JP2011518773A5 - - Google Patents
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- JP2011518773A5 JP2011518773A5 JP2011500800A JP2011500800A JP2011518773A5 JP 2011518773 A5 JP2011518773 A5 JP 2011518773A5 JP 2011500800 A JP2011500800 A JP 2011500800A JP 2011500800 A JP2011500800 A JP 2011500800A JP 2011518773 A5 JP2011518773 A5 JP 2011518773A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antibody
- subject
- composition
- hcc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6991008P | 2008-03-19 | 2008-03-19 | |
| US61/069,910 | 2008-03-19 | ||
| PCT/US2009/001689 WO2009117096A1 (en) | 2008-03-19 | 2009-03-18 | Methods and agents for the diagnosis and treatment of hepatocellular carcinoma |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014226127A Division JP6073850B2 (ja) | 2008-03-19 | 2014-11-06 | 肝細胞癌の診断および治療のための方法および作用物質 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011518773A JP2011518773A (ja) | 2011-06-30 |
| JP2011518773A5 true JP2011518773A5 (enExample) | 2012-02-23 |
| JP5882732B2 JP5882732B2 (ja) | 2016-03-09 |
Family
ID=40810188
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011500800A Active JP5882732B2 (ja) | 2008-03-19 | 2009-03-18 | 肝細胞癌の診断および治療のための方法および作用物質 |
| JP2014226127A Active JP6073850B2 (ja) | 2008-03-19 | 2014-11-06 | 肝細胞癌の診断および治療のための方法および作用物質 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014226127A Active JP6073850B2 (ja) | 2008-03-19 | 2014-11-06 | 肝細胞癌の診断および治療のための方法および作用物質 |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US8815240B2 (enExample) |
| EP (1) | EP2269071B1 (enExample) |
| JP (2) | JP5882732B2 (enExample) |
| KR (2) | KR101766627B1 (enExample) |
| CN (1) | CN102037362B (enExample) |
| AU (1) | AU2009226152A1 (enExample) |
| BR (1) | BRPI0908737B1 (enExample) |
| CA (1) | CA2718869C (enExample) |
| DK (1) | DK2269071T3 (enExample) |
| ES (1) | ES2527072T3 (enExample) |
| NZ (1) | NZ588587A (enExample) |
| TW (2) | TWI566779B (enExample) |
| WO (1) | WO2009117096A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ588587A (en) | 2008-03-19 | 2013-01-25 | China Synthetic Rubber Corp | Methods and agents for the diagnosis and treatment of hepatocellular carcinoma |
| JP2011516077A (ja) * | 2008-04-11 | 2011-05-26 | チャイナ シンセティック ラバー コーポレイション | 癌を検出するための方法、薬剤、およびキット |
| EP3199553B1 (en) * | 2008-10-29 | 2019-04-24 | Circular Commitment Company | Methods and agents for the diagnosis and treatment of hepatocellular carcinoma |
| BR112012029866A2 (pt) * | 2010-06-03 | 2017-03-07 | Genentech Inc | método para a determinação da presença de uma proteína steap-1 |
| WO2012140660A1 (en) | 2011-04-14 | 2012-10-18 | Exalenz Bioscience Ltd. | Methods for diagnosis, prognosis, monitoring and treatment of hepatocellular carcinoma |
| KR101463098B1 (ko) * | 2011-11-28 | 2014-11-27 | 한국생명공학연구원 | ｃ-Ｍｅｔ에 대한 인간항체에 약물이 접합된 약물 복합체 및 이의 용도 |
| CN104144947B (zh) | 2011-12-14 | 2017-10-27 | 艾伯维德国有限责任两合公司 | 用于诊断和治疗铁相关病症的组合物和方法 |
| EP2791175A2 (en) * | 2011-12-14 | 2014-10-22 | Abbvie Deutschland GmbH & Co. KG | Composition and method for the diagnosis and treatment of iron-related disorders |
| CN102796820B (zh) * | 2012-08-22 | 2013-12-04 | 黄曙 | 一种原发性肝细胞性肝癌相关的klotho基因单核苷酸多态性其构建方法及其应用 |
| JP6269492B2 (ja) * | 2012-09-19 | 2018-01-31 | シスメックス株式会社 | 肝細胞癌に関する情報の取得方法、ならびに肝細胞癌に関する情報を取得するためのマーカーおよびキット |
| US9493552B2 (en) * | 2013-11-15 | 2016-11-15 | China Synthetic Rubber Corporation | Therapeutic biologic for treatment of hepatocellular carcinoma |
| CN103911440B (zh) * | 2014-03-13 | 2015-04-22 | 南京医科大学 | 一种与铂类化疗药物肝脏毒性相关的snp标志物及其应用 |
| CN108026104B (zh) * | 2015-09-18 | 2021-06-18 | 国立大学法人鸟取大学 | 利用低分子化合物的癌及纤维化的抑制和再生促进的效果 |
| CN108997497B (zh) * | 2018-03-30 | 2022-02-25 | 华兰基因工程有限公司 | 特异结合人质膜膜泡关联蛋白pv-1的单克隆抗体及其制备方法与应用 |
| KR20230012539A (ko) | 2020-05-13 | 2023-01-26 | 디스크 메디슨, 인크. | 골수섬유증을 치료하기 위한 항-헤모주벨린 (hjv) 항체 |
| CN114107449B (zh) * | 2020-08-31 | 2024-04-09 | 中山大学孙逸仙纪念医院 | 一种单细胞内原位qPCR方法 |
| CN115925805B (zh) * | 2022-07-08 | 2023-12-22 | 华兰基因工程(河南)有限公司 | 一种人质膜膜泡关联蛋白pv-1融合蛋白及其制备方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5770429A (en) | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US6749853B1 (en) | 1992-03-05 | 2004-06-15 | Board Of Regents, The University Of Texas System | Combined methods and compositions for coagulation and tumor treatment |
| EP0771216B9 (en) | 1994-07-11 | 2003-01-02 | The Board Of Regents, The University Of Texas System | Methods and compositions for the specific coagulation of tumoral vasculature |
| ATE244579T1 (de) | 1997-01-22 | 2003-07-15 | Univ Texas | Verfahren und zusammensetzungen des gewebefaktors zur koagulation und behandlung von tumoren |
| US20040067490A1 (en) * | 2001-09-07 | 2004-04-08 | Mei Zhong | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| AU1181802A (en) * | 2000-09-27 | 2002-04-08 | Curagen Corp | Novel proteins and nucleic acids encoding same |
| DE10136273A1 (de) | 2001-07-25 | 2003-02-13 | Sabine Debuschewitz | Molekulare Marker beim hepatozellulären Karzinom |
| ES2431929T3 (es) * | 2001-09-18 | 2013-11-28 | Genentech, Inc. | Composiciones y procedimientos para el diagnóstico y el tratamiento de tumores |
| ATE541928T1 (de) | 2005-03-31 | 2012-02-15 | Calando Pharmaceuticals Inc | Inhibitoren der untereinheit 2 der ribonukleotidreduktase und ihre verwendungen |
| WO2006110593A2 (en) | 2005-04-07 | 2006-10-19 | Macrogenics, Inc. | Biological targets for the diagnosis, treatment and prevention of cancer |
| WO2008091781A1 (en) * | 2007-01-22 | 2008-07-31 | Mayo Foundation For Medical Education And Research | Reducing tumor growth |
| NZ588587A (en) | 2008-03-19 | 2013-01-25 | China Synthetic Rubber Corp | Methods and agents for the diagnosis and treatment of hepatocellular carcinoma |
| JP2011516077A (ja) * | 2008-04-11 | 2011-05-26 | チャイナ シンセティック ラバー コーポレイション | 癌を検出するための方法、薬剤、およびキット |
| WO2010021822A2 (en) | 2008-07-30 | 2010-02-25 | The Regents Of The University Of California | Discovery of candidate biomarkers of in vivo apoptosis by global profiling of caspase cleavage sites |
| EP3199553B1 (en) | 2008-10-29 | 2019-04-24 | Circular Commitment Company | Methods and agents for the diagnosis and treatment of hepatocellular carcinoma |
| JP2013503140A (ja) | 2009-08-27 | 2013-01-31 | ノヴォ ノルディスク アー／エス | 活性化血小板に対する組織因子の標的化 |
| US9493552B2 (en) | 2013-11-15 | 2016-11-15 | China Synthetic Rubber Corporation | Therapeutic biologic for treatment of hepatocellular carcinoma |
-
2009
- 2009-03-18 NZ NZ588587A patent/NZ588587A/xx unknown
- 2009-03-18 BR BRPI0908737-0A patent/BRPI0908737B1/pt active IP Right Grant
- 2009-03-18 US US12/933,248 patent/US8815240B2/en active Active
- 2009-03-18 CA CA2718869A patent/CA2718869C/en active Active
- 2009-03-18 ES ES09723224.3T patent/ES2527072T3/es active Active
- 2009-03-18 WO PCT/US2009/001689 patent/WO2009117096A1/en not_active Ceased
- 2009-03-18 KR KR1020177005386A patent/KR101766627B1/ko active Active
- 2009-03-18 DK DK09723224.3T patent/DK2269071T3/en active
- 2009-03-18 KR KR1020107023301A patent/KR101713339B1/ko active Active
- 2009-03-18 JP JP2011500800A patent/JP5882732B2/ja active Active
- 2009-03-18 EP EP09723224.3A patent/EP2269071B1/en active Active
- 2009-03-18 CN CN200980118081.2A patent/CN102037362B/zh active Active
- 2009-03-18 AU AU2009226152A patent/AU2009226152A1/en not_active Abandoned
- 2009-03-19 TW TW104103866A patent/TWI566779B/zh active
- 2009-03-19 TW TW098108921A patent/TWI476002B/zh active
-
2014
- 2014-07-18 US US14/335,129 patent/US9545443B2/en active Active
- 2014-11-06 JP JP2014226127A patent/JP6073850B2/ja active Active
-
2016
- 2016-12-06 US US15/370,711 patent/US10370445B2/en active Active
-
2019
- 2019-06-24 US US16/450,730 patent/US11339217B2/en active Active
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