JP2005511538A5 - - Google Patents
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- JP2005511538A5 JP2005511538A5 JP2003536265A JP2003536265A JP2005511538A5 JP 2005511538 A5 JP2005511538 A5 JP 2005511538A5 JP 2003536265 A JP2003536265 A JP 2003536265A JP 2003536265 A JP2003536265 A JP 2003536265A JP 2005511538 A5 JP2005511538 A5 JP 2005511538A5
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- JP
- Japan
- Prior art keywords
- isomer
- mixture
- day
- isomeric
- administered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34620101P | 2001-10-19 | 2001-10-19 | |
| PCT/CA2002/001560 WO2003033527A2 (en) | 2001-10-19 | 2002-10-17 | Cyclosporine analogue mixtures and their use as immunomodulating agents |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009140608A Division JP5272140B2 (ja) | 2001-10-19 | 2009-06-11 | シクロスポリン類似体混合物及びそれらの免疫調節剤としての使用 |
| JP2010151859A Division JP2011006417A (ja) | 2001-10-19 | 2010-07-02 | シクロスポリン類似体混合物及びそれらの免疫調整剤としての使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005511538A JP2005511538A (ja) | 2005-04-28 |
| JP2005511538A5 true JP2005511538A5 (https=) | 2006-01-12 |
Family
ID=23358378
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003536265A Withdrawn JP2005511538A (ja) | 2001-10-19 | 2002-10-17 | シクロスポリン類似体混合物及びそれらの免疫調節剤としての使用 |
| JP2009140608A Expired - Lifetime JP5272140B2 (ja) | 2001-10-19 | 2009-06-11 | シクロスポリン類似体混合物及びそれらの免疫調節剤としての使用 |
| JP2010151859A Pending JP2011006417A (ja) | 2001-10-19 | 2010-07-02 | シクロスポリン類似体混合物及びそれらの免疫調整剤としての使用 |
| JP2013017448A Pending JP2013136597A (ja) | 2001-10-19 | 2013-01-31 | シクロスポリン類似体混合物及びそれらの免疫調整剤としての使用 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009140608A Expired - Lifetime JP5272140B2 (ja) | 2001-10-19 | 2009-06-11 | シクロスポリン類似体混合物及びそれらの免疫調節剤としての使用 |
| JP2010151859A Pending JP2011006417A (ja) | 2001-10-19 | 2010-07-02 | シクロスポリン類似体混合物及びそれらの免疫調整剤としての使用 |
| JP2013017448A Pending JP2013136597A (ja) | 2001-10-19 | 2013-01-31 | シクロスポリン類似体混合物及びそれらの免疫調整剤としての使用 |
Country Status (38)
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7141648B2 (en) | 2001-10-19 | 2006-11-28 | Isotechnika Inc. | Synthesis of cyclosporin analogs |
| EP1816138A1 (en) * | 2001-10-19 | 2007-08-08 | Isotechnika,Inc. | Cyclosporine analogue mixtures and their use as immunomodulating agents |
| EP1603512A2 (en) | 2003-03-17 | 2005-12-14 | Albany Molecular Research, Inc. | Novel cyclosporins |
| TW200505946A (en) * | 2003-04-08 | 2005-02-16 | Hoffmann La Roche | Process for preparation of cyclosporin a analog |
| US7378391B2 (en) | 2004-09-29 | 2008-05-27 | Amr Technology, Inc. | Cyclosporin alkyne analogues and their pharmaceutical uses |
| WO2006039164A2 (en) | 2004-09-29 | 2006-04-13 | Amr Technology, Inc. | Novel cyclosporin analogues and their pharmaceutical uses |
| WO2006041631A2 (en) | 2004-10-06 | 2006-04-20 | Amr Technology, Inc. | Novel cyclosporin alkynes and their utility as pharmaceutical agents |
| JP2008524122A (ja) * | 2004-12-17 | 2008-07-10 | イソテクニカ インコーポレーテッド | シクロスポリン類似体の代謝体 |
| KR101273681B1 (ko) * | 2005-10-26 | 2013-06-25 | 아스텔라스세이야쿠 가부시키가이샤 | 신규 시클릭 펩티드 화합물 |
| US7696165B2 (en) | 2006-03-28 | 2010-04-13 | Albany Molecular Research, Inc. | Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders |
| US7696166B2 (en) | 2006-03-28 | 2010-04-13 | Albany Molecular Research, Inc. | Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders |
| AU2008250254B2 (en) * | 2007-05-02 | 2012-08-16 | Astellas Pharma Inc. | New cyclic peptide compounds |
| ES2667945T3 (es) | 2007-10-08 | 2018-05-16 | Aurinia Pharmaceuticals Inc. | Composiciones oftálmicas que comprenden inhibidores de calcineurina o Inhibidores de mTOR |
| RU2361604C1 (ru) * | 2007-10-29 | 2009-07-20 | Федеральное агентство по высокотехнологичной медицинской помощи Федеральное государственное учреждение "Уральский научно-исследовательский институт дерматовенерологии и иммунопатологии" (ФГУ УрНИИДВиИ Росмедтехнологий) | Способ лечения атопического дерматита |
| EP2440185B1 (en) | 2009-06-09 | 2015-04-08 | Aurinia Pharmaceuticals Inc. | Topical drug delivery systems for ophthalmic use |
| GB0912584D0 (en) * | 2009-07-20 | 2009-08-26 | Ucl Business Plc | Cyclosporin conjugates |
| WO2012079172A1 (en) | 2010-12-15 | 2012-06-21 | Isotechnika Pharma Inc. | Cyclosporine analogue molecules modified at amino acid 1 and 3 |
| GB201222455D0 (en) | 2012-12-13 | 2013-01-30 | Perioc Ltd | Novel pharmaceutical formulations and their use in the treatment of periodontaldisease |
| JP2020510249A (ja) * | 2016-11-30 | 2020-04-02 | シュレーディンガー インコーポレイテッドＳｃｈｒｏｄｉｎｇｅｒ，Ｉｎｃ． | 化学の遷移状態を計算するためのグラフィカルユーザインタフェース |
| US10610104B2 (en) | 2016-12-07 | 2020-04-07 | Progenity, Inc. | Gastrointestinal tract detection methods, devices and systems |
| WO2018106928A1 (en) | 2016-12-08 | 2018-06-14 | Contravir Pharmaceuticals, Inc. | Treatment and prevention of hbv diseases by cyclosporine analogue molecules modified at amino acides 1 and 3 |
| EP3554346B1 (en) | 2016-12-14 | 2024-01-31 | Biora Therapeutics, Inc. | Treatment of a disease of the gastrointestinal tract with an immunosuppressant |
| US10286036B2 (en) * | 2017-05-12 | 2019-05-14 | Aurinia Pharmaceuticals Inc. | Protocol for treatment of lupus nephritis |
| US20190224275A1 (en) | 2017-05-12 | 2019-07-25 | Aurinia Pharmaceuticals Inc. | Protocol for treatment of lupus nephritis |
| WO2019246312A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
| IL296586B1 (en) | 2020-03-26 | 2026-04-01 | Farsight Medical Tech Shanghai Co Ltd | Cyclophilin inhibitors and their uses |
| EP4201952A1 (en) | 2021-12-21 | 2023-06-28 | Curia Spain, S.A.U. | Process for the controlled synthesis of voclosporin |
| WO2024052941A1 (en) * | 2022-09-09 | 2024-03-14 | Dr. Reddy's Laboratories Limited | Improved process for the preparation of voclosporin |
| IT202300001116A1 (it) * | 2023-01-25 | 2024-07-25 | Indena Spa | Processo per la preparazione di un intermedio utile per la sintesi di voclosporina |
| IT202300001056A1 (it) * | 2023-01-25 | 2024-07-25 | Procos Spa | Nuovo processo per la preparazione di voclosporina amorfa |
| WO2025119925A1 (en) | 2023-12-05 | 2025-06-12 | Medichem, S.A. | Process for preparing voclosporin |
| IT202300028041A1 (it) * | 2023-12-27 | 2025-06-27 | Indena Spa | Processo per la preparazione di voclosporina |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4278545A (en) * | 1979-09-12 | 1981-07-14 | The Bendix Corporation | Apparatus for separating solids and liquid components |
| CH670644A5 (https=) * | 1986-12-18 | 1989-06-30 | Lonza Ag | |
| US5162540A (en) * | 1986-12-18 | 1992-11-10 | Lonza Ltd. | Process for the production of (+) biotin |
| ES2059558T3 (es) * | 1987-06-17 | 1994-11-16 | Sandoz Ag | Ciclosporins y su uso como productos farmaceuticos. |
| US5972630A (en) * | 1991-08-19 | 1999-10-26 | Dade Behring Marburg Gmbh | Homogeneous immunoassays using enzyme inhibitors |
| GB9204466D0 (en) * | 1992-03-02 | 1992-04-15 | Sandoz Ltd | Improvements in or relating to organic compounds |
| US5962019A (en) * | 1995-08-25 | 1999-10-05 | Sangstat Medical Corporation | Oral cyclosporin formulations |
| US5750510A (en) * | 1997-04-04 | 1998-05-12 | Abbott Laboratories | 3-descladinose-2,3-anhydroerythromycin derivatives |
| CN1494920A (zh) * | 1996-06-19 | 2004-05-12 | ��˹��ŵ�� | 含有环孢菌素的软胶囊制剂 |
| US5939406A (en) * | 1997-07-21 | 1999-08-17 | Wisconsin Alumni Research Foundation | 18-substituted-19-nor-vitamin D compounds |
| EP0991660B8 (en) * | 1997-10-08 | 2006-04-05 | Isotechnika,Inc. | DEUTERATED and undeuterated CYCLOSPORINE ANALOGS AND THEIR USE AS IMMUNOMODULATING AGENTS |
| EP1816138A1 (en) * | 2001-10-19 | 2007-08-08 | Isotechnika,Inc. | Cyclosporine analogue mixtures and their use as immunomodulating agents |
| US7141648B2 (en) * | 2001-10-19 | 2006-11-28 | Isotechnika Inc. | Synthesis of cyclosporin analogs |
-
2002
- 2002-10-17 EP EP07106871A patent/EP1816138A1/en not_active Withdrawn
- 2002-10-17 CN CNB02820798XA patent/CN100344648C/zh not_active Expired - Lifetime
- 2002-10-17 IL IL16076202A patent/IL160762A0/xx unknown
- 2002-10-17 NZ NZ531945A patent/NZ531945A/en not_active IP Right Cessation
- 2002-10-17 MY MYPI20023885A patent/MY187182A/en unknown
- 2002-10-17 DE DE60227686T patent/DE60227686D1/de not_active Expired - Lifetime
- 2002-10-17 CA CA2727642A patent/CA2727642C/en not_active Expired - Lifetime
- 2002-10-17 WO PCT/CA2002/001560 patent/WO2003033527A2/en not_active Ceased
- 2002-10-17 AU AU2002331510A patent/AU2002331510B2/en not_active Expired
- 2002-10-17 BR BR0213659-7A patent/BR0213659A/pt not_active IP Right Cessation
- 2002-10-17 UY UY27502A patent/UY27502A1/es not_active Application Discontinuation
- 2002-10-17 DK DK02767028T patent/DK1436322T3/da active
- 2002-10-17 MX MXPA04003624A patent/MXPA04003624A/es active IP Right Grant
- 2002-10-17 ES ES02767028T patent/ES2310604T3/es not_active Expired - Lifetime
- 2002-10-17 JP JP2003536265A patent/JP2005511538A/ja not_active Withdrawn
- 2002-10-17 AR ARP020103918A patent/AR036853A1/es not_active Application Discontinuation
- 2002-10-17 EP EP02767028A patent/EP1436322B1/en not_active Expired - Lifetime
- 2002-10-17 PT PT02767028T patent/PT1436322E/pt unknown
- 2002-10-17 PY PY200200225477A patent/PY0225477A/es unknown
- 2002-10-17 KR KR1020047005721A patent/KR100992850B1/ko not_active Expired - Lifetime
- 2002-10-17 SI SI200230742T patent/SI1436322T1/sl unknown
- 2002-10-17 AT AT02767028T patent/ATE401339T1/de active
- 2002-10-17 HR HRP20040353AA patent/HRP20040353B1/hr not_active IP Right Cessation
- 2002-10-17 CA CA2460685A patent/CA2460685C/en not_active Expired - Lifetime
- 2002-10-17 ME MEP-2008-780A patent/ME00487B/me unknown
- 2002-10-17 PL PL370501A patent/PL210697B1/pl unknown
- 2002-10-17 PY PY200200225478A patent/PY0225478A/es unknown
- 2002-10-17 RU RU2004110941/04A patent/RU2337106C2/ru active
-
2004
- 2004-03-05 IL IL160762A patent/IL160762A/en active IP Right Grant
- 2004-03-23 ZA ZA2004/02270A patent/ZA200402270B/en unknown
- 2004-03-26 MA MA27598A patent/MA26337A1/fr unknown
- 2004-04-14 EC EC2004005061A patent/ECSP045061A/es unknown
- 2004-04-14 EC EC2004005060A patent/ECSP045060A/es unknown
- 2004-04-14 EC EC2004005059A patent/ECSP045059A/es unknown
- 2004-04-16 TN TNP2004000069A patent/TNSN04069A1/en unknown
- 2004-04-19 CO CO04035672A patent/CO5570682A2/es not_active Application Discontinuation
- 2004-05-14 NO NO20042029A patent/NO331745B1/no not_active IP Right Cessation
-
2008
- 2008-10-13 CY CY20081101130T patent/CY1108410T1/el unknown
-
2009
- 2009-06-11 JP JP2009140608A patent/JP5272140B2/ja not_active Expired - Lifetime
-
2010
- 2010-07-02 JP JP2010151859A patent/JP2011006417A/ja active Pending
- 2010-12-23 US US12/977,602 patent/US20110092669A1/en not_active Abandoned
-
2013
- 2013-01-31 JP JP2013017448A patent/JP2013136597A/ja active Pending
-
2014
- 2014-03-18 US US14/217,827 patent/US20140288266A1/en not_active Abandoned
-
2022
- 2022-10-14 NL NL301200C patent/NL301200I2/nl unknown
- 2022-10-14 BE BE2022C547C patent/BE2022C547I2/nl unknown
- 2022-10-14 FR FR22C1051C patent/FR22C1051I2/fr active Active
- 2022-10-14 LT LTPA2022521C patent/LTC1436322I2/lt unknown
- 2022-10-14 NO NO2022042C patent/NO2022042I1/no unknown
- 2022-10-14 FI FIC20220041C patent/FIC20220041I1/fi unknown
- 2022-10-14 CY CY2022030C patent/CY2022030I2/el unknown
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