JP2005521637A5 - - Google Patents
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- Publication number
- JP2005521637A5 JP2005521637A5 JP2003539697A JP2003539697A JP2005521637A5 JP 2005521637 A5 JP2005521637 A5 JP 2005521637A5 JP 2003539697 A JP2003539697 A JP 2003539697A JP 2003539697 A JP2003539697 A JP 2003539697A JP 2005521637 A5 JP2005521637 A5 JP 2005521637A5
- Authority
- JP
- Japan
- Prior art keywords
- patient
- compound
- plasma cortisol
- suppression
- estradi
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229960000890 hydrocortisone Drugs 0.000 claims 2
- 230000001629 suppression Effects 0.000 claims 2
- -1 1,3-benzodioxol-5-yl Chemical group 0.000 claims 1
- 125000000530 1-propynyl group Chemical group [H]C([H])([H])C#C* 0.000 claims 1
- 229960003957 dexamethasone Drugs 0.000 claims 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 208000024714 major depressive disease Diseases 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01204072 | 2001-10-26 | ||
| PCT/EP2002/011732 WO2003037354A1 (en) | 2001-10-26 | 2002-10-21 | USE OF (11β, 17β)-11-(1,3-BENZODIOXOL-5-YL)-17-HYDROXY-17-(1-PROPYNYL)-ESTRA-4,9-DIEN-3-ONE IN THE TREATMENT OF MAJOR DEPRESSIVE DISORDER |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005521637A JP2005521637A (ja) | 2005-07-21 |
| JP2005521637A5 true JP2005521637A5 (enExample) | 2006-01-05 |
| JP4647909B2 JP4647909B2 (ja) | 2011-03-09 |
Family
ID=8181136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003539697A Expired - Fee Related JP4647909B2 (ja) | 2001-10-26 | 2002-10-21 | 大うつ病性障害の治療における（１１β，１７β）−１１−（１，３−ベンゾジオキソール−５−イル）−１７−ヒドロキシ−１７−（１−プロピニル）エストラ−４，９−ジエン−３−オンの使用 |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US20040266863A1 (enExample) |
| EP (2) | EP1441739B1 (enExample) |
| JP (1) | JP4647909B2 (enExample) |
| KR (1) | KR20050038580A (enExample) |
| CN (1) | CN100531738C (enExample) |
| AT (2) | ATE317700T1 (enExample) |
| AU (1) | AU2002348996B2 (enExample) |
| BR (1) | BR0213466A (enExample) |
| CA (1) | CA2463446C (enExample) |
| CY (1) | CY1110173T1 (enExample) |
| DE (2) | DE60209248D1 (enExample) |
| DK (1) | DK1652526T3 (enExample) |
| EC (1) | ECSP045080A (enExample) |
| ES (1) | ES2319563T3 (enExample) |
| HR (1) | HRP20040370B1 (enExample) |
| HU (1) | HUP0500070A3 (enExample) |
| IL (2) | IL161248A0 (enExample) |
| IS (1) | IS2702B (enExample) |
| MX (1) | MXPA04003781A (enExample) |
| NO (1) | NO332978B1 (enExample) |
| NZ (1) | NZ532429A (enExample) |
| PL (1) | PL206687B1 (enExample) |
| PT (1) | PT1652526E (enExample) |
| RU (1) | RU2302245C2 (enExample) |
| WO (1) | WO2003037354A1 (enExample) |
| ZA (1) | ZA200403088B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050080061A1 (en) * | 2003-07-23 | 2005-04-14 | Corcept Therapeutics, Inc. | Antiglucocorticoid therapy for the prevention of neurological damage in premature infants |
| AU2011236053B2 (en) * | 2004-11-19 | 2014-06-26 | Merck Sharpe & Dohme B.V. | Drug combination comprising a selective serotonin reuptake inhibitor and a glucocorticoid receptor antagonist for the treatment of depression |
| EP2292269A3 (en) * | 2004-11-19 | 2011-08-10 | N.V. Organon | Drug combination comprising a selective serotonin reuptake inhibitor and a glucocorticoid receptor antagonist for the treatment of depression |
| CA2649894A1 (en) * | 2006-05-02 | 2007-11-15 | Corcept Therapeutics, Inc. | The use of a glucocorticoid receptor ii antagonist to treat depression in patients taking il-2 |
| WO2012106514A2 (en) * | 2011-02-03 | 2012-08-09 | Pop Test Cortisol Llc | System and method for diagnosis and treatment |
| EP2699245A4 (en) * | 2011-04-18 | 2014-12-10 | Pop Test Cortisol Llc | TREATMENT AGAINST HAIR LOSS |
| US8986677B2 (en) * | 2012-07-30 | 2015-03-24 | Pop Test Cortisol Llc | Therapeutic compositions and methods |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4814333A (en) * | 1987-07-28 | 1989-03-21 | The Trustees Of Dartmouth College | Method for treatment of hypercortisolemic, depressed patients |
| DE4447401A1 (de) * | 1994-12-23 | 1996-07-04 | Schering Ag | 14,17-C¶2¶-überbrückte Steroide |
| IL118974A (en) * | 1995-08-17 | 2001-09-13 | Akzo Nobel Nv | History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them |
| DE19727772A1 (de) * | 1997-06-30 | 1999-01-28 | Forschungszentrum Juelich Gmbh | Magnetflußsensor mit ringförmiger Sonde |
| CN1528315A (zh) * | 1997-10-06 | 2004-09-15 | ������˹̹�������ѧ�й�ίԱ�� | 治疗糖皮质素功能失调相关性精神病的方法 |
| CN1556709A (zh) * | 2001-03-23 | 2004-12-22 | �Ƹ��� | 使用糖皮质激素受体特效拮抗剂治疗压力症的方法 |
| IL158744A0 (en) * | 2001-05-04 | 2004-05-12 | Corcept Therapeutics Inc | Methods for treating delirium using glucocorticoid receptor-specific antagonists |
| MXPA04001893A (es) * | 2001-08-31 | 2005-03-07 | Corcept Therapeutics Inc | Metodos para inhibir deterioro cognoscitivo en adultos con sindrome de down. |
-
2002
- 2002-10-21 CA CA2463446A patent/CA2463446C/en not_active Expired - Fee Related
- 2002-10-21 JP JP2003539697A patent/JP4647909B2/ja not_active Expired - Fee Related
- 2002-10-21 CN CNB028210417A patent/CN100531738C/zh not_active Expired - Fee Related
- 2002-10-21 EP EP02781273A patent/EP1441739B1/en not_active Expired - Lifetime
- 2002-10-21 WO PCT/EP2002/011732 patent/WO2003037354A1/en not_active Ceased
- 2002-10-21 AT AT02781273T patent/ATE317700T1/de active
- 2002-10-21 HU HU0500070A patent/HUP0500070A3/hu unknown
- 2002-10-21 AT AT06101005T patent/ATE420649T1/de active
- 2002-10-21 PT PT06101005T patent/PT1652526E/pt unknown
- 2002-10-21 DE DE60209248T patent/DE60209248D1/de not_active Expired - Lifetime
- 2002-10-21 BR BR0213466-7A patent/BR0213466A/pt not_active IP Right Cessation
- 2002-10-21 EP EP06101005A patent/EP1652526B1/en not_active Expired - Lifetime
- 2002-10-21 DE DE60230936T patent/DE60230936D1/de not_active Expired - Lifetime
- 2002-10-21 NZ NZ532429A patent/NZ532429A/en not_active IP Right Cessation
- 2002-10-21 RU RU2004116082/15A patent/RU2302245C2/ru not_active IP Right Cessation
- 2002-10-21 US US10/493,981 patent/US20040266863A1/en not_active Abandoned
- 2002-10-21 MX MXPA04003781A patent/MXPA04003781A/es active IP Right Grant
- 2002-10-21 HR HRP20040370AA patent/HRP20040370B1/xx not_active IP Right Cessation
- 2002-10-21 ES ES06101005T patent/ES2319563T3/es not_active Expired - Lifetime
- 2002-10-21 KR KR1020047006050A patent/KR20050038580A/ko not_active Ceased
- 2002-10-21 IL IL16124802A patent/IL161248A0/xx unknown
- 2002-10-21 PL PL369261A patent/PL206687B1/pl not_active IP Right Cessation
- 2002-10-21 AU AU2002348996A patent/AU2002348996B2/en not_active Ceased
- 2002-10-21 DK DK06101005T patent/DK1652526T3/da active
-
2004
- 2004-03-31 IS IS7204A patent/IS2702B/is unknown
- 2004-04-01 IL IL161248A patent/IL161248A/en not_active IP Right Cessation
- 2004-04-22 ZA ZA200403088A patent/ZA200403088B/en unknown
- 2004-04-23 EC EC2004005080A patent/ECSP045080A/es unknown
- 2004-04-23 NO NO20041651A patent/NO332978B1/no not_active IP Right Cessation
-
2009
- 2009-02-02 CY CY20091100116T patent/CY1110173T1/el unknown
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