JP2005513096A - シクロスポリン、親水性界面活性剤及び親油性界面活性剤を含んで成る医薬組成物 - Google Patents

シクロスポリン、親水性界面活性剤及び親油性界面活性剤を含んで成る医薬組成物 Download PDF

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Publication number
JP2005513096A
JP2005513096A JP2003554163A JP2003554163A JP2005513096A JP 2005513096 A JP2005513096 A JP 2005513096A JP 2003554163 A JP2003554163 A JP 2003554163A JP 2003554163 A JP2003554163 A JP 2003554163A JP 2005513096 A JP2005513096 A JP 2005513096A
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JP
Japan
Prior art keywords
cyclosporine
surfactant
composition
hydrophilic
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2003554163A
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English (en)
Japanese (ja)
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JP2005513096A5 (https=
Inventor
チャールズ シャーマン，バーナード
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Individual
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Individual
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Filing date
Publication date
Priority claimed from NZ51626901A external-priority patent/NZ516269A/en
Priority claimed from NZ51983702A external-priority patent/NZ519837A/en
Application filed by Individual filed Critical Individual
Publication of JP2005513096A publication Critical patent/JP2005513096A/ja
Publication of JP2005513096A5 publication Critical patent/JP2005513096A5/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2003554163A 2001-12-20 2002-12-19 シクロスポリン、親水性界面活性剤及び親油性界面活性剤を含んで成る医薬組成物 Pending JP2005513096A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NZ51626901A NZ516269A (en) 2001-12-20 2001-12-20 Pharmaceutical compositions comprising cyclosporine
NZ51983702A NZ519837A (en) 2002-06-28 2002-06-28 Pharmaceutical compositions comprising a cyclosporin or cyclosporin derivative
PCT/CA2002/001968 WO2003053404A1 (en) 2001-12-20 2002-12-19 Pharmaceutical compositions comprising a cyclosporin, a hydrophilic surfactant and a lipophilic surfactant

Publications (2)

Publication Number Publication Date
JP2005513096A true JP2005513096A (ja) 2005-05-12
JP2005513096A5 JP2005513096A5 (https=) 2006-02-09

Family

ID=26652297

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003554163A Pending JP2005513096A (ja) 2001-12-20 2002-12-19 シクロスポリン、親水性界面活性剤及び親油性界面活性剤を含んで成る医薬組成物

Country Status (6)

Country Link
US (2) US20050129718A1 (https=)
EP (1) EP1455753A1 (https=)
JP (1) JP2005513096A (https=)
BR (1) BR0215187A (https=)
CA (1) CA2471241A1 (https=)
WO (1) WO2003053404A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011207809A (ja) * 2010-03-30 2011-10-20 Nakanihon Capsule Co Ltd ソフトカプセル用の充填組成物
JP2014513708A (ja) * 2011-05-20 2014-06-05 アベンティス・ファーマスーティカルズ・インコーポレイテツド フェキソフェナジンを含む医薬組成物
JP2022514991A (ja) * 2018-12-10 2022-02-16 ハロー・サイエンス・エル・エル・シー 安定な麻酔薬製剤および関連する剤形

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2604943C (en) 2005-04-15 2013-09-17 Clarus Therapeutics, Inc. Pharmaceutical delivery systems for hydrophobic drugs and compositions comprising same
US8492369B2 (en) 2010-04-12 2013-07-23 Clarus Therapeutics Inc Oral testosterone ester formulations and methods of treating testosterone deficiency comprising same
US20070015691A1 (en) 2005-07-13 2007-01-18 Allergan, Inc. Cyclosporin compositions
US20070015693A1 (en) * 2005-07-13 2007-01-18 Allergan, Inc. Cyclosporin compositions
US7288520B2 (en) * 2005-07-13 2007-10-30 Allergan, Inc. Cyclosporin compositions
US7297679B2 (en) * 2005-07-13 2007-11-20 Allergan, Inc. Cyclosporin compositions
US7276476B2 (en) * 2005-07-13 2007-10-02 Allergan, Inc. Cyclosporin compositions
US7202209B2 (en) 2005-07-13 2007-04-10 Allergan, Inc. Cyclosporin compositions
US7501393B2 (en) 2005-07-27 2009-03-10 Allergan, Inc. Pharmaceutical compositions comprising cyclosporins
US7745400B2 (en) * 2005-10-14 2010-06-29 Gregg Feinerman Prevention and treatment of ocular side effects with a cyclosporin
US9839667B2 (en) 2005-10-14 2017-12-12 Allergan, Inc. Prevention and treatment of ocular side effects with a cyclosporin
CA2642656A1 (en) * 2006-02-22 2007-09-07 Novartis Pharma Ag System for delivering nebulized cyclosporine and methods of treatment
EP2079456B1 (en) 2007-04-04 2012-12-05 Sigmoid Pharma Limited Pharmaceutical cyclosporin compositions
ES2649112T3 (es) 2009-05-18 2018-01-10 Sigmoid Pharma Limited Composición que comprende gotas de aceite
CN107582526A (zh) 2009-08-12 2018-01-16 希格默伊德药业有限公司 包含聚合物基质和油相的免疫调节组合物
GB201020032D0 (en) 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
GB201304662D0 (en) 2013-03-14 2013-05-01 Sigmoid Pharma Ltd Compositions
US10245273B2 (en) 2013-12-26 2019-04-02 Clarus Therapeutics, Inc. Oral pharmaceutical products and methods of use combining testosterone esters with hypolipidemic agents
EP3881829A1 (en) 2014-11-07 2021-09-22 Sublimity Therapeutics Limited Compositions comprising cyclosporin
US11564933B2 (en) 2019-04-12 2023-01-31 Tolmar, Inc. Methods of treating testosterone deficiency

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998048779A1 (en) * 1997-04-29 1998-11-05 Bernard Charles Sherman Emulsion preconcentrate comprising a cyclosporin and acetylated monoglyceride
JP2001516351A (ja) * 1997-03-12 2001-09-25 アボツト・ラボラトリーズ シクロスポリンの投与のための親水性二成分系

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI65914C (fi) * 1978-03-07 1984-08-10 Sandoz Ag Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a
GB2222770B (en) * 1988-09-16 1992-07-29 Sandoz Ltd Pharmaceutical compositions containing cyclosporins
NZ247516A (en) * 1993-04-28 1995-02-24 Bernard Charles Sherman Water dispersible pharmaceutical compositions comprising drug dissolved in solvent system comprising at least one alcohol and at least one surfactant
US5834017A (en) * 1995-08-25 1998-11-10 Sangstat Medical Corporation Oral cyclopsporin formulations
US5858401A (en) * 1996-01-22 1999-01-12 Sidmak Laboratories, Inc. Pharmaceutical composition for cyclosporines
US5798333A (en) * 1996-09-17 1998-08-25 Sherman; Bernard C. Water-soluble concentrates containing cyclosporins
CA2285983A1 (en) * 1997-04-29 1998-11-05 Bernard Charles Sherman Emulsion preconcentrate comprising a cyclosporin and acetylated monoglyceride
IN188719B (https=) * 1997-09-08 2002-11-02 Panacea Biotec Ltd
US6008191A (en) * 1997-09-08 1999-12-28 Panacea Biotec Limited Pharmaceutical compositions containing cyclosporin
US6187747B1 (en) * 1997-09-08 2001-02-13 Panacea Biotech Limited Pharmaceutical composition comprising cyclosporin
CN1236813C (zh) * 1998-12-11 2006-01-18 药品处理公司 水难溶性药物的自乳化组合物
US6294192B1 (en) * 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
US6057289A (en) * 1999-04-30 2000-05-02 Pharmasolutions, Inc. Pharmaceutical composition comprising cyclosporin in association with a carrier in a self-emulsifying drug delivery system
GB9912476D0 (en) * 1999-05-28 1999-07-28 Novartis Ag Organic compounds
GB2362573A (en) * 2000-05-25 2001-11-28 Cipla Ltd Cyclosporin formulation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001516351A (ja) * 1997-03-12 2001-09-25 アボツト・ラボラトリーズ シクロスポリンの投与のための親水性二成分系
WO1998048779A1 (en) * 1997-04-29 1998-11-05 Bernard Charles Sherman Emulsion preconcentrate comprising a cyclosporin and acetylated monoglyceride

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011207809A (ja) * 2010-03-30 2011-10-20 Nakanihon Capsule Co Ltd ソフトカプセル用の充填組成物
JP2014513708A (ja) * 2011-05-20 2014-06-05 アベンティス・ファーマスーティカルズ・インコーポレイテツド フェキソフェナジンを含む医薬組成物
JP2022514991A (ja) * 2018-12-10 2022-02-16 ハロー・サイエンス・エル・エル・シー 安定な麻酔薬製剤および関連する剤形

Also Published As

Publication number Publication date
AU2002351597A1 (en) 2003-07-09
CA2471241A1 (en) 2003-07-03
WO2003053404A1 (en) 2003-07-03
EP1455753A1 (en) 2004-09-15
BR0215187A (pt) 2004-11-16
US20050129718A1 (en) 2005-06-16
US20110028406A1 (en) 2011-02-03

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