JP2005521676A - オピオイドレセプター作動性４−（３−ヒドロキシフェニル）または４−（３−アルコキシフェニル）−１，２，４−トリアゾール化合物 - Google Patents
オピオイドレセプター作動性４−（３−ヒドロキシフェニル）または４−（３−アルコキシフェニル）−１，２，４−トリアゾール化合物 Download PDFInfo
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/14—Nitrogen atoms
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35499002P | 2002-02-07 | 2002-02-07 | |
| PCT/US2003/003746 WO2003066050A1 (en) | 2002-02-07 | 2003-02-07 | Opioid receptor active 4-(3-hydroxyphenyl) or 4-(3-alkoxyphenyl)-1,2,4-triazole compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005521676A true JP2005521676A (ja) | 2005-07-21 |
| JP2005521676A5 JP2005521676A5 (https=) | 2006-02-02 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003565474A Pending JP2005521676A (ja) | 2002-02-07 | 2003-02-07 | オピオイドレセプター作動性４−（３−ヒドロキシフェニル）または４−（３−アルコキシフェニル）−１，２，４−トリアゾール化合物 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US7045520B2 (https=) |
| EP (1) | EP1485088B1 (https=) |
| JP (1) | JP2005521676A (https=) |
| AT (1) | ATE403426T1 (https=) |
| AU (1) | AU2003210916B9 (https=) |
| CA (1) | CA2475767A1 (https=) |
| DE (1) | DE60322680D1 (https=) |
| ES (1) | ES2311711T3 (https=) |
| MX (1) | MXPA04007719A (https=) |
| WO (1) | WO2003066050A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018530749A (ja) * | 2015-08-31 | 2018-10-18 | リージェンツ オブ ザ ユニバーシティ オブ ミネソタ | オピオイド受容体調節因子及びその使用 |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE403426T1 (de) * | 2002-02-07 | 2008-08-15 | Univ Missouri | Opioid-rezeptor-aktive 4-(3-hydroxyphenyl) oder 4-(3-alkoxyphenyl)-1,2,4-triazol-verbindungen |
| WO2006055760A1 (en) * | 2004-11-18 | 2006-05-26 | Synta Pharmaceuticals Corp. | Triazole compounds that modulate hsp90 activity |
| WO2006124687A1 (en) * | 2005-05-12 | 2006-11-23 | University Of Medicine And Dentistry Of New Jersey | Opioid receptor subtype-selective agents |
| WO2008064310A2 (en) * | 2006-11-22 | 2008-05-29 | University Of Medicine And Dentistry Of New Jersey | Mixed opioid receptor active compounds |
| EP2509961B1 (en) | 2009-12-11 | 2016-03-09 | Autifony Therapeutics Limited | Imidazolidinedione derivatives |
| EA023768B1 (ru) | 2010-12-06 | 2016-07-29 | Отифони Терапеутикс Лимитед | ПРОИЗВОДНЫЕ ГИДАНТОИНА, ПОЛЕЗНЫЕ В КАЧЕСТВЕ ИНГИБИТОРОВ Kv3-КАНАЛОВ |
| JP6133790B2 (ja) | 2011-02-18 | 2017-05-24 | ザ スクリプス リサーチ インスティテュート | ミエリン形成細胞運命へのオリゴデンドロサイト前駆細胞の定方向分化 |
| CN103596943B (zh) | 2011-06-07 | 2016-10-12 | 奥蒂福尼疗法有限公司 | 用作kv3抑制剂的乙内酰脲衍生物 |
| EP2757881A4 (en) * | 2011-09-15 | 2014-11-12 | Univ Kansas | KAPPA OPIATE RECEPTOR EFFECTORS AND USES THEREOF |
| EP2613277A1 (en) * | 2012-01-06 | 2013-07-10 | MathPharm GmbH | Method and system for indentifying compounds that bind and preferably activate a target opioid receptor in a pH-dependent manner |
| WO2013134562A1 (en) | 2012-03-09 | 2013-09-12 | Inception 2, Inc. | Triazolone compounds and uses thereof |
| US9669030B2 (en) | 2012-05-22 | 2017-06-06 | Autifony Therapeutics Limited | Hydantoin derivatives as Kv3 inhibitors |
| US9422252B2 (en) | 2012-05-22 | 2016-08-23 | Autifony Therapeutics Limited | Triazoles as Kv3 inhibitors |
| AU2013363398B2 (en) | 2012-12-20 | 2017-06-01 | Tempest Therapeutics, Inc. | Triazolone compounds and uses thereof |
| ES2656012T3 (es) | 2013-02-06 | 2018-02-22 | Bayer Cropscience Aktiengesellschaft | Derivados de pirazol sustituidos con halógeno como pesticidas |
| US9776976B2 (en) | 2013-09-06 | 2017-10-03 | Inception 2, Inc. | Triazolone compounds and uses thereof |
| AU2014375265B2 (en) | 2014-01-03 | 2018-11-01 | Elanco Animal Health Gmbh | Novel pyrazolyl-heteroarylamides as pesticides |
| EP3268353B1 (de) | 2015-03-10 | 2020-09-09 | Bayer Animal Health GmbH | Pyrazolyl-derivate als schädlingsbekämpfungsmittel |
| CN111574368B (zh) * | 2020-05-15 | 2023-03-28 | 西安瑞联新材料股份有限公司 | 一种5-叔丁基-2-羟基苯甲酸甲酯的合成方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2269938A2 (en) * | 1974-05-08 | 1975-12-05 | Delalande Sa | 5-Hydroxymethyl-3,4-diphenyl-1,2,4-triazoles - with anticholinergic, bronchodilator, antidepressant, analgesic, vasodilator activity, etc. |
| FR2488891A1 (fr) | 1980-08-22 | 1982-02-26 | Roussel Uclaf | Nouveaux derives du 4h-1,2,4-triazole, leur procede de preparation et leur application comme medicament |
| US4481360A (en) * | 1983-08-26 | 1984-11-06 | The Upjohn Company | 4H-1,2,4-Triazol-3-yl compounds |
| US5310724A (en) * | 1990-02-09 | 1994-05-10 | Fmc Corporation | Herbicidal substituted phenyl-1,2,4-triazol-5(1H)-thiones |
| US5108486A (en) * | 1990-02-09 | 1992-04-28 | Kanagawa Chemical Laboratory, Ltd. | Herbicidal substituted-phenyl-1,2,4-triazol-5(1H)-thiones and -ones |
| AU9297798A (en) * | 1997-09-16 | 1999-04-05 | G.D. Searle & Co. | Substituted 1,2,4-triazoles useful for inhibiting cholesteryl ester transfer protein activity |
| JP2000063363A (ja) | 1998-08-12 | 2000-02-29 | Yamanouchi Pharmaceut Co Ltd | 新規なトリアゾール誘導体 |
| HN1999000149A (es) * | 1998-09-09 | 2000-01-12 | Pfizer Prod Inc | Derivados de 4,4-biarilpiperidina |
| ATE403426T1 (de) * | 2002-02-07 | 2008-08-15 | Univ Missouri | Opioid-rezeptor-aktive 4-(3-hydroxyphenyl) oder 4-(3-alkoxyphenyl)-1,2,4-triazol-verbindungen |
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- 2003-02-07 AT AT03737705T patent/ATE403426T1/de not_active IP Right Cessation
- 2003-02-07 CA CA002475767A patent/CA2475767A1/en not_active Abandoned
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2006
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2007
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018530749A (ja) * | 2015-08-31 | 2018-10-18 | リージェンツ オブ ザ ユニバーシティ オブ ミネソタ | オピオイド受容体調節因子及びその使用 |
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| US7776898B2 (en) | 2010-08-17 |
| AU2003210916B2 (en) | 2008-10-23 |
| ATE403426T1 (de) | 2008-08-15 |
| MXPA04007719A (es) | 2005-09-08 |
| US20080070964A1 (en) | 2008-03-20 |
| US7045520B2 (en) | 2006-05-16 |
| DE60322680D1 (de) | 2008-09-18 |
| AU2003210916B9 (en) | 2008-12-18 |
| EP1485088A1 (en) | 2004-12-15 |
| US20060128776A1 (en) | 2006-06-15 |
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| US20030225072A1 (en) | 2003-12-04 |
| ES2311711T3 (es) | 2009-02-16 |
| US7294720B2 (en) | 2007-11-13 |
| CA2475767A1 (en) | 2003-08-14 |
| AU2003210916A1 (en) | 2003-09-02 |
| WO2003066050A1 (en) | 2003-08-14 |
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