JP2005520566A - Cripto特異的抗体 - Google Patents

Cripto特異的抗体 Download PDF

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Publication number
JP2005520566A
JP2005520566A JP2003580477A JP2003580477A JP2005520566A JP 2005520566 A JP2005520566 A JP 2005520566A JP 2003580477 A JP2003580477 A JP 2003580477A JP 2003580477 A JP2003580477 A JP 2003580477A JP 2005520566 A JP2005520566 A JP 2005520566A
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JP
Japan
Prior art keywords
antibody
cripto
tumor
antibodies
group
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Pending
Application number
JP2003580477A
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English (en)
Japanese (ja)
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JP2005520566A5 (enExample
Inventor
ミチェル サニコラ−ナデル,
アドキンス,ヒーザー
スティーブン ドナルド ミクラス,
ポウル レイホーン,
スーザン ゲイル シファー,
ケビン ピー. ウィリアム,
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biogen Inc
Biogen MA Inc
Original Assignee
Biogen Inc
Biogen Idec Inc
Biogen Idec MA Inc
Biogen MA Inc
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Priority claimed from PCT/US2002/011950 external-priority patent/WO2002088170A2/en
Application filed by Biogen Inc, Biogen Idec Inc, Biogen Idec MA Inc, Biogen MA Inc filed Critical Biogen Inc
Publication of JP2005520566A publication Critical patent/JP2005520566A/ja
Publication of JP2005520566A5 publication Critical patent/JP2005520566A5/ja
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2003580477A 2002-03-22 2002-10-01 Cripto特異的抗体 Pending JP2005520566A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36700202P 2002-03-22 2002-03-22
PCT/US2002/011950 WO2002088170A2 (en) 2001-04-26 2002-04-17 Cripto blocking antibodies and uses thereof
PCT/US2002/031462 WO2003083041A2 (en) 2002-03-22 2002-10-01 Cripto-specific antibodies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009020949A Division JP2009161539A (ja) 2002-03-22 2009-01-30 Cripto特異的抗体

Publications (2)

Publication Number Publication Date
JP2005520566A true JP2005520566A (ja) 2005-07-14
JP2005520566A5 JP2005520566A5 (enExample) 2006-01-12

Family

ID=29586137

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003580477A Pending JP2005520566A (ja) 2002-03-22 2002-10-01 Cripto特異的抗体

Country Status (4)

Country Link
EP (1) EP1494693B1 (enExample)
JP (1) JP2005520566A (enExample)
AU (1) AU2002334799B2 (enExample)
WO (1) WO2003083041A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011522224A (ja) * 2008-04-21 2011-07-28 メルク・シャープ・エンド・ドーム・コーポレイション 膵ベータ細胞質量生物マーカー
JP2014223079A (ja) * 2007-07-13 2014-12-04 バク アイピー ベスローテン フェンノートシャップ 哺乳動物IgGと結合する単一ドメイン抗原結合タンパク質

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014223079A (ja) * 2007-07-13 2014-12-04 バク アイピー ベスローテン フェンノートシャップ 哺乳動物IgGと結合する単一ドメイン抗原結合タンパク質
US10259886B2 (en) 2007-07-13 2019-04-16 Bac Ip B.V. Single-domain antigen-binding proteins that bind mammalian IgG
JP2011522224A (ja) * 2008-04-21 2011-07-28 メルク・シャープ・エンド・ドーム・コーポレイション 膵ベータ細胞質量生物マーカー

Also Published As

Publication number Publication date
WO2003083041A2 (en) 2003-10-09
WO2003083041A3 (en) 2003-12-04
WO2003083041A8 (en) 2004-09-16
AU2002334799B2 (en) 2009-05-07
EP1494693A4 (en) 2006-08-02
EP1494693B1 (en) 2010-12-08
AU2002334799A1 (en) 2003-10-13
EP1494693A2 (en) 2005-01-12

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