JP2005511662A5 - - Google Patents
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- Publication number
- JP2005511662A5 JP2005511662A5 JP2003548874A JP2003548874A JP2005511662A5 JP 2005511662 A5 JP2005511662 A5 JP 2005511662A5 JP 2003548874 A JP2003548874 A JP 2003548874A JP 2003548874 A JP2003548874 A JP 2003548874A JP 2005511662 A5 JP2005511662 A5 JP 2005511662A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- composition
- amino acid
- composition according
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000036639 antigens Human genes 0.000 claims 32
- 108091007433 antigens Proteins 0.000 claims 32
- 239000000427 antigen Substances 0.000 claims 30
- 125000003275 alpha amino acid group Chemical group 0.000 claims 11
- 102000004169 proteins and genes Human genes 0.000 claims 10
- 108090000623 proteins and genes Proteins 0.000 claims 10
- 241000588653 Neisseria Species 0.000 claims 5
- 150000001413 amino acids Chemical class 0.000 claims 4
- 239000003053 toxin Substances 0.000 claims 4
- 231100000765 toxin Toxicity 0.000 claims 4
- 150000001720 carbohydrates Chemical class 0.000 claims 3
- 241000588724 Escherichia coli Species 0.000 claims 2
- 125000001429 N-terminal alpha-amino-acid group Chemical group 0.000 claims 2
- 101100038645 Streptomyces griseus rppA gene Proteins 0.000 claims 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 241000588832 Bordetella pertussis Species 0.000 claims 1
- 125000001433 C-terminal amino-acid group Chemical group 0.000 claims 1
- 241001647372 Chlamydia pneumoniae Species 0.000 claims 1
- 241000606153 Chlamydia trachomatis Species 0.000 claims 1
- 102000009016 Cholera Toxin Human genes 0.000 claims 1
- 108010049048 Cholera Toxin Proteins 0.000 claims 1
- 101710146739 Enterotoxin Proteins 0.000 claims 1
- 241000606768 Haemophilus influenzae Species 0.000 claims 1
- 241000590002 Helicobacter pylori Species 0.000 claims 1
- 241000711549 Hepacivirus C Species 0.000 claims 1
- 241000700721 Hepatitis B virus Species 0.000 claims 1
- 241000709721 Hepatovirus A Species 0.000 claims 1
- 201000005505 Measles Diseases 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 241000588655 Moraxella catarrhalis Species 0.000 claims 1
- 208000005647 Mumps Diseases 0.000 claims 1
- 101100459189 Neisseria meningitidis serogroup B (strain MC58) mutS gene Proteins 0.000 claims 1
- 208000000474 Poliomyelitis Diseases 0.000 claims 1
- 241000605862 Porphyromonas gingivalis Species 0.000 claims 1
- 206010037742 Rabies Diseases 0.000 claims 1
- 241000191967 Staphylococcus aureus Species 0.000 claims 1
- 241000193985 Streptococcus agalactiae Species 0.000 claims 1
- 101000870438 Streptococcus gordonii UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase stabilizing protein GtfB Proteins 0.000 claims 1
- 241000193998 Streptococcus pneumoniae Species 0.000 claims 1
- 241000193996 Streptococcus pyogenes Species 0.000 claims 1
- 206010043376 Tetanus Diseases 0.000 claims 1
- 101000645119 Vibrio campbellii (strain ATCC BAA-1116 / BB120) Nucleotide-binding protein VIBHAR_03667 Proteins 0.000 claims 1
- 229940038705 chlamydia trachomatis Drugs 0.000 claims 1
- 206010013023 diphtheria Diseases 0.000 claims 1
- 239000000147 enterotoxin Substances 0.000 claims 1
- 231100000655 enterotoxin Toxicity 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 229940047650 haemophilus influenzae Drugs 0.000 claims 1
- 229940037467 helicobacter pylori Drugs 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000002163 immunogen Effects 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 206010022000 influenza Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 208000010805 mumps infectious disease Diseases 0.000 claims 1
- 230000035772 mutation Effects 0.000 claims 1
- 239000002510 pyrogen Substances 0.000 claims 1
- 201000005404 rubella Diseases 0.000 claims 1
- 229940031000 streptococcus pneumoniae Drugs 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0129007.1A GB0129007D0 (en) | 2001-12-04 | 2001-12-04 | Adjuvanted antigenic meningococcal compositions |
| PCT/IB2002/005662 WO2003047619A2 (en) | 2001-12-04 | 2002-12-04 | Adjuvanted antigenic meningococcal compositions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009096521A Division JP2009155344A (ja) | 2001-12-04 | 2009-04-10 | アジュバント化された抗原性髄膜炎菌性組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005511662A JP2005511662A (ja) | 2005-04-28 |
| JP2005511662A5 true JP2005511662A5 (enExample) | 2006-01-19 |
| JP4414226B2 JP4414226B2 (ja) | 2010-02-10 |
Family
ID=9926977
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003548874A Expired - Fee Related JP4414226B2 (ja) | 2001-12-04 | 2002-12-04 | アジュバント化された抗原性髄膜炎菌性組成物 |
| JP2009096521A Withdrawn JP2009155344A (ja) | 2001-12-04 | 2009-04-10 | アジュバント化された抗原性髄膜炎菌性組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009096521A Withdrawn JP2009155344A (ja) | 2001-12-04 | 2009-04-10 | アジュバント化された抗原性髄膜炎菌性組成物 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20060008476A1 (enExample) |
| EP (1) | EP1448230B1 (enExample) |
| JP (2) | JP4414226B2 (enExample) |
| AP (1) | AP2004003074A0 (enExample) |
| AT (1) | ATE485055T1 (enExample) |
| AU (1) | AU2002353417A1 (enExample) |
| CA (1) | CA2468935C (enExample) |
| CY (1) | CY1111114T1 (enExample) |
| DE (1) | DE60238075D1 (enExample) |
| GB (1) | GB0129007D0 (enExample) |
| WO (1) | WO2003047619A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9513371D0 (en) * | 1995-06-30 | 1995-09-06 | Biocine Spa | Immunogenic detoxified mutant toxins |
| CN101139590B (zh) * | 2000-02-28 | 2012-07-18 | 启龙股份公司 | 奈瑟球菌蛋白质的杂交表达 |
| US7285281B2 (en) * | 2001-06-07 | 2007-10-23 | Wyeth Holdings Corporation | Mutant forms of cholera holotoxin as an adjuvant |
| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| WO2003094960A2 (en) * | 2002-05-14 | 2003-11-20 | Chiron Srl | Mucosal combination vaccines for bacterial meningitis |
| GB0302218D0 (en) | 2003-01-30 | 2003-03-05 | Chiron Sri | Vaccine formulation & Mucosal delivery |
| GB0227346D0 (en) * | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
| ATE506963T1 (de) * | 2003-10-02 | 2011-05-15 | Novartis Vaccines & Diagnostic | Kombinationsimpfstoffe gegen meningitis |
| AR064642A1 (es) | 2006-12-22 | 2009-04-15 | Wyeth Corp | Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi |
| ES2797504T3 (es) | 2009-03-24 | 2020-12-02 | Glaxosmithkline Biologicals Sa | Proteína de enlace del factor H meningocócico utilizada como adyuvante |
| PT3246044T (pt) | 2010-08-23 | 2021-02-15 | Wyeth Llc | Formulações estáveis de antigénios de rlp2086 de neisseria meningitidis |
| AU2011300409B2 (en) | 2010-09-10 | 2015-03-26 | Wyeth Llc | Non-lipidated variants of Neisseria meningitidis ORF2086 antigens |
| US20130287808A1 (en) * | 2010-11-05 | 2013-10-31 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Vaccines for preventing meningococcal infections |
| GB201102090D0 (en) * | 2011-02-08 | 2011-03-23 | Univ Sheffield | Antigenic polypeptide |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| US8986710B2 (en) | 2012-03-09 | 2015-03-24 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| AU2013295242C1 (en) | 2012-07-27 | 2018-08-09 | Institut National De La Sante Et De La Recherche Medicale | CD147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia |
| WO2014136064A2 (en) | 2013-03-08 | 2014-09-12 | Pfizer Inc. | Immunogenic fusion polypeptides |
| MX369534B (es) | 2013-09-08 | 2019-11-11 | Pfizer | Composiciones de neisseria meningitidis y sus metodos. |
| RU2723045C2 (ru) | 2015-02-19 | 2020-06-08 | Пфайзер Инк. | Композиции neisseria meningitidis и способы их получения |
| SG10202111092UA (en) | 2017-01-31 | 2021-11-29 | Pfizer | Neisseria meningitidis compositions and methods thereof |
| CN113453709A (zh) * | 2018-12-21 | 2021-09-28 | 格里菲斯大学 | 用于引发免疫应答的组合物、方法和用途 |
| CA3155669A1 (en) | 2019-09-27 | 2021-04-01 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| US20220348645A1 (en) * | 2019-10-01 | 2022-11-03 | Beth Israel Deaconess Medical Center, Inc. | Conformation-specific antibodies that bind nuclear factor kappa-light-chain-enhancer of activated b cells |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5153312A (en) * | 1990-09-28 | 1992-10-06 | American Cyanamid Company | Oligosaccharide conjugate vaccines |
| ATE476508T1 (de) * | 1997-11-06 | 2010-08-15 | Novartis Vaccines & Diagnostic | Neisseriale antigene |
| GB9726398D0 (en) * | 1997-12-12 | 1998-02-11 | Isis Innovation | Polypeptide and coding sequences |
| SG152917A1 (en) * | 1998-01-14 | 2009-06-29 | Chiron Srl | Neisseria meningitidis antigens |
| ES2293735T3 (es) * | 1998-09-30 | 2008-03-16 | Wyeth Holdings Corporation | Holotoxina del colera mutante como coadyuvante. |
| US7384640B1 (en) * | 1999-09-30 | 2008-06-10 | Wyeth Holdings Corporation | Mutant cholera holotoxin as an adjuvant |
| AR045702A1 (es) * | 2001-10-03 | 2005-11-09 | Chiron Corp | Composiciones de adyuvantes. |
-
2001
- 2001-12-04 GB GBGB0129007.1A patent/GB0129007D0/en not_active Ceased
-
2002
- 2002-12-04 AU AU2002353417A patent/AU2002353417A1/en not_active Abandoned
- 2002-12-04 JP JP2003548874A patent/JP4414226B2/ja not_active Expired - Fee Related
- 2002-12-04 AT AT02788442T patent/ATE485055T1/de not_active IP Right Cessation
- 2002-12-04 CA CA2468935A patent/CA2468935C/en not_active Expired - Fee Related
- 2002-12-04 WO PCT/IB2002/005662 patent/WO2003047619A2/en not_active Ceased
- 2002-12-04 US US10/497,709 patent/US20060008476A1/en not_active Abandoned
- 2002-12-04 AP APAP/P/2004/003074A patent/AP2004003074A0/en unknown
- 2002-12-04 DE DE60238075T patent/DE60238075D1/de not_active Expired - Lifetime
- 2002-12-04 EP EP02788442A patent/EP1448230B1/en not_active Expired - Lifetime
-
2009
- 2009-04-10 JP JP2009096521A patent/JP2009155344A/ja not_active Withdrawn
-
2010
- 2010-05-25 US US12/787,366 patent/US20100233205A1/en not_active Abandoned
-
2011
- 2011-01-18 CY CY20111100056T patent/CY1111114T1/el unknown
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