FR2269938A2 - 5-Hydroxymethyl-3,4-diphenyl-1,2,4-triazoles - with anticholinergic, bronchodilator, antidepressant, analgesic, vasodilator activity, etc. - Google Patents
5-Hydroxymethyl-3,4-diphenyl-1,2,4-triazoles - with anticholinergic, bronchodilator, antidepressant, analgesic, vasodilator activity, etc.Info
- Publication number
- FR2269938A2 FR2269938A2 FR7415855A FR7415855A FR2269938A2 FR 2269938 A2 FR2269938 A2 FR 2269938A2 FR 7415855 A FR7415855 A FR 7415855A FR 7415855 A FR7415855 A FR 7415855A FR 2269938 A2 FR2269938 A2 FR 2269938A2
- Authority
- FR
- France
- Prior art keywords
- hydroxymethyl
- diphenyl
- bronchodilator
- anticholinergic
- antidepressant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
5-Hydroxymethyl-3,4-diphenyl-1,2,4-triazines of formula (I): (where X is halo, 1-4C alkyl, CF3, OH, 1-3C alkoxy, benzyloxy, EtO2C-, or -CO2H; n is 1, 2 or 3), are used for treatment of asthma, intestinal spasm, peptic ulcer, depression, inflammatory pain, pain of miscellaneous origins, cardiac insufficiency, oedema, hypertension or hypotension.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7415855A FR2269938A2 (en) | 1974-05-08 | 1974-05-08 | 5-Hydroxymethyl-3,4-diphenyl-1,2,4-triazoles - with anticholinergic, bronchodilator, antidepressant, analgesic, vasodilator activity, etc. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7415855A FR2269938A2 (en) | 1974-05-08 | 1974-05-08 | 5-Hydroxymethyl-3,4-diphenyl-1,2,4-triazoles - with anticholinergic, bronchodilator, antidepressant, analgesic, vasodilator activity, etc. |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2269938A2 true FR2269938A2 (en) | 1975-12-05 |
FR2269938B2 FR2269938B2 (en) | 1978-02-03 |
Family
ID=9138579
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7415855A Granted FR2269938A2 (en) | 1974-05-08 | 1974-05-08 | 5-Hydroxymethyl-3,4-diphenyl-1,2,4-triazoles - with anticholinergic, bronchodilator, antidepressant, analgesic, vasodilator activity, etc. |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2269938A2 (en) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3133185A1 (en) * | 1980-08-22 | 1982-04-08 | Roussel-Uclaf, 75007 Paris | "4H-1,2,4-TRIAZOLE DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF" |
FR2570699A1 (en) * | 1984-09-24 | 1986-03-28 | Roussel Uclaf | NOVEL PROCESS FOR THE PREPARATION OF 4H-1,2,4-TRIAZOLE DERIVATIVES, NOVEL TRIAZOLES THUS OBTAINED, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THEM |
EP0335381A1 (en) * | 1988-03-30 | 1989-10-04 | Boehringer Ingelheim Kg | 2,3,4-Substituted imidazoles and 3,4,5-substituted 1,2,4-triazoles, their preparation and their use |
EP0335144A1 (en) * | 1988-03-12 | 1989-10-04 | Boehringer Ingelheim Kg | 3,4,5-Substituted-4H-1,2,4-triazoles, their preparation and their use |
WO1991002731A1 (en) * | 1989-08-19 | 1991-03-07 | Boehringer Ingelheim Kg | Substituted n-heterocycles, their preparation and their use |
WO2003066050A1 (en) * | 2002-02-07 | 2003-08-14 | The Curators Of The University Of Missouri | Opioid receptor active 4-(3-hydroxyphenyl) or 4-(3-alkoxyphenyl)-1,2,4-triazole compounds |
-
1974
- 1974-05-08 FR FR7415855A patent/FR2269938A2/en active Granted
Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3133185A1 (en) * | 1980-08-22 | 1982-04-08 | Roussel-Uclaf, 75007 Paris | "4H-1,2,4-TRIAZOLE DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF" |
FR2570699A1 (en) * | 1984-09-24 | 1986-03-28 | Roussel Uclaf | NOVEL PROCESS FOR THE PREPARATION OF 4H-1,2,4-TRIAZOLE DERIVATIVES, NOVEL TRIAZOLES THUS OBTAINED, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THEM |
EP0176444A1 (en) * | 1984-09-24 | 1986-04-02 | Roussel-Uclaf | Process for the preparation of derivatives of 4H-1,2,4-triazole, triazoles so obtained, their use as medicaments, and pharmaceutical compositons containing them |
EP0335144A1 (en) * | 1988-03-12 | 1989-10-04 | Boehringer Ingelheim Kg | 3,4,5-Substituted-4H-1,2,4-triazoles, their preparation and their use |
FR2629457A1 (en) * | 1988-03-30 | 1989-10-06 | Boehringer Ingelheim Kg | IMIDAZOLES SUBSTITUTED IN POSITIONS 2, 3, 4, AND 1, 2, 4-TRIAZOLES SUBSTITUTED IN POSITIONS 3, 4, 5, THEIR PREPARATION AND THEIR USE |
WO1989009212A1 (en) * | 1988-03-30 | 1989-10-05 | Boehringer Ingelheim Kg | New 2,3,4-substituted imidazols and 3,4,5-substituted 1,2,4-triazols, preparation and use thereof |
EP0335381A1 (en) * | 1988-03-30 | 1989-10-04 | Boehringer Ingelheim Kg | 2,3,4-Substituted imidazoles and 3,4,5-substituted 1,2,4-triazoles, their preparation and their use |
WO1991002731A1 (en) * | 1989-08-19 | 1991-03-07 | Boehringer Ingelheim Kg | Substituted n-heterocycles, their preparation and their use |
GR900100619A (en) * | 1989-08-19 | 1991-12-30 | Boehringer Ingelheim Kg | Substituted n-heterocyclic preparation process and use thereof |
WO2003066050A1 (en) * | 2002-02-07 | 2003-08-14 | The Curators Of The University Of Missouri | Opioid receptor active 4-(3-hydroxyphenyl) or 4-(3-alkoxyphenyl)-1,2,4-triazole compounds |
US7045520B2 (en) | 2002-02-07 | 2006-05-16 | The Curators Of The University Of Missouri | Opioid receptor active compounds |
US7294720B2 (en) | 2002-02-07 | 2007-11-13 | The Curators Of The University Of Missouri | Opioid receptor active compounds |
US7776898B2 (en) | 2002-02-07 | 2010-08-17 | The Curators Of The University Of Missouri | Opioid receptor active compounds |
Also Published As
Publication number | Publication date |
---|---|
FR2269938B2 (en) | 1978-02-03 |
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