CA2447600C - Methods and unit dose formulations for the inhalation administration of aminoglycoside antibiotics - Google Patents
Methods and unit dose formulations for the inhalation administration of aminoglycoside antibiotics Download PDFInfo
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- CA2447600C CA2447600C CA2447600A CA2447600A CA2447600C CA 2447600 C CA2447600 C CA 2447600C CA 2447600 A CA2447600 A CA 2447600A CA 2447600 A CA2447600 A CA 2447600A CA 2447600 C CA2447600 C CA 2447600C
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- tobi
- tobramycin
- dose
- patients
- treatment
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Classifications
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- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
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- General Chemical & Material Sciences (AREA)
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- Communicable Diseases (AREA)
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- Otolaryngology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| PCT/US2002/015999 WO2002094217A1 (en) | 2001-05-18 | 2002-05-17 | Methods and unit dose formulations for the inhalation administration of aminoglycoside antibiotics |
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| CA2447600C true CA2447600C (en) | 2015-10-20 |
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| US7607436B2 (en) * | 2002-05-06 | 2009-10-27 | The Research Foundation Of State University Of New York | Methods, devices and formulations for targeted endobronchial therapy |
| US7334580B2 (en) * | 2002-05-07 | 2008-02-26 | Smaldone Gerald C | Methods, devices and formulations for targeted endobronchial therapy |
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| US9107824B2 (en) | 2005-11-08 | 2015-08-18 | Insmed Incorporated | Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally |
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| JP2014523909A (ja) | 2011-07-12 | 2014-09-18 | カーディアス ファーマ コーポレイション | 人工呼吸器関連肺炎（ｖａｐ）及び人工呼吸器関連気管（ｖａｔ）気管支炎の治療のためのアミカシンとホスホマイシンの組み合わせの製剤並びに方法及びシステム |
| CA2868262A1 (en) | 2012-03-27 | 2013-10-03 | Cempra Pharmaceuticals, Inc. | Parenteral formulations for administering macrolide antibiotics |
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| DK2892524T3 (da) | 2012-09-04 | 2021-01-25 | Eleison Pharmaceuticals LLC | Forebyggelse af pulmonalt kræfttilbagefald med lipid-komplekseret cisplatin |
| WO2014085526A1 (en) | 2012-11-29 | 2014-06-05 | Insmed Incorporated | Stabilized vancomycin formulations |
| JP6316846B2 (ja) | 2013-01-11 | 2018-04-25 | クセリア ファーマシューティカルズ エーピーエスＸｅｌｌｉａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ ＡｐＳ | ポリミキシン含有組成物 |
| HK1217665A1 (zh) * | 2013-03-14 | 2017-01-20 | 森普拉制药公司 | 用於治療呼吸道疾病的方法及其製劑 |
| HK1218864A1 (zh) | 2013-03-15 | 2017-03-17 | 森普拉制药公司 | 用於制备大环内酯抗菌剂的收敛方法 |
| KR102447412B1 (ko) | 2014-05-15 | 2022-09-23 | 인스메드 인코포레이티드 | 폐의 비-결핵성 마이코박테리아 감염을 치료하기 위한 방법 |
| EP3166960B1 (en) | 2014-07-09 | 2019-08-07 | Xellia Pharmaceuticals ApS | Low substituted polymyxins and compositions thereof |
| HUE052028T2 (hu) | 2014-10-03 | 2021-04-28 | Xellia Pharmaceuticals Aps | Kompozíciók |
| ES2721401T3 (es) | 2014-10-03 | 2019-07-31 | Xellia Pharmaceuticals Aps | Dispositivo de inhalación |
| US10617703B2 (en) | 2014-12-10 | 2020-04-14 | Cmpd Licensing, Llc | Compositions and methods for treating an infection |
| US11690815B2 (en) | 2015-08-05 | 2023-07-04 | Cmpd Licensing Llc | Hyperkeratotic skin condition treatments and compositions |
| US10898455B2 (en) | 2016-01-07 | 2021-01-26 | Cmpd Licensing, Llc | Urea cream formulations |
| US11278590B2 (en) | 2015-08-05 | 2022-03-22 | Cmpd Licensing, Llc | Compositions and methods for treating nail infections |
| US11446236B2 (en) | 2015-08-05 | 2022-09-20 | Cmpd Licensing, Llc | Topical antimicrobial compositions and methods of formulating the same |
| US11793783B2 (en) | 2015-08-05 | 2023-10-24 | Cmpd Licensing, Llc | Compositions and methods for treating an infection |
| US10898491B2 (en) | 2015-12-18 | 2021-01-26 | Cmpd Licensing, Llc | Compositions and methods for treating an infection |
| US11684567B2 (en) | 2015-08-05 | 2023-06-27 | Cmpd Licensing, Llc | Compositions and methods for treating an infection |
| US9999604B2 (en) | 2016-11-17 | 2018-06-19 | Cmpd Licensing, Llc | Compounded solutions of diclofenac and lidocaine and methods |
| US10525025B2 (en) | 2016-11-17 | 2020-01-07 | Cmpd Licensing, Llc | Compounded compositions and methods for treating pain |
| JP7460534B2 (ja) | 2018-03-30 | 2024-04-02 | インスメッド インコーポレイテッド | リポソーム医薬品の連続製造方法 |
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| US3993223A (en) | 1974-07-25 | 1976-11-23 | American Home Products Corporation | Dispensing container |
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| GB8801655D0 (en) | 1988-01-26 | 1988-02-24 | Waverley Pharma Ltd | Ampoules |
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| GB8802349D0 (en) | 1988-02-03 | 1988-03-02 | Waverley Pharma Ltd | Ampoule with luer |
| DE3916840A1 (de) | 1988-09-21 | 1990-03-29 | Bernd Hansen | Ampulle |
| US5409125A (en) | 1989-12-11 | 1995-04-25 | Aktiebolaget Astra | Unit dose container |
| CA2027690A1 (en) | 1990-10-18 | 1992-04-19 | Christian Laing | Plastic ampul |
| FR2687066A1 (fr) | 1992-02-06 | 1993-08-13 | Oreal | Ampoule autocassable. |
| US5508269A (en) * | 1994-10-19 | 1996-04-16 | Pathogenesis Corporation | Aminoglycoside formulation for aerosolization |
| US5758637A (en) * | 1995-08-31 | 1998-06-02 | Aerogen, Inc. | Liquid dispensing apparatus and methods |
| US6083922A (en) * | 1996-04-02 | 2000-07-04 | Pathogenesis, Corp. | Method and a tobramycin aerosol formulation for treatment prevention and containment of tuberculosis |
| CZ20012147A3 (cs) * | 1998-12-17 | 2003-01-15 | Chiron Corporation | Farmaceutický prostředek ve formě suchého práąku nebo rozpráąeného aerosolového prostředku pro léčení chronické bronchitidy |
| SE9902627D0 (sv) * | 1999-07-08 | 1999-07-08 | Siemens Elema Ab | Medical nebulizer |
| DE19953317C1 (de) | 1999-11-05 | 2001-02-01 | Pari Gmbh | Inhalationsvernebler |
| CA2447600C (en) | 2001-05-18 | 2015-10-20 | Chiron Corporation | Methods and unit dose formulations for the inhalation administration of aminoglycoside antibiotics |
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2002
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- 2002-05-17 DE DE60210402T patent/DE60210402T2/de not_active Revoked
- 2002-05-17 DK DK02771857T patent/DK1320355T3/da active
- 2002-05-17 PT PT02771857T patent/PT1320355E/pt unknown
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- 2002-05-17 US US10/151,701 patent/US20030143162A1/en not_active Abandoned
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2005
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2009
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2011
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Also Published As
| Publication number | Publication date |
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| US20030143162A1 (en) | 2003-07-31 |
| EP2186508A3 (en) | 2010-08-25 |
| JP2009269923A (ja) | 2009-11-19 |
| AU2010210026A1 (en) | 2010-09-02 |
| US20120101055A1 (en) | 2012-04-26 |
| JP2004534763A (ja) | 2004-11-18 |
| EP1320355A1 (en) | 2003-06-25 |
| ES2261735T3 (es) | 2006-11-16 |
| EP1320355B1 (en) | 2006-04-05 |
| US20050207987A1 (en) | 2005-09-22 |
| US20040265241A1 (en) | 2004-12-30 |
| WO2002094217A1 (en) | 2002-11-28 |
| US20080095717A1 (en) | 2008-04-24 |
| DE60210402D1 (de) | 2006-05-18 |
| DE60210402T2 (de) | 2006-12-07 |
| US7825095B2 (en) | 2010-11-02 |
| US20040131555A1 (en) | 2004-07-08 |
| US20110005518A1 (en) | 2011-01-13 |
| PT1320355E (pt) | 2006-08-31 |
| US6890907B2 (en) | 2005-05-10 |
| US20050201947A1 (en) | 2005-09-15 |
| EP2186508A2 (en) | 2010-05-19 |
| ATE322249T1 (de) | 2006-04-15 |
| CA2447600A1 (en) | 2002-11-28 |
| US8507454B2 (en) | 2013-08-13 |
| DK1320355T3 (da) | 2006-07-31 |
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