JP2005523049A5 - - Google Patents
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- JP2005523049A5 JP2005523049A5 JP2003563611A JP2003563611A JP2005523049A5 JP 2005523049 A5 JP2005523049 A5 JP 2005523049A5 JP 2003563611 A JP2003563611 A JP 2003563611A JP 2003563611 A JP2003563611 A JP 2003563611A JP 2005523049 A5 JP2005523049 A5 JP 2005523049A5
- Authority
- JP
- Japan
- Prior art keywords
- medical device
- biologically active
- active substance
- central portion
- struts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 229940088623 biologically active substance Drugs 0.000 claims 20
- 239000011149 active material Substances 0.000 claims 6
- 239000011159 matrix material Substances 0.000 claims 6
- 238000000034 method Methods 0.000 claims 6
- 239000011248 coating agent Substances 0.000 claims 5
- 238000000576 coating method Methods 0.000 claims 5
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 claims 4
- 239000011148 porous material Substances 0.000 claims 4
- 239000010410 layer Substances 0.000 claims 3
- 239000000463 material Substances 0.000 claims 3
- 108010092160 Dactinomycin Proteins 0.000 claims 2
- HKVAMNSJSFKALM-GKUWKFKPSA-N Everolimus Chemical compound C1C[C@@H](OCCO)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 HKVAMNSJSFKALM-GKUWKFKPSA-N 0.000 claims 2
- 229930012538 Paclitaxel Natural products 0.000 claims 2
- QJJXYPPXXYFBGM-LFZNUXCKSA-N Tacrolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1\C=C(/C)[C@@H]1[C@H](C)[C@@H](O)CC(=O)[C@H](CC=C)/C=C(C)/C[C@H](C)C[C@H](OC)[C@H]([C@H](C[C@H]2C)OC)O[C@@]2(O)C(=O)C(=O)N2CCCC[C@H]2C(=O)O1 QJJXYPPXXYFBGM-LFZNUXCKSA-N 0.000 claims 2
- 229930183665 actinomycin Natural products 0.000 claims 2
- 230000004888 barrier function Effects 0.000 claims 2
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 claims 2
- 229960003957 dexamethasone Drugs 0.000 claims 2
- 229960005167 everolimus Drugs 0.000 claims 2
- LVASCWIMLIKXLA-LSDHHAIUSA-N halofuginone Chemical compound O[C@@H]1CCCN[C@H]1CC(=O)CN1C(=O)C2=CC(Cl)=C(Br)C=C2N=C1 LVASCWIMLIKXLA-LSDHHAIUSA-N 0.000 claims 2
- 229950010152 halofuginone Drugs 0.000 claims 2
- 230000002209 hydrophobic effect Effects 0.000 claims 2
- 229960001592 paclitaxel Drugs 0.000 claims 2
- ZAHRKKWIAAJSAO-UHFFFAOYSA-N rapamycin Natural products COCC(O)C(=C/C(C)C(=O)CC(OC(=O)C1CCCCN1C(=O)C(=O)C2(O)OC(CC(OC)C(=CC=CC=CC(C)CC(C)C(=O)C)C)CCC2C)C(C)CC3CCC(O)C(C3)OC)C ZAHRKKWIAAJSAO-UHFFFAOYSA-N 0.000 claims 2
- QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 claims 2
- 229960002930 sirolimus Drugs 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 229960001967 tacrolimus Drugs 0.000 claims 2
- QJJXYPPXXYFBGM-SHYZHZOCSA-N tacrolimus Natural products CO[C@H]1C[C@H](CC[C@@H]1O)C=C(C)[C@H]2OC(=O)[C@H]3CCCCN3C(=O)C(=O)[C@@]4(O)O[C@@H]([C@H](C[C@H]4C)OC)[C@@H](C[C@H](C)CC(=C[C@@H](CC=C)C(=O)C[C@H](O)[C@H]2C)C)OC QJJXYPPXXYFBGM-SHYZHZOCSA-N 0.000 claims 2
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims 2
- 239000011247 coating layer Substances 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/062,794 US7291165B2 (en) | 2002-01-31 | 2002-01-31 | Medical device for delivering biologically active material |
| PCT/US2003/002585 WO2003063924A1 (en) | 2002-01-31 | 2003-01-30 | Medical device for delivering biologically active material |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005523049A JP2005523049A (ja) | 2005-08-04 |
| JP2005523049A5 true JP2005523049A5 (enExample) | 2006-05-11 |
Family
ID=27610351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003563611A Pending JP2005523049A (ja) | 2002-01-31 | 2003-01-30 | 生物学的に活性な物質を放出するための医療用デバイス |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7291165B2 (enExample) |
| EP (1) | EP1485138A4 (enExample) |
| JP (1) | JP2005523049A (enExample) |
| AU (1) | AU2003219687B2 (enExample) |
| CA (1) | CA2474243C (enExample) |
| NZ (1) | NZ534508A (enExample) |
| WO (1) | WO2003063924A1 (enExample) |
Families Citing this family (77)
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| US7014654B2 (en) * | 2001-11-30 | 2006-03-21 | Scimed Life Systems, Inc. | Stent designed for the delivery of therapeutic substance or other agents |
| US6981985B2 (en) * | 2002-01-22 | 2006-01-03 | Boston Scientific Scimed, Inc. | Stent bumper struts |
| EP1348402A1 (en) * | 2002-03-29 | 2003-10-01 | Advanced Laser Applications Holding S.A. | Intraluminal endoprosthesis, radially expandable, perforated for drug delivery |
| US20050230039A1 (en) * | 2004-04-19 | 2005-10-20 | Michael Austin | Stent with protective pads or bulges |
-
2002
- 2002-01-31 US US10/062,794 patent/US7291165B2/en not_active Expired - Lifetime
-
2003
- 2003-01-30 CA CA2474243A patent/CA2474243C/en not_active Expired - Fee Related
- 2003-01-30 EP EP03715955A patent/EP1485138A4/en not_active Withdrawn
- 2003-01-30 WO PCT/US2003/002585 patent/WO2003063924A1/en not_active Ceased
- 2003-01-30 NZ NZ534508A patent/NZ534508A/en unknown
- 2003-01-30 JP JP2003563611A patent/JP2005523049A/ja active Pending
- 2003-01-30 AU AU2003219687A patent/AU2003219687B2/en not_active Ceased
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