JP2005292112A - 生物学的材料の存在を検出し画像化するための方法及び装置 - Google Patents

生物学的材料の存在を検出し画像化するための方法及び装置 Download PDF

Info

Publication number
JP2005292112A
JP2005292112A JP2004151028A JP2004151028A JP2005292112A JP 2005292112 A JP2005292112 A JP 2005292112A JP 2004151028 A JP2004151028 A JP 2004151028A JP 2004151028 A JP2004151028 A JP 2004151028A JP 2005292112 A JP2005292112 A JP 2005292112A
Authority
JP
Japan
Prior art keywords
fluorescence
biological
excitation
biological material
region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2004151028A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005292112A5 (enExample
Inventor
Linda S Powers
エス. パワーズ リンダ
Christopher R Lloyd
アール. ロイド クリストファー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MicroBioSystems LP
Original Assignee
MicroBioSystems LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MicroBioSystems LP filed Critical MicroBioSystems LP
Publication of JP2005292112A publication Critical patent/JP2005292112A/ja
Publication of JP2005292112A5 publication Critical patent/JP2005292112A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6486Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/274Calibration, base line adjustment, drift correction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55Specular reflectivity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6456Spatial resolved fluorescence measurements; Imaging
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N2021/1734Sequential different kinds of measurements; Combining two or more methods
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N2021/6417Spectrofluorimetric devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/33Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using ultraviolet light

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mathematical Physics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2004151028A 2004-04-02 2004-05-20 生物学的材料の存在を検出し画像化するための方法及び装置 Pending JP2005292112A (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/817,647 US7186990B2 (en) 2002-01-22 2004-04-02 Method and apparatus for detecting and imaging the presence of biological materials

Publications (2)

Publication Number Publication Date
JP2005292112A true JP2005292112A (ja) 2005-10-20
JP2005292112A5 JP2005292112A5 (enExample) 2007-06-07

Family

ID=34887789

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004151028A Pending JP2005292112A (ja) 2004-04-02 2004-05-20 生物学的材料の存在を検出し画像化するための方法及び装置

Country Status (6)

Country Link
US (1) US7186990B2 (enExample)
EP (1) EP1582860A1 (enExample)
JP (1) JP2005292112A (enExample)
CN (1) CN100561200C (enExample)
CA (1) CA2466433A1 (enExample)
SG (1) SG144722A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007163873A (ja) * 2005-12-14 2007-06-28 Optrex Corp 汚染物質の除去方法
WO2019012765A1 (ja) * 2017-07-11 2019-01-17 浜松ホトニクス株式会社 試料観察装置及び試料観察方法

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6380751B2 (en) 1992-06-11 2002-04-30 Cascade Microtech, Inc. Wafer probe station having environment control enclosure
US5345170A (en) 1992-06-11 1994-09-06 Cascade Microtech, Inc. Wafer probe station having integrated guarding, Kelvin connection and shielding systems
US5561377A (en) 1995-04-14 1996-10-01 Cascade Microtech, Inc. System for evaluating probing networks
US6232789B1 (en) 1997-05-28 2001-05-15 Cascade Microtech, Inc. Probe holder for low current measurements
US5914613A (en) 1996-08-08 1999-06-22 Cascade Microtech, Inc. Membrane probing system with local contact scrub
US6002263A (en) 1997-06-06 1999-12-14 Cascade Microtech, Inc. Probe station having inner and outer shielding
US6256882B1 (en) 1998-07-14 2001-07-10 Cascade Microtech, Inc. Membrane probing system
US6578264B1 (en) 1999-06-04 2003-06-17 Cascade Microtech, Inc. Method for constructing a membrane probe using a depression
US6445202B1 (en) 1999-06-30 2002-09-03 Cascade Microtech, Inc. Probe station thermal chuck with shielding for capacitive current
US6838890B2 (en) 2000-02-25 2005-01-04 Cascade Microtech, Inc. Membrane probing system
US6914423B2 (en) 2000-09-05 2005-07-05 Cascade Microtech, Inc. Probe station
US6965226B2 (en) 2000-09-05 2005-11-15 Cascade Microtech, Inc. Chuck for holding a device under test
DE20114544U1 (de) 2000-12-04 2002-02-21 Cascade Microtech, Inc., Beaverton, Oreg. Wafersonde
AU2002327490A1 (en) 2001-08-21 2003-06-30 Cascade Microtech, Inc. Membrane probing system
US6777964B2 (en) 2002-01-25 2004-08-17 Cascade Microtech, Inc. Probe station
KR100864916B1 (ko) 2002-05-23 2008-10-22 캐스케이드 마이크로테크 인코포레이티드 피시험 디바이스를 테스트하기 위한 프로브
US6847219B1 (en) 2002-11-08 2005-01-25 Cascade Microtech, Inc. Probe station with low noise characteristics
US6724205B1 (en) 2002-11-13 2004-04-20 Cascade Microtech, Inc. Probe for combined signals
US7250779B2 (en) 2002-11-25 2007-07-31 Cascade Microtech, Inc. Probe station with low inductance path
US6861856B2 (en) 2002-12-13 2005-03-01 Cascade Microtech, Inc. Guarded tub enclosure
US7221172B2 (en) 2003-05-06 2007-05-22 Cascade Microtech, Inc. Switched suspended conductor and connection
US7057404B2 (en) 2003-05-23 2006-06-06 Sharp Laboratories Of America, Inc. Shielded probe for testing a device under test
US7492172B2 (en) 2003-05-23 2009-02-17 Cascade Microtech, Inc. Chuck for holding a device under test
US7250626B2 (en) 2003-10-22 2007-07-31 Cascade Microtech, Inc. Probe testing structure
US7187188B2 (en) 2003-12-24 2007-03-06 Cascade Microtech, Inc. Chuck with integrated wafer support
DE202004021093U1 (de) 2003-12-24 2006-09-28 Cascade Microtech, Inc., Beaverton Aktiver Halbleiterscheibenmessfühler
EP1754072A2 (en) 2004-06-07 2007-02-21 CASCADE MICROTECH, INC. (an Oregon corporation) Thermal optical chuck
US7330041B2 (en) 2004-06-14 2008-02-12 Cascade Microtech, Inc. Localizing a temperature of a device for testing
EP1766426B1 (en) 2004-07-07 2013-09-11 Cascade Microtech, Inc. Probe head having a membrane suspended probe
WO2006022823A1 (en) 2004-07-29 2006-03-02 Centrus International, Inc. Detection of microorganisms with a fluorescence-based device
EP1789812A2 (en) 2004-09-13 2007-05-30 Cascade Microtech, Inc. Double sided probing structures
US7545969B2 (en) * 2004-12-16 2009-06-09 Alliant Techsystems Inc. Method and system for wide-area ultraviolet detection of forensic evidence
US7535247B2 (en) 2005-01-31 2009-05-19 Cascade Microtech, Inc. Interface for testing semiconductors
US7656172B2 (en) 2005-01-31 2010-02-02 Cascade Microtech, Inc. System for testing semiconductors
JP2006263044A (ja) * 2005-03-23 2006-10-05 Fuji Photo Film Co Ltd 蛍光検出システム
US7449899B2 (en) 2005-06-08 2008-11-11 Cascade Microtech, Inc. Probe for high frequency signals
JP5080459B2 (ja) 2005-06-13 2012-11-21 カスケード マイクロテック インコーポレイテッド 広帯域能動/受動差動信号プローブ
DE112007001399T5 (de) 2006-06-09 2009-05-07 Cascade Microtech, Inc., Beaverton Messfühler für differentielle Signale mit integrierter Symmetrieschaltung
US7443186B2 (en) 2006-06-12 2008-10-28 Cascade Microtech, Inc. On-wafer test structures for differential signals
US7764072B2 (en) 2006-06-12 2010-07-27 Cascade Microtech, Inc. Differential signal probing system
US7723999B2 (en) 2006-06-12 2010-05-25 Cascade Microtech, Inc. Calibration structures for differential signal probing
US7403028B2 (en) 2006-06-12 2008-07-22 Cascade Microtech, Inc. Test structure and probe for differential signals
DE102006000318A1 (de) 2006-07-03 2008-01-10 Novineon Healthcare Technology Partners Gmbh Vorrichtung zur Blutungsdetektion
US20080012578A1 (en) * 2006-07-14 2008-01-17 Cascade Microtech, Inc. System for detecting molecular structure and events
US7876114B2 (en) 2007-08-08 2011-01-25 Cascade Microtech, Inc. Differential waveguide probe
US7615761B2 (en) 2007-09-10 2009-11-10 Coherent, Inc. Trace evidence detection using multiple laser light sources
WO2009036105A2 (en) * 2007-09-11 2009-03-19 Baxter International Inc Infusion therapy sensor system
US8512975B2 (en) * 2008-07-24 2013-08-20 Biomerieux, Inc. Method for detection and characterization of a microorganism in a sample using time dependent spectroscopic measurements
US7888957B2 (en) 2008-10-06 2011-02-15 Cascade Microtech, Inc. Probing apparatus with impedance optimized interface
US8652800B2 (en) * 2008-10-31 2014-02-18 Biomerieux, Inc. Method for separation, characterization and/or identification of microorganisms using spectroscopy
CA2741036C (en) * 2008-10-31 2018-01-09 Biomerieux, Inc. Methods for separation, characterization, and/or identification of microorganisms using raman spectroscopy
WO2010062350A1 (en) * 2008-10-31 2010-06-03 Biomerieux, Inc. Methods for detection, characterization and/or identification of microorganisms in a sealed container
JP5509213B2 (ja) 2008-10-31 2014-06-04 ビオメリュー・インコーポレイテッド 質量分析を使用した微生物の分離、キャラクタリゼーションおよび/または同定方法
US8647835B2 (en) 2008-10-31 2014-02-11 BIO MéRIEUX, INC. Methods for separation, characterization and/or identification of microorganisms using spectroscopy
JP2012507710A (ja) * 2008-10-31 2012-03-29 バイオメリュー・インコーポレイテッド 同定作用物質を使用した微生物の分離、キャラクタリゼーションおよび/または同定方法
EP2364447B1 (en) * 2008-10-31 2019-06-12 Biomerieux, Inc Method for the identification of microorganisms
US8410806B2 (en) 2008-11-21 2013-04-02 Cascade Microtech, Inc. Replaceable coupon for a probing apparatus
US8319503B2 (en) 2008-11-24 2012-11-27 Cascade Microtech, Inc. Test apparatus for measuring a characteristic of a device under test
EP2376914B1 (en) * 2008-12-16 2017-04-19 Biomerieux, Inc Methods for the characterization of microorganisms on solid or semi-solid media
CA2760982C (en) * 2009-05-15 2019-01-15 Biomerieux, Inc. System and methods for rapid identification and/or characterization of a microbial agent in a sample
US9150900B2 (en) 2009-05-15 2015-10-06 Biomerieux, Inc. Automated transfer mechanism for microbial detection apparatus
BR112012031252B1 (pt) * 2010-06-11 2020-06-30 B. Braun Avitum Ag aparelho para tratamento extracorpóreo de sangue
WO2012035705A1 (ja) * 2010-09-17 2012-03-22 国立大学法人東北大学 抗体を成分として含む医薬品の有効性の判定方法
RU2013124008A (ru) * 2010-10-27 2014-12-10 Конинклейке Филипс Электроникс Н.В. Система обнаружения присутствия и система освещения
US20120119110A1 (en) * 2010-11-16 2012-05-17 Research In Motion Limited Apparatus, and associated method, for detecting contamination of an object
EP2520923A1 (en) * 2011-05-06 2012-11-07 bioMérieux Bio-imaging method and system
EP2795306B1 (en) 2011-12-22 2022-06-15 Becton, Dickinson and Company Methods and apparatus for rapid detection of infectious microorganisms
US9605294B2 (en) 2012-09-04 2017-03-28 Becton, Dickinson And Company Bacterial pre-concentration and detection technique
US20140125809A1 (en) 2012-11-02 2014-05-08 Syntronics, Llc Digital ruvis camera
WO2015089514A2 (en) * 2013-12-13 2015-06-18 Colorado State University Research Foundation Nano-stamp and matched reader for anti-counterfeiting applications
US10039934B2 (en) * 2013-12-30 2018-08-07 PhotonEdge Inc. Multi-wavelength interleaved optical stimulation
US10772553B2 (en) 2014-08-07 2020-09-15 Teleflex Medical Incorporated Urine sensing optical fiber probe and system for percutaneous nephrostomy
US9880159B2 (en) 2014-10-01 2018-01-30 Linda S. Powers Cartridge-based detection system
US9867250B1 (en) 2015-04-20 2018-01-09 The Arizona Board Of Regents On Behalf Of The University Of Arizona System having a configurable pico-second pulsed LED driver circuit and photomultiplier tube biasing and gating circuits for real-time, time-resolved transient recording of fluorescence
CN109863503B (zh) * 2016-09-02 2023-05-23 英维特公司 用于单分子定量的系统和方法
EP3559721B1 (en) * 2016-12-23 2021-09-15 Bio-Rad Laboratories, Inc. Reduction of background signal in blot images
JP7014794B2 (ja) * 2017-07-11 2022-02-01 浜松ホトニクス株式会社 試料観察装置及び試料観察方法
CN110197174A (zh) * 2018-02-26 2019-09-03 刘风华 文物、字画和原产商品的数字化技术
US11269203B2 (en) 2020-01-23 2022-03-08 Hong Kong Applied Science And Technology Institute Company Limited Multifocal system with polarization-independent focusing
US11408825B2 (en) 2020-08-28 2022-08-09 Hong Kong Applied Science and Technology Research Institute Company Limited Forensic detector and the system thereof

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3580525A (en) * 1967-11-21 1971-05-25 Telefunken Patent Arrangement maintaining constant tape tension in magnetic tape recorders
US3850525A (en) 1973-07-09 1974-11-26 Beckman Instruments Inc Simultaneous multiple measurements in laser photometers
US4745285A (en) * 1986-08-21 1988-05-17 Becton Dickinson And Company Multi-color fluorescence analysis with single wavelength excitation
US4900934A (en) * 1987-07-15 1990-02-13 University Of Utah Apparatus for simultaneous visualization and measurement of fluorescence from fluorescent dye-treated cell preparations and solutions
US5208651A (en) * 1991-07-16 1993-05-04 The Regents Of The University Of California Apparatus and method for measuring fluorescence intensities at a plurality of wavelengths and lifetimes
US5294799A (en) * 1993-02-01 1994-03-15 Aslund Nils R D Apparatus for quantitative imaging of multiple fluorophores
US5418371A (en) * 1993-02-01 1995-05-23 Aslund; Nils R. D. Apparatus for quantitative imaging of multiple fluorophores using dual detectors
US5424959A (en) * 1993-07-19 1995-06-13 Texaco Inc. Interpretation of fluorescence fingerprints of crude oils and other hydrocarbon mixtures using neural networks
US5474910A (en) * 1993-10-15 1995-12-12 Alfano; Robert R. Method and device for detecting biological molecules and/or microorganisms within a desired area or space
US5491343A (en) * 1994-03-25 1996-02-13 Brooker; Gary High-speed multiple wavelength illumination source, apparatus containing the same, and applications thereof to methods of irradiating luminescent samples and of quantitative luminescence ratio microscopy
US5701012A (en) * 1996-03-19 1997-12-23 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of National Defence Fluorescent biological particle detection system
US5760406A (en) * 1996-06-03 1998-06-02 Powers; Linda Method and apparatus for sensing the presence of microbes
US5866430A (en) * 1996-06-13 1999-02-02 Grow; Ann E. Raman optrode processes and devices for detection of chemicals and microorganisms
WO1998059233A1 (en) * 1997-06-23 1998-12-30 Luminex Corporation Interlaced lasers for multiple fluorescence measurement
US6124597A (en) * 1997-07-07 2000-09-26 Cedars-Sinai Medical Center Method and devices for laser induced fluorescence attenuation spectroscopy
US5968766A (en) * 1998-03-31 1999-10-19 B.E. Safe Method and apparatus for sensing the presence of microbes
US6750006B2 (en) * 2002-01-22 2004-06-15 Microbiosystems, Limited Partnership Method for detecting the presence of microbes and determining their physiological status

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007163873A (ja) * 2005-12-14 2007-06-28 Optrex Corp 汚染物質の除去方法
WO2019012765A1 (ja) * 2017-07-11 2019-01-17 浜松ホトニクス株式会社 試料観察装置及び試料観察方法
JP7007122B2 (ja) 2017-07-11 2022-01-24 浜松ホトニクス株式会社 試料観察装置及び試料観察方法
US11340165B2 (en) 2017-07-11 2022-05-24 Hamamatsu Photonics K.K. Sample observation device and sample observation method

Also Published As

Publication number Publication date
CN1677088A (zh) 2005-10-05
SG144722A1 (en) 2008-08-28
US20040197771A1 (en) 2004-10-07
EP1582860A1 (en) 2005-10-05
CA2466433A1 (en) 2005-10-02
US7186990B2 (en) 2007-03-06
CN100561200C (zh) 2009-11-18

Similar Documents

Publication Publication Date Title
JP2005292112A (ja) 生物学的材料の存在を検出し画像化するための方法及び装置
JP4033754B2 (ja) 微生物の存在の検出及びその生理学的状態の決定のための方法及び装置
Estes et al. Reagentless detection of microorganisms by intrinsic fluorescence
EP3513172B1 (en) System and method for time-resolved fluoroimmunoassay detection
US8423104B2 (en) Haemozoin detection
EP1672354A1 (en) Method and system for wide area ultra violet detection forensic evidence
US6979828B2 (en) Method and apparatus for immediately determining microorganism
US20240241080A1 (en) Using electrophoresis for disease detection based on controlled molecular charge
JP4487985B2 (ja) 微生物計量装置
KR20180024900A (ko) 화합물 반도체 기반 생물입자 검출 장치 및 방법
US11408825B2 (en) Forensic detector and the system thereof
CN212199262U (zh) 一种基于激光光谱技术的病菌检测仪器
Lloyd Powers et al.
CN103472040B (zh) 荧光检测方法
JP2006262775A (ja) 微生物細胞検出方法
JP2006017688A (ja) 自家蛍光による角層細胞の鑑別方法
JP2006333812A (ja) 微生物計量方法および微生物計量装置
JP2005287494A (ja) 休眠状態のクリプトバイオティックな微生物の存在を検出する方法
HK1056912B (en) Method and apparatus for detecting the presence of microbes and determining their physiological status
WO2022087657A1 (en) A non-invasive, intelligent tool for continous virus monitoring and rapid detection of known and unkown viruses
WO2024037674A1 (es) Dispositivo de detección de la enfermedad hlb
Nonitha et al. Dried Salivary Stain Detection using Ultraviolet-Light Spectrophotometer, Fluorescent and Raman Spectroscopy
ATE451608T1 (de) Vorrichtung zur erfassung der konzentration einer fluoreszierenden substanz in einem fluid, insbesondere in einem kraftstoff

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20070416

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070416

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20090609

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20090630

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20090924

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20090929

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20091029

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20091104

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20091130

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20091203

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20100309