JP2011518773A5 - - Google Patents
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- JP2011518773A5 JP2011518773A5 JP2011500800A JP2011500800A JP2011518773A5 JP 2011518773 A5 JP2011518773 A5 JP 2011518773A5 JP 2011500800 A JP2011500800 A JP 2011500800A JP 2011500800 A JP2011500800 A JP 2011500800A JP 2011518773 A5 JP2011518773 A5 JP 2011518773A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antibody
- subject
- composition
- hcc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6991008P | 2008-03-19 | 2008-03-19 | |
| US61/069,910 | 2008-03-19 | ||
| PCT/US2009/001689 WO2009117096A1 (en) | 2008-03-19 | 2009-03-18 | Methods and agents for the diagnosis and treatment of hepatocellular carcinoma |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014226127A Division JP6073850B2 (ja) | 2008-03-19 | 2014-11-06 | 肝細胞癌の診断および治療のための方法および作用物質 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011518773A JP2011518773A (ja) | 2011-06-30 |
| JP2011518773A5 true JP2011518773A5 (enExample) | 2012-02-23 |
| JP5882732B2 JP5882732B2 (ja) | 2016-03-09 |
Family
ID=40810188
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011500800A Active JP5882732B2 (ja) | 2008-03-19 | 2009-03-18 | 肝細胞癌の診断および治療のための方法および作用物質 |
| JP2014226127A Active JP6073850B2 (ja) | 2008-03-19 | 2014-11-06 | 肝細胞癌の診断および治療のための方法および作用物質 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014226127A Active JP6073850B2 (ja) | 2008-03-19 | 2014-11-06 | 肝細胞癌の診断および治療のための方法および作用物質 |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US8815240B2 (enExample) |
| EP (1) | EP2269071B1 (enExample) |
| JP (2) | JP5882732B2 (enExample) |
| KR (2) | KR101766627B1 (enExample) |
| CN (1) | CN102037362B (enExample) |
| AU (1) | AU2009226152A1 (enExample) |
| BR (1) | BRPI0908737B1 (enExample) |
| CA (1) | CA2718869C (enExample) |
| DK (1) | DK2269071T3 (enExample) |
| ES (1) | ES2527072T3 (enExample) |
| NZ (1) | NZ588587A (enExample) |
| TW (2) | TWI476002B (enExample) |
| WO (1) | WO2009117096A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101766627B1 (ko) | 2008-03-19 | 2017-08-08 | 차이나 신테틱 러버 코포레이션 | 간세포 암종의 진단 및 치료를 위한 방법 및 제제 |
| WO2009126271A1 (en) * | 2008-04-11 | 2009-10-15 | China Synthetic Rubber Corporation | Methods, agents and kits for the detection of cancer |
| ES2631507T3 (es) | 2008-10-29 | 2017-08-31 | China Synthetic Rubber Corporation | Procedimientos y agentes para el diagnóstico y tratamiento del carcinoma hepatocelular |
| NZ701208A (en) * | 2010-06-03 | 2016-05-27 | Genentech Inc | Immuno-pet imaging of antibodies and immunoconjugates and uses thereof |
| WO2012140660A1 (en) | 2011-04-14 | 2012-10-18 | Exalenz Bioscience Ltd. | Methods for diagnosis, prognosis, monitoring and treatment of hepatocellular carcinoma |
| KR101463098B1 (ko) * | 2011-11-28 | 2014-11-27 | 한국생명공학연구원 | ｃ-Ｍｅｔ에 대한 인간항체에 약물이 접합된 약물 복합체 및 이의 용도 |
| CA2855570A1 (en) * | 2011-12-14 | 2013-06-20 | AbbVie Deutschland GmbH & Co. KG | Composition and method for the diagnosis and treatment of iron-related disorders |
| JP6342812B2 (ja) | 2011-12-14 | 2018-06-13 | アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー | 鉄関連障害を診断および治療するための組成物および方法 |
| CN102796820B (zh) * | 2012-08-22 | 2013-12-04 | 黄曙 | 一种原发性肝细胞性肝癌相关的klotho基因单核苷酸多态性其构建方法及其应用 |
| EP2899274A4 (en) * | 2012-09-19 | 2016-06-01 | Sysmex Corp | METHOD FOR OBTAINING INFORMATION ON HEPATOCELLULAR CARCINOMAS AND MARKERS AND KIT FOR OBTAINING INFORMATION ON HEPATOCELLULAR CARCINOMAS |
| US9493552B2 (en) | 2013-11-15 | 2016-11-15 | China Synthetic Rubber Corporation | Therapeutic biologic for treatment of hepatocellular carcinoma |
| CN103911440B (zh) * | 2014-03-13 | 2015-04-22 | 南京医科大学 | 一种与铂类化疗药物肝脏毒性相关的snp标志物及其应用 |
| JP6785487B2 (ja) * | 2015-09-18 | 2020-11-18 | 国立大学法人鳥取大学 | 低分子化合物による癌と線維化の抑制と再生促進の効果 |
| CN108997497B (zh) * | 2018-03-30 | 2022-02-25 | 华兰基因工程有限公司 | 特异结合人质膜膜泡关联蛋白pv-1的单克隆抗体及其制备方法与应用 |
| CA3177830A1 (en) | 2020-05-13 | 2021-11-18 | Maria BECONI | Anti-hemojuvelin (hjv) antibodies for treating myelofibrosis |
| CN114107449B (zh) * | 2020-08-31 | 2024-04-09 | 中山大学孙逸仙纪念医院 | 一种单细胞内原位qPCR方法 |
| CN115925805B (zh) * | 2022-07-08 | 2023-12-22 | 华兰基因工程(河南)有限公司 | 一种人质膜膜泡关联蛋白pv-1融合蛋白及其制备方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5770429A (en) | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US6749853B1 (en) | 1992-03-05 | 2004-06-15 | Board Of Regents, The University Of Texas System | Combined methods and compositions for coagulation and tumor treatment |
| CA2194369C (en) | 1994-07-11 | 2004-08-31 | Philip E. Thorpe | Methods and compositions for the specific coagulation of vasculature |
| IL130908A0 (en) | 1997-01-22 | 2001-01-28 | Univ Texas | Tissue-factor (tf) compositions for coagulation and tumor treatment |
| US20040067490A1 (en) | 2001-09-07 | 2004-04-08 | Mei Zhong | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| US6875570B2 (en) * | 2000-09-27 | 2005-04-05 | Curagen Corporation | Proteins and nucleic acids encoding same |
| DE10136273A1 (de) | 2001-07-25 | 2003-02-13 | Sabine Debuschewitz | Molekulare Marker beim hepatozellulären Karzinom |
| EP2143438B1 (en) * | 2001-09-18 | 2011-07-13 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumors |
| JP2008537551A (ja) | 2005-03-31 | 2008-09-18 | カランド ファーマシューティカルズ， インコーポレイテッド | リボヌクレオチドレダクターゼサブユニット２の阻害剤およびその使用 |
| WO2006110593A2 (en) | 2005-04-07 | 2006-10-19 | Macrogenics, Inc. | Biological targets for the diagnosis, treatment and prevention of cancer |
| EP2117591A4 (en) * | 2007-01-22 | 2010-11-17 | Mayo Foundation | REDUCING TUMOR GROWTH |
| KR101766627B1 (ko) | 2008-03-19 | 2017-08-08 | 차이나 신테틱 러버 코포레이션 | 간세포 암종의 진단 및 치료를 위한 방법 및 제제 |
| WO2009126271A1 (en) | 2008-04-11 | 2009-10-15 | China Synthetic Rubber Corporation | Methods, agents and kits for the detection of cancer |
| WO2010021822A2 (en) | 2008-07-30 | 2010-02-25 | The Regents Of The University Of California | Discovery of candidate biomarkers of in vivo apoptosis by global profiling of caspase cleavage sites |
| ES2631507T3 (es) | 2008-10-29 | 2017-08-31 | China Synthetic Rubber Corporation | Procedimientos y agentes para el diagnóstico y tratamiento del carcinoma hepatocelular |
| WO2011023785A1 (en) | 2009-08-27 | 2011-03-03 | Novo Nordisk A/S | Targeting tissue factor to activated platelets |
| US9493552B2 (en) | 2013-11-15 | 2016-11-15 | China Synthetic Rubber Corporation | Therapeutic biologic for treatment of hepatocellular carcinoma |
-
2009
- 2009-03-18 KR KR1020177005386A patent/KR101766627B1/ko active Active
- 2009-03-18 JP JP2011500800A patent/JP5882732B2/ja active Active
- 2009-03-18 DK DK09723224.3T patent/DK2269071T3/en active
- 2009-03-18 AU AU2009226152A patent/AU2009226152A1/en not_active Abandoned
- 2009-03-18 NZ NZ588587A patent/NZ588587A/xx unknown
- 2009-03-18 CA CA2718869A patent/CA2718869C/en active Active
- 2009-03-18 CN CN200980118081.2A patent/CN102037362B/zh active Active
- 2009-03-18 EP EP09723224.3A patent/EP2269071B1/en active Active
- 2009-03-18 KR KR1020107023301A patent/KR101713339B1/ko active Active
- 2009-03-18 US US12/933,248 patent/US8815240B2/en active Active
- 2009-03-18 BR BRPI0908737-0A patent/BRPI0908737B1/pt active IP Right Grant
- 2009-03-18 ES ES09723224.3T patent/ES2527072T3/es active Active
- 2009-03-18 WO PCT/US2009/001689 patent/WO2009117096A1/en not_active Ceased
- 2009-03-19 TW TW098108921A patent/TWI476002B/zh active
- 2009-03-19 TW TW104103866A patent/TWI566779B/zh active
-
2014
- 2014-07-18 US US14/335,129 patent/US9545443B2/en active Active
- 2014-11-06 JP JP2014226127A patent/JP6073850B2/ja active Active
-
2016
- 2016-12-06 US US15/370,711 patent/US10370445B2/en active Active
-
2019
- 2019-06-24 US US16/450,730 patent/US11339217B2/en active Active
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