JP2004532978A5 - - Google Patents
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- JP2004532978A5 JP2004532978A5 JP2002572410A JP2002572410A JP2004532978A5 JP 2004532978 A5 JP2004532978 A5 JP 2004532978A5 JP 2002572410 A JP2002572410 A JP 2002572410A JP 2002572410 A JP2002572410 A JP 2002572410A JP 2004532978 A5 JP2004532978 A5 JP 2004532978A5
- Authority
- JP
- Japan
- Prior art keywords
- intensity
- cell
- detectable
- detecting
- energy released
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cell Anatomy 0.000 claims 29
- 238000000034 method Methods 0.000 claims 25
- 102000004169 proteins and genes Human genes 0.000 claims 18
- 108090000623 proteins and genes Proteins 0.000 claims 18
- 102000003688 G-Protein-Coupled Receptors Human genes 0.000 claims 12
- 108090000045 G-Protein-Coupled Receptors Proteins 0.000 claims 12
- 210000000805 cytoplasm Anatomy 0.000 claims 10
- 150000001875 compounds Chemical class 0.000 claims 7
- 230000004807 localization Effects 0.000 claims 6
- 102000003916 Arrestin Human genes 0.000 claims 4
- 108090000328 Arrestin Proteins 0.000 claims 4
- 230000000536 complexating effect Effects 0.000 claims 4
- 230000000694 effects Effects 0.000 claims 4
- 230000037361 pathway Effects 0.000 claims 4
- 239000000556 agonist Substances 0.000 claims 3
- 239000005557 antagonist Substances 0.000 claims 3
- 210000003956 transport vesicle Anatomy 0.000 claims 3
- 239000002131 composite material Substances 0.000 claims 2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27533901P | 2001-03-13 | 2001-03-13 | |
| US10/095,620 US20030013137A1 (en) | 2001-03-13 | 2002-03-12 | Automated methods of detecting receptor activity |
| PCT/US2002/007434 WO2002073199A1 (en) | 2001-03-13 | 2002-03-13 | Automated methods of detecting receptor activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004532978A JP2004532978A (ja) | 2004-10-28 |
| JP2004532978A5 true JP2004532978A5 (https=) | 2005-12-22 |
Family
ID=26790404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002572410A Pending JP2004532978A (ja) | 2001-03-13 | 2002-03-13 | 受容体活性を検出する自動化された方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US20030013137A1 (https=) |
| EP (1) | EP1386154A4 (https=) |
| JP (1) | JP2004532978A (https=) |
| AU (1) | AU2002248597B2 (https=) |
| CA (1) | CA2440683A1 (https=) |
| WO (1) | WO2002073199A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4969002B2 (ja) | 1999-06-08 | 2012-07-04 | ユニバーシテイ・オブ・アイオワ・リサーチ・フアウンデーシヨン | rAAV形質導入を増加するための化合物および方法 |
| US7163800B2 (en) * | 2000-11-03 | 2007-01-16 | Molecular Devices Corporation | Methods of screening compositions for G protein-coupled receptor desensitization inhibitory activity |
| US20050136431A1 (en) * | 2000-11-03 | 2005-06-23 | Oakley Robert H. | Methods of screening compositions for G protein-coupled receptor desensitization inhibitory activity |
| WO2003016486A2 (en) * | 2001-08-16 | 2003-02-27 | Sloan Kettering Institute For Cancer Research | Bio-synthetic photostimulators and methods of use |
| WO2003097795A2 (en) * | 2002-05-13 | 2003-11-27 | Norak Biosciences, Inc. | Constitutively translocating cell line |
| FR2851379B1 (fr) * | 2003-02-18 | 2008-02-01 | Cit Alcatel | Convertisseur en transfert direct d'energie |
| DE60325640D1 (de) * | 2002-10-25 | 2009-02-12 | Mds Analytical Technologies Us | Verfahren zur identifizierung von transmembranrezeptoragonisten mit reduzierter internalisierung |
| JP2007524379A (ja) * | 2003-03-31 | 2007-08-30 | ユニバーシテイ・オブ・アイオワ・リサーチ・フアウンデーシヨン | 上皮ナトリウムチャンネル関連障害のPharmico−遺伝子治療 |
| JP4734498B2 (ja) * | 2003-07-09 | 2011-07-27 | ライフ テクノロジーズ コーポレイション | タンパク質−タンパク質相互作用を解析する方法 |
| DE602005019318D1 (de) * | 2004-12-09 | 2010-03-25 | Cellomics Inc | Automatisiertes verfahren und system zur einstellung von bildanalyseparametern zur steuerung von bildanalyseoperationen |
| JP2007006830A (ja) * | 2005-07-01 | 2007-01-18 | Olympus Corp | 細胞内の顆粒状構造物の測定方法 |
| AU2007243184A1 (en) * | 2006-04-28 | 2007-11-08 | University Of Iowa Research Foundation | Methods and compounds to modulate parvovirus transduction of mammalian cells or to alter virus infection, method to identify a viral receptor or co-receptor |
| CN101063657A (zh) * | 2006-04-29 | 2007-10-31 | 中国科学院上海生命科学研究院 | 在活体细胞中筛选配体与受体结合的方法和系统 |
| CN102460150B (zh) | 2009-04-20 | 2015-05-20 | 新加坡科技研究局 | 囊泡系统及其用途 |
| US9096889B2 (en) | 2011-11-23 | 2015-08-04 | Promega Corporation | Compositions and methods for monitoring transmembrane trafficking |
| WO2014176524A2 (en) * | 2013-04-25 | 2014-10-30 | The Trustees Of The University Of Pennsylvania | Opioid detection based on high quality graphene transistor arrays and a synthetic mu receptor |
| WO2017139381A1 (en) | 2016-02-08 | 2017-08-17 | University Of Iowa Research Foundation | Methods to produce chimeric adeno-associated virus/bocavirus parvovirus |
| CA3198936A1 (en) | 2016-03-07 | 2017-09-14 | University Of Iowa Research Foundation | Aav-mediated expression using a synthetic promoter and enhancer |
| US12173305B2 (en) | 2016-05-26 | 2024-12-24 | University Of Iowa Research Foundation | cis and trans requirements for terminal resolution of human bocavirus 1 |
| US11142775B2 (en) | 2017-01-13 | 2021-10-12 | University Of Iowa Research Foundation | Bocaparvovirus small noncoding RNA and uses thereof |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4219335A (en) * | 1978-09-18 | 1980-08-26 | E. I. Du Pont De Nemours And Company | Immunochemical testing using tagged reagents |
| US4324633A (en) * | 1980-10-20 | 1982-04-13 | Lovejoy Curtis N | Electrolytic apparatus for treating continuous strip material |
| US5972629A (en) * | 1984-08-17 | 1999-10-26 | The Scripps Research Institute | Method for characterizing antigenic reactivity of biological sample |
| US4908773A (en) * | 1987-04-06 | 1990-03-13 | Genex Corporation | Computer designed stabilized proteins and method for producing same |
| US5744101A (en) * | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
| US5548661A (en) * | 1991-07-12 | 1996-08-20 | Price; Jeffrey H. | Operator independent image cytometer |
| US5324633A (en) * | 1991-11-22 | 1994-06-28 | Affymax Technologies N.V. | Method and apparatus for measuring binding affinity |
| DE4138621A1 (de) * | 1991-11-25 | 1993-06-17 | Boehringer Ingelheim Int | Verfahren zum screenen von substanzen mit modulierender wirkung auf einen rezeptorabhaengigen zellulaeren signaluebertragungsweg |
| US5670113A (en) * | 1991-12-20 | 1997-09-23 | Sibia Neurosciences, Inc. | Automated analysis equipment and assay method for detecting cell surface protein and/or cytoplasmic receptor function using same |
| US5912122A (en) * | 1993-06-04 | 1999-06-15 | Sibia Neurosciences, Inc. | Nucleic acids encoding and method for detecting nucleic acid encoding human metabotropic glutamate receptor subtype mGluR6 |
| CA2177388A1 (en) * | 1993-11-26 | 1995-06-01 | Lawrence B. Hendry | Design of drugs involving receptor-ligand-dna interactions |
| GB9403600D0 (en) * | 1994-02-24 | 1994-04-13 | Univ Glasgow | Three dimensional hormone structure |
| US5521705A (en) * | 1994-05-12 | 1996-05-28 | Oldenbourg; Rudolf | Polarized light microscopy |
| US5463564A (en) * | 1994-09-16 | 1995-10-31 | 3-Dimensional Pharmaceuticals, Inc. | System and method of automatically generating chemical compounds with desired properties |
| CA2215193C (en) * | 1995-03-17 | 2004-05-11 | Fujitsu Limited | Biochemical information processing apparatus, biochemical information processing method, and biochemical information recording medium |
| US6219622B1 (en) * | 1995-03-24 | 2001-04-17 | University Of Guelph | Computational method for designing chemical structures having common functional characteristics |
| US6100026A (en) * | 1995-04-25 | 2000-08-08 | Irori | Matrices with memories and uses thereof |
| US6017496A (en) * | 1995-06-07 | 2000-01-25 | Irori | Matrices with memories and uses thereof |
| US6025129A (en) * | 1995-04-25 | 2000-02-15 | Irori | Remotely programmable matrices with memories and uses thereof |
| US5545531A (en) * | 1995-06-07 | 1996-08-13 | Affymax Technologies N.V. | Methods for making a device for concurrently processing multiple biological chip assays |
| US5770176A (en) * | 1995-12-08 | 1998-06-23 | Chiron Diagnostics Corporation | Assays for functional nuclear receptors |
| US6027890A (en) * | 1996-01-23 | 2000-02-22 | Rapigene, Inc. | Methods and compositions for enhancing sensitivity in the analysis of biological-based assays |
| JP3733392B2 (ja) * | 1996-03-05 | 2006-01-11 | イーストマン コダック カンパニー | 画像の構図変化検出方法 |
| US5989835A (en) * | 1997-02-27 | 1999-11-23 | Cellomics, Inc. | System for cell-based screening |
| US5804436A (en) * | 1996-08-02 | 1998-09-08 | Axiom Biotechnologies, Inc. | Apparatus and method for real-time measurement of cellular response |
| US5891646A (en) * | 1997-06-05 | 1999-04-06 | Duke University | Methods of assaying receptor activity and constructs useful in such methods |
| US5972639A (en) * | 1997-07-24 | 1999-10-26 | Irori | Fluorescence-based assays for measuring cell proliferation |
| US6221612B1 (en) * | 1997-08-01 | 2001-04-24 | Aurora Biosciences Corporation | Photon reducing agents for use in fluorescence assays |
| US5987390A (en) * | 1997-10-28 | 1999-11-16 | Smithkline Beecham Corporation | Methods and systems for identification of protein classes |
| AU4992599A (en) * | 1998-07-13 | 2000-02-01 | Cellomics, Inc. | A system for cell-based screening |
| US6203987B1 (en) * | 1998-10-27 | 2001-03-20 | Rosetta Inpharmatics, Inc. | Methods for using co-regulated genesets to enhance detection and classification of gene expression patterns |
| US6221600B1 (en) * | 1999-10-08 | 2001-04-24 | Board Of Regents, The University Of Texas System | Combinatorial oligonucleotide PCR: a method for rapid, global expression analysis |
-
2002
- 2002-03-12 US US10/095,620 patent/US20030013137A1/en not_active Abandoned
- 2002-03-13 AU AU2002248597A patent/AU2002248597B2/en not_active Expired
- 2002-03-13 JP JP2002572410A patent/JP2004532978A/ja active Pending
- 2002-03-13 CA CA002440683A patent/CA2440683A1/en not_active Abandoned
- 2002-03-13 WO PCT/US2002/007434 patent/WO2002073199A1/en not_active Ceased
- 2002-03-13 EP EP02717608A patent/EP1386154A4/en not_active Withdrawn
-
2003
- 2003-07-29 US US10/629,176 patent/US20040029190A1/en not_active Abandoned
-
2005
- 2005-03-21 US US11/084,928 patent/US7455982B2/en not_active Expired - Fee Related
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