JP2004534763A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2004534763A5 JP2004534763A5 JP2002590936A JP2002590936A JP2004534763A5 JP 2004534763 A5 JP2004534763 A5 JP 2004534763A5 JP 2002590936 A JP2002590936 A JP 2002590936A JP 2002590936 A JP2002590936 A JP 2002590936A JP 2004534763 A5 JP2004534763 A5 JP 2004534763A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- less
- composition according
- tobramycin
- spray
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 19
- 239000002647 aminoglycoside antibiotic agent Substances 0.000 claims 12
- 239000007921 spray Substances 0.000 claims 10
- 229960000707 tobramycin Drugs 0.000 claims 10
- NLVFBUXFDBBNBW-PBSUHMDJSA-N tobramycin Chemical compound N[C@@H]1C[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N NLVFBUXFDBBNBW-PBSUHMDJSA-N 0.000 claims 10
- 229940126574 aminoglycoside antibiotic Drugs 0.000 claims 9
- 238000009472 formulation Methods 0.000 claims 9
- 239000000203 mixture Substances 0.000 claims 9
- 239000000443 aerosol Substances 0.000 claims 8
- 239000007864 aqueous solution Substances 0.000 claims 6
- 239000002245 particle Substances 0.000 claims 4
- UCSJYZPVAKXKNQ-HZYVHMACSA-N streptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O UCSJYZPVAKXKNQ-HZYVHMACSA-N 0.000 claims 4
- 201000003883 Cystic fibrosis Diseases 0.000 claims 3
- 229930182566 Gentamicin Natural products 0.000 claims 2
- CEAZRRDELHUEMR-URQXQFDESA-N Gentamicin Chemical compound O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N CEAZRRDELHUEMR-URQXQFDESA-N 0.000 claims 2
- 229930193140 Neomycin Natural products 0.000 claims 2
- 229960004821 amikacin Drugs 0.000 claims 2
- LKCWBDHBTVXHDL-RMDFUYIESA-N amikacin Chemical compound O([C@@H]1[C@@H](N)C[C@H]([C@@H]([C@H]1O)O[C@@H]1[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O1)O)NC(=O)[C@@H](O)CCN)[C@H]1O[C@H](CN)[C@@H](O)[C@H](O)[C@H]1O LKCWBDHBTVXHDL-RMDFUYIESA-N 0.000 claims 2
- 229960002518 gentamicin Drugs 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 229960000318 kanamycin Drugs 0.000 claims 2
- 229930027917 kanamycin Natural products 0.000 claims 2
- SBUJHOSQTJFQJX-NOAMYHISSA-N kanamycin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N SBUJHOSQTJFQJX-NOAMYHISSA-N 0.000 claims 2
- 229930182823 kanamycin A Natural products 0.000 claims 2
- 239000006199 nebulizer Substances 0.000 claims 2
- 229960004927 neomycin Drugs 0.000 claims 2
- ZBGPYVZLYBDXKO-HILBYHGXSA-N netilmycin Chemical compound O([C@@H]1[C@@H](N)C[C@H]([C@@H]([C@H]1O)O[C@@H]1[C@]([C@H](NC)[C@@H](O)CO1)(C)O)NCC)[C@H]1OC(CN)=CC[C@H]1N ZBGPYVZLYBDXKO-HILBYHGXSA-N 0.000 claims 2
- 229960005322 streptomycin Drugs 0.000 claims 2
- 208000032536 Pseudomonas Infections Diseases 0.000 claims 1
- 229960000808 netilmicin Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29223401P | 2001-05-18 | 2001-05-18 | |
| PCT/US2002/015999 WO2002094217A1 (en) | 2001-05-18 | 2002-05-17 | Methods and unit dose formulations for the inhalation administration of aminoglycoside antibiotics |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009185305A Division JP2009269923A (ja) | 2001-05-18 | 2009-08-07 | アミノグリコシド抗生物質の吸入投与のための方法および単位用量処方物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004534763A JP2004534763A (ja) | 2004-11-18 |
| JP2004534763A5 true JP2004534763A5 (enExample) | 2006-01-05 |
Family
ID=23123791
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002590936A Pending JP2004534763A (ja) | 2001-05-18 | 2002-05-17 | アミノグリコシド抗生物質の吸入投与のための方法および単位用量処方物 |
| JP2009185305A Pending JP2009269923A (ja) | 2001-05-18 | 2009-08-07 | アミノグリコシド抗生物質の吸入投与のための方法および単位用量処方物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009185305A Pending JP2009269923A (ja) | 2001-05-18 | 2009-08-07 | アミノグリコシド抗生物質の吸入投与のための方法および単位用量処方物 |
Country Status (11)
| Country | Link |
|---|---|
| US (8) | US20030143162A1 (enExample) |
| EP (2) | EP2186508A3 (enExample) |
| JP (2) | JP2004534763A (enExample) |
| AT (1) | ATE322249T1 (enExample) |
| AU (1) | AU2010210026A1 (enExample) |
| CA (1) | CA2447600C (enExample) |
| DE (1) | DE60210402T2 (enExample) |
| DK (1) | DK1320355T3 (enExample) |
| ES (1) | ES2261735T3 (enExample) |
| PT (1) | PT1320355E (enExample) |
| WO (1) | WO2002094217A1 (enExample) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW465235B (en) | 1998-09-17 | 2001-11-21 | United Video Properties Inc | Electronic program guide with digital storage |
| ES2261735T3 (es) * | 2001-05-18 | 2006-11-16 | Chiron Corporation | Sistema para la administracion de una formulacion de tobramicina. |
| US20040022740A1 (en) * | 2001-07-10 | 2004-02-05 | Baker William R. | Macrolide formulations for inhalation and methods of treatment of endobronchial infections |
| JP2005502653A (ja) * | 2001-08-20 | 2005-01-27 | トランセーヴ・インコーポレーテッド | 肺ガンの治療方法 |
| TWI324518B (en) * | 2001-12-19 | 2010-05-11 | Nektar Therapeutics | Pulmonary delivery of aminoglycosides |
| US7334580B2 (en) * | 2002-05-07 | 2008-02-26 | Smaldone Gerald C | Methods, devices and formulations for targeted endobronchial therapy |
| US7607436B2 (en) * | 2002-05-06 | 2009-10-27 | The Research Foundation Of State University Of New York | Methods, devices and formulations for targeted endobronchial therapy |
| US9186322B2 (en) * | 2002-08-02 | 2015-11-17 | Insmed Incorporated | Platinum aggregates and process for producing the same |
| WO2004054499A2 (en) * | 2002-08-02 | 2004-07-01 | Transave, Inc. | Platinum aggregates and process for producing the same |
| AU2002953095A0 (en) * | 2002-11-29 | 2002-12-19 | Biota Scientific Management Pty Ltd | Novel chemical compounds and their use |
| US7601695B2 (en) | 2003-03-10 | 2009-10-13 | Optimer Pharmaceuticals, Inc. | Antibacterial agents |
| EP1673074B1 (de) * | 2003-10-15 | 2007-01-03 | PARI GmbH Spezialisten für effektive Inhalation | Flüssige zubereitung enthaltend tobramycin |
| US20070065522A1 (en) * | 2004-03-18 | 2007-03-22 | Transave, Inc. | Administration of high potency platinum compound formulations by inhalation |
| AU2005223654A1 (en) * | 2004-03-18 | 2005-09-29 | Transave, Inc. | Administration of cisplatin by inhalation |
| ES2392389T3 (es) | 2004-05-17 | 2012-12-10 | Gilead Sciences, Inc. | Combinación de fosfomicina/aminoglucósido aerosolizada para el tratamiento de las infecciones respiratorias bacterianas |
| AU2005245018A1 (en) * | 2004-05-21 | 2005-12-01 | Transave, Inc. | Treatment of lung diseases and pre-lung disease conditions |
| DK1765288T3 (da) | 2004-06-18 | 2013-02-11 | Novartis Ag | Tobramycinpræparater til behandling af endobronchiale infektioner |
| KR20070089693A (ko) * | 2004-11-08 | 2007-08-31 | 트랜세이브, 인코포레이티드 | 지질-기재 플래티넘 화합물 제형을 복막내 투여하여 암을치료하는 방법 |
| AU2006297289B2 (en) | 2005-09-29 | 2013-03-21 | Novartis Ag | Antibiotic formulations, unit doses, kits, and methods |
| AU2013206401B2 (en) * | 2005-09-29 | 2016-06-23 | Novartis Ag | Antibiotic formulations, unit doses, kits, and methods |
| US20070190182A1 (en) * | 2005-11-08 | 2007-08-16 | Pilkiewicz Frank G | Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally |
| WO2007056236A2 (en) * | 2005-11-08 | 2007-05-18 | Transave, Inc. | Methods of treating cancer with lipid-based platinum compound formulations administered intravenously |
| WO2007056263A2 (en) * | 2005-11-08 | 2007-05-18 | Transave, Inc. | Methods of treating cancer with high potency lipid-based platinum compound formulations administered intravenously |
| US9107824B2 (en) | 2005-11-08 | 2015-08-18 | Insmed Incorporated | Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally |
| US20070122350A1 (en) * | 2005-11-30 | 2007-05-31 | Transave, Inc. | Safe and effective methods of administering therapeutic agents |
| ES2798263T3 (es) | 2005-12-08 | 2020-12-10 | Insmed Inc | Composiciones a base de lípidos de antiinfecciosos para tratar infecciones pulmonares |
| WO2007070875A1 (en) * | 2005-12-15 | 2007-06-21 | Aerosol Science Laboratories, Inc. | Treatment of active infections and related compositions |
| JP2008199905A (ja) * | 2007-02-16 | 2008-09-04 | Snow Brand Milk Prod Co Ltd | 乳酸菌生残性向上剤 |
| AU2008316830B2 (en) | 2007-10-25 | 2016-03-17 | Cempra Pharmaceuticals, Inc. | Process for the preparation of macrolide antibacterial agents |
| CN101981688B (zh) * | 2008-04-02 | 2014-04-02 | Imec公司 | 制造半导体器件的方法以及半导体器件 |
| CN107854477A (zh) | 2008-10-24 | 2018-03-30 | 森普拉制药公司 | 使用含三唑的大环内酯治疗抗性疾病的方法 |
| US9937194B1 (en) | 2009-06-12 | 2018-04-10 | Cempra Pharmaceuticals, Inc. | Compounds and methods for treating inflammatory diseases |
| US9480679B2 (en) | 2009-09-10 | 2016-11-01 | Cempra Pharmaceuticals, Inc. | Methods for treating malaria, tuberculosis and MAC diseases |
| HRP20160168T1 (hr) | 2010-03-22 | 2016-03-25 | Cempra Pharmaceuticals Inc | Kristalne forme makrolida i njihova uporaba |
| BR112012029586A2 (pt) | 2010-05-20 | 2016-08-02 | Cempra Pharmaceuticals Inc | processos para preparar macrolídeos e cetolídeos e intermediários dos mesmos |
| MX336260B (es) * | 2010-07-12 | 2016-01-13 | Xellia Pharmaceuticals Aps | Composiciones para el tratamiento de infecciones de pulmon, formuladas para ser administrables mediante aerolizacion, y que incluyen tobramicina. |
| KR20130120458A (ko) | 2010-09-10 | 2013-11-04 | 셈프라 파마슈티컬스, 인크. | 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드 |
| US8826904B2 (en) | 2011-07-12 | 2014-09-09 | Cardeas Pharma Corporation | Formulations of aminoglycoside and fosfomycin combinations and methods and systems for treatment of ventilator associated pneumonia (VAP) and ventilator associated tracheal (VAT) bronchitis |
| US8603439B2 (en) | 2011-07-12 | 2013-12-10 | Cardeas Pharma Inc. | Formulations of aminoglycoside and fosfomycin combinations and methods and systems for treatment of ventilator associated pneumonia (VAP) and ventilator associated tracheal (VAT) bronchitis |
| WO2013148891A1 (en) | 2012-03-27 | 2013-10-03 | Cempra Pharmaceuticals, Inc. | Parenteral formulations for administering macrolide antibiotics |
| GB201208080D0 (en) | 2012-05-09 | 2012-06-20 | Norton Healthcare Ltd | Tobramycin formulation |
| EP2892524B1 (en) | 2012-09-04 | 2020-11-25 | Eleison Pharmaceuticals, LLC | Preventing pulmonary recurrence of cancer with lipid-complexed cisplatin |
| CA2891487A1 (en) | 2012-11-29 | 2014-06-05 | Insmed Incorporated | Stabilized vancomycin formulations |
| CA2895910C (en) | 2013-01-11 | 2021-12-21 | Xellia Pharmaceuticals Aps | Polymyxins, compositions, methods of making and methods of use |
| WO2014152326A1 (en) * | 2013-03-14 | 2014-09-25 | Cempra Pharmaceuticals, Inc. | Methods for treating respiratory diseases and formulations therefor |
| AU2014233240B2 (en) | 2013-03-15 | 2018-08-09 | Cempra Pharmaceuticals, Inc. | Convergent processes for preparing macrolide antibacterial agents |
| MX384843B (es) | 2014-05-15 | 2025-03-14 | Insmed Inc | Métodos para tratar infecciones pulmonares micobacterianas no tuberculosas. |
| PT3166960T (pt) | 2014-07-09 | 2019-10-25 | Xellia Pharmaceuticals Aps | Polimixinas de baixa substituição e composições das mesmas. |
| CN106794221B (zh) | 2014-10-03 | 2021-12-10 | 埃克斯利亚制药有限公司 | 组合物 |
| PL3200762T3 (pl) | 2014-10-03 | 2019-08-30 | Xellia Pharmaceuticals Aps | Urządzenie do inhalacji |
| US10617703B2 (en) | 2014-12-10 | 2020-04-14 | Cmpd Licensing, Llc | Compositions and methods for treating an infection |
| US11793783B2 (en) | 2015-08-05 | 2023-10-24 | Cmpd Licensing, Llc | Compositions and methods for treating an infection |
| US11278590B2 (en) | 2015-08-05 | 2022-03-22 | Cmpd Licensing, Llc | Compositions and methods for treating nail infections |
| US11446236B2 (en) | 2015-08-05 | 2022-09-20 | Cmpd Licensing, Llc | Topical antimicrobial compositions and methods of formulating the same |
| US10898455B2 (en) | 2016-01-07 | 2021-01-26 | Cmpd Licensing, Llc | Urea cream formulations |
| US11684567B2 (en) | 2015-08-05 | 2023-06-27 | Cmpd Licensing, Llc | Compositions and methods for treating an infection |
| US10898491B2 (en) | 2015-12-18 | 2021-01-26 | Cmpd Licensing, Llc | Compositions and methods for treating an infection |
| US11690815B2 (en) | 2015-08-05 | 2023-07-04 | Cmpd Licensing Llc | Hyperkeratotic skin condition treatments and compositions |
| US9999604B2 (en) | 2016-11-17 | 2018-06-19 | Cmpd Licensing, Llc | Compounded solutions of diclofenac and lidocaine and methods |
| US10525025B2 (en) | 2016-11-17 | 2020-01-07 | Cmpd Licensing, Llc | Compounded compositions and methods for treating pain |
| EP3773505B1 (en) | 2018-03-30 | 2026-04-29 | Insmed Incorporated | Methods for continuous manufacture of liposomal drug products |
| EP3787602A4 (en) | 2018-05-02 | 2022-03-23 | Insmed Incorporated | PROCESS FOR THE MANUFACTURE OF LIPOSOMAL DRUG FORMULATIONS |
| WO2020163416A1 (en) * | 2019-02-05 | 2020-08-13 | Mylan Inc | Devices and methods for tobramycin inhalation treatment |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3993223A (en) | 1974-07-25 | 1976-11-23 | American Home Products Corporation | Dispensing container |
| US4502616A (en) | 1982-01-04 | 1985-03-05 | Health Care Concepts, Inc. | Single use vial |
| GB8801655D0 (en) | 1988-01-26 | 1988-02-24 | Waverley Pharma Ltd | Ampoules |
| EP0326529B1 (en) | 1988-01-28 | 1992-12-30 | Lameplast S.R.L. | A strip of phials for pharmaceuticals, cosmetics and other products |
| GB8802349D0 (en) | 1988-02-03 | 1988-03-02 | Waverley Pharma Ltd | Ampoule with luer |
| DE3916840A1 (de) | 1988-09-21 | 1990-03-29 | Bernd Hansen | Ampulle |
| US5409125A (en) | 1989-12-11 | 1995-04-25 | Aktiebolaget Astra | Unit dose container |
| CA2027690A1 (en) | 1990-10-18 | 1992-04-19 | Christian Laing | Plastic ampul |
| FR2687066A1 (fr) | 1992-02-06 | 1993-08-13 | Oreal | Ampoule autocassable. |
| US5508269A (en) | 1994-10-19 | 1996-04-16 | Pathogenesis Corporation | Aminoglycoside formulation for aerosolization |
| US5758637A (en) * | 1995-08-31 | 1998-06-02 | Aerogen, Inc. | Liquid dispensing apparatus and methods |
| US6083922A (en) * | 1996-04-02 | 2000-07-04 | Pathogenesis, Corp. | Method and a tobramycin aerosol formulation for treatment prevention and containment of tuberculosis |
| CN1348377A (zh) | 1998-12-17 | 2002-05-08 | 希龙公司 | 用气溶胶化的抗生素治疗严重慢性支气管炎(支气管扩张症)的方法 |
| SE9902627D0 (sv) * | 1999-07-08 | 1999-07-08 | Siemens Elema Ab | Medical nebulizer |
| DE19953317C1 (de) | 1999-11-05 | 2001-02-01 | Pari Gmbh | Inhalationsvernebler |
| ES2261735T3 (es) | 2001-05-18 | 2006-11-16 | Chiron Corporation | Sistema para la administracion de una formulacion de tobramicina. |
-
2002
- 2002-05-17 ES ES02771857T patent/ES2261735T3/es not_active Expired - Lifetime
- 2002-05-17 DK DK02771857T patent/DK1320355T3/da active
- 2002-05-17 AT AT02771857T patent/ATE322249T1/de active
- 2002-05-17 PT PT02771857T patent/PT1320355E/pt unknown
- 2002-05-17 EP EP09015943A patent/EP2186508A3/en not_active Withdrawn
- 2002-05-17 DE DE60210402T patent/DE60210402T2/de not_active Revoked
- 2002-05-17 WO PCT/US2002/015999 patent/WO2002094217A1/en not_active Ceased
- 2002-05-17 EP EP02771857A patent/EP1320355B1/en not_active Revoked
- 2002-05-17 US US10/151,701 patent/US20030143162A1/en not_active Abandoned
- 2002-05-17 CA CA2447600A patent/CA2447600C/en not_active Expired - Fee Related
- 2002-05-17 JP JP2002590936A patent/JP2004534763A/ja active Pending
-
2003
- 2003-12-22 US US10/743,529 patent/US6890907B2/en not_active Expired - Lifetime
-
2004
- 2004-07-01 US US10/883,143 patent/US20040265241A1/en not_active Abandoned
-
2005
- 2005-05-10 US US11/125,670 patent/US20050207987A1/en not_active Abandoned
- 2005-05-10 US US11/126,108 patent/US20050201947A1/en not_active Abandoned
-
2007
- 2007-10-24 US US11/923,486 patent/US7825095B2/en not_active Expired - Lifetime
-
2009
- 2009-08-07 JP JP2009185305A patent/JP2009269923A/ja active Pending
-
2010
- 2010-08-09 AU AU2010210026A patent/AU2010210026A1/en not_active Abandoned
- 2010-09-17 US US12/884,505 patent/US20110005518A1/en not_active Abandoned
-
2011
- 2011-11-14 US US13/295,228 patent/US8507454B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR101357508B1 (ko) | 투약 및 건식 분무용 장치 | |
| KR102012418B1 (ko) | 에어로졸화에 의한 토브라마이신의 투여에 의한 폐 감염의 치료 | |
| AU642037B2 (en) | Device for mouth-inhaling aerosol medicaments | |
| CA2464250C (en) | Kit for the preparation of a pharmaceutical composition | |
| EP2186508A3 (en) | Methods and unit dose formulations for the inhalation administration of aminoglycoside antibiotics | |
| JP2011520911A5 (enExample) | ||
| JP2009269923A5 (enExample) | ||
| CA2406119A1 (en) | Pharmaceutical formulations for dry powder inhalers in the form of hard-pellets | |
| HU220290B (hu) | Inhaláló készülék és eljárás száraz por alakú aktív anyag inhalálására | |
| CA2468958A1 (en) | Pulmonary delivery of aminoglycosides | |
| AU2001275368A1 (en) | Highly efficient delivery of a large therapeutic mass aerosol | |
| JP2008536546A5 (enExample) | ||
| JP2003525081A5 (enExample) | ||
| CA2425489A1 (en) | Therapeutic use of aerosolized s-nitrosoglutathione in cystic fibrosis | |
| CA2564546A1 (en) | Aerosolized fosfomycin/aminoglycoside combination for the treatment of bacterial respiratory infections | |
| TNSN06277A1 (en) | Pharmaceutical formulations for dry powder inhalers comprising a low-dosage strength active ingredient | |
| Subramani et al. | The role of pulmonary drug delivery in modern therapeutics: an overview | |
| US10471083B2 (en) | Formulations of aminoglycoside and fosfomycin in combination for treatment of ventilator associated pneumonia (VAP) and ventilator associated tracheal (VAT) bronchitis | |
| JP2024531784A (ja) | トブラマイシン吸入溶液を含む薬学的組立品及びその使用 | |
| US20130291860A1 (en) | Method For Treating Cystic Fibrosis with Inhaled Denufosol | |
| US20210046258A1 (en) | Method and apparatus for producing fine concentrated aerosol | |
| JP2005531604A5 (enExample) | ||
| CZ287114B6 (en) | Therapeutic preparation in the form of aerosol and use of gas mixture | |
| KR20230035518A (ko) | 선천적 면역 반응을 생성하기 위한 퀴닌과 그의 용도 | |
| WO2021158851A1 (en) | Pharmaceutical formulation containing remdesivir |