JP2005513096A5 - - Google Patents
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- Publication number
- JP2005513096A5 JP2005513096A5 JP2003554163A JP2003554163A JP2005513096A5 JP 2005513096 A5 JP2005513096 A5 JP 2005513096A5 JP 2003554163 A JP2003554163 A JP 2003554163A JP 2003554163 A JP2003554163 A JP 2003554163A JP 2005513096 A5 JP2005513096 A5 JP 2005513096A5
- Authority
- JP
- Japan
- Prior art keywords
- cyclosporine
- solvent
- surfactant
- derivative
- lipophilic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 claims 10
- 239000004094 surface-active agent Substances 0.000 claims 6
- 108010036949 Cyclosporine Proteins 0.000 claims 5
- 229960001265 ciclosporin Drugs 0.000 claims 5
- 229930182912 cyclosporin Natural products 0.000 claims 5
- 239000002904 solvent Substances 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 238000009835 boiling Methods 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ51626901A NZ516269A (en) | 2001-12-20 | 2001-12-20 | Pharmaceutical compositions comprising cyclosporine |
| NZ51983702A NZ519837A (en) | 2002-06-28 | 2002-06-28 | Pharmaceutical compositions comprising a cyclosporin or cyclosporin derivative |
| PCT/CA2002/001968 WO2003053404A1 (en) | 2001-12-20 | 2002-12-19 | Pharmaceutical compositions comprising a cyclosporin, a hydrophilic surfactant and a lipophilic surfactant |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005513096A JP2005513096A (ja) | 2005-05-12 |
| JP2005513096A5 true JP2005513096A5 (https=) | 2006-02-09 |
Family
ID=26652297
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003554163A Pending JP2005513096A (ja) | 2001-12-20 | 2002-12-19 | シクロスポリン、親水性界面活性剤及び親油性界面活性剤を含んで成る医薬組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20050129718A1 (https=) |
| EP (1) | EP1455753A1 (https=) |
| JP (1) | JP2005513096A (https=) |
| BR (1) | BR0215187A (https=) |
| CA (1) | CA2471241A1 (https=) |
| WO (1) | WO2003053404A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2604943C (en) | 2005-04-15 | 2013-09-17 | Clarus Therapeutics, Inc. | Pharmaceutical delivery systems for hydrophobic drugs and compositions comprising same |
| US8492369B2 (en) | 2010-04-12 | 2013-07-23 | Clarus Therapeutics Inc | Oral testosterone ester formulations and methods of treating testosterone deficiency comprising same |
| US7288520B2 (en) * | 2005-07-13 | 2007-10-30 | Allergan, Inc. | Cyclosporin compositions |
| US20070015691A1 (en) | 2005-07-13 | 2007-01-18 | Allergan, Inc. | Cyclosporin compositions |
| US7276476B2 (en) * | 2005-07-13 | 2007-10-02 | Allergan, Inc. | Cyclosporin compositions |
| US7297679B2 (en) | 2005-07-13 | 2007-11-20 | Allergan, Inc. | Cyclosporin compositions |
| US7202209B2 (en) | 2005-07-13 | 2007-04-10 | Allergan, Inc. | Cyclosporin compositions |
| US20070015693A1 (en) * | 2005-07-13 | 2007-01-18 | Allergan, Inc. | Cyclosporin compositions |
| US7501393B2 (en) | 2005-07-27 | 2009-03-10 | Allergan, Inc. | Pharmaceutical compositions comprising cyclosporins |
| US9839667B2 (en) | 2005-10-14 | 2017-12-12 | Allergan, Inc. | Prevention and treatment of ocular side effects with a cyclosporin |
| US7745400B2 (en) * | 2005-10-14 | 2010-06-29 | Gregg Feinerman | Prevention and treatment of ocular side effects with a cyclosporin |
| AU2007221196B2 (en) * | 2006-02-22 | 2011-08-04 | Novartis Pharma Ag | System for delivering nebulized cyclosporine and methods of treatment |
| ES2393814T3 (es) | 2007-04-04 | 2012-12-28 | Sigmoid Pharma Limited | Una composición farmacéutica oral |
| ES2530049T3 (es) | 2009-05-18 | 2015-02-26 | Sigmoid Pharma Limited | Composición que comprende gotas de aceite |
| CN102573802A (zh) | 2009-08-12 | 2012-07-11 | 希格默伊德药业有限公司 | 包含聚合物基质和油相的免疫调节组合物 |
| JP5283654B2 (ja) * | 2010-03-30 | 2013-09-04 | 中日本カプセル 株式会社 | ソフトカプセル用の充填組成物 |
| GB201020032D0 (en) | 2010-11-25 | 2011-01-12 | Sigmoid Pharma Ltd | Composition |
| BR112013029778A2 (pt) * | 2011-05-20 | 2017-01-17 | Aventis Pharma Inc | composição farmacêutica que compreende fexofenadina |
| GB201304662D0 (en) | 2013-03-14 | 2013-05-01 | Sigmoid Pharma Ltd | Compositions |
| US10245273B2 (en) | 2013-12-26 | 2019-04-02 | Clarus Therapeutics, Inc. | Oral pharmaceutical products and methods of use combining testosterone esters with hypolipidemic agents |
| JP6716582B2 (ja) | 2014-11-07 | 2020-07-01 | サブリミティ・セラピューティクス・リミテッドＳｕｂｌｉｍｉｔｙ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｌｉｍｉｔｅｄ | シクロスポリンを含む組成物 |
| CN113613632A (zh) * | 2018-12-10 | 2021-11-05 | 光环科学有限责任公司 | 麻醉剂的稳定制剂和相关剂型 |
| US11564933B2 (en) | 2019-04-12 | 2023-01-31 | Tolmar, Inc. | Methods of treating testosterone deficiency |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2907460A1 (de) * | 1978-03-07 | 1979-09-13 | Sandoz Ag | Neue resorbierbare galenische kompositionen |
| KR0148748B1 (ko) * | 1988-09-16 | 1998-08-17 | 장 크라메르, 한스 루돌프 하우스 | 사이클로스포린을 함유하는 약학조성물 |
| NZ247516A (en) * | 1993-04-28 | 1995-02-24 | Bernard Charles Sherman | Water dispersible pharmaceutical compositions comprising drug dissolved in solvent system comprising at least one alcohol and at least one surfactant |
| US5834017A (en) * | 1995-08-25 | 1998-11-10 | Sangstat Medical Corporation | Oral cyclopsporin formulations |
| US5858401A (en) * | 1996-01-22 | 1999-01-12 | Sidmak Laboratories, Inc. | Pharmaceutical composition for cyclosporines |
| US5798333A (en) * | 1996-09-17 | 1998-08-25 | Sherman; Bernard C. | Water-soluble concentrates containing cyclosporins |
| NZ337316A (en) * | 1997-03-12 | 2001-06-29 | Abbott Lab | Hydrophilic binary systems comprising cyclosporine, hydrophilic phase and a surfactant for the administration of cyclosporine |
| NZ314702A (en) * | 1997-04-29 | 1998-07-28 | Bernard Charles Sherman | Pharmaceutical composition comprising a cyclosporin in a solvent system of acetylated monoglycerides and a surfactant and optionally a hydrophilic solvent |
| AR012627A1 (es) * | 1997-04-29 | 2000-11-08 | Sherman Bernard Charles | Pre-concentrado de emulsion que comprende una ciclosporina y monoglicerido acetilado |
| US6008191A (en) * | 1997-09-08 | 1999-12-28 | Panacea Biotec Limited | Pharmaceutical compositions containing cyclosporin |
| US6187747B1 (en) * | 1997-09-08 | 2001-02-13 | Panacea Biotech Limited | Pharmaceutical composition comprising cyclosporin |
| IN188719B (https=) * | 1997-09-08 | 2002-11-02 | Panacea Biotec Ltd | |
| US6638522B1 (en) * | 1998-12-11 | 2003-10-28 | Pharmasolutions, Inc. | Microemulsion concentrate composition of cyclosporin |
| US6294192B1 (en) * | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| US6057289A (en) * | 1999-04-30 | 2000-05-02 | Pharmasolutions, Inc. | Pharmaceutical composition comprising cyclosporin in association with a carrier in a self-emulsifying drug delivery system |
| GB9912476D0 (en) * | 1999-05-28 | 1999-07-28 | Novartis Ag | Organic compounds |
| GB2362573A (en) * | 2000-05-25 | 2001-11-28 | Cipla Ltd | Cyclosporin formulation |
-
2002
- 2002-12-19 CA CA002471241A patent/CA2471241A1/en not_active Abandoned
- 2002-12-19 EP EP02787270A patent/EP1455753A1/en not_active Withdrawn
- 2002-12-19 JP JP2003554163A patent/JP2005513096A/ja active Pending
- 2002-12-19 BR BR0215187-1A patent/BR0215187A/pt not_active Application Discontinuation
- 2002-12-19 US US10/499,709 patent/US20050129718A1/en not_active Abandoned
- 2002-12-19 WO PCT/CA2002/001968 patent/WO2003053404A1/en not_active Ceased
-
2010
- 2010-10-13 US US12/903,859 patent/US20110028406A1/en not_active Abandoned
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