JP2005510323A - 多重スペクトルコード化を用いる共焦点顕微鏡法並びに分光法コード化共焦点顕微鏡法のためのシステム及び装置 - Google Patents
多重スペクトルコード化を用いる共焦点顕微鏡法並びに分光法コード化共焦点顕微鏡法のためのシステム及び装置 Download PDFInfo
- Publication number
- JP2005510323A JP2005510323A JP2003548016A JP2003548016A JP2005510323A JP 2005510323 A JP2005510323 A JP 2005510323A JP 2003548016 A JP2003548016 A JP 2003548016A JP 2003548016 A JP2003548016 A JP 2003548016A JP 2005510323 A JP2005510323 A JP 2005510323A
- Authority
- JP
- Japan
- Prior art keywords
- light
- tissue
- spectrum
- confocal
- probe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00064—Constructional details of the endoscope body
- A61B1/00071—Insertion part of the endoscope body
- A61B1/0008—Insertion part of the endoscope body characterised by distal tip features
- A61B1/00096—Optical elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00163—Optical arrangements
- A61B1/00172—Optical arrangements with means for scanning
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0062—Arrangements for scanning
- A61B5/0068—Confocal scanning
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
- A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
- A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
- A61B5/415—Evaluating particular organs or parts of the immune or lymphatic systems the glands, e.g. tonsils, adenoids or thymus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
- A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
- A61B5/418—Evaluating particular organs or parts of the immune or lymphatic systems lymph vessels, ducts or nodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6852—Catheters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
- G01J3/0208—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using focussing or collimating elements, e.g. lenses or mirrors; performing aberration correction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
- G01J3/0218—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using optical fibers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0291—Housings; Spectrometer accessories; Spatial arrangement of elements, e.g. folded path arrangements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/06—Scanning arrangements arrangements for order-selection
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/12—Generating the spectrum; Monochromators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/12—Generating the spectrum; Monochromators
- G01J3/14—Generating the spectrum; Monochromators using refracting elements, e.g. prisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/12—Generating the spectrum; Monochromators
- G01J3/18—Generating the spectrum; Monochromators using diffraction elements, e.g. grating
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0028—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders specially adapted for specific applications, e.g. for endoscopes, ophthalmoscopes, attachments to conventional microscopes
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0052—Optical details of the image generation
- G02B21/0056—Optical details of the image generation based on optical coherence, e.g. phase-contrast arrangements, interference arrangements
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0052—Optical details of the image generation
- G02B21/0064—Optical details of the image generation multi-spectral or wavelength-selective arrangements, e.g. wavelength fan-out, chromatic profiling
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0052—Optical details of the image generation
- G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B23/00—Telescopes, e.g. binoculars; Periscopes; Instruments for viewing the inside of hollow bodies; Viewfinders; Optical aiming or sighting devices
- G02B23/24—Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes
- G02B23/2407—Optical details
- G02B23/2453—Optical details of the proximal end
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/06—Scanning arrangements arrangements for order-selection
- G01J2003/062—Scanning arrangements arrangements for order-selection motor-driven
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/06—Scanning arrangements arrangements for order-selection
- G01J2003/064—Use of other elements for scan, e.g. mirror, fixed grating
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/06—Scanning arrangements arrangements for order-selection
- G01J2003/064—Use of other elements for scan, e.g. mirror, fixed grating
- G01J2003/065—Use of fibre scan for spectral scan
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/06—Scanning arrangements arrangements for order-selection
- G01J2003/069—Complex motion, e.g. rotation of grating and correcting translation
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Spectroscopy & Molecular Physics (AREA)
- General Physics & Mathematics (AREA)
- Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Optics & Photonics (AREA)
- Radiology & Medical Imaging (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Astronomy & Astrophysics (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Microscoopes, Condenser (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Instruments For Viewing The Inside Of Hollow Bodies (AREA)
- Endoscopes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/999,182 US6831781B2 (en) | 1998-02-26 | 2001-11-29 | Confocal microscopy with multi-spectral encoding and system and apparatus for spectroscopically encoded confocal microscopy |
| PCT/US2002/038335 WO2003046636A1 (en) | 2001-11-29 | 2002-11-27 | Confocal microscopy with multi-spectral encoding and system and apparatus for spectroscopically encoded confocal microscopy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009294737A Division JP2010107519A (ja) | 2001-11-29 | 2009-12-25 | 多重スペクトルコード化を用いる共焦点顕微鏡法並びに分光法コード化共焦点顕微鏡法のためのシステム及び装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005510323A true JP2005510323A (ja) | 2005-04-21 |
| JP2005510323A5 JP2005510323A5 (https=) | 2006-01-19 |
Family
ID=25545995
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003548016A Pending JP2005510323A (ja) | 2001-11-29 | 2002-11-27 | 多重スペクトルコード化を用いる共焦点顕微鏡法並びに分光法コード化共焦点顕微鏡法のためのシステム及び装置 |
| JP2009294737A Pending JP2010107519A (ja) | 2001-11-29 | 2009-12-25 | 多重スペクトルコード化を用いる共焦点顕微鏡法並びに分光法コード化共焦点顕微鏡法のためのシステム及び装置 |
| JP2012231709A Pending JP2013056165A (ja) | 2001-11-29 | 2012-10-19 | 多重スペクトルコード化を用いる共焦点顕微鏡法並びに分光法コード化共焦点顕微鏡法のためのシステム及び装置 |
| JP2015027425A Expired - Fee Related JP6098953B2 (ja) | 2001-11-29 | 2015-02-16 | 多重スペクトルコード化を用いる共焦点顕微鏡法並びに分光法コード化共焦点顕微鏡法のためのシステム及び装置 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009294737A Pending JP2010107519A (ja) | 2001-11-29 | 2009-12-25 | 多重スペクトルコード化を用いる共焦点顕微鏡法並びに分光法コード化共焦点顕微鏡法のためのシステム及び装置 |
| JP2012231709A Pending JP2013056165A (ja) | 2001-11-29 | 2012-10-19 | 多重スペクトルコード化を用いる共焦点顕微鏡法並びに分光法コード化共焦点顕微鏡法のためのシステム及び装置 |
| JP2015027425A Expired - Fee Related JP6098953B2 (ja) | 2001-11-29 | 2015-02-16 | 多重スペクトルコード化を用いる共焦点顕微鏡法並びに分光法コード化共焦点顕微鏡法のためのシステム及び装置 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US6831781B2 (https=) |
| EP (1) | EP1461654A4 (https=) |
| JP (4) | JP2005510323A (https=) |
| AU (1) | AU2002351184A1 (https=) |
| WO (1) | WO2003046636A1 (https=) |
Cited By (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008541891A (ja) * | 2005-05-31 | 2008-11-27 | ダブリュ・オー・エム・ワールド・オブ・メディスン・アー・ゲー | 組織を視覚的に特徴づけるための方法および装置 |
| JP2012515576A (ja) * | 2009-01-20 | 2012-07-12 | ザ ジェネラル ホスピタル コーポレイション | 内視鏡生検装置、システム、及び方法 |
| JP2013507189A (ja) * | 2009-10-06 | 2013-03-04 | ザ ジェネラル ホスピタル コーポレーション | 好酸球を含めた特定の細胞を撮像するための装置および方法 |
| JP2014064935A (ja) * | 2008-07-14 | 2014-04-17 | General Hospital Corp | カラー内視鏡検査のための装置および方法 |
| JP2014139822A (ja) * | 2008-07-24 | 2014-07-31 | Regents Of The Univ Of California:The | ディスパーシブフーリエ変換イメージングの装置および方法 |
| US9629528B2 (en) | 2012-03-30 | 2017-04-25 | The General Hospital Corporation | Imaging system, method and distal attachment for multidirectional field of view endoscopy |
| US9642531B2 (en) | 2010-03-05 | 2017-05-09 | The General Hospital Corporation | Systems, methods and computer-accessible medium which provide microscopic images of at least one anatomical structure at a particular resolution |
| USRE46412E1 (en) | 2006-02-24 | 2017-05-23 | The General Hospital Corporation | Methods and systems for performing angle-resolved Fourier-domain optical coherence tomography |
| US9664615B2 (en) | 2004-07-02 | 2017-05-30 | The General Hospital Corporation | Imaging system and related techniques |
| US9733460B2 (en) | 2014-01-08 | 2017-08-15 | The General Hospital Corporation | Method and apparatus for microscopic imaging |
| US9763623B2 (en) | 2004-08-24 | 2017-09-19 | The General Hospital Corporation | Method and apparatus for imaging of vessel segments |
| US9784681B2 (en) | 2013-05-13 | 2017-10-10 | The General Hospital Corporation | System and method for efficient detection of the phase and amplitude of a periodic modulation associated with self-interfering fluorescence |
| US9795301B2 (en) | 2010-05-25 | 2017-10-24 | The General Hospital Corporation | Apparatus, systems, methods and computer-accessible medium for spectral analysis of optical coherence tomography images |
| US9951269B2 (en) | 2010-05-03 | 2018-04-24 | The General Hospital Corporation | Apparatus, method and system for generating optical radiation from biological gain media |
| US9968261B2 (en) | 2013-01-28 | 2018-05-15 | The General Hospital Corporation | Apparatus and method for providing diffuse spectroscopy co-registered with optical frequency domain imaging |
| US9968245B2 (en) | 2006-10-19 | 2018-05-15 | The General Hospital Corporation | Apparatus and method for obtaining and providing imaging information associated with at least one portion of a sample, and effecting such portion(s) |
| US10058250B2 (en) | 2013-07-26 | 2018-08-28 | The General Hospital Corporation | System, apparatus and method for utilizing optical dispersion for fourier-domain optical coherence tomography |
| US10117576B2 (en) | 2013-07-19 | 2018-11-06 | The General Hospital Corporation | System, method and computer accessible medium for determining eye motion by imaging retina and providing feedback for acquisition of signals from the retina |
| US10228556B2 (en) | 2014-04-04 | 2019-03-12 | The General Hospital Corporation | Apparatus and method for controlling propagation and/or transmission of electromagnetic radiation in flexible waveguide(s) |
| US10285568B2 (en) | 2010-06-03 | 2019-05-14 | The General Hospital Corporation | Apparatus and method for devices for imaging structures in or at one or more luminal organs |
| US10426548B2 (en) | 2006-02-01 | 2019-10-01 | The General Hosppital Corporation | Methods and systems for providing electromagnetic radiation to at least one portion of a sample using conformal laser therapy procedures |
| US10478072B2 (en) | 2013-03-15 | 2019-11-19 | The General Hospital Corporation | Methods and system for characterizing an object |
| US10736494B2 (en) | 2014-01-31 | 2020-08-11 | The General Hospital Corporation | System and method for facilitating manual and/or automatic volumetric imaging with real-time tension or force feedback using a tethered imaging device |
| US10893806B2 (en) | 2013-01-29 | 2021-01-19 | The General Hospital Corporation | Apparatus, systems and methods for providing information regarding the aortic valve |
| US10912462B2 (en) | 2014-07-25 | 2021-02-09 | The General Hospital Corporation | Apparatus, devices and methods for in vivo imaging and diagnosis |
| US10939825B2 (en) | 2010-05-25 | 2021-03-09 | The General Hospital Corporation | Systems, devices, methods, apparatus and computer-accessible media for providing optical imaging of structures and compositions |
| US11179028B2 (en) | 2013-02-01 | 2021-11-23 | The General Hospital Corporation | Objective lens arrangement for confocal endomicroscopy |
| US11452433B2 (en) | 2013-07-19 | 2022-09-27 | The General Hospital Corporation | Imaging apparatus and method which utilizes multidirectional field of view endoscopy |
| US11490826B2 (en) | 2009-07-14 | 2022-11-08 | The General Hospital Corporation | Apparatus, systems and methods for measuring flow and pressure within a vessel |
| US11490797B2 (en) | 2012-05-21 | 2022-11-08 | The General Hospital Corporation | Apparatus, device and method for capsule microscopy |
| US12611089B2 (en) | 2022-09-02 | 2026-04-28 | The General Hospital Corporation | Imaging apparatus and method which utilizes multidirectional field of view endoscopy |
Families Citing this family (141)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60141090D1 (de) * | 2000-10-30 | 2010-03-04 | Gen Hospital Corp | Optische systeme zur gewebeanalyse |
| US9295391B1 (en) | 2000-11-10 | 2016-03-29 | The General Hospital Corporation | Spectrally encoded miniature endoscopic imaging probe |
| EP2333521B1 (en) | 2001-04-30 | 2019-12-04 | The General Hospital Corporation | Method and apparatus for improving image clarity and sensitivity in optical coherence tomography using dynamic feedback to control focal properties and coherence gating |
| WO2002088705A2 (en) | 2001-05-01 | 2002-11-07 | The General Hospital Corporation | Method and apparatus for determination of atherosclerotic plaque type by measurement of tissue optical properties |
| US6980299B1 (en) | 2001-10-16 | 2005-12-27 | General Hospital Corporation | Systems and methods for imaging a sample |
| EP2327954A1 (en) * | 2002-01-11 | 2011-06-01 | The General Hospital Corporation | Apparatus for OCT imaging with axial line focus for improved resolution and depth of field |
| US7355716B2 (en) | 2002-01-24 | 2008-04-08 | The General Hospital Corporation | Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands |
| NZ535953A (en) | 2002-04-15 | 2007-02-23 | Epos Technologies Ltd | Method and system for obtaining positioning data |
| US8054468B2 (en) | 2003-01-24 | 2011-11-08 | The General Hospital Corporation | Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands |
| AU2004206998B2 (en) | 2003-01-24 | 2009-12-17 | The General Hospital Corporation | System and method for identifying tissue using low-coherence interferometry |
| JP4338412B2 (ja) * | 2003-02-24 | 2009-10-07 | Hoya株式会社 | 共焦点プローブおよび共焦点顕微鏡 |
| CA2519937C (en) | 2003-03-31 | 2012-11-20 | Guillermo J. Tearney | Speckle reduction in optical coherence tomography by path length encoded angular compounding |
| EP2280260B1 (en) | 2003-06-06 | 2017-03-08 | The General Hospital Corporation | Process and apparatus for a wavelength tuned light source |
| US7030383B2 (en) * | 2003-08-04 | 2006-04-18 | Cadent Ltd. | Speckle reduction method and apparatus |
| JP5567246B2 (ja) | 2003-10-27 | 2014-08-06 | ザ ジェネラル ホスピタル コーポレイション | 周波数ドメイン干渉測定を利用して光学撮像を実行する方法および装置 |
| JP5214883B2 (ja) | 2003-11-28 | 2013-06-19 | ザ ジェネラル ホスピタル コーポレイション | 三次元分光的符号化撮像のための方法と装置 |
| FR2864438B1 (fr) * | 2003-12-31 | 2006-11-17 | Mauna Kea Technologies | Tete optique miniature a balayage integre pour la realisation d'une image confocale homogene, et systeme d'imagerie confocale utilisant ladite tete |
| JP5243025B2 (ja) | 2004-05-17 | 2013-07-24 | エポス ディベロップメント リミテッド | 音響測位システムのための頑健な音響同期シグナリング |
| WO2005117534A2 (en) | 2004-05-29 | 2005-12-15 | The General Hospital Corporation | Process, system and software arrangement for a chromatic dispersion compensation using reflective layers in optical coherence tomography (oct) imaging |
| US7852551B2 (en) * | 2004-06-14 | 2010-12-14 | Olympus Corporation | Optical-scanning microscope examination apparatus |
| EP1782020B1 (en) | 2004-08-06 | 2012-10-03 | The General Hospital Corporation | Process, system and software arrangement for determining at least one location in a sample using an optical coherence tomography |
| WO2006024014A2 (en) | 2004-08-24 | 2006-03-02 | The General Hospital Corporation | Process, system and software arrangement for measuring a mechanical strain and elastic properties of a sample |
| JP5215664B2 (ja) | 2004-09-10 | 2013-06-19 | ザ ジェネラル ホスピタル コーポレイション | 光学コヒーレンス撮像のシステムおよび方法 |
| US8391959B2 (en) | 2004-09-29 | 2013-03-05 | Tel Hashomer Medical Research Infrastructure And Services Ltd. | Composition for improving efficiency of drug delivery |
| JP4997112B2 (ja) | 2004-09-29 | 2012-08-08 | ザ ジェネラル ホスピタル コーポレイション | 少なくとも1つの電磁放射を伝送させるための装置およびその製造方法 |
| US9161820B2 (en) | 2004-10-28 | 2015-10-20 | Nico Corporation | Surgical access assembly and method of using same |
| JP5623692B2 (ja) | 2004-11-02 | 2014-11-12 | ザ ジェネラル ホスピタル コーポレイション | 試料の画像形成のための光ファイバ回転装置、光学システム及び方法 |
| EP2278265A3 (en) | 2004-11-24 | 2011-06-29 | The General Hospital Corporation | Common-Path Interferometer for Endoscopic OCT |
| US8922781B2 (en) | 2004-11-29 | 2014-12-30 | The General Hospital Corporation | Arrangements, devices, endoscopes, catheters and methods for performing optical imaging by simultaneously illuminating and detecting multiple points on a sample |
| CN100516841C (zh) * | 2004-12-09 | 2009-07-22 | 暨南大学 | 一种可产生明场或宽场荧光光切片的方法 |
| US7367944B2 (en) | 2004-12-13 | 2008-05-06 | Tel Hashomer Medical Research Infrastructure And Services Ltd. | Method and system for monitoring ablation of tissues |
| CN101180601B (zh) | 2005-03-23 | 2014-09-17 | 高通股份有限公司 | 数字笔和数字笔系统 |
| EP2085929A1 (en) | 2005-04-28 | 2009-08-05 | The General Hospital Corporation | Evaluating optical coherence tomography information for an anatomical structure |
| WO2006130797A2 (en) * | 2005-05-31 | 2006-12-07 | The General Hospital Corporation | Spectral encoding heterodyne interferometry techniques for imaging |
| EP1889037A2 (en) | 2005-06-01 | 2008-02-20 | The General Hospital Corporation | Apparatus, method and system for performing phase-resolved optical frequency domain imaging |
| US7909817B2 (en) * | 2005-06-08 | 2011-03-22 | Innovaquartz, Inc. (AMS Research Corporation) | Lateral laser fiber for high average power and peak pulse energy |
| GB0515758D0 (en) * | 2005-07-30 | 2005-09-07 | Univ Hospital Of North Staffor | Improvements in and relating to optical coherence tomography |
| ATE484727T1 (de) | 2005-08-09 | 2010-10-15 | Gen Hospital Corp | Gerät und verfahren zur durchführung von polarisationsbasierter quadraturdemodulation bei optischer kohärenztomographie |
| AU2006299659A1 (en) | 2005-09-29 | 2007-04-12 | General Hospital Corporation | Method and apparatus for method for viewing and analyzing of one or more biological samples with progressively increasing resolutions |
| US7889348B2 (en) | 2005-10-14 | 2011-02-15 | The General Hospital Corporation | Arrangements and methods for facilitating photoluminescence imaging |
| EP1971848B1 (en) * | 2006-01-10 | 2019-12-04 | The General Hospital Corporation | Systems and methods for generating data based on one or more spectrally-encoded endoscopy techniques |
| ES2847854T3 (es) | 2006-01-19 | 2021-08-04 | Massachusetts Gen Hospital | Catéter de globo de obtención de imágenes |
| US8145018B2 (en) | 2006-01-19 | 2012-03-27 | The General Hospital Corporation | Apparatus for obtaining information for a structure using spectrally-encoded endoscopy techniques and methods for producing one or more optical arrangements |
| US7538859B2 (en) | 2006-02-01 | 2009-05-26 | The General Hospital Corporation | Methods and systems for monitoring and obtaining information of at least one portion of a sample using conformal laser therapy procedures, and providing electromagnetic radiation thereto |
| JP2009537024A (ja) | 2006-02-01 | 2009-10-22 | ザ ジェネラル ホスピタル コーポレイション | 少なくとも一つのファイバの少なくとも二つの部位の少なくとも一つを制御する装置 |
| EP3143926B1 (en) | 2006-02-08 | 2020-07-01 | The General Hospital Corporation | Methods, arrangements and systems for obtaining information associated with an anatomical sample using optical microscopy |
| US7742173B2 (en) | 2006-04-05 | 2010-06-22 | The General Hospital Corporation | Methods, arrangements and systems for polarization-sensitive optical frequency domain imaging of a sample |
| EP3150110B1 (en) | 2006-05-10 | 2020-09-02 | The General Hospital Corporation | Processes, arrangements and systems for providing frequency domain imaging of a sample |
| US7782464B2 (en) | 2006-05-12 | 2010-08-24 | The General Hospital Corporation | Processes, arrangements and systems for providing a fiber layer thickness map based on optical coherence tomography images |
| EP2054712B1 (en) | 2006-08-25 | 2015-10-07 | The General Hospital Corporation | Apparatus and methods for enhancing optical coherence tomography imaging using volumetric filtering techniques |
| WO2008089406A2 (en) | 2007-01-19 | 2008-07-24 | The General Hospital Corporation | Apparatus and method for simultaneous inspection at different depths based on the principle of frequency domain optical coherence tomography |
| EP2104968A1 (en) | 2007-01-19 | 2009-09-30 | The General Hospital Corporation | Rotating disk reflection for fast wavelength scanning of dispersed broadband light |
| AU2008224542B2 (en) | 2007-03-14 | 2012-01-19 | Qualcomm Incorporated | MEMS microphone |
| EP2602651A3 (en) | 2007-03-23 | 2014-08-27 | The General Hospital Corporation | Methods, arrangements and apparatus for utilizing a wavelength-swept laser using angular scanning and dispersion procedures |
| WO2008121844A1 (en) | 2007-03-30 | 2008-10-09 | The General Hospital Corporation | System and method providing intracoronary laser speckle imaging for the detection of vulnerable plaque |
| US8045177B2 (en) | 2007-04-17 | 2011-10-25 | The General Hospital Corporation | Apparatus and methods for measuring vibrations using spectrally-encoded endoscopy |
| WO2008137637A2 (en) | 2007-05-04 | 2008-11-13 | The General Hospital Corporation | Methods, arrangements and systems for obtaining information associated with a sample using brillouin microscopy |
| US9181555B2 (en) * | 2007-07-23 | 2015-11-10 | Ramot At Tel-Aviv University Ltd. | Photocatalytic hydrogen production and polypeptides capable of same |
| EP2173254A2 (en) | 2007-07-31 | 2010-04-14 | The General Hospital Corporation | Systems and methods for providing beam scan patterns for high speed doppler optical frequency domain imaging |
| US8040608B2 (en) | 2007-08-31 | 2011-10-18 | The General Hospital Corporation | System and method for self-interference fluorescence microscopy, and computer-accessible medium associated therewith |
| JP5643101B2 (ja) | 2007-10-25 | 2014-12-17 | ワシントン・ユニバーシティWashington University | 散乱媒体の画像化方法、画像化装置及び画像化システム |
| WO2009059034A1 (en) | 2007-10-30 | 2009-05-07 | The General Hospital Corporation | System and method for cladding mode detection |
| US11123047B2 (en) | 2008-01-28 | 2021-09-21 | The General Hospital Corporation | Hybrid systems and methods for multi-modal acquisition of intravascular imaging data and counteracting the effects of signal absorption in blood |
| US9332942B2 (en) | 2008-01-28 | 2016-05-10 | The General Hospital Corporation | Systems, processes and computer-accessible medium for providing hybrid flourescence and optical coherence tomography imaging |
| US7898656B2 (en) | 2008-04-30 | 2011-03-01 | The General Hospital Corporation | Apparatus and method for cross axis parallel spectroscopy |
| EP2274572A4 (en) | 2008-05-07 | 2013-08-28 | Gen Hospital Corp | SYSTEM, METHOD AND COMPUTER MEDIUM FOR TRACKING A VASCULAR MOVEMENT IN A THREE-DIMENSIONAL CORONARTERTERIC MICROSCOPY |
| EP2288948A4 (en) | 2008-06-20 | 2011-12-28 | Gen Hospital Corp | Fused fiber optic coupler arrangement and method for use thereof |
| US9687190B2 (en) | 2008-07-30 | 2017-06-27 | Vanderbilt University | Intra-operative use of fluorescence spectroscopy and applications of same |
| US8440952B2 (en) | 2008-11-18 | 2013-05-14 | The Regents Of The University Of California | Methods for optical amplified imaging using a two-dimensional spectral brush |
| ES2957932T3 (es) | 2008-12-10 | 2024-01-30 | Massachusetts Gen Hospital | Sistemas, aparatos y procedimientos para ampliar el rango de profundidad de imagen de tomografía de coherencia óptica mediante submuestreo óptico |
| US9351705B2 (en) | 2009-01-09 | 2016-05-31 | Washington University | Miniaturized photoacoustic imaging apparatus including a rotatable reflector |
| JP2012515930A (ja) | 2009-01-26 | 2012-07-12 | ザ ジェネラル ホスピタル コーポレーション | 広視野の超解像顕微鏡を提供するためのシステム、方法及びコンピューターがアクセス可能な媒体 |
| CN104134928A (zh) | 2009-02-04 | 2014-11-05 | 通用医疗公司 | 利用高速光学波长调谐源的设备和方法 |
| WO2010105197A2 (en) | 2009-03-12 | 2010-09-16 | The General Hospital Corporation | Non-contact optical system, computer-accessible medium and method for measuring at least one mechanical property of tissue using coherent speckle techniques(s) |
| JP6210682B2 (ja) * | 2009-09-14 | 2017-10-11 | メモリアル スローン−ケタリング キャンサー センター | 低侵襲手術における組織の切開、切除およびアブレーションのためのレーザー・ステアリングおよびフォーカシングを提供する装置、システムおよび方法 |
| WO2011136857A2 (en) * | 2010-01-06 | 2011-11-03 | Trustees Of Boston University | Correlation confocal microscope |
| WO2011127428A2 (en) | 2010-04-09 | 2011-10-13 | Washington University | Quantification of optical absorption coefficients using acoustic spectra in photoacoustic tomography |
| EP4238492A3 (en) | 2010-05-28 | 2023-09-27 | The General Hospital Corporation | Apparatus, systems, methods and computer-accessible medium for analyzing information regarding cardiovascular disease(s) and function(s) |
| JP5541972B2 (ja) * | 2010-06-09 | 2014-07-09 | オリンパス株式会社 | 走査型共焦点顕微鏡 |
| EP2632324A4 (en) | 2010-10-27 | 2015-04-22 | Gen Hospital Corp | DEVICES, SYSTEMS AND METHOD FOR MEASURING BLOOD PRESSURE IN AT LEAST ONE VESSEL |
| US9063074B2 (en) * | 2010-12-30 | 2015-06-23 | Empire Technology Development Llc | Analyzing tissue morphology in three dimensions |
| US8997572B2 (en) | 2011-02-11 | 2015-04-07 | Washington University | Multi-focus optical-resolution photoacoustic microscopy with ultrasonic array detection |
| WO2012149175A1 (en) | 2011-04-29 | 2012-11-01 | The General Hospital Corporation | Means for determining depth-resolved physical and/or optical properties of scattering media |
| JP2014523536A (ja) | 2011-07-19 | 2014-09-11 | ザ ジェネラル ホスピタル コーポレイション | 光コヒーレンストモグラフィーにおいて偏波モード分散補償を提供するためのシステム、方法、装置およびコンピュータアクセス可能な媒体 |
| WO2013029047A1 (en) | 2011-08-25 | 2013-02-28 | The General Hospital Corporation | Methods, systems, arrangements and computer-accessible medium for providing micro-optical coherence tomography procedures |
| US9341783B2 (en) | 2011-10-18 | 2016-05-17 | The General Hospital Corporation | Apparatus and methods for producing and/or providing recirculating optical delay(s) |
| US20140336990A1 (en) * | 2011-11-24 | 2014-11-13 | National University Corporation Tokyo University Of Agriculture And Technology | Measurement device and measurement method |
| JP6227652B2 (ja) | 2012-08-22 | 2017-11-08 | ザ ジェネラル ホスピタル コーポレイション | ソフトリソグラフィを用いてミニチュア内視鏡を製作するためのシステム、方法、およびコンピュータ・アクセス可能媒体 |
| US11020006B2 (en) | 2012-10-18 | 2021-06-01 | California Institute Of Technology | Transcranial photoacoustic/thermoacoustic tomography brain imaging informed by adjunct image data |
| US9562860B1 (en) | 2013-06-19 | 2017-02-07 | Theranos, Inc. | Methods and devices for sample analysis |
| WO2015077355A1 (en) | 2013-11-19 | 2015-05-28 | Washington University | Systems and methods of grueneisen-relaxation photoacoustic microscopy and photoacoustic wavefront shaping |
| TWI533834B (zh) * | 2013-12-10 | 2016-05-21 | Ying-Jie Su | Magnetic manipulation of the surgical lighting device and a hand with a lighting function Assisted system |
| WO2015105850A1 (en) | 2014-01-07 | 2015-07-16 | The General Hospital Corporation | Method and apparatus for recording microscopic images from within a living organism using an implantable device |
| KR101850640B1 (ko) | 2014-01-31 | 2018-04-19 | 캐논 유.에스.에이. 인코포레이티드 | 컬러 내시경을 위한 장치 및 방법 |
| WO2015116951A2 (en) | 2014-01-31 | 2015-08-06 | Canon U.S.A., Inc. | Optical probe, light intensity detection, imaging method and system |
| EP4487773A3 (en) | 2014-01-31 | 2025-01-15 | The General Hospital Corporation | Method and apparatus for performing multidimensional velocity measurements based on amplitude and phase signals in the field of optical interferometry |
| US10130259B2 (en) | 2014-02-05 | 2018-11-20 | British Columbia Cancer Agency Branch | Systems for optical imaging of biological tissues |
| KR101476820B1 (ko) * | 2014-04-07 | 2014-12-29 | 주식회사 썸텍 | 3d 비디오 현미경 장치 |
| US10959712B2 (en) * | 2015-03-10 | 2021-03-30 | The General Hospital Corporation | Apparatus, method and computer-accessible medium for obtaining tissue sample |
| WO2017002535A1 (ja) * | 2015-06-29 | 2017-01-05 | 国立大学法人徳島大学 | 計測装置 |
| WO2017024145A1 (en) | 2015-08-05 | 2017-02-09 | Canon U.S.A., Inc. | Forward and angle view endoscope |
| WO2017024234A1 (en) | 2015-08-05 | 2017-02-09 | Canon U.S.A., Inc. | Endoscope probes and systems, and methods for use therewith |
| US11131860B1 (en) * | 2015-09-14 | 2021-09-28 | Wavefront Research, Inc. | Wide spatial field optical systems |
| WO2017049085A1 (en) | 2015-09-16 | 2017-03-23 | The General Hospital Corporation | Apparatus and methods for mirror tunnel imaging device and for providing pseudo-bessel beams in a miniaturized optical system for imaging |
| US9784619B2 (en) * | 2015-10-13 | 2017-10-10 | Beijing Information Science & Technology University | Fiber grating demodulation system for enhancing spectral resolution of detector array |
| US9869588B2 (en) * | 2015-10-13 | 2018-01-16 | Beijing Information Science & Technology University | Fiber grating demodulation system for enhancing spectral resolution by finely shifting slit |
| US9784618B2 (en) * | 2015-10-14 | 2017-10-10 | Beijing Information Science & Technology University | Fiber grating demodulation system for enhancing spectral resolution by finely rotating light splitting grating |
| US9869587B2 (en) * | 2015-10-14 | 2018-01-16 | Bejing Information Science & Technology University | Fiber grating demodulation system for enhancing spectral resolution by finely shifting linear array detector |
| JP6570427B2 (ja) * | 2015-11-06 | 2019-09-04 | 浜松ホトニクス株式会社 | 画像取得装置、画像取得方法、及び空間光変調ユニット |
| JP6448055B2 (ja) | 2015-11-09 | 2019-01-09 | 富士フイルム株式会社 | 超音波内視鏡及び超音波内視鏡の製造方法 |
| JP6649044B2 (ja) * | 2015-11-10 | 2020-02-19 | 富士フイルム株式会社 | 超音波内視鏡及び超音波内視鏡の製造方法 |
| US10451479B2 (en) * | 2015-11-11 | 2019-10-22 | The Curators Of The University Of Missouri | Multichannel ultra-sensitive optical spectroscopic detection |
| US9869854B2 (en) | 2015-12-16 | 2018-01-16 | Canon U.S.A, Inc. | Endoscopic system |
| WO2017117203A1 (en) | 2015-12-28 | 2017-07-06 | Canon U.S.A., Inc. | Optical probe, light intensity detection, imaging method and system |
| CN119756163A (zh) | 2016-02-12 | 2025-04-04 | 通用医疗公司 | 用于使用光学相干断层成像进行高速和长深度范围成像的装置和方法 |
| WO2017139657A1 (en) | 2016-02-12 | 2017-08-17 | Canon U.S.A., Inc. | Simple monolithic optical element for forward-viewing spectrally encoded endoscopy |
| US10321810B2 (en) | 2016-06-13 | 2019-06-18 | Canon U.S.A., Inc. | Spectrally encoded endoscopic probe having a fixed fiber |
| KR102560803B1 (ko) | 2016-07-05 | 2023-07-31 | 더 제너럴 하스피탈 코포레이션 | 능동적으로 제어되는 광학 이미징 장치를 위한 시스템들 및 방법들 |
| JP2019527576A (ja) | 2016-07-15 | 2019-10-03 | キヤノン ユーエスエイ, インコーポレイテッドCanon U.S.A., Inc | スペクトル符号化プローブ |
| US10401610B2 (en) | 2016-07-15 | 2019-09-03 | Canon Usa, Inc. | Spectrally encoded probe with multiple diffraction orders |
| JP2019534069A (ja) | 2016-09-23 | 2019-11-28 | キヤノン ユーエスエイ, インコーポレイテッドCanon U.S.A., Inc | スペクトル符号化内視鏡検査装置および方法 |
| US10898068B2 (en) | 2016-11-01 | 2021-01-26 | Canon U.S.A., Inc. | Multi-bandwidth spectrally encoded endoscope |
| JP2018094395A (ja) | 2016-11-03 | 2018-06-21 | キヤノン ユーエスエイ, インコーポレイテッドCanon U.S.A., Inc | 診断用スペクトル符号化内視鏡検査装置およびシステム、ならびにこれらと共に使用するための方法 |
| US10222607B2 (en) | 2016-12-14 | 2019-03-05 | Canon U.S.A., Inc. | Three-dimensional endoscope |
| US10989517B2 (en) | 2016-12-22 | 2021-04-27 | ContinUse Biometrics Ltd. | Vibration sensing system with wavelength encoding |
| EP3602003B1 (en) | 2017-03-31 | 2026-04-22 | Life Technologies Corporation | Apparatuses, systems and methods for imaging flow cytometry |
| US11672426B2 (en) | 2017-05-10 | 2023-06-13 | California Institute Of Technology | Snapshot photoacoustic photography using an ergodic relay |
| US10825152B2 (en) | 2017-09-14 | 2020-11-03 | Canon U.S.A., Inc. | Distortion measurement and correction for spectrally encoded endoscopy |
| EP3722787B1 (en) * | 2017-12-07 | 2024-03-27 | Yokogawa Electric Corporation | Spectroscopic analyzer |
| US11530979B2 (en) | 2018-08-14 | 2022-12-20 | California Institute Of Technology | Multifocal photoacoustic microscopy through an ergodic relay |
| WO2020051246A1 (en) | 2018-09-04 | 2020-03-12 | California Institute Of Technology | Enhanced-resolution infrared photoacoustic microscopy and spectroscopy |
| EP3637167B1 (en) * | 2018-10-11 | 2024-12-04 | Baden-Württemberg Stiftung gGmbH | Area scanning confocal microscopy (ascm) |
| US11369280B2 (en) | 2019-03-01 | 2022-06-28 | California Institute Of Technology | Velocity-matched ultrasonic tagging in photoacoustic flowgraphy |
| US11441948B2 (en) * | 2019-03-25 | 2022-09-13 | Mks Technology, Inc. | Multi-dispersive spectrometer |
| JP7413512B2 (ja) | 2019-08-27 | 2024-01-15 | ザ ジェネラル ホスピタル コーポレイション | 高分解能高速カプセル内視鏡のためのシステム及び方法 |
| US11986269B2 (en) | 2019-11-05 | 2024-05-21 | California Institute Of Technology | Spatiotemporal antialiasing in photoacoustic computed tomography |
| EP4337081A4 (en) | 2021-05-14 | 2025-04-16 | Leadoptik Inc. | Methods and apparatus for reconfigurable optical endoscopic catheter |
| US20240350015A1 (en) | 2021-08-16 | 2024-10-24 | Spectrawave, Inc. | Multi modality rotary optical systems and methods of their use |
| US12504363B2 (en) | 2021-08-17 | 2025-12-23 | California Institute Of Technology | Three-dimensional contoured scanning photoacoustic imaging and virtual staining |
| US12593986B2 (en) | 2023-04-12 | 2026-04-07 | California Institute Of Technology | Transmission mode-photoacoustic tomography of the human brain through an acoustic window |
| FR3151410A1 (fr) * | 2023-07-20 | 2025-01-24 | Framatome | Dispositif de balayage endoscopique sans déplacement mécanique, ensemble et procédé associés |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2626383B1 (fr) | 1988-01-27 | 1991-10-25 | Commissariat Energie Atomique | Procede de microscopie optique confocale a balayage et en profondeur de champ etendue et dispositifs pour la mise en oeuvre du procede |
| GB9015793D0 (en) | 1990-07-18 | 1990-09-05 | Medical Res Council | Confocal scanning optical microscope |
| US5127730A (en) | 1990-08-10 | 1992-07-07 | Regents Of The University Of Minnesota | Multi-color laser scanning confocal imaging system |
| US6111645A (en) | 1991-04-29 | 2000-08-29 | Massachusetts Institute Of Technology | Grating based phase control optical delay line |
| US5248876A (en) | 1992-04-21 | 1993-09-28 | International Business Machines Corporation | Tandem linear scanning confocal imaging system with focal volumes at different heights |
| US5698397A (en) | 1995-06-07 | 1997-12-16 | Sri International | Up-converting reporters for biological and other assays using laser excitation techniques |
| DE69325783T2 (de) * | 1992-12-11 | 1999-11-18 | Raytheon Co., El Segundo | Achromatisches und apochromatisches Prismenelement aus Prisma und Gittern |
| EP0602992B1 (en) * | 1992-12-18 | 1999-03-03 | Raytheon Company | Grating-prism combination |
| US5450203A (en) | 1993-12-22 | 1995-09-12 | Electroglas, Inc. | Method and apparatus for determining an objects position, topography and for imaging |
| DE4411017C2 (de) | 1994-03-30 | 1995-06-08 | Alexander Dr Knuettel | Optische stationäre spektroskopische Bildgebung in stark streuenden Objekten durch spezielle Lichtfokussierung und Signal-Detektion von Licht unterschiedlicher Wellenlängen |
| US5459325A (en) | 1994-07-19 | 1995-10-17 | Molecular Dynamics, Inc. | High-speed fluorescence scanner |
| US5600486A (en) | 1995-01-30 | 1997-02-04 | Lockheed Missiles And Space Company, Inc. | Color separation microlens |
| US5526338A (en) | 1995-03-10 | 1996-06-11 | Yeda Research & Development Co. Ltd. | Method and apparatus for storage and retrieval with multilayer optical disks |
| US5785651A (en) | 1995-06-07 | 1998-07-28 | Keravision, Inc. | Distance measuring confocal microscope |
| US5742419A (en) * | 1995-11-07 | 1998-04-21 | The Board Of Trustees Of The Leland Stanford Junior Universtiy | Miniature scanning confocal microscope |
| DE19640495C2 (de) * | 1996-10-01 | 1999-12-16 | Leica Microsystems | Vorrichtung zur konfokalen Oberflächenvermessung |
| JP2001515382A (ja) * | 1997-03-06 | 2001-09-18 | マサチューセッツ インスティチュート オブ テクノロジー | 生体組織の光学走査用機器 |
| US5887009A (en) * | 1997-05-22 | 1999-03-23 | Optical Biopsy Technologies, Inc. | Confocal optical scanning system employing a fiber laser |
| EP2267507A3 (en) * | 1998-02-26 | 2011-08-17 | The General Hospital Corporation | Confocal microscopy with multi-spectral encoding |
| RU2148378C1 (ru) * | 1998-03-06 | 2000-05-10 | Геликонов Валентин Михайлович | Устройство для оптической когерентной томографии, оптоволоконное сканирующее устройство и способ диагностики биоткани in vivo |
| US6166373A (en) | 1998-07-21 | 2000-12-26 | The Institute For Technology Development | Focal plane scanner with reciprocating spatial window |
| FR2783330B1 (fr) * | 1998-09-15 | 2002-06-14 | Assist Publ Hopitaux De Paris | Dispositif d'observation de l'interieur d'un corps produisant une qualite d'observation perfectionnee |
| JP2000121961A (ja) * | 1998-10-13 | 2000-04-28 | Olympus Optical Co Ltd | 共焦点光走査プローブシステム |
| JP2000292703A (ja) * | 1999-04-02 | 2000-10-20 | Olympus Optical Co Ltd | 共焦点光学装置 |
| JP2001174744A (ja) * | 1999-10-06 | 2001-06-29 | Olympus Optical Co Ltd | 光走査プローブ装置 |
| JP2001149305A (ja) * | 1999-11-29 | 2001-06-05 | Olympus Optical Co Ltd | 光走査プローブ装置 |
| JP2001327460A (ja) * | 2000-05-18 | 2001-11-27 | Olympus Optical Co Ltd | 内視鏡装置 |
| JP4460117B2 (ja) | 2000-06-29 | 2010-05-12 | 独立行政法人理化学研究所 | グリズム |
| DE10331906B4 (de) * | 2003-07-15 | 2005-06-16 | Leica Microsystems Heidelberg Gmbh | Lichtquelle mit einem Mikrostruktuierten optischen Element und Mikroskop mit Lichtquelle |
-
2001
- 2001-11-29 US US09/999,182 patent/US6831781B2/en not_active Expired - Lifetime
-
2002
- 2002-11-27 WO PCT/US2002/038335 patent/WO2003046636A1/en not_active Ceased
- 2002-11-27 EP EP02786831.4A patent/EP1461654A4/en not_active Withdrawn
- 2002-11-27 AU AU2002351184A patent/AU2002351184A1/en not_active Abandoned
- 2002-11-27 JP JP2003548016A patent/JP2005510323A/ja active Pending
-
2009
- 2009-12-25 JP JP2009294737A patent/JP2010107519A/ja active Pending
-
2012
- 2012-10-19 JP JP2012231709A patent/JP2013056165A/ja active Pending
-
2015
- 2015-02-16 JP JP2015027425A patent/JP6098953B2/ja not_active Expired - Fee Related
Cited By (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9664615B2 (en) | 2004-07-02 | 2017-05-30 | The General Hospital Corporation | Imaging system and related techniques |
| US9763623B2 (en) | 2004-08-24 | 2017-09-19 | The General Hospital Corporation | Method and apparatus for imaging of vessel segments |
| JP2008541891A (ja) * | 2005-05-31 | 2008-11-27 | ダブリュ・オー・エム・ワールド・オブ・メディスン・アー・ゲー | 組織を視覚的に特徴づけるための方法および装置 |
| US10426548B2 (en) | 2006-02-01 | 2019-10-01 | The General Hosppital Corporation | Methods and systems for providing electromagnetic radiation to at least one portion of a sample using conformal laser therapy procedures |
| USRE46412E1 (en) | 2006-02-24 | 2017-05-23 | The General Hospital Corporation | Methods and systems for performing angle-resolved Fourier-domain optical coherence tomography |
| US9968245B2 (en) | 2006-10-19 | 2018-05-15 | The General Hospital Corporation | Apparatus and method for obtaining and providing imaging information associated with at least one portion of a sample, and effecting such portion(s) |
| US10835110B2 (en) | 2008-07-14 | 2020-11-17 | The General Hospital Corporation | Apparatus and method for facilitating at least partial overlap of dispersed ration on at least one sample |
| JP2014064935A (ja) * | 2008-07-14 | 2014-04-17 | General Hospital Corp | カラー内視鏡検査のための装置および方法 |
| JP2014139822A (ja) * | 2008-07-24 | 2014-07-31 | Regents Of The Univ Of California:The | ディスパーシブフーリエ変換イメージングの装置および方法 |
| JP2014097401A (ja) * | 2009-01-20 | 2014-05-29 | General Hospital Corp | 内視鏡生検装置、システム、及び方法 |
| US9615748B2 (en) | 2009-01-20 | 2017-04-11 | The General Hospital Corporation | Endoscopic biopsy apparatus, system and method |
| JP2012515576A (ja) * | 2009-01-20 | 2012-07-12 | ザ ジェネラル ホスピタル コーポレイション | 内視鏡生検装置、システム、及び方法 |
| US11490826B2 (en) | 2009-07-14 | 2022-11-08 | The General Hospital Corporation | Apparatus, systems and methods for measuring flow and pressure within a vessel |
| JP2016027903A (ja) * | 2009-10-06 | 2016-02-25 | ザ ジェネラル ホスピタル コーポレイション | 好酸球を含めた特定の細胞を撮像するための装置および方法 |
| JP2013507189A (ja) * | 2009-10-06 | 2013-03-04 | ザ ジェネラル ホスピタル コーポレーション | 好酸球を含めた特定の細胞を撮像するための装置および方法 |
| US10463254B2 (en) | 2010-03-05 | 2019-11-05 | The General Hospital Corporation | Light tunnel and lens which provide extended focal depth of at least one anatomical structure at a particular resolution |
| US9642531B2 (en) | 2010-03-05 | 2017-05-09 | The General Hospital Corporation | Systems, methods and computer-accessible medium which provide microscopic images of at least one anatomical structure at a particular resolution |
| US9951269B2 (en) | 2010-05-03 | 2018-04-24 | The General Hospital Corporation | Apparatus, method and system for generating optical radiation from biological gain media |
| US9795301B2 (en) | 2010-05-25 | 2017-10-24 | The General Hospital Corporation | Apparatus, systems, methods and computer-accessible medium for spectral analysis of optical coherence tomography images |
| US10939825B2 (en) | 2010-05-25 | 2021-03-09 | The General Hospital Corporation | Systems, devices, methods, apparatus and computer-accessible media for providing optical imaging of structures and compositions |
| US10285568B2 (en) | 2010-06-03 | 2019-05-14 | The General Hospital Corporation | Apparatus and method for devices for imaging structures in or at one or more luminal organs |
| US9629528B2 (en) | 2012-03-30 | 2017-04-25 | The General Hospital Corporation | Imaging system, method and distal attachment for multidirectional field of view endoscopy |
| US11490797B2 (en) | 2012-05-21 | 2022-11-08 | The General Hospital Corporation | Apparatus, device and method for capsule microscopy |
| US9968261B2 (en) | 2013-01-28 | 2018-05-15 | The General Hospital Corporation | Apparatus and method for providing diffuse spectroscopy co-registered with optical frequency domain imaging |
| US10893806B2 (en) | 2013-01-29 | 2021-01-19 | The General Hospital Corporation | Apparatus, systems and methods for providing information regarding the aortic valve |
| US11179028B2 (en) | 2013-02-01 | 2021-11-23 | The General Hospital Corporation | Objective lens arrangement for confocal endomicroscopy |
| US10478072B2 (en) | 2013-03-15 | 2019-11-19 | The General Hospital Corporation | Methods and system for characterizing an object |
| US9784681B2 (en) | 2013-05-13 | 2017-10-10 | The General Hospital Corporation | System and method for efficient detection of the phase and amplitude of a periodic modulation associated with self-interfering fluorescence |
| US10117576B2 (en) | 2013-07-19 | 2018-11-06 | The General Hospital Corporation | System, method and computer accessible medium for determining eye motion by imaging retina and providing feedback for acquisition of signals from the retina |
| US11452433B2 (en) | 2013-07-19 | 2022-09-27 | The General Hospital Corporation | Imaging apparatus and method which utilizes multidirectional field of view endoscopy |
| US10058250B2 (en) | 2013-07-26 | 2018-08-28 | The General Hospital Corporation | System, apparatus and method for utilizing optical dispersion for fourier-domain optical coherence tomography |
| US9733460B2 (en) | 2014-01-08 | 2017-08-15 | The General Hospital Corporation | Method and apparatus for microscopic imaging |
| US10736494B2 (en) | 2014-01-31 | 2020-08-11 | The General Hospital Corporation | System and method for facilitating manual and/or automatic volumetric imaging with real-time tension or force feedback using a tethered imaging device |
| US10228556B2 (en) | 2014-04-04 | 2019-03-12 | The General Hospital Corporation | Apparatus and method for controlling propagation and/or transmission of electromagnetic radiation in flexible waveguide(s) |
| US10912462B2 (en) | 2014-07-25 | 2021-02-09 | The General Hospital Corporation | Apparatus, devices and methods for in vivo imaging and diagnosis |
| US12611089B2 (en) | 2022-09-02 | 2026-04-28 | The General Hospital Corporation | Imaging apparatus and method which utilizes multidirectional field of view endoscopy |
Also Published As
| Publication number | Publication date |
|---|---|
| US20020122246A1 (en) | 2002-09-05 |
| WO2003046636A9 (en) | 2004-02-26 |
| JP2013056165A (ja) | 2013-03-28 |
| WO2003046636A1 (en) | 2003-06-05 |
| AU2002351184A1 (en) | 2003-06-10 |
| JP2010107519A (ja) | 2010-05-13 |
| EP1461654A4 (en) | 2013-10-02 |
| JP6098953B2 (ja) | 2017-03-22 |
| JP2015157073A (ja) | 2015-09-03 |
| US6831781B2 (en) | 2004-12-14 |
| EP1461654A1 (en) | 2004-09-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6098953B2 (ja) | 多重スペクトルコード化を用いる共焦点顕微鏡法並びに分光法コード化共焦点顕微鏡法のためのシステム及び装置 | |
| AU758078B2 (en) | Confocal microscopy with multi-spectral encoding | |
| JP5371433B2 (ja) | スペクトル符号化による光学イメージング方法および装置 | |
| US9295391B1 (en) | Spectrally encoded miniature endoscopic imaging probe | |
| JP5844792B2 (ja) | 内視鏡生検装置、システム、及び方法 | |
| US7242833B2 (en) | Method and apparatus for high resolution coherent optical imaging | |
| US20150116726A1 (en) | Arrangements, devices, endoscopes, catheters and methods for performing optical imaging by simultaneously illuminating and detecting multiple points on a sample | |
| Wang et al. | Optical coherence tomography for noninvasive diagnosis of epithelial cancers | |
| JP4755934B2 (ja) | 波長可変レーザ装置および光断層画像化装置 | |
| Pitris et al. | A Novel GRISM-Based Probe for Spectrally Encoded Confocal Microscopy | |
| KUMAR et al. | Biomedical Imaging: MEMS scanners enable in vivo 3-D OCT While nonoptical medical imaging techniques such as computed tomography, magnetic-resonance imaging, and ultrasound can be very useful in guiding surgical procedures, they lack the spatial resolution required for revealing tissue microarchitecture, which can be important in time-critical applications, such as staging of tumors. | |
| Bouma et al. | Optical coherence tomography for upper gastrointestinal tract diagnosis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20051128 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20051128 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20081118 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20090218 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20090225 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20090518 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20090825 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20091225 |
|
| A911 | Transfer to examiner for re-examination before appeal (zenchi) |
Free format text: JAPANESE INTERMEDIATE CODE: A911 Effective date: 20100209 |
|
| A912 | Re-examination (zenchi) completed and case transferred to appeal board |
Free format text: JAPANESE INTERMEDIATE CODE: A912 Effective date: 20100305 |