JP2011518773A5 - - Google Patents

Download PDF

Info

Publication number
JP2011518773A5
JP2011518773A5 JP2011500800A JP2011500800A JP2011518773A5 JP 2011518773 A5 JP2011518773 A5 JP 2011518773A5 JP 2011500800 A JP2011500800 A JP 2011500800A JP 2011500800 A JP2011500800 A JP 2011500800A JP 2011518773 A5 JP2011518773 A5 JP 2011518773A5
Authority
JP
Japan
Prior art keywords
seq
antibody
subject
composition
hcc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2011500800A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011518773A (ja
JP5882732B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2009/001689 external-priority patent/WO2009117096A1/en
Publication of JP2011518773A publication Critical patent/JP2011518773A/ja
Publication of JP2011518773A5 publication Critical patent/JP2011518773A5/ja
Application granted granted Critical
Publication of JP5882732B2 publication Critical patent/JP5882732B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2011500800A 2008-03-19 2009-03-18 肝細胞癌の診断および治療のための方法および作用物質 Active JP5882732B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6991008P 2008-03-19 2008-03-19
US61/069,910 2008-03-19
PCT/US2009/001689 WO2009117096A1 (en) 2008-03-19 2009-03-18 Methods and agents for the diagnosis and treatment of hepatocellular carcinoma

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014226127A Division JP6073850B2 (ja) 2008-03-19 2014-11-06 肝細胞癌の診断および治療のための方法および作用物質

Publications (3)

Publication Number Publication Date
JP2011518773A JP2011518773A (ja) 2011-06-30
JP2011518773A5 true JP2011518773A5 (enExample) 2012-02-23
JP5882732B2 JP5882732B2 (ja) 2016-03-09

Family

ID=40810188

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2011500800A Active JP5882732B2 (ja) 2008-03-19 2009-03-18 肝細胞癌の診断および治療のための方法および作用物質
JP2014226127A Active JP6073850B2 (ja) 2008-03-19 2014-11-06 肝細胞癌の診断および治療のための方法および作用物質

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014226127A Active JP6073850B2 (ja) 2008-03-19 2014-11-06 肝細胞癌の診断および治療のための方法および作用物質

Country Status (13)

Country Link
US (4) US8815240B2 (enExample)
EP (1) EP2269071B1 (enExample)
JP (2) JP5882732B2 (enExample)
KR (2) KR101713339B1 (enExample)
CN (1) CN102037362B (enExample)
AU (1) AU2009226152A1 (enExample)
BR (1) BRPI0908737B1 (enExample)
CA (1) CA2718869C (enExample)
DK (1) DK2269071T3 (enExample)
ES (1) ES2527072T3 (enExample)
NZ (1) NZ588587A (enExample)
TW (2) TWI476002B (enExample)
WO (1) WO2009117096A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0908737B1 (pt) 2008-03-19 2022-05-03 Circular Commitment Company Anticorpo, seu uso e método de diagnóstico de carcinoma hepatocelular
AU2009234444A1 (en) * 2008-04-11 2009-10-15 China Synthetic Rubber Corporation Methods, agents and kits for the detection of cancer
ES2732504T3 (es) * 2008-10-29 2019-11-22 Circular Commitment Company Procedimientos y agentes para el diagnóstico y tratamiento del carcinoma hepatocelular
NZ701208A (en) * 2010-06-03 2016-05-27 Genentech Inc Immuno-pet imaging of antibodies and immunoconjugates and uses thereof
JP6163479B2 (ja) 2011-04-14 2017-07-12 エクサレンズ バイオサイエンス リミテッド 肝細胞癌の診断、予後診断、監視および治療方法
KR101463098B1 (ko) * 2011-11-28 2014-11-27 한국생명공학연구원 c-Met에 대한 인간항체에 약물이 접합된 약물 복합체 및 이의 용도
MX357708B (es) 2011-12-14 2018-07-20 Abbvie Deutschland Composicion y metodo para el diagnostico y tratamiento de trastornos relacionados con hierro.
CN104136462B (zh) * 2011-12-14 2017-06-09 艾伯维德国有限责任两合公司 用于诊断和治疗铁相关病症的组合物和方法
CN102796820B (zh) * 2012-08-22 2013-12-04 黄曙 一种原发性肝细胞性肝癌相关的klotho基因单核苷酸多态性其构建方法及其应用
EP2899274A4 (en) * 2012-09-19 2016-06-01 Sysmex Corp METHOD FOR OBTAINING INFORMATION ON HEPATOCELLULAR CARCINOMAS AND MARKERS AND KIT FOR OBTAINING INFORMATION ON HEPATOCELLULAR CARCINOMAS
US9493552B2 (en) * 2013-11-15 2016-11-15 China Synthetic Rubber Corporation Therapeutic biologic for treatment of hepatocellular carcinoma
CN103911440B (zh) * 2014-03-13 2015-04-22 南京医科大学 一种与铂类化疗药物肝脏毒性相关的snp标志物及其应用
EP3366687B1 (en) 2015-09-18 2020-04-29 National University Corporation Tottori University Suppression and regeneration promoting effect of low molecular weight compound on cancer and fibrosis
CN108997497B (zh) * 2018-03-30 2022-02-25 华兰基因工程有限公司 特异结合人质膜膜泡关联蛋白pv-1的单克隆抗体及其制备方法与应用
ES3075793T3 (en) 2020-05-13 2026-08-07 Disc Medicine Inc Anti-hemojuvelin (hjv) antibodies for treating myelofibrosis
AU2021273014A1 (en) 2020-05-13 2022-11-17 AbbVie Deutschland GmbH & Co. KG Anti-hemojuvelin (HJV) antibodies for treating anemia of chronic disease
CN114107449B (zh) * 2020-08-31 2024-04-09 中山大学孙逸仙纪念医院 一种单细胞内原位qPCR方法
CN115925805B (zh) * 2022-07-08 2023-12-22 华兰基因工程(河南)有限公司 一种人质膜膜泡关联蛋白pv-1融合蛋白及其制备方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
US5770429A (en) 1990-08-29 1998-06-23 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
US6749853B1 (en) 1992-03-05 2004-06-15 Board Of Regents, The University Of Texas System Combined methods and compositions for coagulation and tumor treatment
EP0771216B9 (en) 1994-07-11 2003-01-02 The Board Of Regents, The University Of Texas System Methods and compositions for the specific coagulation of tumoral vasculature
US6132729A (en) 1997-01-22 2000-10-17 Board Of Regents, The University Of Texas System Combined tissue factor and chemotherapeutic methods and compositions for coagulation and tumor treatment
US20040067490A1 (en) * 2001-09-07 2004-04-08 Mei Zhong Therapeutic polypeptides, nucleic acids encoding same, and methods of use
US6875570B2 (en) * 2000-09-27 2005-04-05 Curagen Corporation Proteins and nucleic acids encoding same
DE10136273A1 (de) 2001-07-25 2003-02-13 Sabine Debuschewitz Molekulare Marker beim hepatozellulären Karzinom
NZ573739A (en) * 2001-09-18 2010-07-30 Genentech Inc Compositions and methods for the diagnosis and treatment of tumor, particularly colorectal tumor - TAT201
PL1866414T3 (pl) 2005-03-31 2012-10-31 Calando Pharmaceuticals Inc Inhibitory podjednostki 2 reduktazy rybonukleotydowej i ich zastosowania
WO2006110593A2 (en) 2005-04-07 2006-10-19 Macrogenics, Inc. Biological targets for the diagnosis, treatment and prevention of cancer
EP2117591A4 (en) * 2007-01-22 2010-11-17 Mayo Foundation REDUCING TUMOR GROWTH
BRPI0908737B1 (pt) 2008-03-19 2022-05-03 Circular Commitment Company Anticorpo, seu uso e método de diagnóstico de carcinoma hepatocelular
AU2009234444A1 (en) * 2008-04-11 2009-10-15 China Synthetic Rubber Corporation Methods, agents and kits for the detection of cancer
WO2010021822A2 (en) 2008-07-30 2010-02-25 The Regents Of The University Of California Discovery of candidate biomarkers of in vivo apoptosis by global profiling of caspase cleavage sites
ES2732504T3 (es) 2008-10-29 2019-11-22 Circular Commitment Company Procedimientos y agentes para el diagnóstico y tratamiento del carcinoma hepatocelular
WO2011023785A1 (en) 2009-08-27 2011-03-03 Novo Nordisk A/S Targeting tissue factor to activated platelets
US9493552B2 (en) 2013-11-15 2016-11-15 China Synthetic Rubber Corporation Therapeutic biologic for treatment of hepatocellular carcinoma

Similar Documents

Publication Publication Date Title
DK2269071T3 (en) METHOD AND REAGENTS FOR DIAGNOSIS AND TREATMENT OF HEPATOCELLULAR CARCINOM
US10174123B2 (en) Antibody and binding fragment recognizing CACNA2D1 and use thereof
JP2013531655A5 (enExample)
US20140322234A1 (en) Analysis and Targeting of ROR2 in Cancer
JP2024511358A (ja) PDGFRα阻害剤でがんを治療する方法
EP3199553B1 (en) Methods and agents for the diagnosis and treatment of hepatocellular carcinoma
JP2025533015A (ja) 薬物抵抗性肝細胞癌の処置
CA2592330A1 (en) Gitr antibodies for the diagnosis of nsclc
WO2019126594A2 (en) Antibodies to centrin-1, methods of making, and uses thereof
US12319749B2 (en) Antibody and functional fragment thereof
WO2006078780A2 (en) Rdc1 antibodies for the diagnosis of nsclc
HK1241894B (en) Methods and agents for the diagnosis and treatment of hepatocellular carcinoma
HK1152670A (en) Therapeutic use of anti-tweak receptor antibodies
HK1149322B (en) Methods and agents for the diagnosis and treatment of hepatocellular carcinoma
HK1157352B (en) Methods and agents for the diagnosis and treatment of hepatocellular carcinoma
HK1157352A (en) Methods and agents for the diagnosis and treatment of hepatocellular carcinoma