分子公司 | T细胞受体交互作用的调节 |
| EP2322228B1 (en) | 2000-06-05 | 2018-01-10 | Altor BioScience Corporation | T cell receptor fusion proteins and conjugates and methods of use thereof |
| DE10109855A1 (de) * | 2001-03-01 | 2002-09-12 | Stanislawski Thomas | Polypeptide eines p53-Protein-spezifischen murinen alpha/beta T-Zell Rezeptors, diese kodierende Nukleinsäuren und deren Verwendung |
-
2002
- 2002-06-05 WO PCT/US2002/017785 patent/WO2004018619A2/en not_active Ceased
- 2002-06-05 CA CA2487779A patent/CA2487779C/en not_active Expired - Lifetime
- 2002-06-05 DE DE60228504T patent/DE60228504D1/de not_active Expired - Lifetime
- 2002-06-05 EP EP02746470A patent/EP1546188B1/en not_active Expired - Lifetime
- 2002-06-05 ES ES02746470T patent/ES2307770T3/es not_active Expired - Lifetime
- 2002-06-05 AT AT02746470T patent/ATE405582T1/de active
- 2002-06-05 CN CN028153030A patent/CN1692124B/zh not_active Expired - Lifetime
- 2002-06-05 EP EP08012635A patent/EP2009019A1/en not_active Withdrawn
- 2002-06-05 JP JP2004530731A patent/JP4447456B2/ja not_active Expired - Lifetime
- 2002-06-05 AU AU2002316190A patent/AU2002316190B8/en not_active Expired
- 2002-06-05 DK DK02746470T patent/DK1546188T3/da active
- 2002-06-05 US US10/163,084 patent/US7456263B2/en not_active Expired - Lifetime
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