AU2002334799B2 - Cripto-specific antibodies - Google Patents
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- AU2002334799B2 AU2002334799B2 AU2002334799A AU2002334799A AU2002334799B2 AU 2002334799 B2 AU2002334799 B2 AU 2002334799B2 AU 2002334799 A AU2002334799 A AU 2002334799A AU 2002334799 A AU2002334799 A AU 2002334799A AU 2002334799 B2 AU2002334799 B2 AU 2002334799B2
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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Applications Claiming Priority (8)
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| US60/286,782 | 2001-04-26 | ||
| US60/293,020 | 2001-05-17 | ||
| US60/301,091 | 2001-06-26 | ||
| US36700202P | 2002-03-22 | 2002-03-22 | |
| US60/367,002 | 2002-03-22 | ||
| AUPCT/US2002/011950 | 2002-04-17 | ||
| PCT/US2002/011950 WO2002088170A2 (en) | 2001-04-26 | 2002-04-17 | Cripto blocking antibodies and uses thereof |
| PCT/US2002/031462 WO2003083041A2 (en) | 2002-03-22 | 2002-10-01 | Cripto-specific antibodies |
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| AU2002303364A Division AU2002303364A1 (en) | 2001-04-26 | 2002-04-17 | Cripto blocking antibodies and uses thereof |
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| AU2002334799A1 AU2002334799A1 (en) | 2003-10-13 |
| AU2002334799B2 true AU2002334799B2 (en) | 2009-05-07 |
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| EP (1) | EP1494693B1 (enExample) |
| JP (1) | JP2005520566A (enExample) |
| AU (1) | AU2002334799B2 (enExample) |
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| US7582299B2 (en) | 2001-04-26 | 2009-09-01 | Biogen Idec Ma Inc. | Cripto-specific antibodies |
| SK14432003A3 (sk) * | 2001-04-26 | 2004-07-07 | Biogen, Inc. | Protilátka špecifická pre Cripto, kompozícia obsahujúca takúto protilátku a jej použitie |
| WO2005000898A2 (en) | 2003-06-27 | 2005-01-06 | Biogen Idec Ma Inc. | Use of hydrophobic-interaction-chromatography or hinge-region modifications for the production of homogeneous antibody-solutions |
| CA2539116C (en) | 2003-09-15 | 2014-11-18 | Research Development Foundation | Cripto antagonism of activin and tgf-b signaling |
| NZ583292A (en) | 2003-11-06 | 2012-03-30 | Seattle Genetics Inc | Monomethylvaline compounds capable of conjugation to ligands |
| CA2545603A1 (en) | 2003-11-12 | 2005-05-26 | Biogen Idec Ma Inc. | Neonatal fc receptor (fcrn)-binding polypeptide variants, dimeric fc binding proteins and methods related thereto |
| MXPA06014065A (es) | 2004-06-01 | 2007-01-31 | Genentech Inc | Conjugados de droga-anticuerpo y metodos. |
| ES2579805T3 (es) | 2004-09-23 | 2016-08-16 | Genentech, Inc. | Anticuerpos y conjugados modificados por ingeniería genética con cisteína |
| US20100111856A1 (en) | 2004-09-23 | 2010-05-06 | Herman Gill | Zirconium-radiolabeled, cysteine engineered antibody conjugates |
| EP2311880A3 (en) | 2005-01-05 | 2011-07-27 | Biogen Idec MA Inc. | Cripto binding molecules |
| US20100041032A1 (en) * | 2006-04-28 | 2010-02-18 | Biogen Idec Ma Inc. | Composition and methods for the detection of cripto-3 |
| EP2162152A2 (en) * | 2007-06-01 | 2010-03-17 | Biogen Idec MA, Inc. | Cripto binding molecules |
| EP2170960B1 (en) | 2007-07-13 | 2015-07-29 | Bac Ip B.V. | Single-domain antigen-binding proteins that bind mammalian igg |
| JP2011522224A (ja) * | 2008-04-21 | 2011-07-28 | メルク・シャープ・エンド・ドーム・コーポレイション | 膵ベータ細胞質量生物マーカー |
| CA2809819A1 (en) | 2009-09-09 | 2011-03-17 | Centrose, Llc | Extracellular targeted drug conjugates |
| US20110256157A1 (en) | 2010-04-15 | 2011-10-20 | Spirogen Limited | Pyrrolobenzodiazepines and conjugates thereof |
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| ES2544608T3 (es) | 2010-11-17 | 2015-09-02 | Genentech, Inc. | Conjugados de anticuerpo y de alaninil-maitansinol |
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| US5793616A (en) * | 1997-03-31 | 1998-08-11 | Compaq Computer Corp. | Computer system with special circuit board arrangement |
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| US5256643A (en) * | 1990-05-29 | 1993-10-26 | The Government Of The United States | Human cripto protein |
| US5264557A (en) * | 1991-08-23 | 1993-11-23 | The United States Of America As Represented By The Department Of Health And Human Services | Polypeptide of a human cripto-related gene, CR-3 |
| GB0020953D0 (en) * | 2000-08-24 | 2000-10-11 | Smithkline Beecham Biolog | Vaccine |
| SK14432003A3 (sk) * | 2001-04-26 | 2004-07-07 | Biogen, Inc. | Protilátka špecifická pre Cripto, kompozícia obsahujúca takúto protilátku a jej použitie |
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- 2002-10-01 WO PCT/US2002/031462 patent/WO2003083041A2/en not_active Ceased
- 2002-10-01 EP EP02807155A patent/EP1494693B1/en not_active Expired - Lifetime
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5793616A (en) * | 1997-03-31 | 1998-08-11 | Compaq Computer Corp. | Computer system with special circuit board arrangement |
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| WO2003083041A2 (en) | 2003-10-09 |
| WO2003083041A3 (en) | 2003-12-04 |
| WO2003083041A8 (en) | 2004-09-16 |
| JP2005520566A (ja) | 2005-07-14 |
| EP1494693A4 (en) | 2006-08-02 |
| EP1494693B1 (en) | 2010-12-08 |
| AU2002334799A1 (en) | 2003-10-13 |
| EP1494693A2 (en) | 2005-01-12 |
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