JP2005522226A5 - - Google Patents

Info

Publication number

JP2005522226A5

JP2005522226A5 JP2003584724A JP2003584724A JP2005522226A5 JP 2005522226 A5 JP2005522226 A5 JP 2005522226A5 JP 2003584724 A JP2003584724 A JP 2003584724A JP 2003584724 A JP2003584724 A JP 2003584724A JP 2005522226 A5 JP2005522226 A5 JP 2005522226A5

Authority

JP

Japan

Prior art keywords

cancer

polypeptide

raig1

expression

nucleic acid

Prior art date

2003-04-10

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
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• 108090000765 processed proteins & peptides Proteins 0.000 claims 22
• 229920001184 polypeptide Polymers 0.000 claims 21
• 102000004196 processed proteins & peptides Human genes 0.000 claims 21
• 101001100101 Homo sapiens Retinoic acid-induced protein 3 Proteins 0.000 claims 17
• 102100038453 Retinoic acid-induced protein 3 Human genes 0.000 claims 17
• 108020004707 nucleic acids Proteins 0.000 claims 15
• 102000039446 nucleic acids Human genes 0.000 claims 15
• 150000007523 nucleic acids Chemical class 0.000 claims 15
• 239000000126 substance Substances 0.000 claims 12
• 206010028980 Neoplasm Diseases 0.000 claims 10
• 201000011510 cancer Diseases 0.000 claims 10
• 239000000203 mixture Substances 0.000 claims 10
• 230000000694 effects Effects 0.000 claims 9
• 238000000034 method Methods 0.000 claims 9
• 239000012634 fragment Substances 0.000 claims 7
• 125000003275 alpha amino acid group Chemical group 0.000 claims 6
• 239000003153 chemical reaction reagent Substances 0.000 claims 6
• 238000012216 screening Methods 0.000 claims 4
• 206010006187 Breast cancer Diseases 0.000 claims 3
• 208000026310 Breast neoplasm Diseases 0.000 claims 3
• 206010009944 Colon cancer Diseases 0.000 claims 3
• 206010058467 Lung neoplasm malignant Diseases 0.000 claims 3
• 206010033128 Ovarian cancer Diseases 0.000 claims 3
• 206010061535 Ovarian neoplasm Diseases 0.000 claims 3
• 206010061902 Pancreatic neoplasm Diseases 0.000 claims 3
• 239000002246 antineoplastic agent Substances 0.000 claims 3
• 208000029742 colonic neoplasm Diseases 0.000 claims 3
• 230000000295 complement effect Effects 0.000 claims 3
• 239000003814 drug Substances 0.000 claims 3
• 201000007270 liver cancer Diseases 0.000 claims 3
• 208000014018 liver neoplasm Diseases 0.000 claims 3
• 201000005202 lung cancer Diseases 0.000 claims 3
• 208000020816 lung neoplasm Diseases 0.000 claims 3
• 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 3
• 238000004519 manufacturing process Methods 0.000 claims 3
• 201000008968 osteosarcoma Diseases 0.000 claims 3
• 201000002528 pancreatic cancer Diseases 0.000 claims 3
• 208000008443 pancreatic carcinoma Diseases 0.000 claims 3
• 230000001225 therapeutic effect Effects 0.000 claims 3
• 102000004127 Cytokines Human genes 0.000 claims 2
• 108090000695 Cytokines Proteins 0.000 claims 2
• 238000009007 Diagnostic Kit Methods 0.000 claims 2
• 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
• 150000001413 amino acids Chemical class 0.000 claims 2
• 239000002254 cytotoxic agent Substances 0.000 claims 2
• 229940127089 cytotoxic agent Drugs 0.000 claims 2
• 231100000599 cytotoxic agent Toxicity 0.000 claims 2
• 238000012217 deletion Methods 0.000 claims 2
• 230000037430 deletion Effects 0.000 claims 2
• 238000001514 detection method Methods 0.000 claims 2
• 238000003745 diagnosis Methods 0.000 claims 2
• 238000003780 insertion Methods 0.000 claims 2
• 230000037431 insertion Effects 0.000 claims 2
• 238000012544 monitoring process Methods 0.000 claims 2
• 238000006467 substitution reaction Methods 0.000 claims 2
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
• 230000003993 interaction Effects 0.000 claims 1
• 238000012986 modification Methods 0.000 claims 1
• 230000004048 modification Effects 0.000 claims 1
• 239000002773 nucleotide Substances 0.000 claims 1
• 125000003729 nucleotide group Chemical group 0.000 claims 1
• 239000008194 pharmaceutical composition Substances 0.000 claims 1
• 230000000069 prophylactic effect Effects 0.000 claims 1
• 239000007790 solid phase Substances 0.000 claims 1
• 238000012360 testing method Methods 0.000 claims 1
• 229960005486 vaccine Drugs 0.000 claims 1