FR2269938A2 - 5-Hydroxymethyl-3,4-diphenyl-1,2,4-triazoles - with anticholinergic, bronchodilator, antidepressant, analgesic, vasodilator activity, etc. - Google Patents

5-Hydroxymethyl-3,4-diphenyl-1,2,4-triazoles - with anticholinergic, bronchodilator, antidepressant, analgesic, vasodilator activity, etc.

Info

Publication number
FR2269938A2
FR2269938A2 FR7415855A FR7415855A FR2269938A2 FR 2269938 A2 FR2269938 A2 FR 2269938A2 FR 7415855 A FR7415855 A FR 7415855A FR 7415855 A FR7415855 A FR 7415855A FR 2269938 A2 FR2269938 A2 FR 2269938A2
Authority
FR
France
Prior art keywords
hydroxymethyl
diphenyl
bronchodilator
anticholinergic
antidepressant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7415855A
Other languages
French (fr)
Other versions
FR2269938B2 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande SA filed Critical Delalande SA
Priority to FR7415855A priority Critical patent/FR2269938A2/en
Publication of FR2269938A2 publication Critical patent/FR2269938A2/en
Application granted granted Critical
Publication of FR2269938B2 publication Critical patent/FR2269938B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

5-Hydroxymethyl-3,4-diphenyl-1,2,4-triazines of formula (I): (where X is halo, 1-4C alkyl, CF3, OH, 1-3C alkoxy, benzyloxy, EtO2C-, or -CO2H; n is 1, 2 or 3), are used for treatment of asthma, intestinal spasm, peptic ulcer, depression, inflammatory pain, pain of miscellaneous origins, cardiac insufficiency, oedema, hypertension or hypotension.
FR7415855A 1974-05-08 1974-05-08 5-Hydroxymethyl-3,4-diphenyl-1,2,4-triazoles - with anticholinergic, bronchodilator, antidepressant, analgesic, vasodilator activity, etc. Granted FR2269938A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7415855A FR2269938A2 (en) 1974-05-08 1974-05-08 5-Hydroxymethyl-3,4-diphenyl-1,2,4-triazoles - with anticholinergic, bronchodilator, antidepressant, analgesic, vasodilator activity, etc.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7415855A FR2269938A2 (en) 1974-05-08 1974-05-08 5-Hydroxymethyl-3,4-diphenyl-1,2,4-triazoles - with anticholinergic, bronchodilator, antidepressant, analgesic, vasodilator activity, etc.

Publications (2)

Publication Number Publication Date
FR2269938A2 true FR2269938A2 (en) 1975-12-05
FR2269938B2 FR2269938B2 (en) 1978-02-03

Family

ID=9138579

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7415855A Granted FR2269938A2 (en) 1974-05-08 1974-05-08 5-Hydroxymethyl-3,4-diphenyl-1,2,4-triazoles - with anticholinergic, bronchodilator, antidepressant, analgesic, vasodilator activity, etc.

Country Status (1)

Country Link
FR (1) FR2269938A2 (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3133185A1 (en) * 1980-08-22 1982-04-08 Roussel-Uclaf, 75007 Paris "4H-1,2,4-TRIAZOLE DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF"
FR2570699A1 (en) * 1984-09-24 1986-03-28 Roussel Uclaf NOVEL PROCESS FOR THE PREPARATION OF 4H-1,2,4-TRIAZOLE DERIVATIVES, NOVEL TRIAZOLES THUS OBTAINED, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THEM
EP0335381A1 (en) * 1988-03-30 1989-10-04 Boehringer Ingelheim Kg 2,3,4-Substituted imidazoles and 3,4,5-substituted 1,2,4-triazoles, their preparation and their use
EP0335144A1 (en) * 1988-03-12 1989-10-04 Boehringer Ingelheim Kg 3,4,5-Substituted-4H-1,2,4-triazoles, their preparation and their use
WO1991002731A1 (en) * 1989-08-19 1991-03-07 Boehringer Ingelheim Kg Substituted n-heterocycles, their preparation and their use
WO2003066050A1 (en) * 2002-02-07 2003-08-14 The Curators Of The University Of Missouri Opioid receptor active 4-(3-hydroxyphenyl) or 4-(3-alkoxyphenyl)-1,2,4-triazole compounds

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3133185A1 (en) * 1980-08-22 1982-04-08 Roussel-Uclaf, 75007 Paris "4H-1,2,4-TRIAZOLE DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF"
FR2570699A1 (en) * 1984-09-24 1986-03-28 Roussel Uclaf NOVEL PROCESS FOR THE PREPARATION OF 4H-1,2,4-TRIAZOLE DERIVATIVES, NOVEL TRIAZOLES THUS OBTAINED, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THEM
EP0176444A1 (en) * 1984-09-24 1986-04-02 Roussel-Uclaf Process for the preparation of derivatives of 4H-1,2,4-triazole, triazoles so obtained, their use as medicaments, and pharmaceutical compositons containing them
EP0335144A1 (en) * 1988-03-12 1989-10-04 Boehringer Ingelheim Kg 3,4,5-Substituted-4H-1,2,4-triazoles, their preparation and their use
FR2629457A1 (en) * 1988-03-30 1989-10-06 Boehringer Ingelheim Kg IMIDAZOLES SUBSTITUTED IN POSITIONS 2, 3, 4, AND 1, 2, 4-TRIAZOLES SUBSTITUTED IN POSITIONS 3, 4, 5, THEIR PREPARATION AND THEIR USE
WO1989009212A1 (en) * 1988-03-30 1989-10-05 Boehringer Ingelheim Kg New 2,3,4-substituted imidazols and 3,4,5-substituted 1,2,4-triazols, preparation and use thereof
EP0335381A1 (en) * 1988-03-30 1989-10-04 Boehringer Ingelheim Kg 2,3,4-Substituted imidazoles and 3,4,5-substituted 1,2,4-triazoles, their preparation and their use
WO1991002731A1 (en) * 1989-08-19 1991-03-07 Boehringer Ingelheim Kg Substituted n-heterocycles, their preparation and their use
GR900100619A (en) * 1989-08-19 1991-12-30 Boehringer Ingelheim Kg Substituted n-heterocyclic preparation process and use thereof
WO2003066050A1 (en) * 2002-02-07 2003-08-14 The Curators Of The University Of Missouri Opioid receptor active 4-(3-hydroxyphenyl) or 4-(3-alkoxyphenyl)-1,2,4-triazole compounds
US7045520B2 (en) 2002-02-07 2006-05-16 The Curators Of The University Of Missouri Opioid receptor active compounds
US7294720B2 (en) 2002-02-07 2007-11-13 The Curators Of The University Of Missouri Opioid receptor active compounds
US7776898B2 (en) 2002-02-07 2010-08-17 The Curators Of The University Of Missouri Opioid receptor active compounds

Also Published As

Publication number Publication date
FR2269938B2 (en) 1978-02-03

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