HUP0400117A3 - Polymorphs of 2-methyl-2-[4-({[-4methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-carbonyl]-amino}-methyl)-phenoxy]-propionic acid, process for their preparation, their use and pharmaceurical compositions containing them - Google Patents
Polymorphs of 2-methyl-2-[4-({[-4methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-carbonyl]-amino}-methyl)-phenoxy]-propionic acid, process for their preparation, their use and pharmaceurical compositions containing themInfo
- Publication number
- HUP0400117A3 HUP0400117A3 HU0400117A HUP0400117A HUP0400117A3 HU P0400117 A3 HUP0400117 A3 HU P0400117A3 HU 0400117 A HU0400117 A HU 0400117A HU P0400117 A HUP0400117 A HU P0400117A HU P0400117 A3 HUP0400117 A3 HU P0400117A3
- Authority
- HU
- Hungary
- Prior art keywords
- methyl
- pharmaceurical
- 4methyl
- polymorphs
- thiazol
- Prior art date
Links
- ILUPZUOBHCUBKB-UHFFFAOYSA-N 2-methyl-2-(4-{[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}carbonyl)amino]methyl}phenoxy)propanoic acid Chemical compound CC=1N=C(C=2C=CC(=CC=2)C(F)(F)F)SC=1C(=O)NCC1=CC=C(OC(C)(C)C(O)=O)C=C1 ILUPZUOBHCUBKB-UHFFFAOYSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Child & Adolescent Psychology (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0113232.3A GB0113232D0 (en) | 2001-05-31 | 2001-05-31 | Chemical process |
| PCT/EP2002/005884 WO2002096893A1 (en) | 2001-05-31 | 2002-05-29 | Process for preparing a thialzole ppar-ligand and polymorphs thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0400117A2 HUP0400117A2 (hu) | 2005-03-29 |
| HUP0400117A3 true HUP0400117A3 (en) | 2005-09-28 |
Family
ID=9915637
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0400117A HUP0400117A3 (en) | 2001-05-31 | 2002-05-29 | Polymorphs of 2-methyl-2-[4-({[-4methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-carbonyl]-amino}-methyl)-phenoxy]-propionic acid, process for their preparation, their use and pharmaceurical compositions containing them |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US7244849B2 (hu) |
| EP (1) | EP1395572B1 (hu) |
| JP (1) | JP2004532265A (hu) |
| KR (1) | KR20040007631A (hu) |
| CN (1) | CN1551871A (hu) |
| AT (1) | ATE315556T1 (hu) |
| AU (1) | AU2002317764B2 (hu) |
| BR (1) | BR0209892A (hu) |
| CA (1) | CA2448101A1 (hu) |
| CO (1) | CO5540298A2 (hu) |
| CZ (1) | CZ20033256A3 (hu) |
| DE (1) | DE60208682T2 (hu) |
| ES (1) | ES2256493T3 (hu) |
| GB (1) | GB0113232D0 (hu) |
| HU (1) | HUP0400117A3 (hu) |
| IL (1) | IL158641A0 (hu) |
| MX (1) | MXPA03010943A (hu) |
| NO (1) | NO20035313L (hu) |
| NZ (1) | NZ529486A (hu) |
| PL (1) | PL367114A1 (hu) |
| WO (1) | WO2002096893A1 (hu) |
| ZA (1) | ZA200308570B (hu) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7105551B2 (en) * | 2000-12-20 | 2006-09-12 | Smithkline Beecham Corporation | Thiazole derivatives for treating PPAR related disorders |
| CN1662487A (zh) | 2002-06-19 | 2005-08-31 | 伊莱利利公司 | 酰胺连接基过氧化物酶体增殖物激活受体调节剂 |
| TW200400816A (en) | 2002-06-26 | 2004-01-16 | Lilly Co Eli | Tricyclic steroid hormone nuclear receptor modulators |
| AU2003261935A1 (en) | 2002-09-06 | 2004-03-29 | Takeda Pharmaceutical Company Limited | Furan or thiophene derivative and medicinal use thereof |
| US7129220B2 (en) | 2003-08-01 | 2006-10-31 | Janssen Pharmaceutica N.V | Substituted indole-O-glucosides |
| US20070202179A1 (en) * | 2004-04-09 | 2007-08-30 | FAULKNER Patrick | Low Dose Pharmaceutical Products |
| JP2009523132A (ja) * | 2006-01-10 | 2009-06-18 | スミスクライン ビーチャム コーポレーション | ｛２−メチル−４−［４−メチル−２−（４−トリフルオロメチルフェニル）チアゾール−５−イルメチルチオ］フェノキシ｝−酢酸の多形体形態 |
| WO2012168948A2 (en) * | 2011-06-06 | 2012-12-13 | Hetero Research Foundation | Process for febuxostat |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE451346T1 (de) | 1998-03-10 | 2009-12-15 | Ono Pharmaceutical Co | Carbonsäurederivate und medikamente die diese als aktiven wirkstoff enthalten |
| PE20011010A1 (es) * | 1999-12-02 | 2001-10-18 | Glaxo Group Ltd | Oxazoles y tiazoles sustituidos como agonista del receptor activado por el proliferador de peroxisomas humano |
| US7091225B2 (en) * | 2000-12-20 | 2006-08-15 | Smithkline Beecham Corporation | Substituted oxazoles and thiazoles as hPPAR alpha agonists |
| GB0111523D0 (en) * | 2001-05-11 | 2001-07-04 | Glaxo Group Ltd | Chemical compounds |
| GB0113233D0 (en) * | 2001-05-31 | 2001-07-25 | Glaxo Group Ltd | Chemical compounds |
-
2001
- 2001-05-31 GB GBGB0113232.3A patent/GB0113232D0/en not_active Ceased
-
2002
- 2002-05-29 ES ES02747330T patent/ES2256493T3/es not_active Expired - Lifetime
- 2002-05-29 US US10/478,260 patent/US7244849B2/en not_active Expired - Fee Related
- 2002-05-29 PL PL02367114A patent/PL367114A1/xx not_active Application Discontinuation
- 2002-05-29 BR BR0209892-0A patent/BR0209892A/pt not_active IP Right Cessation
- 2002-05-29 MX MXPA03010943A patent/MXPA03010943A/es unknown
- 2002-05-29 IL IL15864102A patent/IL158641A0/xx unknown
- 2002-05-29 HU HU0400117A patent/HUP0400117A3/hu unknown
- 2002-05-29 EP EP02747330A patent/EP1395572B1/en not_active Expired - Lifetime
- 2002-05-29 AT AT02747330T patent/ATE315556T1/de not_active IP Right Cessation
- 2002-05-29 AU AU2002317764A patent/AU2002317764B2/en not_active Ceased
- 2002-05-29 JP JP2003500072A patent/JP2004532265A/ja active Pending
- 2002-05-29 CA CA002448101A patent/CA2448101A1/en not_active Abandoned
- 2002-05-29 CN CNA02810885XA patent/CN1551871A/zh active Pending
- 2002-05-29 WO PCT/EP2002/005884 patent/WO2002096893A1/en active IP Right Grant
- 2002-05-29 KR KR10-2003-7015677A patent/KR20040007631A/ko not_active Application Discontinuation
- 2002-05-29 NZ NZ529486A patent/NZ529486A/en unknown
- 2002-05-29 CZ CZ20033256A patent/CZ20033256A3/cs unknown
- 2002-05-29 DE DE60208682T patent/DE60208682T2/de not_active Expired - Fee Related
-
2003
- 2003-11-03 ZA ZA200308570A patent/ZA200308570B/en unknown
- 2003-11-26 CO CO03104438A patent/CO5540298A2/es not_active Application Discontinuation
- 2003-11-28 NO NO20035313A patent/NO20035313L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2004532265A (ja) | 2004-10-21 |
| NZ529486A (en) | 2005-12-23 |
| AU2002317764B2 (en) | 2005-01-06 |
| EP1395572A1 (en) | 2004-03-10 |
| DE60208682D1 (de) | 2006-04-06 |
| NO20035313D0 (no) | 2003-11-28 |
| DE60208682T2 (de) | 2006-08-24 |
| IL158641A0 (en) | 2004-05-12 |
| US20040242657A1 (en) | 2004-12-02 |
| HUP0400117A2 (hu) | 2005-03-29 |
| GB0113232D0 (en) | 2001-07-25 |
| CO5540298A2 (es) | 2005-07-29 |
| BR0209892A (pt) | 2004-06-08 |
| ATE315556T1 (de) | 2006-02-15 |
| ES2256493T3 (es) | 2006-07-16 |
| US7244849B2 (en) | 2007-07-17 |
| KR20040007631A (ko) | 2004-01-24 |
| WO2002096893A1 (en) | 2002-12-05 |
| CA2448101A1 (en) | 2002-12-05 |
| CZ20033256A3 (en) | 2004-04-14 |
| MXPA03010943A (es) | 2004-02-27 |
| EP1395572B1 (en) | 2006-01-11 |
| PL367114A1 (en) | 2005-02-21 |
| CN1551871A (zh) | 2004-12-01 |
| NO20035313L (no) | 2003-12-09 |
| ZA200308570B (en) | 2005-02-03 |
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