JP2009509979A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009509979A5 JP2009509979A5 JP2008532546A JP2008532546A JP2009509979A5 JP 2009509979 A5 JP2009509979 A5 JP 2009509979A5 JP 2008532546 A JP2008532546 A JP 2008532546A JP 2008532546 A JP2008532546 A JP 2008532546A JP 2009509979 A5 JP2009509979 A5 JP 2009509979A5
- Authority
- JP
- Japan
- Prior art keywords
- serpin
- granzyme
- cell
- composition
- tissue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72179905P | 2005-09-29 | 2005-09-29 | |
| PCT/CA2006/001582 WO2007036028A1 (en) | 2005-09-29 | 2006-09-26 | Compositions for and methods of granzyme b inhibition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009509979A JP2009509979A (ja) | 2009-03-12 |
| JP2009509979A5 true JP2009509979A5 (https=) | 2010-11-18 |
Family
ID=37899312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008532546A Pending JP2009509979A (ja) | 2005-09-29 | 2006-09-26 | グランザイムｂ阻害のための組成物および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20070104699A1 (https=) |
| EP (1) | EP1940458A4 (https=) |
| JP (1) | JP2009509979A (https=) |
| AU (1) | AU2006297036A1 (https=) |
| CA (1) | CA2623957A1 (https=) |
| WO (1) | WO2007036028A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7951776B2 (en) * | 2006-09-01 | 2011-05-31 | American Type Culture Collection | Methods for treatment of type 1 diabetes |
| US8426149B2 (en) | 2007-10-01 | 2013-04-23 | The University Of British Columbia | Granzyme A and granzyme B diagnostics |
| CA2739523A1 (en) | 2007-10-01 | 2009-04-09 | The University Of British Columbia | Treatment of dissection, aneurysm, and atherosclerosis using granzyme b inhibitors |
| CA2819810A1 (en) * | 2010-12-06 | 2012-06-14 | The University Of British Columbia | Granzyme b inhibitor compositions, methods and uses for promoting wound healing |
| JP7194595B2 (ja) | 2016-07-01 | 2022-12-22 | ザ ジェネラル ホスピタル コーポレイション | グランザイムｂを指向するイメージングおよび治療 |
| CN119345374A (zh) * | 2024-10-31 | 2025-01-24 | 南通大学 | 靶向颗粒酶b在帕金森病神经元退变免疫治疗药物中的应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5674708A (en) * | 1989-06-23 | 1997-10-07 | Trustees Of The University Of Pennsylvania | α-1-antichymotrypsin analogues having elastase inhibitory activity |
| US5266465A (en) * | 1989-06-23 | 1993-11-30 | The Trustees Of The University Of Pennsylvania | α-1-antichymotrypsin, analogues and methods of production |
| US5612194A (en) * | 1989-06-23 | 1997-03-18 | Trustees Of The University Of Pennsylvania | Methods of producing effective recombinant serine protease inhibitors and uses of these inhibitors |
| DE10121255A1 (de) * | 2001-04-30 | 2002-11-07 | Switch Biotech Ag | Verwendung von alpha 1-Antichymotrypsin Polypeptiden oder diese kodierende Nukleinsäuren, oder einer ein ACT Polypeptid oder diese kodierende Nukleinsäure exprimierende Zelle, zur Behandlung und/oder Prävention von diabetes-assoziierten und/oder arteriellen schlecht heilenden Wunden und zur Identifizierung von pharmakologisch aktiven Substanzen |
| EP1474093A4 (en) * | 2002-02-04 | 2005-02-16 | Merck & Co Inc | Granzyme B INHIBITORS |
| AU2003275173A1 (en) * | 2002-09-25 | 2004-04-19 | Board Of Regents, The University Of Texas System | Endogenous granzyme b in human non-hematopoietic cells |
| JP2005120070A (ja) * | 2003-03-10 | 2005-05-12 | Taisho Pharmaceut Co Ltd | エラスターゼ遊離抑制剤及び脳梗塞治療薬 |
| US20070116694A1 (en) * | 2003-06-18 | 2007-05-24 | Daiichi Pharmaceutical Co., Ltd. | Inhibitor of interaction of granzyme b with golgin-160 |
| JP2005060379A (ja) * | 2003-07-31 | 2005-03-10 | Dainippon Pharmaceut Co Ltd | 複素環式化合物からなる医薬 |
| SE0302487D0 (sv) * | 2003-09-18 | 2003-09-18 | Astrazeneca Ab | Novel compounds |
| EP1879448A2 (en) * | 2005-02-25 | 2008-01-23 | University of Chicago | Compositions and methods related to serpin spi6 |
-
2006
- 2006-09-26 US US11/527,373 patent/US20070104699A1/en not_active Abandoned
- 2006-09-26 WO PCT/CA2006/001582 patent/WO2007036028A1/en not_active Ceased
- 2006-09-26 JP JP2008532546A patent/JP2009509979A/ja active Pending
- 2006-09-26 EP EP06790747A patent/EP1940458A4/en not_active Withdrawn
- 2006-09-26 AU AU2006297036A patent/AU2006297036A1/en not_active Abandoned
- 2006-09-26 CA CA002623957A patent/CA2623957A1/en not_active Abandoned
-
2010
- 2010-09-07 US US12/876,574 patent/US20110083201A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Resch et al. | Transplanting marginal organs in the era of modern machine perfusion and advanced organ monitoring | |
| Stockmann et al. | Extracorporeal perfusion for the treatment of acute liver failure | |
| Nagamoto et al. | Transplantation of a human iPSC-derived hepatocyte sheet increases survival in mice with acute liver failure | |
| Kim et al. | Up to 9‐day survival and control of thrombocytopenia following alpha1, 3‐galactosyl transferase knockout swine liver xenotransplantation in baboons | |
| Machuca et al. | Advances in lung preservation | |
| BRPI0519783A2 (pt) | composições imunogênicas de pvc2 e métodos de produzir tais composições | |
| WO2005121369A3 (en) | Rna-containing microvesicles and methods therefor | |
| Watanabe et al. | GalT‐KO pig lungs are highly susceptible to acute vascular rejection in baboons, which may be mitigated by transgenic expression of hCD 47 on porcine blood vessels | |
| Zhang et al. | Artificial matrix helps neonatal cardiomyocytes restore injured myocardium in rats | |
| JP2005534430A5 (https=) | ||
| Kubicki et al. | Current status of pig lung xenotransplantation | |
| JP2009509979A5 (https=) | ||
| Bribriesco et al. | Experimental models of lung transplantation | |
| JP2005528124A5 (https=) | ||
| Wu et al. | Multiple gene modifications of pigs for overcoming obstacles of xenotransplantation | |
| Tatsumi et al. | Therapeutic effects of hepatocyte transplantation on hemophilia B | |
| JP2008526318A5 (https=) | ||
| WO2006130812A3 (en) | Plasma-depleted, non-red blood cell-depleted cord blood compositions and methods of use | |
| Rosenthal et al. | Techniques for intrasplenic hepatocyte transplantation in the large animal model | |
| Meyburg et al. | Liver cell transplantation in children | |
| Rust et al. | Hepatocyte transplantation in acute liver failure: A new therapeutic option for the next millennium? | |
| Zhou et al. | Experimental hepatocyte xenotransplantation—a comprehensive review of the literature | |
| Cai et al. | Liraglutide protects pancreatic islet from ischemic injury by reducing oxidative stress and activating Akt signaling during cold preservation to improve islet transplantation outcomes | |
| Waelzlein et al. | Hepatocyte transplantation for correction of inborn errors of metabolism | |
| CN102985532B (zh) | 胰岛的分离方法及用于保护胰岛组织的保护液 |