JP2005510556A5 - - Google Patents

Info

Publication number

JP2005510556A5

JP2005510556A5 JP2003547347A JP2003547347A JP2005510556A5 JP 2005510556 A5 JP2005510556 A5 JP 2005510556A5 JP 2003547347 A JP2003547347 A JP 2003547347A JP 2003547347 A JP2003547347 A JP 2003547347A JP 2005510556 A5 JP2005510556 A5 JP 2005510556A5

Authority

JP

Japan

Prior art keywords

group

formula

ester

physiologically acceptable

alkane

Prior art date

2002-11-22

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
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• 150000003839 salts Chemical class 0.000 claims 11
• 150000001875 compounds Chemical class 0.000 claims 10
• 239000003814 drug Substances 0.000 claims 6
• 150000002148 esters Chemical class 0.000 claims 6
• 125000000217 alkyl group Chemical group 0.000 claims 4
• 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 claims 3
• 239000003795 chemical substances by application Substances 0.000 claims 3
• 229910052739 hydrogen Inorganic materials 0.000 claims 3
• 239000001257 hydrogen Substances 0.000 claims 3
• 238000000034 method Methods 0.000 claims 3
• UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 2
• 125000003545 alkoxy group Chemical group 0.000 claims 2
• 201000010099 disease Diseases 0.000 claims 2
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
• 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 2
• 125000005843 halogen group Chemical group 0.000 claims 2
• 125000003651 hexanedioyl group Chemical group C(CCCCC(=O)*)(=O)* 0.000 claims 2
• 238000004519 manufacturing process Methods 0.000 claims 2
• -1 methoxy, ethoxy, propyloxy, butoxy, pentoxy Chemical group 0.000 claims 2
• 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
• BDJRBEYXGGNYIS-UHFFFAOYSA-N nonanedioic acid Chemical compound OC(=O)CCCCCCCC(O)=O BDJRBEYXGGNYIS-UHFFFAOYSA-N 0.000 claims 2
• 238000002360 preparation method Methods 0.000 claims 2
• 125000000008 (C1-C10) alkyl group Chemical group 0.000 claims 1
• 125000006273 (C1-C3) alkyl group Chemical group 0.000 claims 1
• 208000035143 Bacterial infection Diseases 0.000 claims 1
• 208000005440 Basal Cell Neoplasms Diseases 0.000 claims 1
• 206010004146 Basal cell carcinoma Diseases 0.000 claims 1
• 206010017533 Fungal infection Diseases 0.000 claims 1
• 206010020649 Hyperkeratosis Diseases 0.000 claims 1
• 208000001126 Keratosis Diseases 0.000 claims 1
• 208000031888 Mycoses Diseases 0.000 claims 1
• 206010028980 Neoplasm Diseases 0.000 claims 1
• 208000004210 Pressure Ulcer Diseases 0.000 claims 1
• 241001303601 Rosacea Species 0.000 claims 1
• 208000036142 Viral infection Diseases 0.000 claims 1
• 125000003668 acetyloxy group Chemical group [H]C([H])([H])C(=O)O[*] 0.000 claims 1
• 125000002877 alkyl aryl group Chemical group 0.000 claims 1
• 125000005248 alkyl aryloxy group Chemical group 0.000 claims 1
• 125000003710 aryl alkyl group Chemical group 0.000 claims 1
• 125000003118 aryl group Chemical group 0.000 claims 1
• 125000004104 aryloxy group Chemical group 0.000 claims 1
• 125000004429 atom Chemical group 0.000 claims 1
• 229960002255 azelaic acid Drugs 0.000 claims 1
• 230000001580 bacterial effect Effects 0.000 claims 1
• 208000022362 bacterial infectious disease Diseases 0.000 claims 1
• 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 1
• 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1
• 201000011510 cancer Diseases 0.000 claims 1
• 238000004132 cross linking Methods 0.000 claims 1
• 239000003937 drug carrier Substances 0.000 claims 1
• 229940088679 drug related substance Drugs 0.000 claims 1
• 150000002431 hydrogen Chemical class 0.000 claims 1
• 125000004356 hydroxy functional group Chemical group O* 0.000 claims 1
• 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
• 208000000069 hyperpigmentation Diseases 0.000 claims 1
• 230000003810 hyperpigmentation Effects 0.000 claims 1
• RBKMMJSQKNKNEV-RITPCOANSA-N penicillanic acid Chemical compound OC(=O)[C@H]1C(C)(C)S[C@@H]2CC(=O)N21 RBKMMJSQKNKNEV-RITPCOANSA-N 0.000 claims 1
• 125000001147 pentyl group Chemical group C(CCCC)* 0.000 claims 1
• 239000008194 pharmaceutical composition Substances 0.000 claims 1
• 239000000546 pharmaceutical excipient Substances 0.000 claims 1
• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
• 230000002265 prevention Effects 0.000 claims 1
• 230000000069 prophylactic effect Effects 0.000 claims 1
• 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1
• 201000004700 rosacea Diseases 0.000 claims 1
• 208000011117 substance-related disease Diseases 0.000 claims 1
• 125000001273 sulfonato group Chemical group [O-]S(*)(=O)=O 0.000 claims 1
• 150000003457 sulfones Chemical class 0.000 claims 1
• 230000001225 therapeutic effect Effects 0.000 claims 1
• 238000002560 therapeutic procedure Methods 0.000 claims 1
• 230000003612 virological effect Effects 0.000 claims 1
• 230000029663 wound healing Effects 0.000 claims 1