CO5540298A2 - Proceso para preparar un ligando de ppar de tiazol y polimorfos del mismo - Google Patents
Proceso para preparar un ligando de ppar de tiazol y polimorfos del mismoInfo
- Publication number
- CO5540298A2 CO5540298A2 CO03104438A CO03104438A CO5540298A2 CO 5540298 A2 CO5540298 A2 CO 5540298A2 CO 03104438 A CO03104438 A CO 03104438A CO 03104438 A CO03104438 A CO 03104438A CO 5540298 A2 CO5540298 A2 CO 5540298A2
- Authority
- CO
- Colombia
- Prior art keywords
- polymorphes
- tiazol
- prepare
- same
- ppar binding
- Prior art date
Links
- 102000003728 Peroxisome Proliferator-Activated Receptors Human genes 0.000 title 1
- 108090000029 Peroxisome Proliferator-Activated Receptors Proteins 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Chemical group C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 abstract 3
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Nutrition Science (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0113232.3A GB0113232D0 (en) | 2001-05-31 | 2001-05-31 | Chemical process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO5540298A2 true CO5540298A2 (es) | 2005-07-29 |
Family
ID=9915637
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO03104438A CO5540298A2 (es) | 2001-05-31 | 2003-11-26 | Proceso para preparar un ligando de ppar de tiazol y polimorfos del mismo |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US7244849B2 (https=) |
| EP (1) | EP1395572B1 (https=) |
| JP (1) | JP2004532265A (https=) |
| KR (1) | KR20040007631A (https=) |
| CN (1) | CN1551871A (https=) |
| AT (1) | ATE315556T1 (https=) |
| AU (1) | AU2002317764B2 (https=) |
| BR (1) | BR0209892A (https=) |
| CA (1) | CA2448101A1 (https=) |
| CO (1) | CO5540298A2 (https=) |
| CZ (1) | CZ20033256A3 (https=) |
| DE (1) | DE60208682T2 (https=) |
| ES (1) | ES2256493T3 (https=) |
| GB (1) | GB0113232D0 (https=) |
| HU (1) | HUP0400117A3 (https=) |
| IL (1) | IL158641A0 (https=) |
| MX (1) | MXPA03010943A (https=) |
| NO (1) | NO20035313L (https=) |
| NZ (1) | NZ529486A (https=) |
| PL (1) | PL367114A1 (https=) |
| WO (1) | WO2002096893A1 (https=) |
| ZA (1) | ZA200308570B (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7105551B2 (en) * | 2000-12-20 | 2006-09-12 | Smithkline Beecham Corporation | Thiazole derivatives for treating PPAR related disorders |
| EP1517882A1 (en) | 2002-06-19 | 2005-03-30 | Eli Lilly And Company | Amide linker peroxisome proliferator activated receptor modulators |
| TW200400816A (en) | 2002-06-26 | 2004-01-16 | Lilly Co Eli | Tricyclic steroid hormone nuclear receptor modulators |
| AU2003261935A1 (en) | 2002-09-06 | 2004-03-29 | Takeda Pharmaceutical Company Limited | Furan or thiophene derivative and medicinal use thereof |
| EA010422B1 (ru) | 2003-08-01 | 2008-08-29 | Янссен Фармацевтика Н.В. | Замещённые индол-о-глюкозиды |
| WO2005097076A2 (en) * | 2004-04-09 | 2005-10-20 | Smithkline Beecham Corporation | Low dose pharmaceutical products |
| EP2044042A2 (en) * | 2006-01-10 | 2009-04-08 | SmithKline Beecham Corporation | Polymorphic forms of { 2-methyl-4- [4-methyl-2- (trifluoromethylphenyl) thiazol-5-methylthiol phenoxy}-acetic acid |
| WO2012168948A2 (en) * | 2011-06-06 | 2012-12-13 | Hetero Research Foundation | Process for febuxostat |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE451346T1 (de) * | 1998-03-10 | 2009-12-15 | Ono Pharmaceutical Co | Carbonsäurederivate und medikamente die diese als aktiven wirkstoff enthalten |
| PE20011010A1 (es) * | 1999-12-02 | 2001-10-18 | Glaxo Group Ltd | Oxazoles y tiazoles sustituidos como agonista del receptor activado por el proliferador de peroxisomas humano |
| US7091225B2 (en) * | 2000-12-20 | 2006-08-15 | Smithkline Beecham Corporation | Substituted oxazoles and thiazoles as hPPAR alpha agonists |
| GB0111523D0 (en) * | 2001-05-11 | 2001-07-04 | Glaxo Group Ltd | Chemical compounds |
| GB0113233D0 (en) * | 2001-05-31 | 2001-07-25 | Glaxo Group Ltd | Chemical compounds |
-
2001
- 2001-05-31 GB GBGB0113232.3A patent/GB0113232D0/en not_active Ceased
-
2002
- 2002-05-29 HU HU0400117A patent/HUP0400117A3/hu unknown
- 2002-05-29 BR BR0209892-0A patent/BR0209892A/pt not_active IP Right Cessation
- 2002-05-29 NZ NZ529486A patent/NZ529486A/en unknown
- 2002-05-29 CN CNA02810885XA patent/CN1551871A/zh active Pending
- 2002-05-29 JP JP2003500072A patent/JP2004532265A/ja active Pending
- 2002-05-29 EP EP02747330A patent/EP1395572B1/en not_active Expired - Lifetime
- 2002-05-29 IL IL15864102A patent/IL158641A0/xx unknown
- 2002-05-29 ES ES02747330T patent/ES2256493T3/es not_active Expired - Lifetime
- 2002-05-29 CZ CZ20033256A patent/CZ20033256A3/cs unknown
- 2002-05-29 MX MXPA03010943A patent/MXPA03010943A/es unknown
- 2002-05-29 CA CA002448101A patent/CA2448101A1/en not_active Abandoned
- 2002-05-29 WO PCT/EP2002/005884 patent/WO2002096893A1/en not_active Ceased
- 2002-05-29 AT AT02747330T patent/ATE315556T1/de not_active IP Right Cessation
- 2002-05-29 AU AU2002317764A patent/AU2002317764B2/en not_active Ceased
- 2002-05-29 KR KR10-2003-7015677A patent/KR20040007631A/ko not_active Ceased
- 2002-05-29 DE DE60208682T patent/DE60208682T2/de not_active Expired - Fee Related
- 2002-05-29 US US10/478,260 patent/US7244849B2/en not_active Expired - Fee Related
- 2002-05-29 PL PL02367114A patent/PL367114A1/xx not_active Application Discontinuation
-
2003
- 2003-11-03 ZA ZA200308570A patent/ZA200308570B/en unknown
- 2003-11-26 CO CO03104438A patent/CO5540298A2/es not_active Application Discontinuation
- 2003-11-28 NO NO20035313A patent/NO20035313L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1395572B1 (en) | 2006-01-11 |
| AU2002317764B2 (en) | 2005-01-06 |
| JP2004532265A (ja) | 2004-10-21 |
| BR0209892A (pt) | 2004-06-08 |
| US7244849B2 (en) | 2007-07-17 |
| MXPA03010943A (es) | 2004-02-27 |
| NZ529486A (en) | 2005-12-23 |
| ES2256493T3 (es) | 2006-07-16 |
| PL367114A1 (en) | 2005-02-21 |
| CZ20033256A3 (en) | 2004-04-14 |
| WO2002096893A1 (en) | 2002-12-05 |
| CN1551871A (zh) | 2004-12-01 |
| DE60208682D1 (de) | 2006-04-06 |
| CA2448101A1 (en) | 2002-12-05 |
| NO20035313L (no) | 2003-12-09 |
| HUP0400117A3 (en) | 2005-09-28 |
| HUP0400117A2 (hu) | 2005-03-29 |
| EP1395572A1 (en) | 2004-03-10 |
| DE60208682T2 (de) | 2006-08-24 |
| IL158641A0 (en) | 2004-05-12 |
| NO20035313D0 (no) | 2003-11-28 |
| KR20040007631A (ko) | 2004-01-24 |
| ZA200308570B (en) | 2005-02-03 |
| ATE315556T1 (de) | 2006-02-15 |
| US20040242657A1 (en) | 2004-12-02 |
| GB0113232D0 (en) | 2001-07-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX338829B (es) | Metodo para preparar 3-halo-4,5-dihidro-1h-pirazoles. | |
| IS6614A (is) | Ný tríasólpýrimídínefnasambönd | |
| HRP990167B1 (en) | Sulphinic acid derivatives, method for producing them, and their use | |
| EA199900953A1 (ru) | ЗАМЕЩЕННЫЕ ПИРАЗОЛЫ, КАК ИНГИБИТОРЫ p38 КИНАЗЫ | |
| YU5503A (sh) | Nesteroidni supresori zapaljenja | |
| EA200100554A1 (ru) | Замещенные пиразолы как ингибиторы p38 киназы | |
| TR200800474T2 (tr) | Florfenikole aracı maddelerin hazırlanmasına ilişkin işlem. | |
| AR044706A2 (es) | Procedimientos para preparar 4-aminoquinolinas, inhibidores de cetp | |
| CY1107403T1 (el) | Μια μεθοδος δια την παρασκευη υπερινδοπριλης,των αναλογων ενωσεων αυτης και των αλατων αυτων με χρησιμοποιηση ενδιαμεσων ενωσεων 2,5-διοξο-οξαζολιδινης | |
| MXPA04001685A (es) | Derivados de sulfonilamino empleados como herbicida. | |
| DE69931753D1 (de) | Azoverbindungen sowie verfahren zur herstellung derselben | |
| ATE303384T1 (de) | 1-biaryl-1,8-naphthyridin-4-one als phosphodieseterase-inhibitoren | |
| CO5540298A2 (es) | Proceso para preparar un ligando de ppar de tiazol y polimorfos del mismo | |
| CO5720995A2 (es) | Compuesto novedoso | |
| MXPA05013905A (es) | Compuestos de quinazolinona sustituidos por arilamina. | |
| TR200201128T2 (tr) | PDE4 inhibitörleri olarak tetrahidrotiyopiranfitalazinon türevleri. | |
| DE59504085D1 (de) | Eisenphosphatierung unter verwendung von substituierten monocarbonsäuren | |
| MXPA04005129A (es) | Uso de diamina de acido piridin-2,4-dicarboxilico y de diaminas de acido pirimidin-4,6-dicarboxilico para la inhibicion selectiva de la colagenasa. | |
| ATE388957T1 (de) | Herstellung von siliziumverbrückten metallocenverbindungen | |
| IT1293777B1 (it) | Processo per la preparazione di tetraazamacrocicli | |
| ATE275149T1 (de) | Verfahren zur herstellung von taxanderivaten | |
| MXPA02012400A (es) | Heterociclos hetaril-substituidos. | |
| MX9701569A (es) | Pirimidin(tio)onas substituidas. | |
| MXPA02001406A (es) | Heterociclilos-2h-cromenos substituidos. | |
| MXPA05013034A (es) | N-alquinil-2-heteroariloxialquilamidas para uso como fungicidas. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Application refused |