JP2005507901A - クロマン類 - Google Patents

クロマン類 Download PDF

Info

Publication number
JP2005507901A
JP2005507901A JP2003532498A JP2003532498A JP2005507901A JP 2005507901 A JP2005507901 A JP 2005507901A JP 2003532498 A JP2003532498 A JP 2003532498A JP 2003532498 A JP2003532498 A JP 2003532498A JP 2005507901 A JP2005507901 A JP 2005507901A
Authority
JP
Japan
Prior art keywords
mmol
dihydro
mixture
chromen
methoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2003532498A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005507901A5 (https=
Inventor
ディートリッヒ・シャーリング
ヴォルフガング・カール
ディートリッヒ・ザイデル
コリンナ・ヴァインツ
ルドルフ・ショーエ−ロープ
フランク・マウラー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer Healthcare AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare AG filed Critical Bayer Healthcare AG
Publication of JP2005507901A publication Critical patent/JP2005507901A/ja
Publication of JP2005507901A5 publication Critical patent/JP2005507901A5/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2003532498A 2001-10-01 2002-09-18 クロマン類 Withdrawn JP2005507901A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10148425A DE10148425A1 (de) 2001-10-01 2001-10-01 Chromane
PCT/EP2002/010447 WO2003029250A1 (de) 2001-10-01 2002-09-18 Benzisothiazolyl-substituerte aminomethylcromane zur behandlung von erkrankungen des zentralen nervensystems

Publications (2)

Publication Number Publication Date
JP2005507901A true JP2005507901A (ja) 2005-03-24
JP2005507901A5 JP2005507901A5 (https=) 2006-01-05

Family

ID=7700998

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003532498A Withdrawn JP2005507901A (ja) 2001-10-01 2002-09-18 クロマン類

Country Status (6)

Country Link
US (1) US6919360B2 (https=)
EP (1) EP1434777A1 (https=)
JP (1) JP2005507901A (https=)
CA (1) CA2462142A1 (https=)
DE (1) DE10148425A1 (https=)
WO (1) WO2003029250A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007519679A (ja) * 2004-01-30 2007-07-19 シュワルツ・ファルマ・ソシエダド・リミタダ 神経保護活性を有するジアザ−またはチアザジオン誘導体

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2199086B1 (es) 2002-07-31 2005-06-01 Cepa Schwarz Pharma Sl Nuevos derivados de cicloalcanodionas, procedimiento para su preparacion y sus aplicaciones farmacologicas.
EP1856126A2 (en) * 2005-02-17 2007-11-21 Wyeth a Corporation of the State of Delaware Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3901814A1 (de) 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
DE19522088A1 (de) * 1995-06-19 1997-01-02 Bayer Ag Benzisothiazolyl-substituierte Aminomethylchromane
DE19543476A1 (de) * 1995-11-22 1997-05-28 Troponwerke Gmbh & Co Kg Verwendung von substituierten Aminomethyl-chromanen zur Behandlung von Schädel-Hirn-Trauma

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007519679A (ja) * 2004-01-30 2007-07-19 シュワルツ・ファルマ・ソシエダド・リミタダ 神経保護活性を有するジアザ−またはチアザジオン誘導体

Also Published As

Publication number Publication date
DE10148425A1 (de) 2003-04-17
US6919360B2 (en) 2005-07-19
US20040259924A1 (en) 2004-12-23
WO2003029250A1 (de) 2003-04-10
CA2462142A1 (en) 2003-04-10
EP1434777A1 (de) 2004-07-07

Similar Documents

Publication Publication Date Title
CN1104430C (zh) 抑制血管生成的哒嗪胺
JP6126528B2 (ja) 神経新生促進化合物
TW201326182A (zh) 六氫哌喃並［３，４－ｄ］［１，３］噻□－２－胺化合物類
CA2882826A1 (en) Pro-neurogenic compounds
JPH05279357A (ja) アザヘテロサイクリルメチル−クロマン類
EP3126361B1 (en) Chromene and 1,1a,2,7b-tetrahydrocyclopropa[c]chromene pyridopyrazinediones as gamma-secretase modulators
WO2010129467A1 (en) Compounds and methods for inhibition of renin, and indications therefor
JP2003521468A (ja) エストロゲンレセプタを変調させるための化合物及び方法
TW201300384A (zh) 新穎的雙環吡啶酮類
JP2004525861A (ja) エストロゲン受容体を調節する化合物および方法
KR20170063599A (ko) NR2B의 N-알킬아릴-5-옥시아릴-옥타히드로-시클로펜타[c]피롤 음성 알로스테릭 조정제
EP2280955A2 (en) Crystalline form of 6-ý(4s)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl¨pyridazin-3-amine
JPH0717633B2 (ja) ヘテロアリールピペラジン抗精神病薬
JPH07500353A (ja) ５−ｈｔ１アゴニストとしてのインドール誘導体
US9765073B2 (en) Cyclopropabenzofuranyl pyridopyrazinediones
JP2001512727A (ja) ５ｈｔ−１受容体のリガンドとしてのニ環式化合物
JPH06211655A (ja) 乗物酔いおよび嘔吐症の処置用６−ヘテロ環−４−アミノ−１，３，４，５−テトラヒドロベンズ［ｃｄ］インドール類
JP2005507901A (ja) クロマン類
JP6943239B2 (ja) Ｋｃｎｑ２〜５チャネル活性化剤
JP2007530648A (ja) Ｃｎｓ障害の処置のための、５−ｈｔ６受容体アンタゴニストとしての３−（（ヘテロ）アリールスルフォニル）−８−（（アミノアルキル）オキシ）キノリン
EP0929550A1 (fr) DERIVES DE $i(N)-(BENZOTHIAZOL-2-YL)PIPERIDINE-1-ETHANAMINE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
JP2002512630A (ja) 血管形成抑制チアジアゾリルピリダジン誘導体
JP5165578B2 (ja) イソキノリンおよびベンゾ［ｈ］イソキノリン誘導体、調製およびヒスタミンｈ３受容体のアンタゴニストとしてのこの治療上の使用
JP2002534421A (ja) １−フェニル−４−（１−［２−アリール］シクロプロピル）メチルピペラジン：ドーパミン受容体リガンド
JP6808088B2 (ja) 純粋な５−ｈｔ６受容体アンタゴニストとしてのフルオロピペリジン化合物

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20050913

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20050913

A761 Written withdrawal of application

Free format text: JAPANESE INTERMEDIATE CODE: A761

Effective date: 20060920