JP2004534093A - フルベストラントの筋肉内投与用の医薬製剤 - Google Patents

フルベストラントの筋肉内投与用の医薬製剤 Download PDF

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Publication number
JP2004534093A
JP2004534093A JP2003511869A JP2003511869A JP2004534093A JP 2004534093 A JP2004534093 A JP 2004534093A JP 2003511869 A JP2003511869 A JP 2003511869A JP 2003511869 A JP2003511869 A JP 2003511869A JP 2004534093 A JP2004534093 A JP 2004534093A
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JP
Japan
Prior art keywords
formulation
weight
volume
fulvestrant
carrier
Prior art date
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Pending
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JP2003511869A
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English (en)
Japanese (ja)
Inventor
ケイヒル，ジュリー・ケイ
ジェラート，ポール・リチャード
アーヴィング，アラン・マーシャル
Original Assignee
アストラゼネカ アクチボラグ
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Priority claimed from GBGB0116619.8A external-priority patent/GB0116619D0/en
Application filed by アストラゼネカ アクチボラグ filed Critical アストラゼネカ アクチボラグ
Publication of JP2004534093A publication Critical patent/JP2004534093A/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
JP2003511869A 2001-07-07 2002-07-03 フルベストラントの筋肉内投与用の医薬製剤 Pending JP2004534093A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0116619.8A GB0116619D0 (en) 2001-07-07 2001-07-07 Formulation
US31571101P 2001-08-30 2001-08-30
PCT/GB2002/003092 WO2003006064A1 (en) 2001-07-07 2002-07-03 Pharmaceutical formulation for the intramuscular administration of fulvestrant

Publications (1)

Publication Number Publication Date
JP2004534093A true JP2004534093A (ja) 2004-11-11

Family

ID=26246290

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003511869A Pending JP2004534093A (ja) 2001-07-07 2002-07-03 フルベストラントの筋肉内投与用の医薬製剤

Country Status (15)

Country Link
EP (1) EP1406662A1 (hu)
JP (1) JP2004534093A (hu)
CN (1) CN1553815A (hu)
AR (1) AR037138A1 (hu)
BR (1) BR0210898A (hu)
CA (1) CA2453111A1 (hu)
CO (1) CO5560585A2 (hu)
HU (1) HUP0400115A3 (hu)
IL (1) IL159576A0 (hu)
IS (1) IS7097A (hu)
MX (1) MXPA04000028A (hu)
NO (1) NO20040047L (hu)
PL (1) PL367624A1 (hu)
RU (1) RU2004102393A (hu)
WO (1) WO2003006064A1 (hu)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015511606A (ja) * 2012-03-31 2015-04-20 リポント ファーマシューティカルズ インコーポレイテッド 乳酸エステルをベースとするフルベストラント又はその誘導体の油性製剤およびその製造方法
WO2017175810A1 (ja) * 2016-04-06 2017-10-12 富士フイルム株式会社 医薬組成物
JP2019516789A (ja) * 2016-05-06 2019-06-20 イーグル ファーマスーティカルズ、インク． フルベストラント配合物およびその使用方法
US10668083B2 (en) 2016-05-31 2020-06-02 Fujifilm Corporation Pharmaceutical composition
JP2021502362A (ja) * 2017-11-08 2021-01-28 イーグル ファーマスーティカルズ、インク． フルベストラント製剤とその使用方法
JP2023504867A (ja) * 2019-12-11 2023-02-07 上海博志研新薬物技術有限公司 フルベストラント医薬組成物、その調製方法及び応用
JP7497902B2 (ja) 2019-12-11 2024-06-11 上海雲晟研新生物科技有限公司 フルベストラント医薬組成物、その調製方法及び応用

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0000313D0 (en) 2000-01-10 2000-03-01 Astrazeneca Uk Ltd Formulation
US8586092B2 (en) 2009-08-31 2013-11-19 Xi'an Libang Pharmaceutical Technology Co., Ltd. Fulvestrant nanosphere/microsphere and preparative method and use thereof
CN102600064A (zh) * 2012-03-31 2012-07-25 西安力邦制药有限公司 氟维司群或其衍生物缓释制剂及其制备方法
CN102600065B (zh) * 2012-03-31 2014-08-13 莱普德制药有限公司 一种氟维司群或其衍生物油性制剂及其制备方法
US9271990B2 (en) 2014-02-14 2016-03-01 Fresenius Kabi Usa, Llc Fulvestrant formulations
US11590077B2 (en) 2016-05-06 2023-02-28 Eagle Pharmaceuticals, Inc. Fulvestrant formulations and methods of their use
US20210169897A1 (en) * 2017-12-07 2021-06-10 Nevakar Inc. Concentrated Fulvestrant Compositions
CN111465398A (zh) * 2018-01-31 2020-07-28 富士胶片株式会社 注射用制剂的制造方法
CN111481559B (zh) * 2019-01-25 2021-10-08 江苏恒瑞医药股份有限公司 一种高浓度的氟维司群组合物及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8813353D0 (en) * 1988-06-06 1988-07-13 Ici Plc Therapeutic product
GB9525194D0 (en) * 1995-12-12 1996-02-07 Zeneca Ltd Pharmaceutical composition
GB0000313D0 (en) * 2000-01-10 2000-03-01 Astrazeneca Uk Ltd Formulation
GB0008172D0 (en) * 2000-04-05 2000-05-24 Astrazeneca Ab Therapy

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015511606A (ja) * 2012-03-31 2015-04-20 リポント ファーマシューティカルズ インコーポレイテッド 乳酸エステルをベースとするフルベストラント又はその誘導体の油性製剤およびその製造方法
US10568890B2 (en) 2012-03-31 2020-02-25 Xi'an Libang Pharmaceutical Co., Ltd Lactate-based fulvestrant or fulvestrant derivative oily preparation and preparation method thereof
WO2017175810A1 (ja) * 2016-04-06 2017-10-12 富士フイルム株式会社 医薬組成物
JPWO2017175810A1 (ja) * 2016-04-06 2018-12-20 富士フイルム株式会社 医薬組成物
US10772895B2 (en) 2016-04-06 2020-09-15 Fujifilm Corporation Pharmaceutical composition
JP2019516789A (ja) * 2016-05-06 2019-06-20 イーグル ファーマスーティカルズ、インク． フルベストラント配合物およびその使用方法
US10668083B2 (en) 2016-05-31 2020-06-02 Fujifilm Corporation Pharmaceutical composition
JP2021502362A (ja) * 2017-11-08 2021-01-28 イーグル ファーマスーティカルズ、インク． フルベストラント製剤とその使用方法
JP7220712B2 (ja) 2017-11-08 2023-02-10 イーグル ファーマスーティカルズ、インク． フルベストラント製剤とその使用方法
JP2023504867A (ja) * 2019-12-11 2023-02-07 上海博志研新薬物技術有限公司 フルベストラント医薬組成物、その調製方法及び応用
JP7497902B2 (ja) 2019-12-11 2024-06-11 上海雲晟研新生物科技有限公司 フルベストラント医薬組成物、その調製方法及び応用

Also Published As

Publication number Publication date
AR037138A1 (es) 2004-10-27
NO20040047L (no) 2004-02-23
CO5560585A2 (es) 2005-09-30
WO2003006064A1 (en) 2003-01-23
EP1406662A1 (en) 2004-04-14
HUP0400115A2 (hu) 2004-06-28
HUP0400115A3 (en) 2005-11-28
BR0210898A (pt) 2004-06-22
RU2004102393A (ru) 2005-03-27
CA2453111A1 (en) 2003-01-23
IL159576A0 (en) 2004-06-01
MXPA04000028A (es) 2004-05-21
CN1553815A (zh) 2004-12-08
IS7097A (is) 2004-01-05
PL367624A1 (en) 2005-03-07

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