JP2005511612A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2005511612A5 JP2005511612A5 JP2003542191A JP2003542191A JP2005511612A5 JP 2005511612 A5 JP2005511612 A5 JP 2005511612A5 JP 2003542191 A JP2003542191 A JP 2003542191A JP 2003542191 A JP2003542191 A JP 2003542191A JP 2005511612 A5 JP2005511612 A5 JP 2005511612A5
- Authority
- JP
- Japan
- Prior art keywords
- valaciclovir hydrochloride
- anhydrous
- anhydrous crystalline
- spectrometer
- resolution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- ZCDDBUOENGJMLV-QRPNPIFTSA-N Valacyclovir hydrochloride Chemical compound Cl.N1C(N)=NC(=O)C2=C1N(COCCOC(=O)[C@@H](N)C(C)C)C=N2 ZCDDBUOENGJMLV-QRPNPIFTSA-N 0.000 claims 6
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims 2
- 238000005033 Fourier transform infrared spectroscopy Methods 0.000 claims 2
- 238000000862 absorption spectrum Methods 0.000 claims 2
- 229910052802 copper Inorganic materials 0.000 claims 2
- 239000010949 copper Substances 0.000 claims 2
- 239000013078 crystal Substances 0.000 claims 2
- 239000010439 graphite Substances 0.000 claims 2
- 229910002804 graphite Inorganic materials 0.000 claims 2
- 239000002480 mineral oil Substances 0.000 claims 2
- 235000010446 mineral oil Nutrition 0.000 claims 2
- 238000000634 powder X-ray diffraction Methods 0.000 claims 2
- 208000029433 Herpesviridae infectious disease Diseases 0.000 claims 1
- 238000002441 X-ray diffraction Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33331301P | 2001-11-05 | 2001-11-05 | |
| PCT/US2002/033926 WO2003040145A1 (en) | 2001-11-05 | 2002-10-23 | Anhydrous crystal form of valaciclovir hydrochloride |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005511612A JP2005511612A (ja) | 2005-04-28 |
| JP2005511612A5 true JP2005511612A5 (https=) | 2005-12-22 |
Family
ID=23302261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003542191A Pending JP2005511612A (ja) | 2001-11-05 | 2002-10-23 | 塩酸バラシクロビルの無水結晶形 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20040197396A1 (https=) |
| EP (1) | EP1453834A1 (https=) |
| JP (1) | JP2005511612A (https=) |
| AU (1) | AU2002348022B2 (https=) |
| CA (1) | CA2465420A1 (https=) |
| FR (1) | FR2831885A1 (https=) |
| GB (1) | GB2383038B (https=) |
| GR (1) | GR1004358B (https=) |
| IT (1) | ITRM20020555A1 (https=) |
| WO (1) | WO2003040145A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP0500753A3 (en) * | 2001-09-07 | 2006-05-29 | Teva Pharma | Crystalline forms of valacyclovir hydrochloride |
| WO2003040145A1 (en) * | 2001-11-05 | 2003-05-15 | Glaxo Group Limited | Anhydrous crystal form of valaciclovir hydrochloride |
| CN1307177C (zh) * | 2001-11-14 | 2007-03-28 | 特瓦制药工业有限公司 | 伐昔洛韦的合成与纯化 |
| US20050043329A1 (en) * | 2002-09-06 | 2005-02-24 | Shlomit Wizel | Crystalline forms of valacyclovir hydrochloride |
| AU2003289995A1 (en) * | 2002-12-09 | 2004-06-30 | Texcontor Etablissement | Anhydrous crystalline form of valacyclovir hydrochloride |
| WO2004106338A1 (en) * | 2003-05-30 | 2004-12-09 | Eos Eczacibasi Ozgun Kimyasal Urunler Sanayi Ve Ticaret A.S. | Novel crystalline forms of valacyclovir hydrochloride |
| KR100871621B1 (ko) * | 2003-06-02 | 2008-12-02 | 테바 파마슈티컬 인더스트리즈 리미티드 | 발라시클로비르 히드로클로라이드의 신규한 결정질 형태 |
| CN1331471C (zh) * | 2003-09-22 | 2007-08-15 | 陈云芳 | 盐酸万乃洛韦软胶囊组合物 |
| EP1746098A1 (en) | 2005-07-21 | 2007-01-24 | SOLMAG S.p.A. | Valacyclovir polymorphs and a process for the preparation thereof |
| US20080167325A1 (en) * | 2006-12-27 | 2008-07-10 | Bs Praveen Kumar | Valacyclovir compositions |
| JPWO2009031576A1 (ja) * | 2007-09-03 | 2010-12-16 | 味の素株式会社 | バラシクロビル塩酸塩結晶の製造方法 |
| WO2011158252A1 (en) | 2010-06-15 | 2011-12-22 | Matrix Laboratories Ltd | Process for the preparation of valacyclovir hydrochloride polymorphic form ii |
| CN105753868B (zh) * | 2016-04-12 | 2017-08-01 | 浙江理工大学 | 一种盐酸伐昔洛韦的半水合物及其制备方法 |
| CN112176011B (zh) * | 2020-10-26 | 2022-10-18 | 辰欣药业股份有限公司 | 一种酶催化制备盐酸伐昔洛韦的方法 |
| CN116754538B (zh) * | 2023-06-15 | 2024-05-07 | 深圳市新阳唯康科技有限公司 | 一种阿昔洛韦软膏的晶型定量方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4199574A (en) * | 1974-09-02 | 1980-04-22 | Burroughs Wellcome Co. | Methods and compositions for treating viral infections and guanine acyclic nucleosides |
| GB8719367D0 (en) * | 1987-08-15 | 1987-09-23 | Wellcome Found | Therapeutic compounds |
| GB9501178D0 (en) * | 1995-01-20 | 1995-03-08 | Wellcome Found | Guanine derivative |
| GB9501127D0 (en) * | 1995-01-20 | 1995-03-08 | Wellcome Found | Tablet |
| HUP0500753A3 (en) * | 2001-09-07 | 2006-05-29 | Teva Pharma | Crystalline forms of valacyclovir hydrochloride |
| WO2003040145A1 (en) * | 2001-11-05 | 2003-05-15 | Glaxo Group Limited | Anhydrous crystal form of valaciclovir hydrochloride |
| CN1307177C (zh) * | 2001-11-14 | 2007-03-28 | 特瓦制药工业有限公司 | 伐昔洛韦的合成与纯化 |
| US20050043329A1 (en) * | 2002-09-06 | 2005-02-24 | Shlomit Wizel | Crystalline forms of valacyclovir hydrochloride |
| EP1551838B1 (en) * | 2002-10-16 | 2006-08-09 | Teva Pharmaceutical Industries Ltd. | Method for reducing residual alcohols in crystalline valacyclovir hydrochloride |
| US20050059684A1 (en) * | 2002-10-16 | 2005-03-17 | Ben-Zion Dolitzky | Method for reducing residual alcohols in crystalline valacyclovir hydrochloride |
| AU2003289995A1 (en) * | 2002-12-09 | 2004-06-30 | Texcontor Etablissement | Anhydrous crystalline form of valacyclovir hydrochloride |
| WO2004106338A1 (en) * | 2003-05-30 | 2004-12-09 | Eos Eczacibasi Ozgun Kimyasal Urunler Sanayi Ve Ticaret A.S. | Novel crystalline forms of valacyclovir hydrochloride |
| KR100871621B1 (ko) * | 2003-06-02 | 2008-12-02 | 테바 파마슈티컬 인더스트리즈 리미티드 | 발라시클로비르 히드로클로라이드의 신규한 결정질 형태 |
| JP2007522130A (ja) * | 2004-01-21 | 2007-08-09 | テバ ファーマシューティカル インダストリーズ リミティド | 塩酸バラシクロビルの調製方法 |
| EP1746098A1 (en) * | 2005-07-21 | 2007-01-24 | SOLMAG S.p.A. | Valacyclovir polymorphs and a process for the preparation thereof |
| US20070112193A1 (en) * | 2005-11-14 | 2007-05-17 | Khunt Mayur D | Valacyclovir process |
-
2002
- 2002-10-23 WO PCT/US2002/033926 patent/WO2003040145A1/en not_active Ceased
- 2002-10-23 US US10/494,115 patent/US20040197396A1/en not_active Abandoned
- 2002-10-23 JP JP2003542191A patent/JP2005511612A/ja active Pending
- 2002-10-23 CA CA002465420A patent/CA2465420A1/en not_active Abandoned
- 2002-10-23 EP EP02784234A patent/EP1453834A1/en not_active Withdrawn
- 2002-10-23 AU AU2002348022A patent/AU2002348022B2/en not_active Ceased
- 2002-11-04 FR FR0213752A patent/FR2831885A1/fr not_active Withdrawn
- 2002-11-05 IT IT000555A patent/ITRM20020555A1/it unknown
- 2002-11-05 GR GR20020100478A patent/GR1004358B/el unknown
- 2002-11-05 GB GB0225771A patent/GB2383038B/en not_active Expired - Fee Related
-
2006
- 2006-10-24 US US11/552,218 patent/US20070093511A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2005511612A5 (https=) | ||
| JP2023145481A5 (https=) | ||
| JP2024001023A5 (https=) | ||
| RU2009136593A (ru) | Кристаллические формы 6-[2-(метилкарбамоил)фенилсульфанил]-3-е-[2-(пиридин-2-ил)этенил]индазола, пригодные для лечения аномального роста клеток у илекопитаюших | |
| JP2016065042A5 (https=) | ||
| JP2011168587A5 (https=) | ||
| JP2019501865A5 (https=) | ||
| RU2599785C3 (ru) | Кристаллические формы 5-хлор-n2-(2-изопропокси-5-метил-4-пиперидин-4-ил-фенил)-n4-[2-(пропан-2-сульфонил)-фенил]-пиримидин-2,4-диамина | |
| HRP20241443T1 (hr) | Kristalni oblici 7-klor-2-(4-(3-metoksiazetidin-1-il)cikloheksil)-2,4-dimetil-n-((6-metil-4-(metiltio)-2-okso-1,2-dihidropiridin-3-il)metil)benzo[d][1,3]dioksol-5-karboksamida | |
| JP2007532560A5 (https=) | ||
| RU2007141198A (ru) | Кристаллическая форма малеата азенапина | |
| RU2007110026A (ru) | ПОЛИМОРФНЫЕ И АМОРФНАЯ ФОРМЫ ФОСФАТНОЙ СОЛИ 8-ФТОР-2-{4-[(МЕТИЛАМИНО)МЕТИЛ]ФЕНИЛ}-1,3,4,5-ТЕТРАГИДРО-6Н-АЗЕПИНО[5.4.3-cd]ИНДОЛ-6-ОНА | |
| JP2013520424A5 (https=) | ||
| RU2598606C3 (ru) | Кристаллическая тозилатная соль (8s,9r)-5-фтор-8-(4-фторфенил)-9-(1-метил-1н-1,2,4-триазол-5-ил)-8-9-дигидро-2н-пиридо[4,3,2-de]фталазин-3(7н)-она | |
| JP2022037040A5 (https=) | ||
| IL167168A (en) | Indoline compound in crystalline form for use in oral solid medicament and such oral solid medicament for treating dysuria | |
| HRP20120066T1 (hr) | Kalijeva sol inhibitora hiv integraze | |
| RU2014110399A (ru) | Кристаллические формы вгс протеазного ингибитора | |
| RU2008120338A (ru) | Полиморфы с-met/hgfr ингибитора | |
| JP2021517111A5 (https=) | ||
| HRP20170540T1 (hr) | Spojevi dimetilbenzojeve kiseline, korisni u liječenju upalnih stanja | |
| CY1107913T1 (el) | Πολυμορφικες και αλλες κρυσταλλικες μορφες cis-ftc | |
| JP2017532279A5 (https=) | ||
| JP2005523933A5 (https=) | ||
| JP2006249089A5 (https=) |