JP2004534763A5 - - Google Patents
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- Publication number
- JP2004534763A5 JP2004534763A5 JP2002590936A JP2002590936A JP2004534763A5 JP 2004534763 A5 JP2004534763 A5 JP 2004534763A5 JP 2002590936 A JP2002590936 A JP 2002590936A JP 2002590936 A JP2002590936 A JP 2002590936A JP 2004534763 A5 JP2004534763 A5 JP 2004534763A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- less
- composition according
- tobramycin
- spray
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 19
- 239000002647 aminoglycoside antibiotic agent Substances 0.000 claims 12
- 239000007921 spray Substances 0.000 claims 10
- 229960000707 tobramycin Drugs 0.000 claims 10
- NLVFBUXFDBBNBW-PBSUHMDJSA-N tobramycin Chemical compound N[C@@H]1C[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N NLVFBUXFDBBNBW-PBSUHMDJSA-N 0.000 claims 10
- 229940126574 aminoglycoside antibiotic Drugs 0.000 claims 9
- 238000009472 formulation Methods 0.000 claims 9
- 239000000203 mixture Substances 0.000 claims 9
- 239000000443 aerosol Substances 0.000 claims 8
- 239000007864 aqueous solution Substances 0.000 claims 6
- 239000002245 particle Substances 0.000 claims 4
- UCSJYZPVAKXKNQ-HZYVHMACSA-N streptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O UCSJYZPVAKXKNQ-HZYVHMACSA-N 0.000 claims 4
- 201000003883 Cystic fibrosis Diseases 0.000 claims 3
- 229930182566 Gentamicin Natural products 0.000 claims 2
- CEAZRRDELHUEMR-URQXQFDESA-N Gentamicin Chemical compound O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N CEAZRRDELHUEMR-URQXQFDESA-N 0.000 claims 2
- 229930193140 Neomycin Natural products 0.000 claims 2
- 229960004821 amikacin Drugs 0.000 claims 2
- LKCWBDHBTVXHDL-RMDFUYIESA-N amikacin Chemical compound O([C@@H]1[C@@H](N)C[C@H]([C@@H]([C@H]1O)O[C@@H]1[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O1)O)NC(=O)[C@@H](O)CCN)[C@H]1O[C@H](CN)[C@@H](O)[C@H](O)[C@H]1O LKCWBDHBTVXHDL-RMDFUYIESA-N 0.000 claims 2
- 229960002518 gentamicin Drugs 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 229960000318 kanamycin Drugs 0.000 claims 2
- 229930027917 kanamycin Natural products 0.000 claims 2
- SBUJHOSQTJFQJX-NOAMYHISSA-N kanamycin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N SBUJHOSQTJFQJX-NOAMYHISSA-N 0.000 claims 2
- 229930182823 kanamycin A Natural products 0.000 claims 2
- 239000006199 nebulizer Substances 0.000 claims 2
- 229960004927 neomycin Drugs 0.000 claims 2
- ZBGPYVZLYBDXKO-HILBYHGXSA-N netilmycin Chemical compound O([C@@H]1[C@@H](N)C[C@H]([C@@H]([C@H]1O)O[C@@H]1[C@]([C@H](NC)[C@@H](O)CO1)(C)O)NCC)[C@H]1OC(CN)=CC[C@H]1N ZBGPYVZLYBDXKO-HILBYHGXSA-N 0.000 claims 2
- 229960005322 streptomycin Drugs 0.000 claims 2
- 208000032536 Pseudomonas Infections Diseases 0.000 claims 1
- 229960000808 netilmicin Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29223401P | 2001-05-18 | 2001-05-18 | |
| PCT/US2002/015999 WO2002094217A1 (en) | 2001-05-18 | 2002-05-17 | Methods and unit dose formulations for the inhalation administration of aminoglycoside antibiotics |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009185305A Division JP2009269923A (ja) | 2001-05-18 | 2009-08-07 | アミノグリコシド抗生物質の吸入投与のための方法および単位用量処方物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004534763A JP2004534763A (ja) | 2004-11-18 |
| JP2004534763A5 true JP2004534763A5 (enExample) | 2006-01-05 |
Family
ID=23123791
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002590936A Pending JP2004534763A (ja) | 2001-05-18 | 2002-05-17 | アミノグリコシド抗生物質の吸入投与のための方法および単位用量処方物 |
| JP2009185305A Pending JP2009269923A (ja) | 2001-05-18 | 2009-08-07 | アミノグリコシド抗生物質の吸入投与のための方法および単位用量処方物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009185305A Pending JP2009269923A (ja) | 2001-05-18 | 2009-08-07 | アミノグリコシド抗生物質の吸入投与のための方法および単位用量処方物 |
Country Status (11)
| Country | Link |
|---|---|
| US (8) | US20030143162A1 (enExample) |
| EP (2) | EP2186508A3 (enExample) |
| JP (2) | JP2004534763A (enExample) |
| AT (1) | ATE322249T1 (enExample) |
| AU (1) | AU2010210026A1 (enExample) |
| CA (1) | CA2447600C (enExample) |
| DE (1) | DE60210402T2 (enExample) |
| DK (1) | DK1320355T3 (enExample) |
| ES (1) | ES2261735T3 (enExample) |
| PT (1) | PT1320355E (enExample) |
| WO (1) | WO2002094217A1 (enExample) |
Families Citing this family (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW465235B (en) | 1998-09-17 | 2001-11-21 | United Video Properties Inc | Electronic program guide with digital storage |
| PT1320355E (pt) * | 2001-05-18 | 2006-08-31 | Chiron Corp | Sistema para administracao de uma formulacao de tobramicina |
| US20040022740A1 (en) * | 2001-07-10 | 2004-02-05 | Baker William R. | Macrolide formulations for inhalation and methods of treatment of endobronchial infections |
| US20030059375A1 (en) * | 2001-08-20 | 2003-03-27 | Transave, Inc. | Method for treating lung cancers |
| WO2003053411A1 (en) | 2001-12-19 | 2003-07-03 | Nektar Therapeutics | Pulmonary delivery of aminoglycosides |
| US7334580B2 (en) * | 2002-05-07 | 2008-02-26 | Smaldone Gerald C | Methods, devices and formulations for targeted endobronchial therapy |
| US7607436B2 (en) * | 2002-05-06 | 2009-10-27 | The Research Foundation Of State University Of New York | Methods, devices and formulations for targeted endobronchial therapy |
| EP1545459A4 (en) * | 2002-08-02 | 2007-08-22 | Transave Inc | PLATINUM AGGREGATES, AND METHOD FOR MANUFACTURING THE SAME |
| US9186322B2 (en) * | 2002-08-02 | 2015-11-17 | Insmed Incorporated | Platinum aggregates and process for producing the same |
| AU2002953095A0 (en) * | 2002-11-29 | 2002-12-19 | Biota Scientific Management Pty Ltd | Novel chemical compounds and their use |
| CA2529817C (en) | 2003-03-10 | 2013-02-12 | Optimer Pharmaceuticals, Inc. | Novel antibacterial agents |
| ATE350024T1 (de) * | 2003-10-15 | 2007-01-15 | Pari Gmbh | Flüssige zubereitung enthaltend tobramycin |
| WO2005089448A2 (en) * | 2004-03-18 | 2005-09-29 | Transave, Inc. | Administration of cisplatin by inhalation |
| US20070065522A1 (en) * | 2004-03-18 | 2007-03-22 | Transave, Inc. | Administration of high potency platinum compound formulations by inhalation |
| ATE493969T1 (de) * | 2004-05-17 | 2011-01-15 | Corus Pharma Inc | Kombination aus fosfomycin/aminoglycosid in aerosolform zur behandlung bakterieller atemwegsinfektionen |
| AU2005245018A1 (en) * | 2004-05-21 | 2005-12-01 | Transave, Inc. | Treatment of lung diseases and pre-lung disease conditions |
| PL1765288T3 (pl) | 2004-06-18 | 2013-04-30 | Novartis Ag | Preparaty tobramycyny do leczenia zakażań oskrzeli |
| WO2006055352A2 (en) * | 2004-11-08 | 2006-05-26 | Transave, Inc. | Methods of treating cancer with lipid-based platinum compound formulations administered intraperitoneally |
| US9205050B2 (en) * | 2005-09-29 | 2015-12-08 | Bayer Intellectual Property Gmbh | Antibiotic formulations, unit doses, kits and methods |
| AU2013206401B2 (en) * | 2005-09-29 | 2016-06-23 | Novartis Ag | Antibiotic formulations, unit doses, kits, and methods |
| US9107824B2 (en) | 2005-11-08 | 2015-08-18 | Insmed Incorporated | Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally |
| US20070190182A1 (en) * | 2005-11-08 | 2007-08-16 | Pilkiewicz Frank G | Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally |
| US20070190180A1 (en) * | 2005-11-08 | 2007-08-16 | Pilkiewicz Frank G | Methods of treating cancer with high potency lipid-based platinum compound formulations administered intravenously |
| WO2007056236A2 (en) * | 2005-11-08 | 2007-05-18 | Transave, Inc. | Methods of treating cancer with lipid-based platinum compound formulations administered intravenously |
| WO2007064658A2 (en) * | 2005-11-30 | 2007-06-07 | Transave, Inc. | Safe and effective methods of administering therapeutic agents |
| AU2006322076C1 (en) | 2005-12-08 | 2013-11-14 | Insmed Incorporated | Lipid-based compositions of antiinfectives for treating pulmonary infections |
| WO2007070875A1 (en) * | 2005-12-15 | 2007-06-21 | Aerosol Science Laboratories, Inc. | Treatment of active infections and related compositions |
| JP2008199905A (ja) * | 2007-02-16 | 2008-09-04 | Snow Brand Milk Prod Co Ltd | 乳酸菌生残性向上剤 |
| AU2008316830B2 (en) | 2007-10-25 | 2016-03-17 | Cempra Pharmaceuticals, Inc. | Process for the preparation of macrolide antibacterial agents |
| CN101981688B (zh) * | 2008-04-02 | 2014-04-02 | Imec公司 | 制造半导体器件的方法以及半导体器件 |
| WO2010048600A1 (en) * | 2008-10-24 | 2010-04-29 | Cempra Pharmaceuticals, Inc. | Methods for treating resistant diseases using triazole containing macrolides |
| US9937194B1 (en) | 2009-06-12 | 2018-04-10 | Cempra Pharmaceuticals, Inc. | Compounds and methods for treating inflammatory diseases |
| US9480679B2 (en) | 2009-09-10 | 2016-11-01 | Cempra Pharmaceuticals, Inc. | Methods for treating malaria, tuberculosis and MAC diseases |
| HRP20160168T1 (hr) | 2010-03-22 | 2016-03-25 | Cempra Pharmaceuticals Inc | Kristalne forme makrolida i njihova uporaba |
| EP2571506B1 (en) | 2010-05-20 | 2017-05-10 | Cempra Pharmaceuticals, Inc. | Processes for preparing macrolides and ketolides and intermediates therefor |
| WO2012007130A1 (en) * | 2010-07-12 | 2012-01-19 | Xellia Pharmaceuticals Aps | Treatment of lung infections by administration of tobramycin by aerolisation |
| KR20130120458A (ko) | 2010-09-10 | 2013-11-04 | 셈프라 파마슈티컬스, 인크. | 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드 |
| BR112014000275A2 (pt) | 2011-07-12 | 2017-04-18 | Cardeas Pharma Inc | formulações aperfeiçoadas de combinações de aminoglicosídeo e fosfomicina e métodos e sistemas para o tratamento de pneumonia associada à ventilação mecânica (pavm) e traqueobronquite associada à ventilação mecânica (vat) |
| US8826904B2 (en) | 2011-07-12 | 2014-09-09 | Cardeas Pharma Corporation | Formulations of aminoglycoside and fosfomycin combinations and methods and systems for treatment of ventilator associated pneumonia (VAP) and ventilator associated tracheal (VAT) bronchitis |
| WO2013148891A1 (en) | 2012-03-27 | 2013-10-03 | Cempra Pharmaceuticals, Inc. | Parenteral formulations for administering macrolide antibiotics |
| GB201208080D0 (en) | 2012-05-09 | 2012-06-20 | Norton Healthcare Ltd | Tobramycin formulation |
| EP2892524B1 (en) | 2012-09-04 | 2020-11-25 | Eleison Pharmaceuticals, LLC | Preventing pulmonary recurrence of cancer with lipid-complexed cisplatin |
| ES2743039T3 (es) | 2012-11-29 | 2020-02-18 | Insmed Inc | Formulaciones de vancomicina estabilizada |
| UA117673C2 (uk) | 2013-01-11 | 2018-09-10 | Кселлія Фармасьютікалз Апс | Поліміксини, композиція, спосіб одержання і спосіб застосування (варіанти) |
| EP2968801B1 (en) | 2013-03-14 | 2018-09-26 | Cempra Pharmaceuticals, Inc. | Methods for treating respiratory diseases and formulations therefor |
| MX356772B (es) | 2013-03-15 | 2018-06-13 | Cempra Pharmaceuticals Inc | Procesos convergentes para la preparacion de agentes antibacterianos macrolidos. |
| EP3466432B1 (en) | 2014-05-15 | 2020-07-08 | Insmed Incorporated | Methods for treating pulmonary non-tuberculous mycobacterial infections |
| EA201692569A1 (ru) | 2014-07-09 | 2017-05-31 | Кселлия Фармасьютикалз Апс | Полимиксины с низкой степенью замещения и композиции, их содержащие |
| ES2721401T3 (es) | 2014-10-03 | 2019-07-31 | Xellia Pharmaceuticals Aps | Dispositivo de inhalación |
| WO2016050928A1 (en) | 2014-10-03 | 2016-04-07 | Xellia Pharmaceuticals Aps | Compositions |
| US10617703B2 (en) | 2014-12-10 | 2020-04-14 | Cmpd Licensing, Llc | Compositions and methods for treating an infection |
| US11278590B2 (en) | 2015-08-05 | 2022-03-22 | Cmpd Licensing, Llc | Compositions and methods for treating nail infections |
| US11446236B2 (en) | 2015-08-05 | 2022-09-20 | Cmpd Licensing, Llc | Topical antimicrobial compositions and methods of formulating the same |
| US11793783B2 (en) | 2015-08-05 | 2023-10-24 | Cmpd Licensing, Llc | Compositions and methods for treating an infection |
| US10898455B2 (en) | 2016-01-07 | 2021-01-26 | Cmpd Licensing, Llc | Urea cream formulations |
| US10898491B2 (en) | 2015-12-18 | 2021-01-26 | Cmpd Licensing, Llc | Compositions and methods for treating an infection |
| US11684567B2 (en) | 2015-08-05 | 2023-06-27 | Cmpd Licensing, Llc | Compositions and methods for treating an infection |
| US11690815B2 (en) | 2015-08-05 | 2023-07-04 | Cmpd Licensing Llc | Hyperkeratotic skin condition treatments and compositions |
| US10525025B2 (en) | 2016-11-17 | 2020-01-07 | Cmpd Licensing, Llc | Compounded compositions and methods for treating pain |
| US9999604B2 (en) | 2016-11-17 | 2018-06-19 | Cmpd Licensing, Llc | Compounded solutions of diclofenac and lidocaine and methods |
| WO2019191627A1 (en) | 2018-03-30 | 2019-10-03 | Insmed Incorporated | Methods for continuous manufacture of liposomal drug products |
| WO2020163416A1 (en) * | 2019-02-05 | 2020-08-13 | Mylan Inc | Devices and methods for tobramycin inhalation treatment |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3993223A (en) | 1974-07-25 | 1976-11-23 | American Home Products Corporation | Dispensing container |
| US4502616A (en) | 1982-01-04 | 1985-03-05 | Health Care Concepts, Inc. | Single use vial |
| GB8801655D0 (en) | 1988-01-26 | 1988-02-24 | Waverley Pharma Ltd | Ampoules |
| EP0326529B1 (en) | 1988-01-28 | 1992-12-30 | Lameplast S.R.L. | A strip of phials for pharmaceuticals, cosmetics and other products |
| GB8802349D0 (en) | 1988-02-03 | 1988-03-02 | Waverley Pharma Ltd | Ampoule with luer |
| DE3916840A1 (de) | 1988-09-21 | 1990-03-29 | Bernd Hansen | Ampulle |
| US5409125A (en) | 1989-12-11 | 1995-04-25 | Aktiebolaget Astra | Unit dose container |
| CA2027690A1 (en) | 1990-10-18 | 1992-04-19 | Christian Laing | Plastic ampul |
| FR2687066A1 (fr) | 1992-02-06 | 1993-08-13 | Oreal | Ampoule autocassable. |
| US5508269A (en) * | 1994-10-19 | 1996-04-16 | Pathogenesis Corporation | Aminoglycoside formulation for aerosolization |
| US5758637A (en) * | 1995-08-31 | 1998-06-02 | Aerogen, Inc. | Liquid dispensing apparatus and methods |
| US6083922A (en) * | 1996-04-02 | 2000-07-04 | Pathogenesis, Corp. | Method and a tobramycin aerosol formulation for treatment prevention and containment of tuberculosis |
| SI20959A (sl) * | 1998-12-17 | 2003-02-28 | Pathogenesis Corporation | Metoda za zdravljenje hudega kroničnega bronhitisa (bronhiektazije) z aerosoliziranimi antibiotiki |
| SE9902627D0 (sv) * | 1999-07-08 | 1999-07-08 | Siemens Elema Ab | Medical nebulizer |
| DE19953317C1 (de) | 1999-11-05 | 2001-02-01 | Pari Gmbh | Inhalationsvernebler |
| PT1320355E (pt) | 2001-05-18 | 2006-08-31 | Chiron Corp | Sistema para administracao de uma formulacao de tobramicina |
-
2002
- 2002-05-17 PT PT02771857T patent/PT1320355E/pt unknown
- 2002-05-17 DK DK02771857T patent/DK1320355T3/da active
- 2002-05-17 ES ES02771857T patent/ES2261735T3/es not_active Expired - Lifetime
- 2002-05-17 JP JP2002590936A patent/JP2004534763A/ja active Pending
- 2002-05-17 EP EP09015943A patent/EP2186508A3/en not_active Withdrawn
- 2002-05-17 CA CA2447600A patent/CA2447600C/en not_active Expired - Fee Related
- 2002-05-17 WO PCT/US2002/015999 patent/WO2002094217A1/en not_active Ceased
- 2002-05-17 US US10/151,701 patent/US20030143162A1/en not_active Abandoned
- 2002-05-17 DE DE60210402T patent/DE60210402T2/de not_active Revoked
- 2002-05-17 AT AT02771857T patent/ATE322249T1/de active
- 2002-05-17 EP EP02771857A patent/EP1320355B1/en not_active Revoked
-
2003
- 2003-12-22 US US10/743,529 patent/US6890907B2/en not_active Expired - Lifetime
-
2004
- 2004-07-01 US US10/883,143 patent/US20040265241A1/en not_active Abandoned
-
2005
- 2005-05-10 US US11/125,670 patent/US20050207987A1/en not_active Abandoned
- 2005-05-10 US US11/126,108 patent/US20050201947A1/en not_active Abandoned
-
2007
- 2007-10-24 US US11/923,486 patent/US7825095B2/en not_active Expired - Lifetime
-
2009
- 2009-08-07 JP JP2009185305A patent/JP2009269923A/ja active Pending
-
2010
- 2010-08-09 AU AU2010210026A patent/AU2010210026A1/en not_active Abandoned
- 2010-09-17 US US12/884,505 patent/US20110005518A1/en not_active Abandoned
-
2011
- 2011-11-14 US US13/295,228 patent/US8507454B2/en not_active Expired - Fee Related
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