JP2005501108A - 神経変性治療におけるネフィラセタムの使用 - Google Patents
神経変性治療におけるネフィラセタムの使用 Download PDFInfo
- Publication number
- JP2005501108A JP2005501108A JP2003522525A JP2003522525A JP2005501108A JP 2005501108 A JP2005501108 A JP 2005501108A JP 2003522525 A JP2003522525 A JP 2003522525A JP 2003522525 A JP2003522525 A JP 2003522525A JP 2005501108 A JP2005501108 A JP 2005501108A
- Authority
- JP
- Japan
- Prior art keywords
- stroke
- nefiracetam
- patient
- treatment
- neurodegeneration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- NGHTXZCKLWZPGK-UHFFFAOYSA-N nefiracetam Chemical compound CC1=CC=CC(C)=C1NC(=O)CN1C(=O)CCC1 NGHTXZCKLWZPGK-UHFFFAOYSA-N 0.000 title claims abstract description 85
- 229950004663 nefiracetam Drugs 0.000 title claims abstract description 80
- 238000011282 treatment Methods 0.000 title claims abstract description 23
- 230000004770 neurodegeneration Effects 0.000 title claims abstract description 19
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- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 1
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- 229960001227 oxiracetam Drugs 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/JP2001/007180 WO2003018005A1 (en) | 2001-08-22 | 2001-08-22 | use of nefiracetam for treating neurodegeneration |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005501108A true JP2005501108A (ja) | 2005-01-13 |
| JP2005501108A5 JP2005501108A5 (https=) | 2008-10-16 |
Family
ID=11737657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003522525A Pending JP2005501108A (ja) | 2001-08-22 | 2001-08-22 | 神経変性治療におけるネフィラセタムの使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20040192759A1 (https=) |
| EP (1) | EP1420782B1 (https=) |
| JP (1) | JP2005501108A (https=) |
| AT (1) | ATE404192T1 (https=) |
| CA (1) | CA2457982C (https=) |
| DE (1) | DE60135390D1 (https=) |
| ES (1) | ES2311537T3 (https=) |
| WO (1) | WO2003018005A1 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008538583A (ja) * | 2005-04-20 | 2008-10-30 | ハミルトン ファーマシューティカルズ インコーポレイティド | アパシー症候群を治療するための方法 |
| JP2009531423A (ja) * | 2006-03-28 | 2009-09-03 | ヴァレンティナ イワノフナ アカプキナ | 神経親和性、神経調節性、脳血管作用性および抗発作活性を呈する薬剤 |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2865504T3 (es) * | 2008-10-16 | 2021-10-15 | Univ Johns Hopkins | Procedimientos y composiciones para la mejora de la función cognitiva |
| WO2011048208A1 (en) | 2009-10-22 | 2011-04-28 | University College Dublin, National University Of Ireland, Dublin | Causal therapy of diseases or conditions associated with cns or pns demyelination |
| AU2011215870B2 (en) * | 2010-02-09 | 2016-01-28 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| US20140206667A1 (en) | 2012-11-14 | 2014-07-24 | Michela Gallagher | Methods and compositions for treating schizophrenia |
| JP6433482B2 (ja) | 2013-03-15 | 2018-12-05 | エージンバイオ， インコーポレイテッド | 認知機能を改善するための方法および組成物 |
| WO2014144663A1 (en) | 2013-03-15 | 2014-09-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| WO2016191288A1 (en) | 2015-05-22 | 2016-12-01 | Agenebio, Inc. | Extended release pharmaceutical compositions of levetiracetam |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05163145A (ja) * | 1991-05-02 | 1993-06-29 | Dai Ichi Seiyaku Co Ltd | 脳血管性痴呆改善剤 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4749700A (en) * | 1984-10-23 | 1988-06-07 | Nastech Pharmaceutical Co, Inc. | Novel methods of administering antihistamines, antinausea and antiemetic pharmaceutical agents and novel dosage forms containing same |
| SK279285B6 (sk) * | 1991-05-02 | 1998-09-09 | Daiichi Pharmaceutical Co. | Použitie n-(2,6-dimetylfenyl)-2-(2-oxo-1-pyrolidin |
| DE69823851D1 (de) * | 1997-07-15 | 2004-06-17 | Daiichi Seiyaku Co | Nefiracetam zur prophylaxe und behandlung von propofol verursachtem gedächtnisschwund |
| JPH1180027A (ja) * | 1997-09-12 | 1999-03-23 | Dai Ichi Seiyaku Co Ltd | 向知性薬 |
| US6423739B1 (en) * | 2000-02-23 | 2002-07-23 | Daiichi Pharmaceutical Co., Ltd. | Method for aiding cerebral recovery following neurodegeneration |
-
2001
- 2001-08-22 JP JP2003522525A patent/JP2005501108A/ja active Pending
- 2001-08-22 DE DE60135390T patent/DE60135390D1/de not_active Expired - Lifetime
- 2001-08-22 AT AT01958395T patent/ATE404192T1/de not_active IP Right Cessation
- 2001-08-22 CA CA002457982A patent/CA2457982C/en not_active Expired - Fee Related
- 2001-08-22 WO PCT/JP2001/007180 patent/WO2003018005A1/en not_active Ceased
- 2001-08-22 US US10/487,320 patent/US20040192759A1/en not_active Abandoned
- 2001-08-22 ES ES01958395T patent/ES2311537T3/es not_active Expired - Lifetime
- 2001-08-22 EP EP01958395A patent/EP1420782B1/en not_active Expired - Lifetime
-
2007
- 2007-09-28 US US11/863,808 patent/US20080076820A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05163145A (ja) * | 1991-05-02 | 1993-06-29 | Dai Ichi Seiyaku Co Ltd | 脳血管性痴呆改善剤 |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008538583A (ja) * | 2005-04-20 | 2008-10-30 | ハミルトン ファーマシューティカルズ インコーポレイティド | アパシー症候群を治療するための方法 |
| JP2009531423A (ja) * | 2006-03-28 | 2009-09-03 | ヴァレンティナ イワノフナ アカプキナ | 神経親和性、神経調節性、脳血管作用性および抗発作活性を呈する薬剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003018005A1 (en) | 2003-03-06 |
| US20080076820A1 (en) | 2008-03-27 |
| ES2311537T3 (es) | 2009-02-16 |
| CA2457982C (en) | 2009-11-03 |
| DE60135390D1 (de) | 2008-09-25 |
| EP1420782A1 (en) | 2004-05-26 |
| EP1420782B1 (en) | 2008-08-13 |
| ATE404192T1 (de) | 2008-08-15 |
| US20040192759A1 (en) | 2004-09-30 |
| CA2457982A1 (en) | 2003-03-06 |
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