JP2004532265A5 - - Google Patents
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- Publication number
- JP2004532265A5 JP2004532265A5 JP2003500072A JP2003500072A JP2004532265A5 JP 2004532265 A5 JP2004532265 A5 JP 2004532265A5 JP 2003500072 A JP2003500072 A JP 2003500072A JP 2003500072 A JP2003500072 A JP 2003500072A JP 2004532265 A5 JP2004532265 A5 JP 2004532265A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- formula
- compound according
- compound
- trifluoromethylphenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 5
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 claims 4
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 2
- 235000019260 propionic acid Nutrition 0.000 claims 2
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 claims 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 1
- 229910052801 chlorine Inorganic materials 0.000 claims 1
- 239000000460 chlorine Substances 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000012453 solvate Substances 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0113232.3A GB0113232D0 (en) | 2001-05-31 | 2001-05-31 | Chemical process |
| PCT/EP2002/005884 WO2002096893A1 (en) | 2001-05-31 | 2002-05-29 | Process for preparing a thialzole ppar-ligand and polymorphs thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004532265A JP2004532265A (ja) | 2004-10-21 |
| JP2004532265A5 true JP2004532265A5 (https=) | 2005-12-22 |
Family
ID=9915637
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003500072A Pending JP2004532265A (ja) | 2001-05-31 | 2002-05-29 | チアゾールｐｐａｒリガンドおよびその多形体の調製方法 |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US7244849B2 (https=) |
| EP (1) | EP1395572B1 (https=) |
| JP (1) | JP2004532265A (https=) |
| KR (1) | KR20040007631A (https=) |
| CN (1) | CN1551871A (https=) |
| AT (1) | ATE315556T1 (https=) |
| AU (1) | AU2002317764B2 (https=) |
| BR (1) | BR0209892A (https=) |
| CA (1) | CA2448101A1 (https=) |
| CO (1) | CO5540298A2 (https=) |
| CZ (1) | CZ20033256A3 (https=) |
| DE (1) | DE60208682T2 (https=) |
| ES (1) | ES2256493T3 (https=) |
| GB (1) | GB0113232D0 (https=) |
| HU (1) | HUP0400117A3 (https=) |
| IL (1) | IL158641A0 (https=) |
| MX (1) | MXPA03010943A (https=) |
| NO (1) | NO20035313L (https=) |
| NZ (1) | NZ529486A (https=) |
| PL (1) | PL367114A1 (https=) |
| WO (1) | WO2002096893A1 (https=) |
| ZA (1) | ZA200308570B (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7105551B2 (en) * | 2000-12-20 | 2006-09-12 | Smithkline Beecham Corporation | Thiazole derivatives for treating PPAR related disorders |
| EP1517882A1 (en) | 2002-06-19 | 2005-03-30 | Eli Lilly And Company | Amide linker peroxisome proliferator activated receptor modulators |
| TW200400816A (en) | 2002-06-26 | 2004-01-16 | Lilly Co Eli | Tricyclic steroid hormone nuclear receptor modulators |
| AU2003261935A1 (en) | 2002-09-06 | 2004-03-29 | Takeda Pharmaceutical Company Limited | Furan or thiophene derivative and medicinal use thereof |
| EA010422B1 (ru) | 2003-08-01 | 2008-08-29 | Янссен Фармацевтика Н.В. | Замещённые индол-о-глюкозиды |
| WO2005097076A2 (en) * | 2004-04-09 | 2005-10-20 | Smithkline Beecham Corporation | Low dose pharmaceutical products |
| EP2044042A2 (en) * | 2006-01-10 | 2009-04-08 | SmithKline Beecham Corporation | Polymorphic forms of { 2-methyl-4- [4-methyl-2- (trifluoromethylphenyl) thiazol-5-methylthiol phenoxy}-acetic acid |
| WO2012168948A2 (en) * | 2011-06-06 | 2012-12-13 | Hetero Research Foundation | Process for febuxostat |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE451346T1 (de) * | 1998-03-10 | 2009-12-15 | Ono Pharmaceutical Co | Carbonsäurederivate und medikamente die diese als aktiven wirkstoff enthalten |
| PE20011010A1 (es) * | 1999-12-02 | 2001-10-18 | Glaxo Group Ltd | Oxazoles y tiazoles sustituidos como agonista del receptor activado por el proliferador de peroxisomas humano |
| US7091225B2 (en) * | 2000-12-20 | 2006-08-15 | Smithkline Beecham Corporation | Substituted oxazoles and thiazoles as hPPAR alpha agonists |
| GB0111523D0 (en) * | 2001-05-11 | 2001-07-04 | Glaxo Group Ltd | Chemical compounds |
| GB0113233D0 (en) * | 2001-05-31 | 2001-07-25 | Glaxo Group Ltd | Chemical compounds |
-
2001
- 2001-05-31 GB GBGB0113232.3A patent/GB0113232D0/en not_active Ceased
-
2002
- 2002-05-29 HU HU0400117A patent/HUP0400117A3/hu unknown
- 2002-05-29 BR BR0209892-0A patent/BR0209892A/pt not_active IP Right Cessation
- 2002-05-29 NZ NZ529486A patent/NZ529486A/en unknown
- 2002-05-29 CN CNA02810885XA patent/CN1551871A/zh active Pending
- 2002-05-29 JP JP2003500072A patent/JP2004532265A/ja active Pending
- 2002-05-29 EP EP02747330A patent/EP1395572B1/en not_active Expired - Lifetime
- 2002-05-29 IL IL15864102A patent/IL158641A0/xx unknown
- 2002-05-29 ES ES02747330T patent/ES2256493T3/es not_active Expired - Lifetime
- 2002-05-29 CZ CZ20033256A patent/CZ20033256A3/cs unknown
- 2002-05-29 MX MXPA03010943A patent/MXPA03010943A/es unknown
- 2002-05-29 CA CA002448101A patent/CA2448101A1/en not_active Abandoned
- 2002-05-29 WO PCT/EP2002/005884 patent/WO2002096893A1/en not_active Ceased
- 2002-05-29 AT AT02747330T patent/ATE315556T1/de not_active IP Right Cessation
- 2002-05-29 AU AU2002317764A patent/AU2002317764B2/en not_active Ceased
- 2002-05-29 KR KR10-2003-7015677A patent/KR20040007631A/ko not_active Ceased
- 2002-05-29 DE DE60208682T patent/DE60208682T2/de not_active Expired - Fee Related
- 2002-05-29 US US10/478,260 patent/US7244849B2/en not_active Expired - Fee Related
- 2002-05-29 PL PL02367114A patent/PL367114A1/xx not_active Application Discontinuation
-
2003
- 2003-11-03 ZA ZA200308570A patent/ZA200308570B/en unknown
- 2003-11-26 CO CO03104438A patent/CO5540298A2/es not_active Application Discontinuation
- 2003-11-28 NO NO20035313A patent/NO20035313L/no not_active Application Discontinuation