CA2440683A1 - Automated methods of detecting receptor activity - Google Patents
Automated methods of detecting receptor activity Download PDFInfo
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- CA2440683A1 CA2440683A1 CA002440683A CA2440683A CA2440683A1 CA 2440683 A1 CA2440683 A1 CA 2440683A1 CA 002440683 A CA002440683 A CA 002440683A CA 2440683 A CA2440683 A CA 2440683A CA 2440683 A1 CA2440683 A1 CA 2440683A1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1089—Design, preparation, screening or analysis of libraries using computer algorithms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5076—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving cell organelles, e.g. Golgi complex, endoplasmic reticulum
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
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- Biomedical Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
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- Analytical Chemistry (AREA)
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- General Physics & Mathematics (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27533901P | 2001-03-13 | 2001-03-13 | |
| US60/275,339 | 2001-03-13 | ||
| US10/095,620 | 2002-03-12 | ||
| US10/095,620 US20030013137A1 (en) | 2001-03-13 | 2002-03-12 | Automated methods of detecting receptor activity |
| PCT/US2002/007434 WO2002073199A1 (en) | 2001-03-13 | 2002-03-13 | Automated methods of detecting receptor activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2440683A1 true CA2440683A1 (en) | 2002-09-19 |
Family
ID=26790404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002440683A Abandoned CA2440683A1 (en) | 2001-03-13 | 2002-03-13 | Automated methods of detecting receptor activity |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US20030013137A1 (https=) |
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| JP4969002B2 (ja) | 1999-06-08 | 2012-07-04 | ユニバーシテイ・オブ・アイオワ・リサーチ・フアウンデーシヨン | ｒＡＡＶ形質導入を増加するための化合物および方法 |
| US20050136431A1 (en) * | 2000-11-03 | 2005-06-23 | Oakley Robert H. | Methods of screening compositions for G protein-coupled receptor desensitization inhibitory activity |
| US7163800B2 (en) * | 2000-11-03 | 2007-01-16 | Molecular Devices Corporation | Methods of screening compositions for G protein-coupled receptor desensitization inhibitory activity |
| AU2002323210A1 (en) * | 2001-08-16 | 2003-03-03 | Sloan Kettering Institute For Cancer Research | Bio-synthetic photostimulators and methods of use |
| CA2483692A1 (en) * | 2002-05-13 | 2003-11-27 | Molecular Devices Corporation | Constitutively translocating cell line |
| FR2851379B1 (fr) * | 2003-02-18 | 2008-02-01 | Cit Alcatel | Convertisseur en transfert direct d'energie |
| ATE419274T1 (de) * | 2002-10-25 | 2009-01-15 | Mds Analytical Technologies Us | Verfahren zur identifizierung von transmembranrezeptoragonisten mit reduzierter internalisierung |
| AU2004227358B8 (en) * | 2003-03-31 | 2009-12-10 | Targeted Genetics Corporation | Compounds and methods to enhance rAAV transduction |
| ATE534900T1 (de) * | 2003-07-09 | 2011-12-15 | Life Technologies Corp | Verfahren zum testen einer protein-protein- wechselwirkung |
| EP1820143B1 (en) * | 2004-12-09 | 2010-02-10 | Cellomics, Inc | Automated method and system for setting image analysis parameters to control image analysis operations |
| JP2007006830A (ja) * | 2005-07-01 | 2007-01-18 | Olympus Corp | 細胞内の顆粒状構造物の測定方法 |
| WO2007127464A2 (en) * | 2006-04-28 | 2007-11-08 | University Of Iowa Research Foundation | Methods and compounds to modulate parvovirus transduction of mammalian cells or to alter virus infection, method to identify a viral receptor or co-receptor |
| CN101063657A (zh) * | 2006-04-29 | 2007-10-31 | 中国科学院上海生命科学研究院 | 在活体细胞中筛选配体与受体结合的方法和系统 |
| CN102460150B (zh) | 2009-04-20 | 2015-05-20 | 新加坡科技研究局 | 囊泡系统及其用途 |
| US9096889B2 (en) | 2011-11-23 | 2015-08-04 | Promega Corporation | Compositions and methods for monitoring transmembrane trafficking |
| EP2989440A4 (en) * | 2013-04-25 | 2017-01-04 | The Trustees Of The University Of Pennsylvania | Opioid detection based on high quality graphene transistor arrays and a synthetic mu receptor |
| WO2017139381A1 (en) | 2016-02-08 | 2017-08-17 | University Of Iowa Research Foundation | Methods to produce chimeric adeno-associated virus/bocavirus parvovirus |
| CA3016985C (en) | 2016-03-07 | 2023-07-04 | University Of Iowa Research Foundation | Aav-mediated expression using a synthetic promoter and enhancer |
| WO2017205739A1 (en) | 2016-05-26 | 2017-11-30 | University Of Iowa Research Foundation | cis AND trans REQUIREMENTS FOR TERMINAL RESOLUTION OF HUMAN BOCAVIRUS 1 |
| US11142775B2 (en) | 2017-01-13 | 2021-10-12 | University Of Iowa Research Foundation | Bocaparvovirus small noncoding RNA and uses thereof |
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| US5744101A (en) * | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
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| US6219622B1 (en) * | 1995-03-24 | 2001-04-17 | University Of Guelph | Computational method for designing chemical structures having common functional characteristics |
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| JP2004532978A (ja) | 2004-10-28 |
| WO2002073199A1 (en) | 2002-09-19 |
| US20050181423A1 (en) | 2005-08-18 |
| EP1386154A1 (en) | 2004-02-04 |
| US20030013137A1 (en) | 2003-01-16 |
| US20040029190A1 (en) | 2004-02-12 |
| US7455982B2 (en) | 2008-11-25 |
| AU2002248597B2 (en) | 2008-01-31 |
| EP1386154A4 (en) | 2004-09-15 |
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