JP2004531703A - 光学的（生物）化学センサーデバイスの作製方法 - Google Patents

光学的（生物）化学センサーデバイスの作製方法 Download PDF

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JP2004531703A
JP2004531703A JP2002565712A JP2002565712A JP2004531703A JP 2004531703 A JP2004531703 A JP 2004531703A JP 2002565712 A JP2002565712 A JP 2002565712A JP 2002565712 A JP2002565712 A JP 2002565712A JP 2004531703 A JP2004531703 A JP 2004531703A
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bio
chemical
spotting
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substrate material
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リューデル，ウルリッヒ
フリッキウス シュタンゲ，アンドレアス
ティルストルプ，カルステン
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ビール アクティーゼルスカブ
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G01N21/553—Attenuated total reflection and using surface plasmons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00387—Applications using probes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00527—Sheets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00585—Parallel processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/0059—Sequential processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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    • B01J2219/00583—Features relative to the processes being carried out
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00614—Delimitation of the attachment areas
    • B01J2219/00617—Delimitation of the attachment areas by chemical means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00623—Immobilisation or binding
    • B01J2219/00626—Covalent
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00632—Introduction of reactive groups to the surface
    • B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00677—Ex-situ synthesis followed by deposition on the substrate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
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    • B01J2219/0072—Organic compounds
    • B01J2219/00725—Peptides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00729—Peptide nucleic acids [PNA]
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    • B01J2219/00718—Type of compounds synthesised
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    • B01J2219/0074—Biological products
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
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    • B01J2219/0074—Biological products
    • B01J2219/00743—Cells
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nanotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Composite Materials (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
JP2002565712A 2001-02-16 2002-02-15 光学的（生物）化学センサーデバイスの作製方法 Pending JP2004531703A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200100263 2001-02-16
PCT/DK2002/000110 WO2002066162A1 (fr) 2001-02-16 2002-02-15 Procede de preparation de dispositifs de detection optique (bio)chimiques

Publications (1)

Publication Number Publication Date
JP2004531703A true JP2004531703A (ja) 2004-10-14

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JP2002565712A Pending JP2004531703A (ja) 2001-02-16 2002-02-15 光学的（生物）化学センサーデバイスの作製方法

Country Status (6)

Country Link
EP (1) EP1360007A1 (fr)
JP (1) JP2004531703A (fr)
KR (1) KR20030088029A (fr)
CN (1) CN1509210A (fr)
CA (1) CA2438345A1 (fr)
WO (1) WO2002066162A1 (fr)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005017153A (ja) * 2003-06-27 2005-01-20 Toyobo Co Ltd 金属基板チップに分子を固定化したアレイの作製方法
JP2007240501A (ja) * 2006-03-13 2007-09-20 Canon Inc 流速測定装置及び流速測定方法
WO2007132795A1 (fr) * 2006-05-12 2007-11-22 Canon Kabushiki Kaisha Élément de détection, dispositif de détection et procédé de détection
WO2008146569A1 (fr) * 2007-05-28 2008-12-04 Tanaka Kikinzoku Kogyo K.K. Biocapteur
JP2009510423A (ja) * 2005-09-27 2009-03-12 サントル・ナシオナル・ドゥ・ラ・ルシェルシュ・シアンティフィーク（セーエヌエールエス） 表面プラズモン共鳴（ｓｐｒ）検出用の新規チップ
JP2014199264A (ja) * 2007-12-20 2014-10-23 アボット ポイント オブ ケア インコーポレイテッド 感知のための固定化生物層の形成
JP2016197122A (ja) * 2012-11-13 2016-11-24 中国科学院理化技術研究所 表面プラズモン共鳴センサチップ及びその製造方法、応用
JP2019015610A (ja) * 2017-07-07 2019-01-31 日本化薬株式会社 バイオセンサ基板の接着に用いる紫外線硬化型樹脂組成物、それを用いたバイオセンサ基板

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US20050053954A1 (en) * 2002-11-01 2005-03-10 Brennan John D. Multicomponent protein microarrays
JP4008362B2 (ja) * 2003-02-12 2007-11-14 富士フイルム株式会社 表面電位測定装置
DE10328998A1 (de) * 2003-06-27 2005-01-20 Bayer Technology Services Gmbh IR-ATR basiertes Verfahren und Vorrichtung zur Analyse geringster Probenmengen
JP2005017155A (ja) * 2003-06-27 2005-01-20 Toyobo Co Ltd 金属基板上のアレイの作製方法
WO2005054548A2 (fr) 2003-11-28 2005-06-16 Invitrogen Corporation Procedes, compositions et kits de cristallisation de proteines
EP1907805B1 (fr) * 2005-07-18 2012-10-10 Koninklijke Philips Electronics N.V. Capteur de luminescence faisant appel a une structure de substrat multicouche
EP1811300B1 (fr) * 2005-12-23 2008-11-12 Micronas GmbH Puce de capteur avec des récepteurs inclus dans un réseau polymérique
EP2183595B1 (fr) * 2007-08-01 2016-04-20 Surfix BV Surfaces de silicium et de germanium repoussant les protéines
US20100236929A1 (en) * 2007-10-18 2010-09-23 Advanced Liquid Logic, Inc. Droplet Actuators, Systems and Methods
CN101672772B (zh) * 2009-09-09 2011-07-13 温州医学院 基于适配体的光化学生物传感器及其检测靶物质的方法
CN103123323B (zh) * 2011-11-18 2015-01-07 中国科学院大连化学物理研究所 指示剂置换比色传感器阵列用于多种阴离子检测的方法
EP2805151B1 (fr) 2012-01-19 2016-04-06 Universität Potsdam Optode pour determiner des parametres chimiques
US20180291204A1 (en) * 2015-05-18 2018-10-11 Sabic Global Technologies B.V. Improved dielectric strength compositions
CN109187703B (zh) * 2018-09-21 2020-09-08 扬州大学 一种基于非损伤微测技术的铜离子选择性微电极以及植物根尖铜离子流速测定方法

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EP0358991B2 (fr) * 1988-08-26 1998-02-11 Willi Möller AG Dispositif de test pour la détermination optique de cations, d'anions ou de substances ionogènes électriquement neutres et procédé de test utilisant ce dispositif
US5352712A (en) * 1989-05-11 1994-10-04 Borden, Inc. Ultraviolet radiation-curable coatings for optical fibers
US6170318B1 (en) * 1995-03-27 2001-01-09 California Institute Of Technology Methods of use for sensor based fluid detection devices
US5624711A (en) * 1995-04-27 1997-04-29 Affymax Technologies, N.V. Derivatization of solid supports and methods for oligomer synthesis
US6180288B1 (en) * 1997-03-21 2001-01-30 Kimberly-Clark Worldwide, Inc. Gel sensors and method of use thereof
US6269846B1 (en) * 1998-01-13 2001-08-07 Genetic Microsystems, Inc. Depositing fluid specimens on substrates, resulting ordered arrays, techniques for deposition of arrays
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AU5879400A (en) * 1999-06-29 2001-01-31 Chiron Corporation Arrays of biopolymeric agents and method for their production and use
CA2344946A1 (fr) * 2000-05-10 2001-11-10 Symyx Technologies, Inc. Theques de polymeres sur un substrat, methode de formation de theques de polymeres sur un substrat et methodes de caracterisation utilisant lesdites theques

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005017153A (ja) * 2003-06-27 2005-01-20 Toyobo Co Ltd 金属基板チップに分子を固定化したアレイの作製方法
JP2009510423A (ja) * 2005-09-27 2009-03-12 サントル・ナシオナル・ドゥ・ラ・ルシェルシュ・シアンティフィーク（セーエヌエールエス） 表面プラズモン共鳴（ｓｐｒ）検出用の新規チップ
JP2007240501A (ja) * 2006-03-13 2007-09-20 Canon Inc 流速測定装置及び流速測定方法
WO2007132795A1 (fr) * 2006-05-12 2007-11-22 Canon Kabushiki Kaisha Élément de détection, dispositif de détection et procédé de détection
US8045141B2 (en) 2006-05-12 2011-10-25 Canon Kabushiki Kaisha Detecting element, detecting device and detecting method
WO2008146569A1 (fr) * 2007-05-28 2008-12-04 Tanaka Kikinzoku Kogyo K.K. Biocapteur
JP2014199264A (ja) * 2007-12-20 2014-10-23 アボット ポイント オブ ケア インコーポレイテッド 感知のための固定化生物層の形成
US9441259B2 (en) 2007-12-20 2016-09-13 Abbott Point Of Care Inc. Formation of immobilized biological layers for sensing
JP2016197122A (ja) * 2012-11-13 2016-11-24 中国科学院理化技術研究所 表面プラズモン共鳴センサチップ及びその製造方法、応用
JP2019015610A (ja) * 2017-07-07 2019-01-31 日本化薬株式会社 バイオセンサ基板の接着に用いる紫外線硬化型樹脂組成物、それを用いたバイオセンサ基板

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CA2438345A1 (fr) 2002-08-29
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CN1509210A (zh) 2004-06-30
KR20030088029A (ko) 2003-11-15

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