JP2004533242A5 - - Google Patents

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Publication number
JP2004533242A5
JP2004533242A5 JP2002585632A JP2002585632A JP2004533242A5 JP 2004533242 A5 JP2004533242 A5 JP 2004533242A5 JP 2002585632 A JP2002585632 A JP 2002585632A JP 2002585632 A JP2002585632 A JP 2002585632A JP 2004533242 A5 JP2004533242 A5 JP 2004533242A5
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JP
Japan
Prior art keywords
cell
organ
tissue
epitope
human
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002585632A
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English (en)
Japanese (ja)
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JP2004533242A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2002/013564 external-priority patent/WO2002088351A1/en
Publication of JP2004533242A publication Critical patent/JP2004533242A/ja
Publication of JP2004533242A5 publication Critical patent/JP2004533242A5/ja
Pending legal-status Critical Current

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JP2002585632A 2001-04-30 2002-04-29 異種移植のための改変された器官および細胞 Pending JP2004533242A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US28768401P 2001-04-30 2001-04-30
US30060401P 2001-06-22 2001-06-22
US33387601P 2001-11-28 2001-11-28
PCT/US2002/013564 WO2002088351A1 (en) 2001-04-30 2002-04-29 Modified organs and cells for xenotransplantation

Publications (2)

Publication Number Publication Date
JP2004533242A JP2004533242A (ja) 2004-11-04
JP2004533242A5 true JP2004533242A5 (https=) 2006-08-24

Family

ID=27403740

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002585632A Pending JP2004533242A (ja) 2001-04-30 2002-04-29 異種移植のための改変された器官および細胞

Country Status (7)

Country Link
US (3) US7166278B2 (https=)
EP (1) EP1383889B1 (https=)
JP (1) JP2004533242A (https=)
AU (1) AU2002308533B2 (https=)
CA (1) CA2445945A1 (https=)
ES (1) ES2530872T3 (https=)
WO (1) WO2002088351A1 (https=)

Families Citing this family (25)

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EP1639083A4 (en) * 2003-06-06 2008-05-28 Univ Pittsburgh GENE OF CMP-N-ACETYLNEURAMIC ACID HYDROXYLASE FROM PIG
CA2533259C (en) * 2003-07-21 2014-01-28 Lifecell Corporation Acellular tissue matrices made from galactose .alpha.-1,3-galactose-deficient tissue
AU2005223617A1 (en) 2004-03-17 2005-09-29 Revivicor, Inc. Tissue products from animals lacking functional alpha 1,3 galactosyl transferase
JP2006129736A (ja) * 2004-11-02 2006-05-25 Nippon Dobutsu Kogaku Kenkyusho:Kk 異種移植用豚細胞、その選抜方法及び異種移植用豚
US20060147429A1 (en) * 2004-12-30 2006-07-06 Paul Diamond Facilitated cellular reconstitution of organs and tissues
WO2006074373A2 (en) * 2005-01-06 2006-07-13 Crosscart, Inc. Immunochemically modified and sterilized xenografts and allografts
EP1893756B1 (en) * 2005-06-08 2015-08-12 The Regents of The University of California Elimination of n-glycolylneuraminic acid from mammalian products for human use
FI20055398A0 (fi) 2005-07-08 2005-07-08 Suomen Punainen Risti Veripalv Menetelmä solupopulaatioiden evaluoimiseksi
FI20075030A0 (fi) 2007-01-18 2007-01-18 Suomen Punainen Risti Veripalv Menetelmä solujen modifioimiseksi
KR101149475B1 (ko) 2007-11-30 2012-05-25 한국생명공학연구원 이종 장기 이식용 미니 복제돼지 생산을 위한 유전자 조작된 세포주 및 그의 생산방법
EP2166085A1 (en) 2008-07-16 2010-03-24 Suomen Punainen Risti Veripalvelu Divalent modified cells
EP2324110A4 (en) * 2008-09-09 2013-01-09 Univ California ELIMINATION OF A CONTAMINATING NON-HUMAN SIALIC ACID BY METABOLISM COMPETITION
US9420770B2 (en) 2009-12-01 2016-08-23 Indiana University Research & Technology Corporation Methods of modulating thrombocytopenia and modified transgenic pigs
KR101276801B1 (ko) * 2011-01-21 2013-06-19 한화엘앤씨 주식회사 ｓＴＮＦＲ1-Ｆｃ 유전자를 발현하는 형질전환 돼지 및 이의 용도
WO2013151649A1 (en) 2012-04-04 2013-10-10 Sialix Inc Glycan-interacting compounds
US20140115728A1 (en) 2012-10-24 2014-04-24 A. Joseph Tector Double knockout (gt/cmah-ko) pigs, organs and tissues
WO2015066668A1 (en) 2013-11-04 2015-05-07 Lifecell Corporation Methods of removing alpha-galactose
CA2965550A1 (en) 2014-10-22 2016-04-28 Indiana University Research & Technology Corporation Triple transgenic pigs suitable for xenograft
FI3218005T3 (fi) 2014-11-12 2023-03-31 Seagen Inc Glykaanin kanssa vuorovaikutteisia yhdisteitä ja käyttömenetelmiä
US9879087B2 (en) 2014-11-12 2018-01-30 Siamab Therapeutics, Inc. Glycan-interacting compounds and methods of use
CN116059378A (zh) 2014-12-10 2023-05-05 明尼苏达大学董事会 用于治疗疾病的遗传修饰的细胞、组织和器官
CA3002097A1 (en) 2015-11-12 2017-05-18 Siamab Therapeutics, Inc. Glycan-interacting compounds and methods of use
WO2018094143A1 (en) 2016-11-17 2018-05-24 Siamab Therapeutics, Inc. Glycan-interacting compounds and methods of use
WO2018160909A1 (en) 2017-03-03 2018-09-07 Siamab Therapeutics, Inc. Glycan-interacting compounds and methods of use
KR102746223B1 (ko) 2017-04-20 2024-12-27 이제네시스, 인크. 유전자 변형 동물의 생성 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03255028A (ja) 1990-03-01 1991-11-13 Imeeji Meekaa:Kk 免疫抑制剤
WO1992017189A1 (en) 1991-03-29 1992-10-15 The Regents Of The University Of California Gangliosides with immunosuppressive activity
US6228631B1 (en) * 1992-10-22 2001-05-08 New York Blood Center, Inc. Recombinant α-N-acetylgalactosaminidase enzyme and cDNA encoding said enzyme
US5330974A (en) * 1993-03-01 1994-07-19 Fibratek, Inc. Therapeutic fibrinogen compositions
US6331658B1 (en) * 1993-04-20 2001-12-18 Integris Baptist Medical Center, Inc. Genetically engineered mammals for use as organ donors
JPH09508277A (ja) 1994-01-27 1997-08-26 ブレサゲン リミテッド ヒト異種移植における超急性拒絶の管理のための物質及び方法
US6166288A (en) * 1995-09-27 2000-12-26 Nextran Inc. Method of producing transgenic animals for xenotransplantation expressing both an enzyme masking or reducing the level of the gal epitope and a complement inhibitor
US6245890B1 (en) * 1999-03-26 2001-06-12 New York Blood Center, Inc. Porcine protein and uses thereof

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