JP2005519118A5 - - Google Patents
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- Publication number
- JP2005519118A5 JP2005519118A5 JP2003573002A JP2003573002A JP2005519118A5 JP 2005519118 A5 JP2005519118 A5 JP 2005519118A5 JP 2003573002 A JP2003573002 A JP 2003573002A JP 2003573002 A JP2003573002 A JP 2003573002A JP 2005519118 A5 JP2005519118 A5 JP 2005519118A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl
- aryl
- heteroaryl
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 91
- 150000001875 compounds Chemical class 0.000 claims 62
- 125000003118 aryl group Chemical group 0.000 claims 57
- 125000000217 alkyl group Chemical group 0.000 claims 55
- 125000001072 heteroaryl group Chemical group 0.000 claims 55
- 229910052739 hydrogen Inorganic materials 0.000 claims 49
- 239000001257 hydrogen Substances 0.000 claims 49
- 229910052760 oxygen Inorganic materials 0.000 claims 45
- 150000002431 hydrogen Chemical class 0.000 claims 36
- 239000000126 substance Substances 0.000 claims 33
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 29
- 239000001301 oxygen Substances 0.000 claims 29
- 229910052799 carbon Inorganic materials 0.000 claims 27
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 27
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 22
- 229910052736 halogen Inorganic materials 0.000 claims 17
- 150000002367 halogens Chemical class 0.000 claims 17
- 125000001931 aliphatic group Chemical group 0.000 claims 15
- 125000003545 alkoxy group Chemical group 0.000 claims 15
- 125000001769 aryl amino group Chemical group 0.000 claims 15
- 125000004986 diarylamino group Chemical group 0.000 claims 15
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 13
- 125000004104 aryloxy group Chemical group 0.000 claims 13
- 125000004663 dialkyl amino group Chemical group 0.000 claims 12
- -1 2-methoxy-2-propyl Chemical group 0.000 claims 11
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 11
- 238000004519 manufacturing process Methods 0.000 claims 8
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 claims 6
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims 6
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 claims 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 6
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims 6
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 claims 6
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 claims 6
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 claims 6
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 claims 6
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 5
- 229910052801 chlorine Inorganic materials 0.000 claims 5
- 239000000460 chlorine Substances 0.000 claims 5
- 239000002904 solvent Substances 0.000 claims 5
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 claims 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 3
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 claims 3
- 229910052744 lithium Inorganic materials 0.000 claims 3
- 125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 claims 2
- BZLVMXJERCGZMT-UHFFFAOYSA-N Methyl tert-butyl ether Chemical compound COC(C)(C)C BZLVMXJERCGZMT-UHFFFAOYSA-N 0.000 claims 2
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 claims 2
- 150000002009 diols Chemical class 0.000 claims 2
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 claims 2
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 claims 2
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 claims 2
- YSEUEZAVUMLQHK-WOJBJXKFSA-N (1r,2r)-2-n,2-n-bis[(4-bromophenyl)methyl]cyclohexane-1,2-diamine Chemical compound N[C@@H]1CCCC[C@H]1N(CC=1C=CC(Br)=CC=1)CC1=CC=C(Br)C=C1 YSEUEZAVUMLQHK-WOJBJXKFSA-N 0.000 claims 1
- LQJAICQUOQTPOR-FGZHOGPDSA-N (1r,2r)-2-n,2-n-bis[(4-methoxyphenyl)methyl]cyclohexane-1,2-diamine Chemical compound C1=CC(OC)=CC=C1CN([C@H]1[C@@H](CCCC1)N)CC1=CC=C(OC)C=C1 LQJAICQUOQTPOR-FGZHOGPDSA-N 0.000 claims 1
- SXCIGPQHVCQIFJ-WOJBJXKFSA-N (1r,2r)-2-n,2-n-dibenzylcyclohexane-1,2-diamine Chemical compound N[C@@H]1CCCC[C@H]1N(CC=1C=CC=CC=1)CC1=CC=CC=C1 SXCIGPQHVCQIFJ-WOJBJXKFSA-N 0.000 claims 1
- 125000006281 4-bromobenzyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1Br)C([H])([H])* 0.000 claims 1
- 150000004985 diamines Chemical class 0.000 claims 1
- NBNHZZVUWIWERN-JGTWLXFQSA-N C=CC[Si](N(Cc(cc1)ccc1Br)[C@H]1[C@H]2CCCC1)([N]2(Cc(cc1)ccc1Br)#C)Cl Chemical compound C=CC[Si](N(Cc(cc1)ccc1Br)[C@H]1[C@H]2CCCC1)([N]2(Cc(cc1)ccc1Br)#C)Cl NBNHZZVUWIWERN-JGTWLXFQSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36098702P | 2002-03-01 | 2002-03-01 | |
| US36981202P | 2002-04-04 | 2002-04-04 | |
| PCT/US2003/006308 WO2003074534A1 (en) | 2002-03-01 | 2003-03-03 | Reagents for asymmetric allylation, aldol, and tandem aldol and allylation reactions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005519118A JP2005519118A (ja) | 2005-06-30 |
| JP2005519118A5 true JP2005519118A5 (https=) | 2006-03-16 |
Family
ID=27791660
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003573002A Pending JP2005519118A (ja) | 2002-03-01 | 2003-03-03 | 不斉アリル化、アルドール、およびタンデムアルドールおよびアリル化反応のための試薬 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7534905B2 (https=) |
| EP (1) | EP1480988A4 (https=) |
| JP (1) | JP2005519118A (https=) |
| CN (1) | CN1639172A (https=) |
| AU (1) | AU2003219965A1 (https=) |
| CA (1) | CA2477444A1 (https=) |
| WO (1) | WO2003074534A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104761466A (zh) | 2007-05-29 | 2015-07-08 | 英特拉克森公司 | 通过蜕皮素受体复合物调节外源性基因表达的手性二酰基肼配体 |
| US7619049B1 (en) * | 2009-04-13 | 2009-11-17 | Formosa Plastics Corporation, U.S.A. | Cyclic organosilicon compounds as electron donors for polyolefin catalysts |
| US8536360B2 (en) | 2011-01-20 | 2013-09-17 | The Trustees Of Columbia University In The City Of New York | Compositions and methods for stereoselective aldehyde allylation and crotylation |
| CA3061802C (en) | 2011-09-08 | 2022-04-05 | Intrexon Corporation | Crystalline diacylhydrazine and the use thereof |
| US10654947B2 (en) | 2011-10-28 | 2020-05-19 | Formosa Plastics Corporation, Usa | Cyclic organosilicon compounds as electron donors in Zeigler-Natta catalyst systems for producing propylene polymer having high melt-flowability |
| CN105461743B (zh) * | 2016-01-06 | 2017-12-05 | 山西大学 | 双杂五元环对称芳基衍生物及其制备方法 |
-
2003
- 2003-03-03 CA CA002477444A patent/CA2477444A1/en not_active Abandoned
- 2003-03-03 JP JP2003573002A patent/JP2005519118A/ja active Pending
- 2003-03-03 US US10/504,831 patent/US7534905B2/en not_active Expired - Fee Related
- 2003-03-03 AU AU2003219965A patent/AU2003219965A1/en not_active Abandoned
- 2003-03-03 EP EP03716252A patent/EP1480988A4/en not_active Withdrawn
- 2003-03-03 WO PCT/US2003/006308 patent/WO2003074534A1/en not_active Ceased
- 2003-03-03 CN CNA038050196A patent/CN1639172A/zh active Pending
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